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The map label for this gene is pdxA

Identifier: 110680310

GI number: 110680310

Start: 3001070

End: 3002050

Strand: Direct

Name: pdxA

Synonym: RD1_3123

Alternate gene names: 110680310

Gene position: 3001070-3002050 (Clockwise)

Preceding gene: 110680309

Following gene: 110680311

Centisome position: 72.61

GC content: 64.22

Gene sequence:

>981_bases
ATGAGCCCTGCAACGGCCCCCGTCCTGATCAGTTGCGGTGAACCTGCCGGGATCGGCCCCGAAATCGCCGTCGCCGCGTG
GGATGCGCTCCAAGGGACAATCCCGCTGGCCTGGGTGGGGGATCCGCGCCATTTGCCTGCCAGTACGACGTTTACGGCAA
TCACCCACCCGCGCGCGGTTGCCGATGTGCCGACAGGTTCGCTGCCCGTTCTGGTCCATGACTTTGCCGCGCCCAGCACG
CCGGGCCACCCCGACCCTGCCAACGCACAAGGCGTGATCGACGTGATCGCGGCTTGCGTCGCTTGGGTTCAGGAGGGCGC
CGCCGCAGCCCTGTGCACAGCGCCCATTCACAAAAAGGCACTGATTGATGGCGCTGATTTCAAACATCCCGGGCATACCG
AATACCTGCAAGCCCTGGCGGGTGGCAGGTCACGGGCGGTCATGATGCTGGCCAGCGATGCGCTGCGTGTGGTGCCCACA
ACGATCCATATTGCCCTTGAAGACGTCCCCCGGGTGCTGACACCAGCGTTGCTGAGGGAGACGATCACGATCACCCACGC
TGCCTTGCAGCGGCAATTCGGCATCCAGGCCCCGAGGATCGTCGTTGCCGGCCTGAACCCTCACGCTGGTGAAGGGGGTG
CGATGGGGCTGGAGGAACAGGACTGGATTGCGGATGTGATTTCTGCGCTGGCGGCGAGCGGCATGAACCTGCGCGGCCCC
CTGCCCGCCGATACCATGTTTCACGCCCGCGCCCGCGAGGGATATGACGCCGCGATTGCCATGTATCATGATCAGGCGCT
CATCCCGATCAAGACGCTGGATTTTGATCGCGGGGTCAATGTGACGCTGGGCCTGCCCTTTATCCGCACATCCCCCGATC
ACGGCACGGCCTTTGATATTGCGGGCAAGGGCATCGCCAATCCGACCAGCATGATCGAGGCGATCAAGCTGGCCGCGCAT
ATGGCGGCCCGGCATGTCTGA

Upstream 100 bases:

>100_bases
GCCGGGATGAGGCCGCACGGGCTTTGCGCAGCAGCAGGCTGAACGCGATTGCAGAGAGCTTTCTGGAACAACTGCGCGCG
GATGCCAGAATTCGCATCCA

Downstream 100 bases:

>100_bases
CGGGACGCCCTGCGGGTGCAGGCGCCCATGAGCACGATCGACCACCTGCCCCCCTTGCGCAGCGTCATCCGGGATCATGA
TCTGTCGGCGCGTAAATCCA

Product: 4-hydroxythreonine-4-phosphate dehydrogenase

Products: NA

Alternate protein names: 4-(phosphohydroxy)-L-threonine dehydrogenase

Number of amino acids: Translated: 326; Mature: 325

Protein sequence:

>326_residues
MSPATAPVLISCGEPAGIGPEIAVAAWDALQGTIPLAWVGDPRHLPASTTFTAITHPRAVADVPTGSLPVLVHDFAAPST
PGHPDPANAQGVIDVIAACVAWVQEGAAAALCTAPIHKKALIDGADFKHPGHTEYLQALAGGRSRAVMMLASDALRVVPT
TIHIALEDVPRVLTPALLRETITITHAALQRQFGIQAPRIVVAGLNPHAGEGGAMGLEEQDWIADVISALAASGMNLRGP
LPADTMFHARAREGYDAAIAMYHDQALIPIKTLDFDRGVNVTLGLPFIRTSPDHGTAFDIAGKGIANPTSMIEAIKLAAH
MAARHV

Sequences:

>Translated_326_residues
MSPATAPVLISCGEPAGIGPEIAVAAWDALQGTIPLAWVGDPRHLPASTTFTAITHPRAVADVPTGSLPVLVHDFAAPST
PGHPDPANAQGVIDVIAACVAWVQEGAAAALCTAPIHKKALIDGADFKHPGHTEYLQALAGGRSRAVMMLASDALRVVPT
TIHIALEDVPRVLTPALLRETITITHAALQRQFGIQAPRIVVAGLNPHAGEGGAMGLEEQDWIADVISALAASGMNLRGP
LPADTMFHARAREGYDAAIAMYHDQALIPIKTLDFDRGVNVTLGLPFIRTSPDHGTAFDIAGKGIANPTSMIEAIKLAAH
MAARHV
>Mature_325_residues
SPATAPVLISCGEPAGIGPEIAVAAWDALQGTIPLAWVGDPRHLPASTTFTAITHPRAVADVPTGSLPVLVHDFAAPSTP
GHPDPANAQGVIDVIAACVAWVQEGAAAALCTAPIHKKALIDGADFKHPGHTEYLQALAGGRSRAVMMLASDALRVVPTT
IHIALEDVPRVLTPALLRETITITHAALQRQFGIQAPRIVVAGLNPHAGEGGAMGLEEQDWIADVISALAASGMNLRGPL
PADTMFHARAREGYDAAIAMYHDQALIPIKTLDFDRGVNVTLGLPFIRTSPDHGTAFDIAGKGIANPTSMIEAIKLAAHM
AARHV

Specific function: Catalyzes the NAD(P)-dependent oxidation of 4- (phosphohydroxy)-L-threonine (HTP) into 2-amino-3-oxo-4- (phosphohydroxy)butyric acid which spontaneously decarboxylates to form 3-amino-2-oxopropyl phosphate (AHAP)

COG id: COG1995

COG function: function code H; Pyridoxal phosphate biosynthesis protein

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pdxA family

Homologues:

Organism=Escherichia coli, GI1786237, Length=333, Percent_Identity=42.9429429429429, Blast_Score=231, Evalue=5e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PDXA_ROSDO (Q164G2)

Other databases:

- EMBL:   CP000362
- RefSeq:   YP_683317.1
- ProteinModelPortal:   Q164G2
- SMR:   Q164G2
- STRING:   Q164G2
- GeneID:   4198668
- GenomeReviews:   CP000362_GR
- KEGG:   rde:RD1_3123
- NMPDR:   fig|375451.6.peg.2898
- eggNOG:   COG1995
- HOGENOM:   HBG451136
- OMA:   LETAYQM
- PhylomeDB:   Q164G2
- ProtClustDB:   PRK05312
- BioCyc:   RDEN375451:RD1_3123-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00536
- InterPro:   IPR001804
- InterPro:   IPR005255
- Gene3D:   G3DSA:3.40.718.10
- PANTHER:   PTHR11835
- TIGRFAMs:   TIGR00557

Pfam domain/function: PF04166 PdxA

EC number: =1.1.1.262

Molecular weight: Translated: 33952; Mature: 33821

Theoretical pI: Translated: 6.34; Mature: 6.34

Prosite motif: NA

Important sites: BINDING 132-132 BINDING 133-133 BINDING 271-271 BINDING 280-280 BINDING 289-289

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPATAPVLISCGEPAGIGPEIAVAAWDALQGTIPLAWVGDPRHLPASTTFTAITHPRAV
CCCCCCCEEEECCCCCCCCCCCEEEEHHHHCCCEEEEEECCCCCCCCCCEEEEECCCCCE
ADVPTGSLPVLVHDFAAPSTPGHPDPANAQGVIDVIAACVAWVQEGAAAALCTAPIHKKA
ECCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCHHHH
LIDGADFKHPGHTEYLQALAGGRSRAVMMLASDALRVVPTTIHIALEDVPRVLTPALLRE
EECCCCCCCCCHHHHHHHHHCCCCEEEEEEECCCCEEECEEEEEEHHHHHHHHHHHHHHH
TITITHAALQRQFGIQAPRIVVAGLNPHAGEGGAMGLEEQDWIADVISALAASGMNLRGP
HHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCC
LPADTMFHARAREGYDAAIAMYHDQALIPIKTLDFDRGVNVTLGLPFIRTSPDHGTAFDI
CCCCHHHHHHHCCCCCEEEEEEECCEEEEEEEECCCCCCEEEEECCEEEECCCCCCEEEE
AGKGIANPTSMIEAIKLAAHMAARHV
CCCCCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
SPATAPVLISCGEPAGIGPEIAVAAWDALQGTIPLAWVGDPRHLPASTTFTAITHPRAV
CCCCCCEEEECCCCCCCCCCCEEEEHHHHCCCEEEEEECCCCCCCCCCEEEEECCCCCE
ADVPTGSLPVLVHDFAAPSTPGHPDPANAQGVIDVIAACVAWVQEGAAAALCTAPIHKKA
ECCCCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCEEEECCCCHHHH
LIDGADFKHPGHTEYLQALAGGRSRAVMMLASDALRVVPTTIHIALEDVPRVLTPALLRE
EECCCCCCCCCHHHHHHHHHCCCCEEEEEEECCCCEEECEEEEEEHHHHHHHHHHHHHHH
TITITHAALQRQFGIQAPRIVVAGLNPHAGEGGAMGLEEQDWIADVISALAASGMNLRGP
HHHHHHHHHHHHHCCCCCEEEEECCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCC
LPADTMFHARAREGYDAAIAMYHDQALIPIKTLDFDRGVNVTLGLPFIRTSPDHGTAFDI
CCCCHHHHHHHCCCCCEEEEEEECCEEEEEEEECCCCCCEEEEECCEEEECCCCCCEEEE
AGKGIANPTSMIEAIKLAAHMAARHV
CCCCCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA