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The map label for this gene is aroK [H]

Identifier: 110680277

GI number: 110680277

Start: 2962257

End: 2962850

Strand: Reverse

Name: aroK [H]

Synonym: RD1_3088

Alternate gene names: 110680277

Gene position: 2962850-2962257 (Counterclockwise)

Preceding gene: 110680282

Following gene: 110680276

Centisome position: 71.69

GC content: 58.25

Gene sequence:

>594_bases
ATGAGCGAAATTGAGCAAACCGGAAGTGAAACGGGTCAAACACATCGATTTGTGTTGAAAAAGACAGTTGTGATGATCGG
AATGATGGGGGCGGGCAAGACGGCTGTTGGTCGTGCGCTTGCGCAATTGCTGGATGTGCCTTTTCTTGATTCGGATCATG
AAATCGAAGCAGCGGCCAATATGACCGTGCCTGAAATATTTGCGCGCGATGGCGAGGCTTTCTTTCGGGCGCGCGAGAGC
GAGGTGATCAACCGACTACTGGGTGGGCAGGCTTGTGTGTTGTCAACCGGTGGCGGGGCCTTTCTGGCAGAGGCGAACCG
CGCGGCCATTTCGGCGCGCGGTGTGTCGGTCTGGCTAGATGCGGATATCGACCTGTTGTGGAGCAGGGTCAAACACCGCG
ACACCCGACCGCTGTTGCGCACCGCTGACCCCAAGGCGACGCTTACCGCGCTTTTTGAAACGCGGGTGCCGGAATATGCC
AAGGCGGATATCACCGTGCCTTGTGCGCCACCCGTGGCGATTGAACAGATGGCCCGGCGCGTAGCCGATGTGCTGGTGTC
ACGTCCGGATGTGCTGGAGGTTGCAGATGCTTGA

Upstream 100 bases:

>100_bases
CAGGAATTTGAAGAATCGGAGCATTATACTGCCTTTATGCCTGCCGTTTTCTTTAAGTTATATATGGCCTTTTTCATAAT
ATCACGTCATTCAATCGAAT

Downstream 100 bases:

>100_bases
CACGGTGCGTGTTGATCTGCCCGGGCGCGCTTATGATGTGCGGATCGGGTCGGGGCTGCTCCCGGAGGCGGGCGGGCATG
TCCTGCCGCTGCTCAAGCGG

Product: shikimate kinase

Products: NA

Alternate protein names: SK [H]

Number of amino acids: Translated: 197; Mature: 196

Protein sequence:

>197_residues
MSEIEQTGSETGQTHRFVLKKTVVMIGMMGAGKTAVGRALAQLLDVPFLDSDHEIEAAANMTVPEIFARDGEAFFRARES
EVINRLLGGQACVLSTGGGAFLAEANRAAISARGVSVWLDADIDLLWSRVKHRDTRPLLRTADPKATLTALFETRVPEYA
KADITVPCAPPVAIEQMARRVADVLVSRPDVLEVADA

Sequences:

>Translated_197_residues
MSEIEQTGSETGQTHRFVLKKTVVMIGMMGAGKTAVGRALAQLLDVPFLDSDHEIEAAANMTVPEIFARDGEAFFRARES
EVINRLLGGQACVLSTGGGAFLAEANRAAISARGVSVWLDADIDLLWSRVKHRDTRPLLRTADPKATLTALFETRVPEYA
KADITVPCAPPVAIEQMARRVADVLVSRPDVLEVADA
>Mature_196_residues
SEIEQTGSETGQTHRFVLKKTVVMIGMMGAGKTAVGRALAQLLDVPFLDSDHEIEAAANMTVPEIFARDGEAFFRARESE
VINRLLGGQACVLSTGGGAFLAEANRAAISARGVSVWLDADIDLLWSRVKHRDTRPLLRTADPKATLTALFETRVPEYAK
ADITVPCAPPVAIEQMARRVADVLVSRPDVLEVADA

Specific function: Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate [H]

COG id: COG0703

COG function: function code E; Shikimate kinase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate kinase family [H]

Homologues:

Organism=Escherichia coli, GI87082255, Length=169, Percent_Identity=39.6449704142012, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1786587, Length=124, Percent_Identity=37.9032258064516, Blast_Score=80, Evalue=1e-16,

Paralogues:

None

Copy number: 140 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 200 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000623
- InterPro:   IPR023000 [H]

Pfam domain/function: PF01202 SKI [H]

EC number: =2.7.1.71 [H]

Molecular weight: Translated: 21258; Mature: 21126

Theoretical pI: Translated: 5.09; Mature: 5.09

Prosite motif: PS01128 SHIKIMATE_KINASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEIEQTGSETGQTHRFVLKKTVVMIGMMGAGKTAVGRALAQLLDVPFLDSDHEIEAAAN
CCCHHHCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHCC
MTVPEIFARDGEAFFRARESEVINRLLGGQACVLSTGGGAFLAEANRAAISARGVSVWLD
CCHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEECCCCCEEEECCEEEEEE
ADIDLLWSRVKHRDTRPLLRTADPKATLTALFETRVPEYAKADITVPCAPPVAIEQMARR
CCHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHCCCCHHCCCEEECCCCCHHHHHHHHH
VADVLVSRPDVLEVADA
HHHHHHCCCCCEECCCC
>Mature Secondary Structure 
SEIEQTGSETGQTHRFVLKKTVVMIGMMGAGKTAVGRALAQLLDVPFLDSDHEIEAAAN
CCHHHCCCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHCC
MTVPEIFARDGEAFFRARESEVINRLLGGQACVLSTGGGAFLAEANRAAISARGVSVWLD
CCHHHHHHCCCHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEECCCCCEEEECCEEEEEE
ADIDLLWSRVKHRDTRPLLRTADPKATLTALFETRVPEYAKADITVPCAPPVAIEQMARR
CCHHHHHHHHHHCCCCCHHHCCCCHHHHHHHHHHCCCCHHCCCEEECCCCCHHHHHHHHH
VADVLVSRPDVLEVADA
HHHHHHCCCCCEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA