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The map label for this gene is yhdT [H]

Identifier: 109948217

GI number: 109948217

Start: 1524893

End: 1526212

Strand: Reverse

Name: yhdT [H]

Synonym: Hac_1750

Alternate gene names: 109948217

Gene position: 1526212-1524893 (Counterclockwise)

Preceding gene: 109948218

Following gene: 109948216

Centisome position: 98.22

GC content: 41.29

Gene sequence:

>1320_bases
TTGGATCCGTCTGAGTCGATTTTGATGTTGATGGTTGCTTTTTTGTTAGTGTTGTTGAATGCTTTTTTTGTGCTTTCAGA
GTTTGCTCTTGTGAAAGTGCGTAAAACCCGTTTAGAAGAGCTGGTTAAAATCGGTAATTCCAACGCTAAACTCGCTTTAG
AAATGAGTCAGAGACTAGACACTTATTTGAGCGCGACGCAATTGGGCATAACGCTTTCTTCATTGGCTTTGGGTTGGGTG
GGTGAGCCCACTATCGCGAGGTTATTAGCCACGCTGTTTCAATCTATAAATTTGGAAGACAACTCCCTTTTTATCCATTC
AATGAGCGTGGTGGTGGCGTTTTTAAGCATCACTTTTTTGCATGTCGTGTTGGGCGAAATTGTGCCCAAATCTTTAGCGA
TCGCCAAATCTGAAAAAGCCACTCTTTTTATTGCGCGCCCTTTGCATGTGTTTTGGGTGGCGTTTTACCCGGTGGTGCGC
CTGTTTGATGTGATCGCTTATTTCTTTTTAAGAAAGATGGGCGTTAATCCCAAAGAGCATGAGGGCACGCATTCTGAAGA
AGAGTTAAAAATCATTGTGGGCGAGAGCTTGAGGGAGGGCATTATTGATTCAGTGGAGGGCGAGATCATTAAAAATGCAG
TGGATTTTTCTGACACAAGCGCTAAAGAGATTATGACCCCACGAAAAGACATGGTGTGCTTAGATGAAGAAAACAGCTAT
GAAGAAAATATAGACATTGTTTTAAAAAGCCGTTTCACGCGCTACCCTTATTGTAAGGGATCTAAAGACAATATTATCGG
CATGGTGCATATCAGAGATTTGCTTTCTCGCTCCCTTTTTACCCCCAAAATGCATGATTTCAAGCAAATCGTCAGAAAAA
TGATCATTGTCCCAGAGAGTGCATCTATTTCTCAAATCCTTATTAAAATGAAAAAAGAACAAATCCATACTGCTTTAGTG
ATTGATGAATACGGCGGCACAGCTGGGTTGCTCACTATGGAAGATATTATTGAAGAGATTATGGGGGAGATTAGCGATGA
ATACGATTTAAAGCAAGAGGGCGTGAATAAACTTGAAGAAGGCGTGTTTGAATTAGAGGGCATGTTGGATTTAGAGAGTG
TAGAAGAAGTGCTTCATATCCAATTTGACAAAGAATGCGAGCAGGTAACGCTTGGGGGTTATGTTTTTAGCTTGTTAGAG
CGCATGCCTATGGAAGGGGATACCATCATTTCGCATGGGTATGCCTTTGAAGTTTTAAGCGTGGATGGAGCGAGGATAAA
ACGCTTGAAAGCGATTAAAGAAAATAAGGAAGAAGATTAA

Upstream 100 bases:

>100_bases
GGCCTGATTTTAAAGTTAGGCTTAATCTTTTATGTTAAAATTGTAAGATTTTAGTTATCGTTAGGTTTTTTAAAATCATG
GGGAGGATCAAGGAGCTTAT

Downstream 100 bases:

>100_bases
AATGAAAAAAACCATTCTCTTTGCATTGAGCTTGTTGTGCGGTAGTTTTTTAAACGCTGTGGATGAAAACCCTAAAAATA
TCCAAGAAAAAACCAAGCCT

Product: hemolysin domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 439; Mature: 439

Protein sequence:

>439_residues
MDPSESILMLMVAFLLVLLNAFFVLSEFALVKVRKTRLEELVKIGNSNAKLALEMSQRLDTYLSATQLGITLSSLALGWV
GEPTIARLLATLFQSINLEDNSLFIHSMSVVVAFLSITFLHVVLGEIVPKSLAIAKSEKATLFIARPLHVFWVAFYPVVR
LFDVIAYFFLRKMGVNPKEHEGTHSEEELKIIVGESLREGIIDSVEGEIIKNAVDFSDTSAKEIMTPRKDMVCLDEENSY
EENIDIVLKSRFTRYPYCKGSKDNIIGMVHIRDLLSRSLFTPKMHDFKQIVRKMIIVPESASISQILIKMKKEQIHTALV
IDEYGGTAGLLTMEDIIEEIMGEISDEYDLKQEGVNKLEEGVFELEGMLDLESVEEVLHIQFDKECEQVTLGGYVFSLLE
RMPMEGDTIISHGYAFEVLSVDGARIKRLKAIKENKEED

Sequences:

>Translated_439_residues
MDPSESILMLMVAFLLVLLNAFFVLSEFALVKVRKTRLEELVKIGNSNAKLALEMSQRLDTYLSATQLGITLSSLALGWV
GEPTIARLLATLFQSINLEDNSLFIHSMSVVVAFLSITFLHVVLGEIVPKSLAIAKSEKATLFIARPLHVFWVAFYPVVR
LFDVIAYFFLRKMGVNPKEHEGTHSEEELKIIVGESLREGIIDSVEGEIIKNAVDFSDTSAKEIMTPRKDMVCLDEENSY
EENIDIVLKSRFTRYPYCKGSKDNIIGMVHIRDLLSRSLFTPKMHDFKQIVRKMIIVPESASISQILIKMKKEQIHTALV
IDEYGGTAGLLTMEDIIEEIMGEISDEYDLKQEGVNKLEEGVFELEGMLDLESVEEVLHIQFDKECEQVTLGGYVFSLLE
RMPMEGDTIISHGYAFEVLSVDGARIKRLKAIKENKEED
>Mature_439_residues
MDPSESILMLMVAFLLVLLNAFFVLSEFALVKVRKTRLEELVKIGNSNAKLALEMSQRLDTYLSATQLGITLSSLALGWV
GEPTIARLLATLFQSINLEDNSLFIHSMSVVVAFLSITFLHVVLGEIVPKSLAIAKSEKATLFIARPLHVFWVAFYPVVR
LFDVIAYFFLRKMGVNPKEHEGTHSEEELKIIVGESLREGIIDSVEGEIIKNAVDFSDTSAKEIMTPRKDMVCLDEENSY
EENIDIVLKSRFTRYPYCKGSKDNIIGMVHIRDLLSRSLFTPKMHDFKQIVRKMIIVPESASISQILIKMKKEQIHTALV
IDEYGGTAGLLTMEDIIEEIMGEISDEYDLKQEGVNKLEEGVFELEGMLDLESVEEVLHIQFDKECEQVTLGGYVFSLLE
RMPMEGDTIISHGYAFEVLSVDGARIKRLKAIKENKEED

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=387, Percent_Identity=40.8268733850129, Blast_Score=291, Evalue=6e-79,
Organism=Escherichia coli, GI1790664, Length=422, Percent_Identity=24.4075829383886, Blast_Score=151, Evalue=9e-38,
Organism=Escherichia coli, GI1786879, Length=248, Percent_Identity=30.6451612903226, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI145693175, Length=419, Percent_Identity=24.582338902148, Blast_Score=122, Evalue=7e-29,
Organism=Escherichia coli, GI87082033, Length=242, Percent_Identity=23.9669421487603, Blast_Score=99, Evalue=6e-22,
Organism=Escherichia coli, GI1788119, Length=243, Percent_Identity=25.1028806584362, Blast_Score=70, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6324512, Length=250, Percent_Identity=27.2, Blast_Score=65, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 49596; Mature: 49596

Theoretical pI: Translated: 4.67; Mature: 4.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.9 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.9 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDPSESILMLMVAFLLVLLNAFFVLSEFALVKVRKTRLEELVKIGNSNAKLALEMSQRLD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHH
TYLSATQLGITLSSLALGWVGEPTIARLLATLFQSINLEDNSLFIHSMSVVVAFLSITFL
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHH
HVVLGEIVPKSLAIAKSEKATLFIARPLHVFWVAFYPVVRLFDVIAYFFLRKMGVNPKEH
HHHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
EGTHSEEELKIIVGESLREGIIDSVEGEIIKNAVDFSDTSAKEIMTPRKDMVCLDEENSY
CCCCCHHHEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCEEEECCCCCC
EENIDIVLKSRFTRYPYCKGSKDNIIGMVHIRDLLSRSLFTPKMHDFKQIVRKMIIVPES
CCCHHHHEEHHCCCCCCCCCCCCCEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCC
ASISQILIKMKKEQIHTALVIDEYGGTAGLLTMEDIIEEIMGEISDEYDLKQEGVNKLEE
CHHHHHHHHHHHHHHHEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
GVFELEGMLDLESVEEVLHIQFDKECEQVTLGGYVFSLLERMPMEGDTIISHGYAFEVLS
HHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCEEECCCEEEEEE
VDGARIKRLKAIKENKEED
CCHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MDPSESILMLMVAFLLVLLNAFFVLSEFALVKVRKTRLEELVKIGNSNAKLALEMSQRLD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHHH
TYLSATQLGITLSSLALGWVGEPTIARLLATLFQSINLEDNSLFIHSMSVVVAFLSITFL
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHH
HVVLGEIVPKSLAIAKSEKATLFIARPLHVFWVAFYPVVRLFDVIAYFFLRKMGVNPKEH
HHHHHHHHHHHHHHCCCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
EGTHSEEELKIIVGESLREGIIDSVEGEIIKNAVDFSDTSAKEIMTPRKDMVCLDEENSY
CCCCCHHHEEEEECHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCCEEEECCCCCC
EENIDIVLKSRFTRYPYCKGSKDNIIGMVHIRDLLSRSLFTPKMHDFKQIVRKMIIVPES
CCCHHHHEEHHCCCCCCCCCCCCCEEEHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCC
ASISQILIKMKKEQIHTALVIDEYGGTAGLLTMEDIIEEIMGEISDEYDLKQEGVNKLEE
CHHHHHHHHHHHHHHHEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHH
GVFELEGMLDLESVEEVLHIQFDKECEQVTLGGYVFSLLERMPMEGDTIISHGYAFEVLS
HHHHHHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCCCCEEECCCEEEEEE
VDGARIKRLKAIKENKEED
CCHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]