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The map label for this gene is dnaQ [H]

Identifier: 109948241

GI number: 109948241

Start: 1545571

End: 1546419

Strand: Reverse

Name: dnaQ [H]

Synonym: Hac_1778

Alternate gene names: 109948241

Gene position: 1546419-1545571 (Counterclockwise)

Preceding gene: 109948242

Following gene: 109948236

Centisome position: 99.52

GC content: 38.75

Gene sequence:

>849_bases
TTGCATAAAGATATTCAAGCCCTAATCGCTCGCTTAAAAAACCAGGATTTAAGCTTGGGTATGCTAGAAAAATCGCTCTC
TCGCCTTATCTATGATGAAATCAATTTGGAGTATTTAAAAGCGTGCGGGCTTAATTTCATAGAAACGAACGAAAATTTAA
TCACGCTCAAAAACCTTAAAACCCCCCTTAAAGATGAAGTTTTTTCCTTTATTGATTTAGAGACCACCGGATCTTGCCCC
CTAAAGCATGAGATTTTAGAAATTGGGGCCGTGCAAGTGAGCGGTGGGAAAATTATTAATCGTTTTGAAACCCTTGTGAA
AGTCAAAAGCGTACCCGATTATATTTCTGATCTTACAGGCATCGCTTATGAAGACACCCTAAACGCCCCAAGCGTGCATG
AAGCCTTGCAAGAATTGCGGCTTTTTTTGGGTAATAGCGTGTTTGTGGCCCATAACGCTAATTTTGATTATAATTTTTTA
GGGCGTTATTTTGTAGAAAAACTGCATTGCCCTTTATTGAATTTAAAGCTTTGCACTTTGGATTTATCCAGGCGCGCGAT
TTTATCCATGCGCTATTCTTTGAGCTTTTTAAAAGAGCTTTTAGGGTTTGGTATAGAGGTCAGCCATAGAGCCTATGCGG
ACGCTTTAGCGAGCTACAAGCTCTTTGAAATATGCCTATTAAACTTGCCTAATTATGTCAAAACCACGATAGATTTGATT
GATTTTTCCAAATGCGCTAACACTCTAATCAAAAGATCTCCAAGAGCCAGACACCAAGAGATCCCATCGCCATTCCCTCT
TTTTGAGAGAACAAAAGGTTTGTTAAATATCATAAAAGCAACCAGTTAA

Upstream 100 bases:

>100_bases
CAACAAGCGGATGTGGACATTGTGGTTTCAGGGAGTTATATTTTTAAATCTAAAGATCGTAAGCTAGCTATTGAAGGCTT
ACAGAATGCCAATAAATCTC

Downstream 100 bases:

>100_bases
ACAAAAGCCGTTTAATGGGGTTTGACTAGGGCTAGGATTTTTATTGTTTTTAGTTGTAAAACCTATTGAGATTATCGCTT
GTTTGCTTTAAAACGACTTG

Product: DNA polymerase III subunit epsilon

Products: NA

Alternate protein names: PolIII [H]

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MHKDIQALIARLKNQDLSLGMLEKSLSRLIYDEINLEYLKACGLNFIETNENLITLKNLKTPLKDEVFSFIDLETTGSCP
LKHEILEIGAVQVSGGKIINRFETLVKVKSVPDYISDLTGIAYEDTLNAPSVHEALQELRLFLGNSVFVAHNANFDYNFL
GRYFVEKLHCPLLNLKLCTLDLSRRAILSMRYSLSFLKELLGFGIEVSHRAYADALASYKLFEICLLNLPNYVKTTIDLI
DFSKCANTLIKRSPRARHQEIPSPFPLFERTKGLLNIIKATS

Sequences:

>Translated_282_residues
MHKDIQALIARLKNQDLSLGMLEKSLSRLIYDEINLEYLKACGLNFIETNENLITLKNLKTPLKDEVFSFIDLETTGSCP
LKHEILEIGAVQVSGGKIINRFETLVKVKSVPDYISDLTGIAYEDTLNAPSVHEALQELRLFLGNSVFVAHNANFDYNFL
GRYFVEKLHCPLLNLKLCTLDLSRRAILSMRYSLSFLKELLGFGIEVSHRAYADALASYKLFEICLLNLPNYVKTTIDLI
DFSKCANTLIKRSPRARHQEIPSPFPLFERTKGLLNIIKATS
>Mature_282_residues
MHKDIQALIARLKNQDLSLGMLEKSLSRLIYDEINLEYLKACGLNFIETNENLITLKNLKTPLKDEVFSFIDLETTGSCP
LKHEILEIGAVQVSGGKIINRFETLVKVKSVPDYISDLTGIAYEDTLNAPSVHEALQELRLFLGNSVFVAHNANFDYNFL
GRYFVEKLHCPLLNLKLCTLDLSRRAILSMRYSLSFLKELLGFGIEVSHRAYADALASYKLFEICLLNLPNYVKTTIDLI
DFSKCANTLIKRSPRARHQEIPSPFPLFERTKGLLNIIKATS

Specific function: Required for replicative DNA synthesis. This DNA polymerase also exhibits 3' to 5' exonuclease activity [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 exonuclease domain [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011708
- InterPro:   IPR006054
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR023223
- InterPro:   IPR004013
- InterPro:   IPR003141
- InterPro:   IPR006308
- InterPro:   IPR012337 [H]

Pfam domain/function: PF07733 DNA_pol3_alpha; PF00929 Exonuc_X-T; PF02811 PHP [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 31973; Mature: 31973

Theoretical pI: Translated: 7.84; Mature: 7.84

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHKDIQALIARLKNQDLSLGMLEKSLSRLIYDEINLEYLKACGLNFIETNENLITLKNLK
CCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHCCCCEEECCCCEEEECCCC
TPLKDEVFSFIDLETTGSCPLKHEILEIGAVQVSGGKIINRFETLVKVKSVPDYISDLTG
CCHHHHHHHHHCCCCCCCCCHHHHHHHHCCEEECCCHHHHHHHHHHHHHCCHHHHHHHCC
IAYEDTLNAPSVHEALQELRLFLGNSVFVAHNANFDYNFLGRYFVEKLHCPLLNLKLCTL
CCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCEEEEEE
DLSRRAILSMRYSLSFLKELLGFGIEVSHRAYADALASYKLFEICLLNLPNYVKTTIDLI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
DFSKCANTLIKRSPRARHQEIPSPFPLFERTKGLLNIIKATS
HHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MHKDIQALIARLKNQDLSLGMLEKSLSRLIYDEINLEYLKACGLNFIETNENLITLKNLK
CCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCHHHHHHCCCCEEECCCCEEEECCCC
TPLKDEVFSFIDLETTGSCPLKHEILEIGAVQVSGGKIINRFETLVKVKSVPDYISDLTG
CCHHHHHHHHHCCCCCCCCCHHHHHHHHCCEEECCCHHHHHHHHHHHHHCCHHHHHHHCC
IAYEDTLNAPSVHEALQELRLFLGNSVFVAHNANFDYNFLGRYFVEKLHCPLLNLKLCTL
CCCCCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHCCCCCCEEEEEE
DLSRRAILSMRYSLSFLKELLGFGIEVSHRAYADALASYKLFEICLLNLPNYVKTTIDLI
HHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHH
DFSKCANTLIKRSPRARHQEIPSPFPLFERTKGLLNIIKATS
HHHHHHHHHHHCCCCHHHHCCCCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9826752; 10360571 [H]