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The map label for this gene is trpD

Identifier: 109946655

GI number: 109946655

Start: 19867

End: 20874

Strand: Reverse

Name: trpD

Synonym: Hac_0016

Alternate gene names: 109946655

Gene position: 20874-19867 (Counterclockwise)

Preceding gene: 109946656

Following gene: 162139481

Centisome position: 1.34

GC content: 40.08

Gene sequence:

>1008_bases
ATGAAAGGGATTTTAAACGCCTTGTACCATCAAAAAGACTTGAATGATGAAGAAGTCAAAAGATTATTCACTTTTATTAT
TAACGAAGAAGTAAGCCCCACGCAACTTGGGGCGATTTTGTGTGCTTTAAAGATTAAGGGCGAGAGCTTGAGTGAGATTA
GCGCCGCTGCAACCACGCTTTTAGAGCATGCCCCTAAACCTTTTAAGAGCGGATTGGATTTAATAGACAATTGCGGCACG
GGGGGTGATGGGCTAAAAACGATTAATATTAGCACTATTGCTGCACTCATTGCCAGCTCTATGGGATTACCGATGGCTAA
ACATGGATCAAGAAGCGTGTCCAGTCATAGCGGGAGCGCGGATTTATTGGAAAATCTAGGCGTGAATATTGAAATGAATC
GCGCGCAATTAGAAAATTGCCTCAAAGAATCGCATTTTGGGTTTTTATTCGCGCCTTTATACCACCAAAGTTTTAAAAAA
TCTGCCCCTTTAAGAAAAGAGCTTTTCACTAAAACGATTTTTAATTGTTTAGGGCCTTTAATCAACCCTTTAAGACCCAC
AATCCAGCTTTTAGGCGTGTATGATGAATCCTTGTGCAAGACTATGGTGCTAGCATTAAAGGCTTTAGGCGTTAAAAGGG
CGATGGTGGTTAATGGAGGAGGGACAGATGAAATCGTGTTGCATGCTATTACGCATGCGTGTGAATTAAAAAATAACGAG
ATTTTAGAGTATGACTTGAGCGCTAAAGATTTTAATTTACCCCCCTATGATTTGAAAGAATTACAGATTGAAAGCGTGCA
AGAAAGCGTTCAAGCGTGTTTGGATATTTTAGAAAATAAGGGCAAGGATTCGCACACGATGGTGGTTGTGGCGAATGTGG
CGAGTTTGTTGTATTTGAGTAATAGAGCTAAAGATTTAAAAGAGGGCGTGAGCATGACTTTAGAGCATTTAAAAACCAAA
GCGCCTTATACGCATTTACAAAAAATCATAAGATTAAGCCATGCCTAG

Upstream 100 bases:

>100_bases
ATAGAATCTTAGCCTATCAATTCCACCCTGAAAGCATCATGACTTTACAAGGGAGGGCGTTACTGGAACAAAGCGTGGGG
TTTTTAAAAGGGCTATCATC

Downstream 100 bases:

>100_bases
CGTGTTAGAGAATATCCTTAAAGACAAACTCTTAGAAGTCTCTGCACTTAAAAAAAATTACACCTTGCCCGCAAACATAA
GCCCAAGCGATAGGGATTTT

Product: anthranilate phosphoribosyltransferase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MKGILNALYHQKDLNDEEVKRLFTFIINEEVSPTQLGAILCALKIKGESLSEISAAATTLLEHAPKPFKSGLDLIDNCGT
GGDGLKTINISTIAALIASSMGLPMAKHGSRSVSSHSGSADLLENLGVNIEMNRAQLENCLKESHFGFLFAPLYHQSFKK
SAPLRKELFTKTIFNCLGPLINPLRPTIQLLGVYDESLCKTMVLALKALGVKRAMVVNGGGTDEIVLHAITHACELKNNE
ILEYDLSAKDFNLPPYDLKELQIESVQESVQACLDILENKGKDSHTMVVVANVASLLYLSNRAKDLKEGVSMTLEHLKTK
APYTHLQKIIRLSHA

Sequences:

>Translated_335_residues
MKGILNALYHQKDLNDEEVKRLFTFIINEEVSPTQLGAILCALKIKGESLSEISAAATTLLEHAPKPFKSGLDLIDNCGT
GGDGLKTINISTIAALIASSMGLPMAKHGSRSVSSHSGSADLLENLGVNIEMNRAQLENCLKESHFGFLFAPLYHQSFKK
SAPLRKELFTKTIFNCLGPLINPLRPTIQLLGVYDESLCKTMVLALKALGVKRAMVVNGGGTDEIVLHAITHACELKNNE
ILEYDLSAKDFNLPPYDLKELQIESVQESVQACLDILENKGKDSHTMVVVANVASLLYLSNRAKDLKEGVSMTLEHLKTK
APYTHLQKIIRLSHA
>Mature_335_residues
MKGILNALYHQKDLNDEEVKRLFTFIINEEVSPTQLGAILCALKIKGESLSEISAAATTLLEHAPKPFKSGLDLIDNCGT
GGDGLKTINISTIAALIASSMGLPMAKHGSRSVSSHSGSADLLENLGVNIEMNRAQLENCLKESHFGFLFAPLYHQSFKK
SAPLRKELFTKTIFNCLGPLINPLRPTIQLLGVYDESLCKTMVLALKALGVKRAMVVNGGGTDEIVLHAITHACELKNNE
ILEYDLSAKDFNLPPYDLKELQIESVQESVQACLDILENKGKDSHTMVVVANVASLLYLSNRAKDLKEGVSMTLEHLKTK
APYTHLQKIIRLSHA

Specific function: Tryptophan biosynthesis; first step. Tryptophan biosynthesis; second step. [C]

COG id: COG0547

COG function: function code E; Anthranilate phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anthranilate phosphoribosyltransferase family

Homologues:

Organism=Escherichia coli, GI1787517, Length=324, Percent_Identity=43.2098765432099, Blast_Score=229, Evalue=2e-61,
Organism=Saccharomyces cerevisiae, GI6320561, Length=310, Percent_Identity=30, Blast_Score=104, Evalue=2e-23,

Paralogues:

None

Copy number: 945 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 900 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): TRPD_HELAH (Q17ZP2)

Other databases:

- EMBL:   AM260522
- RefSeq:   YP_663883.1
- ProteinModelPortal:   Q17ZP2
- SMR:   Q17ZP2
- STRING:   Q17ZP2
- GeneID:   4176666
- GenomeReviews:   AM260522_GR
- KEGG:   hac:Hac_0016
- NMPDR:   fig|382638.8.peg.16
- eggNOG:   COG0547
- HOGENOM:   HBG559996
- OMA:   HGNKSAS
- PhylomeDB:   Q17ZP2
- ProtClustDB:   PRK00188
- BioCyc:   HACI382638:HAC_0016-MONOMER
- HAMAP:   MF_00211
- InterPro:   IPR005940
- InterPro:   IPR000312
- InterPro:   IPR017459
- InterPro:   IPR020072
- Gene3D:   G3DSA:1.20.970.10
- Gene3D:   G3DSA:3.40.1030.10
- TIGRFAMs:   TIGR01245

Pfam domain/function: PF02885 Glycos_trans_3N; PF00591 Glycos_transf_3; SSF47648 Glyco_trans_3; SSF52418 Glyco_trans_3

EC number: =2.4.2.18

Molecular weight: Translated: 36646; Mature: 36646

Theoretical pI: Translated: 7.13; Mature: 7.13

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKGILNALYHQKDLNDEEVKRLFTFIINEEVSPTQLGAILCALKIKGESLSEISAAATTL
CCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHEECCCCHHHHHHHHHHH
LEHAPKPFKSGLDLIDNCGTGGDGLKTINISTIAALIASSMGLPMAKHGSRSVSSHSGSA
HHHCCCHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHCCCCCHHCCCCCCCCCCCCH
DLLENLGVNIEMNRAQLENCLKESHFGFLFAPLYHQSFKKSAPLRKELFTKTIFNCLGPL
HHHHHCCCCEEECHHHHHHHHHHCCCCEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
INPLRPTIQLLGVYDESLCKTMVLALKALGVKRAMVVNGGGTDEIVLHAITHACELKNNE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHCCCCC
ILEYDLSAKDFNLPPYDLKELQIESVQESVQACLDILENKGKDSHTMVVVANVASLLYLS
EEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHH
NRAKDLKEGVSMTLEHLKTKAPYTHLQKIIRLSHA
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCC
>Mature Secondary Structure
MKGILNALYHQKDLNDEEVKRLFTFIINEEVSPTQLGAILCALKIKGESLSEISAAATTL
CCHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHEECCCCHHHHHHHHHHH
LEHAPKPFKSGLDLIDNCGTGGDGLKTINISTIAALIASSMGLPMAKHGSRSVSSHSGSA
HHHCCCHHHHHHHHHHCCCCCCCCEEEEHHHHHHHHHHHHCCCCCHHCCCCCCCCCCCCH
DLLENLGVNIEMNRAQLENCLKESHFGFLFAPLYHQSFKKSAPLRKELFTKTIFNCLGPL
HHHHHCCCCEEECHHHHHHHHHHCCCCEEEHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
INPLRPTIQLLGVYDESLCKTMVLALKALGVKRAMVVNGGGTDEIVLHAITHACELKNNE
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHCCCCC
ILEYDLSAKDFNLPPYDLKELQIESVQESVQACLDILENKGKDSHTMVVVANVASLLYLS
EEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEHHHHHHHHHHH
NRAKDLKEGVSMTLEHLKTKAPYTHLQKIIRLSHA
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA