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The map label for this gene is dhaK [H]

Identifier: 110680853

GI number: 110680853

Start: 3570519

End: 3572144

Strand: Direct

Name: dhaK [H]

Synonym: RD1_3702

Alternate gene names: 110680853

Gene position: 3570519-3572144 (Clockwise)

Preceding gene: 110680852

Following gene: 110680854

Centisome position: 86.39

GC content: 62.79

Gene sequence:

>1626_bases
ATGACGCAGTTCATCAATAAAAAGGAAACGCTGGTCACCGATGCGATTGACGGGCTGTTGGCCAGTGCTGGCGGGTCGCT
GCGGCGTCTGGACGGCTATCCGCATATCAAGGTCGTCTGCCGTGCCGATTGGGATAAATCGCAGGTTGCCTTGATTTCAG
GCGGCGGTTCAGGCCACGAACCCGCGCACGCCGGGTTCGTCGGGCGCGGTATGTTGACGGCAGCTGTTTGCGGTGAGGTT
TTCGCCTCGCCATCGGTGGACGCGGTGCTTGCCGCACTTCTGGCCGTGACCGGGCCTGCGGGATGTCTTTTGATCGTGAA
GAACTACACGGGCGACCGGCTCAATTTCGGGCTGGCAGCAGAGCGCGCCCGCGCGCTTGGCCTCAAGGTTTCCATGGTCG
TTGTCGGTGATGATATCGCGCTGCCGGATCTGCCGCAGCCGCGCGGTGTCGCGGGCACGTTGTTTGTCCACAAAATCGCC
GGAGCCATGGCGGAACAAGGGGCCCCCCTTGAGGATATCTGCAAGGCTGCACAAAACGCCATCGAAAGAATGGCCACGAT
TGGCATGTCACTCGACACCTGTACGGTTCCCGGCGCGCAGAAAGAAGACCGCATCGCAACGGGTATGGCAGAACTTGGCC
TCGGCATTCACGGTGAGCCCGGTGTGCAGCAGGTTGCCTTTGGAGACGCGCGAAACGCCATGGATATGGTGCTTGATAAA
CTCGCCCCAAGGATCGGTGAAGAACCTCACGTTGCCATCCTGAACAACCTGGGTGCCACCACACCGCTGGAGATGAGTGT
CCTGACCCACGTGCTGACAACCTCGGCCAAGGCGAAAAACATCAAGCATATCATCGGCCCGGCGCCGCTGATGACATCGC
TGGACATGCATGGGTTTTCCCTGTCCGTCCTGCCGGTCGATGAGACGATCCTGCCCCATCTGGGTTATCGCGTGGACATG
CCCGCCTGGCCCGGCATGCAGACCATCAGCGCGCCCGCCGTCATCGCATTGCCCGATGGGTTGAGCCCGGTTCAGCCCAC
GGCCTCGGACAATGACCAAACCCGCCGACTGGTCGCGCATGCCTGCGATCTGCTGATCGCCAGCGAAGCGGAGTTGAACG
CGCTGGATGCGAAATCAGGCGATGGTGACACGGGCAGCACATTGGCCACTGCTGCGCGCGATCTCAAAGGGGCGCTGGAC
CGTCTGCCGCTGGCGGATCCGGCACAGTTGTTCCGTGCCCTCAGCAATGAACTCAGCCAGACCATGGGCGGGTCCTCCGG
CGTGATCCTTGCCATTTTCTTCGGGGCGGCAGGCGATGCGGCGGCCAAGGGTCTGCCACCCGCCAAAGCGCTTGTCTCGG
GCTTGGAACGGATCAGCGAAGTGGGCGGCGCAACAAAGGGCGACCGCACGATGATCGACGCGCTGGAGCCTGCCTTGCAC
GCCCTGAACGAAGGCATCGCAGCGGCAGCCACGGCAGCGCGCAAAGGGGCCAGCGAGACCGCAAGCATCGGGCAGGCCAA
AGCGGGCCGCGCCTCCTACGTGCCAGAGGAAAACCTGATCGGGCACAATGATCCGGGTGCCGAAGCCGTGGCACGGTTGT
TCGAGGGTCTGGCAACCCTCGCCTGA

Upstream 100 bases:

>100_bases
TTCACAGGAACACTGTCGCAAACAAGACCGCGAACACGTTTGGGCGGATGTCCAGCGCACAGCGCACCGTCAGCCAGTTG
CATAAGAGGAATAGACACGC

Downstream 100 bases:

>100_bases
GCATGCAATGAATTTGGACAAGATCGATGCGGCTCACTCGAAACAGCGGCAAGGCGGCGGGGTAGCCCCGCGCATCTGAC
ACCAAAAAACCGCGCAAAGC

Product: dihydroxyacetone kinase

Products: NA

Alternate protein names: DHA kinase; Glycerone kinase [H]

Number of amino acids: Translated: 541; Mature: 540

Protein sequence:

>541_residues
MTQFINKKETLVTDAIDGLLASAGGSLRRLDGYPHIKVVCRADWDKSQVALISGGGSGHEPAHAGFVGRGMLTAAVCGEV
FASPSVDAVLAALLAVTGPAGCLLIVKNYTGDRLNFGLAAERARALGLKVSMVVVGDDIALPDLPQPRGVAGTLFVHKIA
GAMAEQGAPLEDICKAAQNAIERMATIGMSLDTCTVPGAQKEDRIATGMAELGLGIHGEPGVQQVAFGDARNAMDMVLDK
LAPRIGEEPHVAILNNLGATTPLEMSVLTHVLTTSAKAKNIKHIIGPAPLMTSLDMHGFSLSVLPVDETILPHLGYRVDM
PAWPGMQTISAPAVIALPDGLSPVQPTASDNDQTRRLVAHACDLLIASEAELNALDAKSGDGDTGSTLATAARDLKGALD
RLPLADPAQLFRALSNELSQTMGGSSGVILAIFFGAAGDAAAKGLPPAKALVSGLERISEVGGATKGDRTMIDALEPALH
ALNEGIAAAATAARKGASETASIGQAKAGRASYVPEENLIGHNDPGAEAVARLFEGLATLA

Sequences:

>Translated_541_residues
MTQFINKKETLVTDAIDGLLASAGGSLRRLDGYPHIKVVCRADWDKSQVALISGGGSGHEPAHAGFVGRGMLTAAVCGEV
FASPSVDAVLAALLAVTGPAGCLLIVKNYTGDRLNFGLAAERARALGLKVSMVVVGDDIALPDLPQPRGVAGTLFVHKIA
GAMAEQGAPLEDICKAAQNAIERMATIGMSLDTCTVPGAQKEDRIATGMAELGLGIHGEPGVQQVAFGDARNAMDMVLDK
LAPRIGEEPHVAILNNLGATTPLEMSVLTHVLTTSAKAKNIKHIIGPAPLMTSLDMHGFSLSVLPVDETILPHLGYRVDM
PAWPGMQTISAPAVIALPDGLSPVQPTASDNDQTRRLVAHACDLLIASEAELNALDAKSGDGDTGSTLATAARDLKGALD
RLPLADPAQLFRALSNELSQTMGGSSGVILAIFFGAAGDAAAKGLPPAKALVSGLERISEVGGATKGDRTMIDALEPALH
ALNEGIAAAATAARKGASETASIGQAKAGRASYVPEENLIGHNDPGAEAVARLFEGLATLA
>Mature_540_residues
TQFINKKETLVTDAIDGLLASAGGSLRRLDGYPHIKVVCRADWDKSQVALISGGGSGHEPAHAGFVGRGMLTAAVCGEVF
ASPSVDAVLAALLAVTGPAGCLLIVKNYTGDRLNFGLAAERARALGLKVSMVVVGDDIALPDLPQPRGVAGTLFVHKIAG
AMAEQGAPLEDICKAAQNAIERMATIGMSLDTCTVPGAQKEDRIATGMAELGLGIHGEPGVQQVAFGDARNAMDMVLDKL
APRIGEEPHVAILNNLGATTPLEMSVLTHVLTTSAKAKNIKHIIGPAPLMTSLDMHGFSLSVLPVDETILPHLGYRVDMP
AWPGMQTISAPAVIALPDGLSPVQPTASDNDQTRRLVAHACDLLIASEAELNALDAKSGDGDTGSTLATAARDLKGALDR
LPLADPAQLFRALSNELSQTMGGSSGVILAIFFGAAGDAAAKGLPPAKALVSGLERISEVGGATKGDRTMIDALEPALHA
LNEGIAAAATAARKGASETASIGQAKAGRASYVPEENLIGHNDPGAEAVARLFEGLATLA

Specific function: Catalyzes the phosphorylation of dihydroxyacetone [H]

COG id: COG2376

COG function: function code G; Dihydroxyacetone kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DhaL domain [H]

Homologues:

Organism=Homo sapiens, GI20149621, Length=563, Percent_Identity=38.898756660746, Blast_Score=313, Evalue=3e-85,
Organism=Escherichia coli, GI87081857, Length=357, Percent_Identity=35.8543417366947, Blast_Score=181, Evalue=1e-46,
Organism=Caenorhabditis elegans, GI17565018, Length=559, Percent_Identity=37.567084078712, Blast_Score=298, Evalue=5e-81,
Organism=Saccharomyces cerevisiae, GI6323570, Length=562, Percent_Identity=35.5871886120996, Blast_Score=273, Evalue=4e-74,
Organism=Saccharomyces cerevisiae, GI6321055, Length=560, Percent_Identity=34.2857142857143, Blast_Score=242, Evalue=1e-64,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004006
- InterPro:   IPR004007
- InterPro:   IPR012734 [H]

Pfam domain/function: PF02733 Dak1; PF02734 Dak2 [H]

EC number: =2.7.1.29 [H]

Molecular weight: Translated: 55484; Mature: 55353

Theoretical pI: Translated: 5.19; Mature: 5.19

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQFINKKETLVTDAIDGLLASAGGSLRRLDGYPHIKVVCRADWDKSQVALISGGGSGHE
CCCCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCCEEEEEECCCCCCCEEEEECCCCCCC
PAHAGFVGRGMLTAAVCGEVFASPSVDAVLAALLAVTGPAGCLLIVKNYTGDRLNFGLAA
CCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHH
ERARALGLKVSMVVVGDDIALPDLPQPRGVAGTLFVHKIAGAMAEQGAPLEDICKAAQNA
HHHHHHCCEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
IERMATIGMSLDTCTVPGAQKEDRIATGMAELGLGIHGEPGVQQVAFGDARNAMDMVLDK
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHCCCHHHHHHHHHHH
LAPRIGEEPHVAILNNLGATTPLEMSVLTHVLTTSAKAKNIKHIIGPAPLMTSLDMHGFS
HHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHCCHHHHCHHHHHCCCHHHHHCCCCCCE
LSVLPVDETILPHLGYRVDMPAWPGMQTISAPAVIALPDGLSPVQPTASDNDQTRRLVAH
EEEEECCHHHHHHCCCEECCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHH
ACDLLIASEAELNALDAKSGDGDTGSTLATAARDLKGALDRLPLADPAQLFRALSNELSQ
HHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
TMGGSSGVILAIFFGAAGDAAAKGLPPAKALVSGLERISEVGGATKGDRTMIDALEPALH
HHCCCCCEEEEEEECCCCCHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
ALNEGIAAAATAARKGASETASIGQAKAGRASYVPEENLIGHNDPGAEAVARLFEGLATL
HHHCCHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHC
A
C
>Mature Secondary Structure 
TQFINKKETLVTDAIDGLLASAGGSLRRLDGYPHIKVVCRADWDKSQVALISGGGSGHE
CCCCCCHHHHHHHHHHHHHHHCCCCEEECCCCCCEEEEEECCCCCCCEEEEECCCCCCC
PAHAGFVGRGMLTAAVCGEVFASPSVDAVLAALLAVTGPAGCLLIVKNYTGDRLNFGLAA
CCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCCHHH
ERARALGLKVSMVVVGDDIALPDLPQPRGVAGTLFVHKIAGAMAEQGAPLEDICKAAQNA
HHHHHHCCEEEEEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCHHHHHHHHHHH
IERMATIGMSLDTCTVPGAQKEDRIATGMAELGLGIHGEPGVQQVAFGDARNAMDMVLDK
HHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCHHHHCCCHHHHHHHHHHH
LAPRIGEEPHVAILNNLGATTPLEMSVLTHVLTTSAKAKNIKHIIGPAPLMTSLDMHGFS
HHHHHCCCCCEEEECCCCCCCCHHHHHHHHHHHCCHHHHCHHHHHCCCHHHHHCCCCCCE
LSVLPVDETILPHLGYRVDMPAWPGMQTISAPAVIALPDGLSPVQPTASDNDQTRRLVAH
EEEEECCHHHHHHCCCEECCCCCCCCCCCCCCEEEECCCCCCCCCCCCCCCHHHHHHHHH
ACDLLIASEAELNALDAKSGDGDTGSTLATAARDLKGALDRLPLADPAQLFRALSNELSQ
HHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
TMGGSSGVILAIFFGAAGDAAAKGLPPAKALVSGLERISEVGGATKGDRTMIDALEPALH
HHCCCCCEEEEEEECCCCCHHHCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHH
ALNEGIAAAATAARKGASETASIGQAKAGRASYVPEENLIGHNDPGAEAVARLFEGLATL
HHHCCHHHHHHHHHCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHC
A
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA