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The map label for this gene is surA [H]

Identifier: 110680309

GI number: 110680309

Start: 2999853

End: 3001073

Strand: Direct

Name: surA [H]

Synonym: RD1_3122

Alternate gene names: 110680309

Gene position: 2999853-3001073 (Clockwise)

Preceding gene: 110680308

Following gene: 110680310

Centisome position: 72.58

GC content: 61.26

Gene sequence:

>1221_bases
ATGATCCGAATTAAACAGTTTTGCAGCGTCCTTGCGCTTTGTGCTGCATGCAGCCTTGCCCCGCCCCTTGGCGCGCAAAA
CCTGTTCAGCCCGGCCATTCAGGTCAATGATGCGGTGATCACAGAATTCGAGATCGAACAACGTCAGCAATTCCTGACCT
TGCTGAACGCGCCCGGCTCAAGCCGTCAGGCCGTGGTTGAGGAATTGATCAACGAGCGCCTGCGCGCGCAGGCGGTTGCA
AACGCAGGTCTCGAACTGTCAGACGCCGCCTTGCAGGAGGGCATGACCGAATTTGCCGGTCGGGTGAACCTTGGCGTTGA
CGAATTCAAGACGGTGCTTGAGGAAAACGGGATCGCCGCCGAAACATTTGAGGATTTCGTGCGCGTGGGCGTATCCTGGC
GTGATTTCATCGCGGCCCGCTTTGGCCCGCGCCTGCAGGTCTCCGAAGAGGAAATTGATCAGGCGCTTGGCAGCACCAAC
GGGGCGAGCAATATTCAGGTGCTCGTCTCCGAGATCATCATCCCCGCGCCGCCCTCACGCGCGGTGGAAGTACAGGAAGT
GGCCGAACAAATCGCCGTGACAACTTCAACGGAAGAGTTCTCTGAGTATGCGCGCCGCTTTTCGGCCACGGCCACTCGCG
ATCAGGGCGGGCGACTGGACTGGCAGCCGCTGAGCAACCTGCCGCCAAGCCTGCGTCCGCTGCTCTTGGGTCTGGCACCG
GGAGAAGTGACGGAACCGCTGAACATTCCCGAAGCCGTGGCGTTGTTCCAGCTGCGTGACATTCGCGAAACCGGTGCGTC
AACGCCTGAATTCGCAGCGATTGACTATGCGGTCTATTATATTCCGGGCGGGCGCAGCCCGGCGGGCCTGCAACAGGCGG
CCCGGGTCGAGGCGCAGGTTGATGTCTGTGACGACCTCTACGGTGTGGCGCAGGGCCAGCCGCCCGAGGTCCTTGAGCGG
GGCAGCAAGCCACCCTCCGAAATACCCACCGACATCGCTGTTGAACTCAGCAAGCTGGATCCCGGCGAAACCTCGATTGC
CCTGACACGGGCCGAGGGGCAAACGCTGCTGTTCCTGATGATGTGTGGGCGCACGGCAGCCGCCAACGAAGATGTGGGCC
GGGATGAGGCCGCACGGGCTTTGCGCAGCAGCAGGCTGAACGCGATTGCAGAGAGCTTTCTGGAACAACTGCGCGCGGAT
GCCAGAATTCGCATCCAATGA

Upstream 100 bases:

>100_bases
ATTGAGCCTTCCACCAGTTTCGGCTTATCCATCGGGCTGTCGGGCTTTTCGGCCAAACGGGGAACGGACACTTATGCCAA
AACATGCGGGTGACAGACAG

Downstream 100 bases:

>100_bases
GCCCTGCAACGGCCCCCGTCCTGATCAGTTGCGGTGAACCTGCCGGGATCGGCCCCGAAATCGCCGTCGCCGCGTGGGAT
GCGCTCCAAGGGACAATCCC

Product: peptidyl-prolyl cis-trans isomerase SurA, putative

Products: NA

Alternate protein names: Peptidyl-prolyl cis-trans isomerase surA; PPIase surA; Rotamase surA [H]

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MIRIKQFCSVLALCAACSLAPPLGAQNLFSPAIQVNDAVITEFEIEQRQQFLTLLNAPGSSRQAVVEELINERLRAQAVA
NAGLELSDAALQEGMTEFAGRVNLGVDEFKTVLEENGIAAETFEDFVRVGVSWRDFIAARFGPRLQVSEEEIDQALGSTN
GASNIQVLVSEIIIPAPPSRAVEVQEVAEQIAVTTSTEEFSEYARRFSATATRDQGGRLDWQPLSNLPPSLRPLLLGLAP
GEVTEPLNIPEAVALFQLRDIRETGASTPEFAAIDYAVYYIPGGRSPAGLQQAARVEAQVDVCDDLYGVAQGQPPEVLER
GSKPPSEIPTDIAVELSKLDPGETSIALTRAEGQTLLFLMMCGRTAAANEDVGRDEAARALRSSRLNAIAESFLEQLRAD
ARIRIQ

Sequences:

>Translated_406_residues
MIRIKQFCSVLALCAACSLAPPLGAQNLFSPAIQVNDAVITEFEIEQRQQFLTLLNAPGSSRQAVVEELINERLRAQAVA
NAGLELSDAALQEGMTEFAGRVNLGVDEFKTVLEENGIAAETFEDFVRVGVSWRDFIAARFGPRLQVSEEEIDQALGSTN
GASNIQVLVSEIIIPAPPSRAVEVQEVAEQIAVTTSTEEFSEYARRFSATATRDQGGRLDWQPLSNLPPSLRPLLLGLAP
GEVTEPLNIPEAVALFQLRDIRETGASTPEFAAIDYAVYYIPGGRSPAGLQQAARVEAQVDVCDDLYGVAQGQPPEVLER
GSKPPSEIPTDIAVELSKLDPGETSIALTRAEGQTLLFLMMCGRTAAANEDVGRDEAARALRSSRLNAIAESFLEQLRAD
ARIRIQ
>Mature_406_residues
MIRIKQFCSVLALCAACSLAPPLGAQNLFSPAIQVNDAVITEFEIEQRQQFLTLLNAPGSSRQAVVEELINERLRAQAVA
NAGLELSDAALQEGMTEFAGRVNLGVDEFKTVLEENGIAAETFEDFVRVGVSWRDFIAARFGPRLQVSEEEIDQALGSTN
GASNIQVLVSEIIIPAPPSRAVEVQEVAEQIAVTTSTEEFSEYARRFSATATRDQGGRLDWQPLSNLPPSLRPLLLGLAP
GEVTEPLNIPEAVALFQLRDIRETGASTPEFAAIDYAVYYIPGGRSPAGLQQAARVEAQVDVCDDLYGVAQGQPPEVLER
GSKPPSEIPTDIAVELSKLDPGETSIALTRAEGQTLLFLMMCGRTAAANEDVGRDEAARALRSSRLNAIAESFLEQLRAD
ARIRIQ

Specific function: Chaperone involved in the correct folding and assembly of outer membrane proteins. It recognizes specific patterns of aromatic residues and the orientation of their side chains, which are found more frequently in integral outer membrane proteins. May act

COG id: COG0760

COG function: function code O; Parvulin-like peptidyl-prolyl isomerase

Gene ontology:

Cell location: Periplasm. Note=Is capable of associating with the outer membrane (By similarity) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PpiC domains [H]

Homologues:

Organism=Escherichia coli, GI1786238, Length=364, Percent_Identity=21.1538461538462, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: 400 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 160 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000297
- InterPro:   IPR023034
- InterPro:   IPR015391
- InterPro:   IPR008880 [H]

Pfam domain/function: PF00639 Rotamase; PF09312 SurA_N [H]

EC number: =5.2.1.8 [H]

Molecular weight: Translated: 43904; Mature: 43904

Theoretical pI: Translated: 4.20; Mature: 4.20

Prosite motif: PS00443 GATASE_TYPE_II ; PS50198 PPIC_PPIASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRIKQFCSVLALCAACSLAPPLGAQNLFSPAIQVNDAVITEFEIEQRQQFLTLLNAPGS
CCCHHHHHHHHHHHHHHHCCCCCCCHHHHCCHHCCCCHHHHHHHHHHHHHHHHHHCCCCC
SRQAVVEELINERLRAQAVANAGLELSDAALQEGMTEFAGRVNLGVDEFKTVLEENGIAA
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCH
ETFEDFVRVGVSWRDFIAARFGPRLQVSEEEIDQALGSTNGASNIQVLVSEIIIPAPPSR
HHHHHHHHHCCCHHHHHHHHCCCCCEECHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCC
AVEVQEVAEQIAVTTSTEEFSEYARRFSATATRDQGGRLDWQPLSNLPPSLRPLLLGLAP
CEEHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHEECCC
GEVTEPLNIPEAVALFQLRDIRETGASTPEFAAIDYAVYYIPGGRSPAGLQQAARVEAQV
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHHH
DVCDDLYGVAQGQPPEVLERGSKPPSEIPTDIAVELSKLDPGETSIALTRAEGQTLLFLM
HHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCEEEECCCCCCCCEEEEEECCCCEEEEEE
MCGRTAAANEDVGRDEAARALRSSRLNAIAESFLEQLRADARIRIQ
ECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECC
>Mature Secondary Structure
MIRIKQFCSVLALCAACSLAPPLGAQNLFSPAIQVNDAVITEFEIEQRQQFLTLLNAPGS
CCCHHHHHHHHHHHHHHHCCCCCCCHHHHCCHHCCCCHHHHHHHHHHHHHHHHHHCCCCC
SRQAVVEELINERLRAQAVANAGLELSDAALQEGMTEFAGRVNLGVDEFKTVLEENGIAA
HHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCH
ETFEDFVRVGVSWRDFIAARFGPRLQVSEEEIDQALGSTNGASNIQVLVSEIIIPAPPSR
HHHHHHHHHCCCHHHHHHHHCCCCCEECHHHHHHHHCCCCCCCHHHHHHHHHHCCCCCCC
AVEVQEVAEQIAVTTSTEEFSEYARRFSATATRDQGGRLDWQPLSNLPPSLRPLLLGLAP
CEEHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCHHHHHEECCC
GEVTEPLNIPEAVALFQLRDIRETGASTPEFAAIDYAVYYIPGGRSPAGLQQAARVEAQV
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCCEEEEEEEEEEECCCCCCHHHHHHHHHHHHH
DVCDDLYGVAQGQPPEVLERGSKPPSEIPTDIAVELSKLDPGETSIALTRAEGQTLLFLM
HHHHHHHHHCCCCCHHHHHCCCCCCCCCCCCCEEEECCCCCCCCEEEEEECCCCEEEEEE
MCGRTAAANEDVGRDEAARALRSSRLNAIAESFLEQLRADARIRIQ
ECCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA