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The map label for this gene is yrhP [H]

Identifier: 110633754

GI number: 110633754

Start: 1498755

End: 1499369

Strand: Direct

Name: yrhP [H]

Synonym: Meso_1401

Alternate gene names: 110633754

Gene position: 1498755-1499369 (Clockwise)

Preceding gene: 110633753

Following gene: 110633755

Centisome position: 33.97

GC content: 62.11

Gene sequence:

>615_bases
ATGCCGGAAACCACTGCGCTGCTCTCCTACACGCTTGCCTGCATCGCGATTATCATCGTGCCCGGCCCGACGGTGACGGT
GATCATCGCCAATTCCATACGGCATGGTGCAAGGGCAGGGCTGCTCAATGTGCTGGGCACCCAGATTGGCCTCGCATCCA
TGCTCGGAGTGCTGGCGCTGGGCCTCAAGGCCATTGTGGCCGGCATGGGCAATCTCTTCGAGGTCGTGCGGCTGCTGGGG
GCCGCCTATCTCATCTGGATCGGCATTCGCATGTGGCGCTCCGACGGCTCGCTGGGTATGGCCGAGGCGCCGCCGCGTGG
GGACGGCTCGCTGATCCTGCAGGGCTTCGTGGTTTTCTGGTCGAACCCGAAGACCCTCATATTCTTCGGCGCCTTCATTC
CACAGTTCATCAATCCCGCAAATGGCACGGCGTGGCAGGCCCTGTTCCTGGGCGCCATTTTCATGTTCATCGCGGCCGTA
TCCGATTCCTTTTATGCCTTTGCGGCGGGCGGAGCGGGTGCGAAACTAACCAAGGCACGGGTGAGACTTGCGGAGCGCAT
CTCCGGCACCTGTCTCATCAGTGGCGGACTGTGGCTTGCGCTCTCGAGGCGATAA

Upstream 100 bases:

>100_bases
AGAACCTCGCCTGAATATTCCGTTCAGGCCGTGTTTAGAATTCTACCTTGCCAAGGCGGTGCGGCTATGGCTTTGCTTCG
ATCGTCACGGAGGCACTGAA

Downstream 100 bases:

>100_bases
GCCGAGAAGCGAATTGCCTTCCCTTGATAGGAGCGTTAGAAGCCGCCCATGACTGATCGCACCGCCTTTTATGCCGGCTC
CTTCGATCCGCTTACCAACG

Product: lysine exporter protein LysE/YggA

Products: homoserine lactone [Periplasm]; Proton [Cytoplasm]; homoserine [Periplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 204; Mature: 203

Protein sequence:

>204_residues
MPETTALLSYTLACIAIIIVPGPTVTVIIANSIRHGARAGLLNVLGTQIGLASMLGVLALGLKAIVAGMGNLFEVVRLLG
AAYLIWIGIRMWRSDGSLGMAEAPPRGDGSLILQGFVVFWSNPKTLIFFGAFIPQFINPANGTAWQALFLGAIFMFIAAV
SDSFYAFAAGGAGAKLTKARVRLAERISGTCLISGGLWLALSRR

Sequences:

>Translated_204_residues
MPETTALLSYTLACIAIIIVPGPTVTVIIANSIRHGARAGLLNVLGTQIGLASMLGVLALGLKAIVAGMGNLFEVVRLLG
AAYLIWIGIRMWRSDGSLGMAEAPPRGDGSLILQGFVVFWSNPKTLIFFGAFIPQFINPANGTAWQALFLGAIFMFIAAV
SDSFYAFAAGGAGAKLTKARVRLAERISGTCLISGGLWLALSRR
>Mature_203_residues
PETTALLSYTLACIAIIIVPGPTVTVIIANSIRHGARAGLLNVLGTQIGLASMLGVLALGLKAIVAGMGNLFEVVRLLGA
AYLIWIGIRMWRSDGSLGMAEAPPRGDGSLILQGFVVFWSNPKTLIFFGAFIPQFINPANGTAWQALFLGAIFMFIAAVS
DSFYAFAAGGAGAKLTKARVRLAERISGTCLISGGLWLALSRR

Specific function: Conducts The Efflux Of Homoserine And Homoserine Lactone. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the rht family [H]

Homologues:

Organism=Escherichia coli, GI48994979, Length=144, Percent_Identity=32.6388888888889, Blast_Score=81, Evalue=5e-17,
Organism=Escherichia coli, GI1788099, Length=142, Percent_Identity=28.169014084507, Blast_Score=69, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004778
- InterPro:   IPR001123 [H]

Pfam domain/function: PF01810 LysE [H]

EC number: NA

Molecular weight: Translated: 21454; Mature: 21323

Theoretical pI: Translated: 10.88; Mature: 10.88

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPETTALLSYTLACIAIIIVPGPTVTVIIANSIRHGARAGLLNVLGTQIGLASMLGVLAL
CCCHHHHHHHHHHHHHEEEECCCEEEEEEECHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
GLKAIVAGMGNLFEVVRLLGAAYLIWIGIRMWRSDGSLGMAEAPPRGDGSLILQGFVVFW
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCEEEEEEEEEE
SNPKTLIFFGAFIPQFINPANGTAWQALFLGAIFMFIAAVSDSFYAFAAGGAGAKLTKAR
CCCCEEEEEHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHH
VRLAERISGTCLISGGLWLALSRR
HHHHHHCCCEEEEECCEEEEEECC
>Mature Secondary Structure 
PETTALLSYTLACIAIIIVPGPTVTVIIANSIRHGARAGLLNVLGTQIGLASMLGVLAL
CCHHHHHHHHHHHHHEEEECCCEEEEEEECHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
GLKAIVAGMGNLFEVVRLLGAAYLIWIGIRMWRSDGSLGMAEAPPRGDGSLILQGFVVFW
HHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCCCCCCCCEEEEEEEEEE
SNPKTLIFFGAFIPQFINPANGTAWQALFLGAIFMFIAAVSDSFYAFAAGGAGAKLTKAR
CCCCEEEEEHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHHH
VRLAERISGTCLISGGLWLALSRR
HHHHHHCCCEEEEECCEEEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; homoserine [Cytoplasm] [C]

Specific reaction: Proton [Periplasm] + homoserine lactone [Cytoplasm] = Proton [Cytoplasm] + homoserine lactone [Periplasm] Proton [Periplasm] + homoserine [Cytoplasm] = Proton [Cytoplasm] + homoserine [Periplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9384377; 9308178 [H]