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The map label for this gene is fadJ [H]

Identifier: 110681106

GI number: 110681106

Start: 3830600

End: 3832798

Strand: Direct

Name: fadJ [H]

Synonym: RD1_3973

Alternate gene names: 110681106

Gene position: 3830600-3832798 (Clockwise)

Preceding gene: 110681105

Following gene: 110681107

Centisome position: 92.68

GC content: 58.8

Gene sequence:

>2199_bases
ATGACTGATTTTACAATGGACACCGATGGACAAGGCATCGCGACGATCACATGGGATGTGAAAGACAAATCCATGAATGT
GATGACCCTTGAGGCATGGGATGTACTGGACGGGCTGATCGACGCTGCACTGGGCGATGAGGCCGTGAAAGGCGTGATCA
TCACCTCGGGCAAGGACAGCTTTGCAGGTGGGATGGACCTCAACGTGATTGCCCGCATGAAAGAGATGGCAGGCGATGAC
CCGGCAAAAGGTTTGTTTGACGGGATCATGAACGCCCATCGCATCATGCGCAAAATCGAACGCGCGGGCATGGACCCCAA
GACGCTGAAAGGTGGCAAGCCCATTGCAACTGTACTGCCCGGTACGGCCCTTGGCATCGGGCTTGAAATTCCGCTGTGCA
CGCATCGCATCTTTGCCGCACCCAATCCCAAGGCCAAGATCGGCCTGCCCGAGATCATGGTCGGTATCTTTCCCGGTGCC
GGGGGCACGACCCGCCTGACGCGCAAGATGGGGGCGATGGCCGCATCGCCGTTCCTGCTGGAAGGCAAACTGGTTGACCC
CGCGCGCGCCAAGGCCGCCGGGTTGATCGACGAAGTGGCCGATGATCCGATGGCCGCTGCCCGCGACTGGGTGTTGAATG
CAAAGGACGCGGACCTCGTCAAACCGTGGGATGCCAAGGGTTATAAAATGCCCGGCGGTGCGCCCTATCATCCGGCGGGT
TTCATGACCTTCGTCGGTGCATCTGCGATGGTGAACGGCAAGACCCAAGGGGTGTATCCGGCGGCCAAGGCGTTGTTGTC
AGCTGTCTATGAGGGCGCGCTTGTGCCTTTTGACACCGCCCTCAAGGTTGAAGCGCGCTGGTTCACGAATGTGCTCATGA
ATCCGTCATCATCCGCGATGATCCGCTCGCTTTTCGTCAACAAGGAAGCGCTGGAGAAAGGCGCGGTGCGCCCGAATGAT
GTCGCAGACCAACGCGTCAAAAAGCTCGGCGTGCTGGGCGCGGGCATGATGGGGGCTGGTATCTCGCTGGTCTCCGCGCA
GGCCGGGATCGAGGTTGTGCTGATTGACCAGACGCAAGAGGCCGCAGATCGTGGCAAGGCCTATACCGCCAGCTTTGCTG
ACAAAGGCATTGCGCGCAAAAAGACAACGCCTGAAAAGAAAGAACAACTGCTCAACCTGATCACGGCGACCACTGAGCTT
GAACACCTCAAAGACTGTGATCTGATCATCGAGGCGGTGTTCGAGGACCCGAAAGTCAAGGCCGAAATGACCCGGAAGGT
CGAAGCCGTGATCCCGCAGGATTGTGTCTTCGCCTCCAACACCTCTACCCTGCCAATCACCGAACTGGCCAAAGCCTCGT
CGCGCCCGGATCAGTTCATCGGCATCCACTTCTTCTCGCCCGTCGAGAAAATGCTGCTGGTGGAGATTATCAAGGGCAAG
GGTACGGGCGACCGGGCTGTAGCCAAGGCGCTGGATTACGTGCGCCAGATTCGCAAAACGCCCATCGTTGTGAATGACGC
GCGGTTCTTTTATGCCAACCGCTGCATCATTCCCTACATCAACGAAGGCATCCGCATGGTTGCCGAGGGTGTTGAACCCG
CGCTGATCGAAAACGCGGCCAAACTGGTCGGTATGCCACTTGGCCCGCTGCAACTGGTGGATGAAACCTCGATTGATCTG
GGCGCCAAAATCGCGCGTGCCACCAAGGCCGCCATGGGCGATGCCTATCCCGATGCGGCGGTGGATGAGGTAATCTTCTG
GATGGAAGGTGAAAACCGTCTGGGCCGCAAGACCAGTGCCGGGTTTTACGCCTATGACGAAAAGGGCAAACGTCAGGATC
TTTGGGACGGTCTTGCCGTGCAATATCCTGTTTCAGATACACAGCCCGATCTGATTGACGTGCAGCACCGCCTGTTGTTT
TCGCAAACGCTCGAAGCGGTGCGCGCGCTCGAAGAAGGCGTGTTGATGGACATCCGCGAAGGGGACGTCGGCGCGATTTT
GGGCTGGGGCTTTGCACCATGGTCCGGCGGACCGCTCAGCTGGCTCGACATGCTGGGCGCGGCCTATGCGGCTGAGCGCT
GCGATCAGCTGACGCAAAGCTTCGGGGAGCGTTTCGCCTGCCCCGATCTGCTGCGCGAGATGGCTACCAAGAACCAGAAT
TTTTACAGCCGGTTCGTCCAAAAGCCCAAAGCCGCCTGA

Upstream 100 bases:

>100_bases
AGGTCGGTCTGGCTACGCTCTGCATCGCCTCCGGCATGGGTGCCGCGACCATCATCGAGCGCGTTTAACCGCCGAAACCC
CGGAAAAAGGGAAACGAGAC

Downstream 100 bases:

>100_bases
CGCGCGCCGCCCGTCAGAACCAGAAAGGGGGCAGATCGCCCCCTTTTTCATGCGCCATGGCAGTGTCGCCGCCACATGAA
AAACCGCACTTGCCCCATCG

Product: fatty acid oxidation complex alpha subunit, putative

Products: NA

Alternate protein names: Enoyl-CoA hydratase/3-hydroxybutyryl-CoA epimerase; 3-hydroxyacyl-CoA dehydrogenase [H]

Number of amino acids: Translated: 732; Mature: 731

Protein sequence:

>732_residues
MTDFTMDTDGQGIATITWDVKDKSMNVMTLEAWDVLDGLIDAALGDEAVKGVIITSGKDSFAGGMDLNVIARMKEMAGDD
PAKGLFDGIMNAHRIMRKIERAGMDPKTLKGGKPIATVLPGTALGIGLEIPLCTHRIFAAPNPKAKIGLPEIMVGIFPGA
GGTTRLTRKMGAMAASPFLLEGKLVDPARAKAAGLIDEVADDPMAAARDWVLNAKDADLVKPWDAKGYKMPGGAPYHPAG
FMTFVGASAMVNGKTQGVYPAAKALLSAVYEGALVPFDTALKVEARWFTNVLMNPSSSAMIRSLFVNKEALEKGAVRPND
VADQRVKKLGVLGAGMMGAGISLVSAQAGIEVVLIDQTQEAADRGKAYTASFADKGIARKKTTPEKKEQLLNLITATTEL
EHLKDCDLIIEAVFEDPKVKAEMTRKVEAVIPQDCVFASNTSTLPITELAKASSRPDQFIGIHFFSPVEKMLLVEIIKGK
GTGDRAVAKALDYVRQIRKTPIVVNDARFFYANRCIIPYINEGIRMVAEGVEPALIENAAKLVGMPLGPLQLVDETSIDL
GAKIARATKAAMGDAYPDAAVDEVIFWMEGENRLGRKTSAGFYAYDEKGKRQDLWDGLAVQYPVSDTQPDLIDVQHRLLF
SQTLEAVRALEEGVLMDIREGDVGAILGWGFAPWSGGPLSWLDMLGAAYAAERCDQLTQSFGERFACPDLLREMATKNQN
FYSRFVQKPKAA

Sequences:

>Translated_732_residues
MTDFTMDTDGQGIATITWDVKDKSMNVMTLEAWDVLDGLIDAALGDEAVKGVIITSGKDSFAGGMDLNVIARMKEMAGDD
PAKGLFDGIMNAHRIMRKIERAGMDPKTLKGGKPIATVLPGTALGIGLEIPLCTHRIFAAPNPKAKIGLPEIMVGIFPGA
GGTTRLTRKMGAMAASPFLLEGKLVDPARAKAAGLIDEVADDPMAAARDWVLNAKDADLVKPWDAKGYKMPGGAPYHPAG
FMTFVGASAMVNGKTQGVYPAAKALLSAVYEGALVPFDTALKVEARWFTNVLMNPSSSAMIRSLFVNKEALEKGAVRPND
VADQRVKKLGVLGAGMMGAGISLVSAQAGIEVVLIDQTQEAADRGKAYTASFADKGIARKKTTPEKKEQLLNLITATTEL
EHLKDCDLIIEAVFEDPKVKAEMTRKVEAVIPQDCVFASNTSTLPITELAKASSRPDQFIGIHFFSPVEKMLLVEIIKGK
GTGDRAVAKALDYVRQIRKTPIVVNDARFFYANRCIIPYINEGIRMVAEGVEPALIENAAKLVGMPLGPLQLVDETSIDL
GAKIARATKAAMGDAYPDAAVDEVIFWMEGENRLGRKTSAGFYAYDEKGKRQDLWDGLAVQYPVSDTQPDLIDVQHRLLF
SQTLEAVRALEEGVLMDIREGDVGAILGWGFAPWSGGPLSWLDMLGAAYAAERCDQLTQSFGERFACPDLLREMATKNQN
FYSRFVQKPKAA
>Mature_731_residues
TDFTMDTDGQGIATITWDVKDKSMNVMTLEAWDVLDGLIDAALGDEAVKGVIITSGKDSFAGGMDLNVIARMKEMAGDDP
AKGLFDGIMNAHRIMRKIERAGMDPKTLKGGKPIATVLPGTALGIGLEIPLCTHRIFAAPNPKAKIGLPEIMVGIFPGAG
GTTRLTRKMGAMAASPFLLEGKLVDPARAKAAGLIDEVADDPMAAARDWVLNAKDADLVKPWDAKGYKMPGGAPYHPAGF
MTFVGASAMVNGKTQGVYPAAKALLSAVYEGALVPFDTALKVEARWFTNVLMNPSSSAMIRSLFVNKEALEKGAVRPNDV
ADQRVKKLGVLGAGMMGAGISLVSAQAGIEVVLIDQTQEAADRGKAYTASFADKGIARKKTTPEKKEQLLNLITATTELE
HLKDCDLIIEAVFEDPKVKAEMTRKVEAVIPQDCVFASNTSTLPITELAKASSRPDQFIGIHFFSPVEKMLLVEIIKGKG
TGDRAVAKALDYVRQIRKTPIVVNDARFFYANRCIIPYINEGIRMVAEGVEPALIENAAKLVGMPLGPLQLVDETSIDLG
AKIARATKAAMGDAYPDAAVDEVIFWMEGENRLGRKTSAGFYAYDEKGKRQDLWDGLAVQYPVSDTQPDLIDVQHRLLFS
QTLEAVRALEEGVLMDIREGDVGAILGWGFAPWSGGPLSWLDMLGAAYAAERCDQLTQSFGERFACPDLLREMATKNQNF
YSRFVQKPKAA

Specific function: Catalyzes the formation of an hydroxyacyl-CoA by addition of water on enoyl-CoA. Also exhibits 3-hydroxyacyl-CoA epimerase and 3-hydroxyacyl-CoA dehydrogenase activities [H]

COG id: COG1250

COG function: function code I; 3-hydroxyacyl-CoA dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the central section; belongs to the 3-hydroxyacyl- CoA dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI20127408, Length=741, Percent_Identity=31.4439946018893, Blast_Score=343, Evalue=4e-94,
Organism=Homo sapiens, GI68989263, Length=719, Percent_Identity=25.5910987482615, Blast_Score=206, Evalue=7e-53,
Organism=Homo sapiens, GI261878539, Length=630, Percent_Identity=26.5079365079365, Blast_Score=192, Evalue=7e-49,
Organism=Homo sapiens, GI296179429, Length=292, Percent_Identity=34.5890410958904, Blast_Score=164, Evalue=4e-40,
Organism=Homo sapiens, GI296179427, Length=309, Percent_Identity=33.0097087378641, Blast_Score=156, Evalue=7e-38,
Organism=Homo sapiens, GI194097323, Length=180, Percent_Identity=28.3333333333333, Blast_Score=69, Evalue=2e-11,
Organism=Escherichia coli, GI1788682, Length=727, Percent_Identity=33.837689133425, Blast_Score=350, Evalue=1e-97,
Organism=Escherichia coli, GI1790281, Length=689, Percent_Identity=31.3497822931785, Blast_Score=269, Evalue=5e-73,
Organism=Escherichia coli, GI1787661, Length=296, Percent_Identity=30.0675675675676, Blast_Score=126, Evalue=5e-30,
Organism=Escherichia coli, GI1787659, Length=160, Percent_Identity=35.625, Blast_Score=82, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI17558304, Length=756, Percent_Identity=29.8941798941799, Blast_Score=307, Evalue=1e-83,
Organism=Caenorhabditis elegans, GI17508951, Length=757, Percent_Identity=29.7225891677675, Blast_Score=291, Evalue=7e-79,
Organism=Caenorhabditis elegans, GI17508953, Length=757, Percent_Identity=29.7225891677675, Blast_Score=291, Evalue=9e-79,
Organism=Caenorhabditis elegans, GI25144276, Length=636, Percent_Identity=29.874213836478, Blast_Score=247, Evalue=1e-65,
Organism=Caenorhabditis elegans, GI71985923, Length=381, Percent_Identity=29.9212598425197, Blast_Score=185, Evalue=9e-47,
Organism=Caenorhabditis elegans, GI71985930, Length=395, Percent_Identity=28.6075949367089, Blast_Score=174, Evalue=2e-43,
Organism=Caenorhabditis elegans, GI17553560, Length=297, Percent_Identity=31.6498316498317, Blast_Score=140, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17563036, Length=291, Percent_Identity=29.8969072164948, Blast_Score=135, Evalue=1e-31,
Organism=Caenorhabditis elegans, GI17549919, Length=298, Percent_Identity=29.8657718120805, Blast_Score=131, Evalue=1e-30,
Organism=Caenorhabditis elegans, GI17554946, Length=191, Percent_Identity=26.7015706806283, Blast_Score=66, Evalue=7e-11,
Organism=Drosophila melanogaster, GI24583077, Length=741, Percent_Identity=31.3090418353576, Blast_Score=301, Evalue=1e-81,
Organism=Drosophila melanogaster, GI24583079, Length=741, Percent_Identity=31.3090418353576, Blast_Score=301, Evalue=1e-81,
Organism=Drosophila melanogaster, GI19921000, Length=741, Percent_Identity=31.3090418353576, Blast_Score=300, Evalue=2e-81,
Organism=Drosophila melanogaster, GI20129971, Length=191, Percent_Identity=28.2722513089005, Blast_Score=75, Evalue=1e-13,
Organism=Drosophila melanogaster, GI24653477, Length=191, Percent_Identity=28.2722513089005, Blast_Score=75, Evalue=1e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006180
- InterPro:   IPR006176
- InterPro:   IPR006108
- InterPro:   IPR008927
- InterPro:   IPR001753
- InterPro:   IPR013328
- InterPro:   IPR012802
- InterPro:   IPR016040 [H]

Pfam domain/function: PF00725 3HCDH; PF02737 3HCDH_N; PF00378 ECH [H]

EC number: =4.2.1.17; =5.1.2.3; =1.1.1.35 [H]

Molecular weight: Translated: 78966; Mature: 78835

Theoretical pI: Translated: 5.42; Mature: 5.42

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDFTMDTDGQGIATITWDVKDKSMNVMTLEAWDVLDGLIDAALGDEAVKGVIITSGKDS
CCCCCCCCCCCEEEEEEEEECCCCCCEEEEHHHHHHHHHHHHHHCHHHHCEEEEECCCCC
FAGGMDLNVIARMKEMAGDDPAKGLFDGIMNAHRIMRKIERAGMDPKTLKGGKPIATVLP
CCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECC
GTALGIGLEIPLCTHRIFAAPNPKAKIGLPEIMVGIFPGAGGTTRLTRKMGAMAASPFLL
CCCCCCEEECCHHHHEEEECCCCCCCCCCHHEEEEEECCCCCHHHHHHHHHHHHCCCEEE
EGKLVDPARAKAAGLIDEVADDPMAAARDWVLNAKDADLVKPWDAKGYKMPGGAPYHPAG
ECCCCCHHHHHHHHHHHHHCCCHHHHHHHHEECCCCCCCCCCCCCCCEECCCCCCCCCCH
FMTFVGASAMVNGKTQGVYPAAKALLSAVYEGALVPFDTALKVEARWFTNVLMNPSSSAM
HHHHHCCHHEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHCCCCHHHH
IRSLFVNKEALEKGAVRPNDVADQRVKKLGVLGAGMMGAGISLVSAQAGIEVVLIDQTQE
HHHHHHCHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHCCHHEEECCCCEEEEEECCCHH
AADRGKAYTASFADKGIARKKTTPEKKEQLLNLITATTELEHLKDCDLIIEAVFEDPKVK
HHHCCCEEEEHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
AEMTRKVEAVIPQDCVFASNTSTLPITELAKASSRPDQFIGIHFFSPVEKMLLVEIIKGK
HHHHHHHHHHCCCCEEEECCCCCCCHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHCC
GTGDRAVAKALDYVRQIRKTPIVVNDARFFYANRCIIPYINEGIRMVAEGVEPALIENAA
CCCHHHHHHHHHHHHHHHCCCEEEECCEEEEECCEEEHHHHHHHHHHHHCCCHHHHHHHH
KLVGMPLGPLQLVDETSIDLGAKIARATKAAMGDAYPDAAVDEVIFWMEGENRLGRKTSA
HHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHEEEEECCCCCCCCCCCC
GFYAYDEKGKRQDLWDGLAVQYPVSDTQPDLIDVQHRLLFSQTLEAVRALEEGVLMDIRE
CEEEECCCCCHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECC
GDVGAILGWGFAPWSGGPLSWLDMLGAAYAAERCDQLTQSFGERFACPDLLREMATKNQN
CCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHH
FYSRFVQKPKAA
HHHHHHHCCCCC
>Mature Secondary Structure 
TDFTMDTDGQGIATITWDVKDKSMNVMTLEAWDVLDGLIDAALGDEAVKGVIITSGKDS
CCCCCCCCCCEEEEEEEEECCCCCCEEEEHHHHHHHHHHHHHHCHHHHCEEEEECCCCC
FAGGMDLNVIARMKEMAGDDPAKGLFDGIMNAHRIMRKIERAGMDPKTLKGGKPIATVLP
CCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEECC
GTALGIGLEIPLCTHRIFAAPNPKAKIGLPEIMVGIFPGAGGTTRLTRKMGAMAASPFLL
CCCCCCEEECCHHHHEEEECCCCCCCCCCHHEEEEEECCCCCHHHHHHHHHHHHCCCEEE
EGKLVDPARAKAAGLIDEVADDPMAAARDWVLNAKDADLVKPWDAKGYKMPGGAPYHPAG
ECCCCCHHHHHHHHHHHHHCCCHHHHHHHHEECCCCCCCCCCCCCCCEECCCCCCCCCCH
FMTFVGASAMVNGKTQGVYPAAKALLSAVYEGALVPFDTALKVEARWFTNVLMNPSSSAM
HHHHHCCHHEECCCCCCCCHHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHCCCCHHHH
IRSLFVNKEALEKGAVRPNDVADQRVKKLGVLGAGMMGAGISLVSAQAGIEVVLIDQTQE
HHHHHHCHHHHHHCCCCCCHHHHHHHHHHHHHCCCHHHCCHHEEECCCCEEEEEECCCHH
AADRGKAYTASFADKGIARKKTTPEKKEQLLNLITATTELEHLKDCDLIIEAVFEDPKVK
HHHCCCEEEEHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
AEMTRKVEAVIPQDCVFASNTSTLPITELAKASSRPDQFIGIHFFSPVEKMLLVEIIKGK
HHHHHHHHHHCCCCEEEECCCCCCCHHHHHHCCCCCCCEEEEEHHHHHHHHHHHHHHHCC
GTGDRAVAKALDYVRQIRKTPIVVNDARFFYANRCIIPYINEGIRMVAEGVEPALIENAA
CCCHHHHHHHHHHHHHHHCCCEEEECCEEEEECCEEEHHHHHHHHHHHHCCCHHHHHHHH
KLVGMPLGPLQLVDETSIDLGAKIARATKAAMGDAYPDAAVDEVIFWMEGENRLGRKTSA
HHHCCCCCCHHHHCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHEEEEECCCCCCCCCCCC
GFYAYDEKGKRQDLWDGLAVQYPVSDTQPDLIDVQHRLLFSQTLEAVRALEEGVLMDIRE
CEEEECCCCCHHHHHCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEECC
GDVGAILGWGFAPWSGGPLSWLDMLGAAYAAERCDQLTQSFGERFACPDLLREMATKNQN
CCCCEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHH
FYSRFVQKPKAA
HHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA