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The map label for this gene is coaD

Identifier: 110633755

GI number: 110633755

Start: 1499418

End: 1499918

Strand: Direct

Name: coaD

Synonym: Meso_1402

Alternate gene names: 110633755

Gene position: 1499418-1499918 (Clockwise)

Preceding gene: 110633754

Following gene: 110633756

Centisome position: 33.98

GC content: 62.08

Gene sequence:

>501_bases
ATGACTGATCGCACCGCCTTTTATGCCGGCTCCTTCGATCCGCTTACCAACGGCCACCTCGACGTTCTGAAGGGGGCGTT
GGAACTTGCTGATACCGTGGTGATCGGCATCGGCATTCACCCGGGCAAAAAGCCGCTCTTTTCGTATGGCGAGCGCGTTG
CCCTGATCGAGCGCTCGGCCAAGGATGAGCTGGGCGCCGATGGCGGCCGCATCAAGGTGGTGGCTTTCGATAATCTGGTC
ATCGATGCTGCGCGCGTCCACGGTGCTTCGATCATGATCCGCGGCCTGCGTGACGGCACGGACCTCGACTACGAGATGCA
GATGGCGGGCATGAACCAGACCATGGCGCCGGAGCTGCTCACGGTTTTTCTGCCGGCGAGCCCATCGGTCCGCACCGTCA
CGGCTACGCTCGTGCGGCAGATCGCATCCATGGGCGGCAATGTCGCGCCTTTCGTGCCGGCCGTCGTGGCGGCGGCCCTG
AAAGAAAAATTTTCAGCCTAA

Upstream 100 bases:

>100_bases
CGGCACCTGTCTCATCAGTGGCGGACTGTGGCTTGCGCTCTCGAGGCGATAAGCCGAGAAGCGAATTGCCTTCCCTTGAT
AGGAGCGTTAGAAGCCGCCC

Downstream 100 bases:

>100_bases
CCGGGAGAGATTTGATGCGCCCTTTTTCTCGCTTTGCACCTCTTTGCGTTGCCGCCGTTTTGGCCTTCGGCTCCGCCGCA
CTTGCCGCGGAACCCGAAAA

Product: phosphopantetheine adenylyltransferase

Products: NA

Alternate protein names: Dephospho-CoA pyrophosphorylase; Pantetheine-phosphate adenylyltransferase; PPAT

Number of amino acids: Translated: 166; Mature: 165

Protein sequence:

>166_residues
MTDRTAFYAGSFDPLTNGHLDVLKGALELADTVVIGIGIHPGKKPLFSYGERVALIERSAKDELGADGGRIKVVAFDNLV
IDAARVHGASIMIRGLRDGTDLDYEMQMAGMNQTMAPELLTVFLPASPSVRTVTATLVRQIASMGGNVAPFVPAVVAAAL
KEKFSA

Sequences:

>Translated_166_residues
MTDRTAFYAGSFDPLTNGHLDVLKGALELADTVVIGIGIHPGKKPLFSYGERVALIERSAKDELGADGGRIKVVAFDNLV
IDAARVHGASIMIRGLRDGTDLDYEMQMAGMNQTMAPELLTVFLPASPSVRTVTATLVRQIASMGGNVAPFVPAVVAAAL
KEKFSA
>Mature_165_residues
TDRTAFYAGSFDPLTNGHLDVLKGALELADTVVIGIGIHPGKKPLFSYGERVALIERSAKDELGADGGRIKVVAFDNLVI
DAARVHGASIMIRGLRDGTDLDYEMQMAGMNQTMAPELLTVFLPASPSVRTVTATLVRQIASMGGNVAPFVPAVVAAALK
EKFSA

Specific function: Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate

COG id: COG0669

COG function: function code H; Phosphopantetheine adenylyltransferase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial CoaD family

Homologues:

Organism=Escherichia coli, GI1790065, Length=163, Percent_Identity=39.8773006134969, Blast_Score=133, Evalue=5e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): COAD_MESSB (Q11IH7)

Other databases:

- EMBL:   CP000390
- RefSeq:   YP_673963.1
- ProteinModelPortal:   Q11IH7
- SMR:   Q11IH7
- STRING:   Q11IH7
- GeneID:   4180994
- GenomeReviews:   CP000390_GR
- KEGG:   mes:Meso_1402
- NMPDR:   fig|266779.1.peg.2190
- eggNOG:   COG0669
- HOGENOM:   HBG288308
- OMA:   VRQIAAM
- ProtClustDB:   PRK00168
- BioCyc:   MSP266779:MESO_1402-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00151
- InterPro:   IPR004821
- InterPro:   IPR004820
- InterPro:   IPR001980
- InterPro:   IPR014729
- Gene3D:   G3DSA:3.40.50.620
- PRINTS:   PR01020
- TIGRFAMs:   TIGR01510
- TIGRFAMs:   TIGR00125

Pfam domain/function: PF01467 CTP_transf_2

EC number: =2.7.7.3

Molecular weight: Translated: 17558; Mature: 17426

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDRTAFYAGSFDPLTNGHLDVLKGALELADTVVIGIGIHPGKKPLFSYGERVALIERSA
CCCCCEEEECCCCCCCCCHHHHHHHHHHHHCEEEEEEECCCCCCHHHHCCCEEEEHHHCC
KDELGADGGRIKVVAFDNLVIDAARVHGASIMIRGLRDGTDLDYEMQMAGMNQTMAPELL
HHHCCCCCCEEEEEEECCEEEEHHHHCCCEEEEEECCCCCCCCEEEEECCCCCCCCCCEE
TVFLPASPSVRTVTATLVRQIASMGGNVAPFVPAVVAAALKEKFSA
EEEECCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TDRTAFYAGSFDPLTNGHLDVLKGALELADTVVIGIGIHPGKKPLFSYGERVALIERSA
CCCCEEEECCCCCCCCCHHHHHHHHHHHHCEEEEEEECCCCCCHHHHCCCEEEEHHHCC
KDELGADGGRIKVVAFDNLVIDAARVHGASIMIRGLRDGTDLDYEMQMAGMNQTMAPELL
HHHCCCCCCEEEEEEECCEEEEHHHHCCCEEEEEECCCCCCCCEEEEECCCCCCCCCCEE
TVFLPASPSVRTVTATLVRQIASMGGNVAPFVPAVVAAALKEKFSA
EEEECCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA