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The map label for this gene is katA [H]

Identifier: 109947763

GI number: 109947763

Start: 1071496

End: 1073013

Strand: Reverse

Name: katA [H]

Synonym: Hac_1240

Alternate gene names: 109947763

Gene position: 1073013-1071496 (Counterclockwise)

Preceding gene: 109947765

Following gene: 109947762

Centisome position: 69.05

GC content: 41.63

Gene sequence:

>1518_bases
ATGGTTAATAAAGACTTGAAACAAACTACTGCTTTTGGTGCTCCCGTTTGGGATGATAACAATGTGGTTACGGTTGGTCC
TAGAGGTCCTGTTCTTTTACAAAGCACTTGGTTTTTGGAAAAGTTAGCGGCGTTTGACAGAGAAAGGATCCCTGAGAGGG
TTGTGCACGCTAAAGGAAGTGGGGCTTATGGCACTTTCACAGTGACTAAAGACATCACTAAATACACTAAAGCGAAAATT
TTCTCTAAAGTTGGCAAAAAAACGGAATGCTTTTTCAGATTTTCAACCGTTGCTGGTGAAAGAGGCTTTGCGGATGCAGT
GAGAGACCCTAGGGGTTTTGCGATGAAGTATTACACTGAGGAGGGTAATTGGGATTTGGTAGGGAATAACACACCAATCT
TTTTTATCCGTGATCCGATCAAATTCCCTGATTTTATCCACACTCAAAAAAGAGACCCTCAAACCAATTTGCATAGCCCT
ACTATGGTATGGGATTTTTGGAGCAATGTCCCTGAAAGCTTGCACCAGGTTACATGGGTTATGGGCGATAGGGGGATCCC
TAAAACTTACCGTCATATGGATGGTTTTGGCAGCCACACTTTTAGCCTTATCAACGCTAAAGATGAGCGTGTTTGGGTAA
AATTCCACTTCAAATGCATGCAAGGTTTGGCACACTTGACTAACGAAGAAGCCGCAGAAATCAGAAAAAATGATCCGGAT
TCACACCAAAGAGATCTATACGACGCGATCGCTAGAGGGGATTTTCCGAAATGGAAGATGTGCATTCAAGTGATGCCAGA
AGAAGATGCTAAAAAGTATCGATTCCATCCGTTTGATGTCACTAAAGTTTGGAGTCAAAAAGATTATCCTTTAATGGAAG
TGGGCATTGTAGAGTTGAATAAAAATCCGGAAAACTATTTCGCAGAAGTGGAGCAAGCGGCATTCACACCAGCCAATGTC
GTTCCTGGAATTGGTTATAGCCCTGATAGGATGTTGCAAGGGCGCTTATTCTCTTATGGGGATACACACCGCTACCGATT
AGGTGTTAACTACGCTCAAATACCGGTCAATAAACCAAGATGCCCATTCCACTCTTCTAGCAGAGATGGTCATATGCAAA
ATGGATACTATGGCGCTTTACAAAACTACACGCCTAGCTCATTGCCCGGCTATAAAGAAGACAAGAGTGCAAGGGATCCT
AAACTCAATTTAACTCACATTGAAAAAGAATATGAAGTGTGGAATTGGGATTTTAGGGCTGACGATAGCGATTACTACAC
CCAACCAGGCGATCTATACCGCTTGATGAAACCGGATGAAAAAGAAAGGTTGTATGATACTATCGGAGGTTCTTTAGCGC
ATGTTGAGCATAAAGAAATCGTGGATAAGCAATTGGAACATTTCAGAAAAGCTGATCCCAAATACGCTGAGGGAGTTAAA
AAAGCTCTTGAAAAACACCAAAAAATGATGAAAGACATGCATATGAAAGATATGTCTCACACAAAAAAGAAAAAGTAA

Upstream 100 bases:

>100_bases
GTGTATTGTTGGAGTTCGTATAACAAATTGTGCGACAATCACTCAAGTAATTGGCTAACGCTAAATTACGAAATTTTGAA
TTCAATACAAAGGAAGAAAG

Downstream 100 bases:

>100_bases
GCTTTTTCTTTAGGCGTCTTTATTTCTAGGGGTGCTGTGTCTTTTTAAATTTAGGTTTTTGAGATAGCCACCAATCCTTA
AAGGCTTGGTGGTTTGTCTT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 505; Mature: 505

Protein sequence:

>505_residues
MVNKDLKQTTAFGAPVWDDNNVVTVGPRGPVLLQSTWFLEKLAAFDRERIPERVVHAKGSGAYGTFTVTKDITKYTKAKI
FSKVGKKTECFFRFSTVAGERGFADAVRDPRGFAMKYYTEEGNWDLVGNNTPIFFIRDPIKFPDFIHTQKRDPQTNLHSP
TMVWDFWSNVPESLHQVTWVMGDRGIPKTYRHMDGFGSHTFSLINAKDERVWVKFHFKCMQGLAHLTNEEAAEIRKNDPD
SHQRDLYDAIARGDFPKWKMCIQVMPEEDAKKYRFHPFDVTKVWSQKDYPLMEVGIVELNKNPENYFAEVEQAAFTPANV
VPGIGYSPDRMLQGRLFSYGDTHRYRLGVNYAQIPVNKPRCPFHSSSRDGHMQNGYYGALQNYTPSSLPGYKEDKSARDP
KLNLTHIEKEYEVWNWDFRADDSDYYTQPGDLYRLMKPDEKERLYDTIGGSLAHVEHKEIVDKQLEHFRKADPKYAEGVK
KALEKHQKMMKDMHMKDMSHTKKKK

Sequences:

>Translated_505_residues
MVNKDLKQTTAFGAPVWDDNNVVTVGPRGPVLLQSTWFLEKLAAFDRERIPERVVHAKGSGAYGTFTVTKDITKYTKAKI
FSKVGKKTECFFRFSTVAGERGFADAVRDPRGFAMKYYTEEGNWDLVGNNTPIFFIRDPIKFPDFIHTQKRDPQTNLHSP
TMVWDFWSNVPESLHQVTWVMGDRGIPKTYRHMDGFGSHTFSLINAKDERVWVKFHFKCMQGLAHLTNEEAAEIRKNDPD
SHQRDLYDAIARGDFPKWKMCIQVMPEEDAKKYRFHPFDVTKVWSQKDYPLMEVGIVELNKNPENYFAEVEQAAFTPANV
VPGIGYSPDRMLQGRLFSYGDTHRYRLGVNYAQIPVNKPRCPFHSSSRDGHMQNGYYGALQNYTPSSLPGYKEDKSARDP
KLNLTHIEKEYEVWNWDFRADDSDYYTQPGDLYRLMKPDEKERLYDTIGGSLAHVEHKEIVDKQLEHFRKADPKYAEGVK
KALEKHQKMMKDMHMKDMSHTKKKK
>Mature_505_residues
MVNKDLKQTTAFGAPVWDDNNVVTVGPRGPVLLQSTWFLEKLAAFDRERIPERVVHAKGSGAYGTFTVTKDITKYTKAKI
FSKVGKKTECFFRFSTVAGERGFADAVRDPRGFAMKYYTEEGNWDLVGNNTPIFFIRDPIKFPDFIHTQKRDPQTNLHSP
TMVWDFWSNVPESLHQVTWVMGDRGIPKTYRHMDGFGSHTFSLINAKDERVWVKFHFKCMQGLAHLTNEEAAEIRKNDPD
SHQRDLYDAIARGDFPKWKMCIQVMPEEDAKKYRFHPFDVTKVWSQKDYPLMEVGIVELNKNPENYFAEVEQAAFTPANV
VPGIGYSPDRMLQGRLFSYGDTHRYRLGVNYAQIPVNKPRCPFHSSSRDGHMQNGYYGALQNYTPSSLPGYKEDKSARDP
KLNLTHIEKEYEVWNWDFRADDSDYYTQPGDLYRLMKPDEKERLYDTIGGSLAHVEHKEIVDKQLEHFRKADPKYAEGVK
KALEKHQKMMKDMHMKDMSHTKKKK

Specific function: Decomposes hydrogen peroxide into water and oxygen; serves to protect cells from the toxic effects of hydrogen peroxide [H]

COG id: COG0753

COG function: function code P; Catalase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the catalase family [H]

Homologues:

Organism=Homo sapiens, GI4557014, Length=482, Percent_Identity=54.149377593361, Blast_Score=504, Evalue=1e-143,
Organism=Escherichia coli, GI48994891, Length=482, Percent_Identity=43.3609958506224, Blast_Score=382, Evalue=1e-107,
Organism=Caenorhabditis elegans, GI71998444, Length=482, Percent_Identity=52.4896265560166, Blast_Score=513, Evalue=1e-145,
Organism=Caenorhabditis elegans, GI25147792, Length=477, Percent_Identity=51.1530398322851, Blast_Score=491, Evalue=1e-139,
Organism=Caenorhabditis elegans, GI25151141, Length=477, Percent_Identity=51.1530398322851, Blast_Score=490, Evalue=1e-139,
Organism=Saccharomyces cerevisiae, GI6320462, Length=502, Percent_Identity=45.2191235059761, Blast_Score=402, Evalue=1e-113,
Organism=Saccharomyces cerevisiae, GI6321525, Length=386, Percent_Identity=45.3367875647668, Blast_Score=343, Evalue=3e-95,
Organism=Drosophila melanogaster, GI17981717, Length=453, Percent_Identity=54.083885209713, Blast_Score=471, Evalue=1e-133,
Organism=Drosophila melanogaster, GI19920968, Length=395, Percent_Identity=53.1645569620253, Blast_Score=432, Evalue=1e-121,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002226
- InterPro:   IPR020835
- InterPro:   IPR010582
- InterPro:   IPR018028
- InterPro:   IPR011614 [H]

Pfam domain/function: PF00199 Catalase; PF06628 Catalase-rel [H]

EC number: =1.11.1.6 [H]

Molecular weight: Translated: 58642; Mature: 58642

Theoretical pI: Translated: 8.98; Mature: 8.98

Prosite motif: PS00437 CATALASE_1 ; PS00438 CATALASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVNKDLKQTTAFGAPVWDDNNVVTVGPRGPVLLQSTWFLEKLAAFDRERIPERVVHAKGS
CCCCHHHHHHHCCCCEECCCCEEEECCCCCEEEEHHHHHHHHHHHHHHHCHHHHHHCCCC
GAYGTFTVTKDITKYTKAKIFSKVGKKTECFFRFSTVAGERGFADAVRDPRGFAMKYYTE
CCEEEEEEHHHHHHHHHHHHHHHHCCCCEEEEEEEHHCCCCCCHHHHCCCCCCEEEEEEC
EGNWDLVGNNTPIFFIRDPIKFPDFIHTQKRDPQTNLHSPTMVWDFWSNVPESLHQVTWV
CCCEEEECCCCCEEEEECCCCCCHHHHCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHH
MGDRGIPKTYRHMDGFGSHTFSLINAKDERVWVKFHFKCMQGLAHLTNEEAAEIRKNDPD
HCCCCCCHHHHHHCCCCCCEEEEEECCCCEEEEEEHHHHHHHHHHHCCHHHHHHHCCCCC
SHQRDLYDAIARGDFPKWKMCIQVMPEEDAKKYRFHPFDVTKVWSQKDYPLMEVGIVELN
HHHHHHHHHHHCCCCCCHHHHEEECCCCCCHHCCCCCCCHHHHCCCCCCCEEEEEEEEEC
KNPENYFAEVEQAAFTPANVVPGIGYSPDRMLQGRLFSYGDTHRYRLGVNYAQIPVNKPR
CCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCHHHCCCCCEEEEECCCEEECCCCCCC
CPFHSSSRDGHMQNGYYGALQNYTPSSLPGYKEDKSARDPKLNLTHIEKEYEVWNWDFRA
CCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEECCCCEEEECEECC
DDSDYYTQPGDLYRLMKPDEKERLYDTIGGSLAHVEHKEIVDKQLEHFRKADPKYAEGVK
CCCCCCCCCCCEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
KALEKHQKMMKDMHMKDMSHTKKKK
HHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MVNKDLKQTTAFGAPVWDDNNVVTVGPRGPVLLQSTWFLEKLAAFDRERIPERVVHAKGS
CCCCHHHHHHHCCCCEECCCCEEEECCCCCEEEEHHHHHHHHHHHHHHHCHHHHHHCCCC
GAYGTFTVTKDITKYTKAKIFSKVGKKTECFFRFSTVAGERGFADAVRDPRGFAMKYYTE
CCEEEEEEHHHHHHHHHHHHHHHHCCCCEEEEEEEHHCCCCCCHHHHCCCCCCEEEEEEC
EGNWDLVGNNTPIFFIRDPIKFPDFIHTQKRDPQTNLHSPTMVWDFWSNVPESLHQVTWV
CCCEEEECCCCCEEEEECCCCCCHHHHCCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHH
MGDRGIPKTYRHMDGFGSHTFSLINAKDERVWVKFHFKCMQGLAHLTNEEAAEIRKNDPD
HCCCCCCHHHHHHCCCCCCEEEEEECCCCEEEEEEHHHHHHHHHHHCCHHHHHHHCCCCC
SHQRDLYDAIARGDFPKWKMCIQVMPEEDAKKYRFHPFDVTKVWSQKDYPLMEVGIVELN
HHHHHHHHHHHCCCCCCHHHHEEECCCCCCHHCCCCCCCHHHHCCCCCCCEEEEEEEEEC
KNPENYFAEVEQAAFTPANVVPGIGYSPDRMLQGRLFSYGDTHRYRLGVNYAQIPVNKPR
CCHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHCHHHCCCCCEEEEECCCEEECCCCCCC
CPFHSSSRDGHMQNGYYGALQNYTPSSLPGYKEDKSARDPKLNLTHIEKEYEVWNWDFRA
CCCCCCCCCCCCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCCCEEECCCCEEEECEECC
DDSDYYTQPGDLYRLMKPDEKERLYDTIGGSLAHVEHKEIVDKQLEHFRKADPKYAEGVK
CCCCCCCCCCCEEECCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHH
KALEKHQKMMKDMHMKDMSHTKKKK
HHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]