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The map label for this gene is aroB

Identifier: 110680276

GI number: 110680276

Start: 2961152

End: 2962264

Strand: Reverse

Name: aroB

Synonym: RD1_3087

Alternate gene names: 110680276

Gene position: 2962264-2961152 (Counterclockwise)

Preceding gene: 110680277

Following gene: 110680271

Centisome position: 71.67

GC content: 63.43

Gene sequence:

>1113_bases
ATGCTTGACACGGTGCGTGTTGATCTGCCCGGGCGCGCTTATGATGTGCGGATCGGGTCGGGGCTGCTCCCGGAGGCGGG
CGGGCATGTCCTGCCGCTGCTCAAGCGGCCACGGGTTGCCGTGGTAACGGATGAAACCGTCGCGGGGCTGCATCTTGAGG
CTTTGCGCGCGGGGCTTGCGCGTGACGGCATCGAGATGAGCGCGCTGGCGCTGCCTGCGGGGGAGGCCACGAAGTCCTGG
GCGCCGCTGGAGCGTACCGTCGGCTGGCTGCTGGATCAGAAGGTCGAGCGCGGCGATGTCGTGGTGGCTTTCGGCGGCGG
TGTCATTGGTGATCTTGTCGGATTTGCGGCCGCCATTCTGCGCCGGGGCGTGCGGTTTGTGCAAATCCCCACGTCACTGT
TGGCGCAGGTGGACAGTTCTGTCGGCGGCAAGACCGGGATCAACGCGGCGCAGGGCAAGAACCTGATCGGCGCGTTTCAT
CAACCCAGTCTGGTGCTGGCGGATATCGACGTGCTCGGGTCACTGACGGCGCGCGATTTTCTGGCGGGTTACGGCGAAGT
GGTCAAATACGGCCTGCTGGGTGATCTGACGTTCTTCGAGTGGCTGGAGCAGAACGGACCTGCTCTGGCAGCAGGTGACA
AGGGCGCGCGTTGCGAAGCCGTACGCCGCTCGGTGCAGATGAAGGCCGATATCGTGATCCGCGATGAGACAGAGCAGGGC
GATCGCGCGCTGCTCAATCTGGGTCATACCTTTGGGCATGCGCTTGAGGCCGCAACGGGCTATTCGGACCGGCTGTTGCA
CGGCGAGGGGGTCGCGATTGGCTGTGCCCTGGCGTTTGAGTTATCCGCGCGCATGGGCTTGTGTTCGCAGGAAAGTCCAA
GCCGGGTGCGCGCGCATCTCAAGGCGATGGGGATGAAGACCGATTTGCATGACATCCCCGGCGATCTGCCCGATGCCGCC
TGTTTGCTGGACCTGATGGGGCAGGACAAGAAAGTCACGCAAGGAAAGCTGCATTTCATCCTTGCGCGTGGGTTGGGTGA
AGCCTTCGTCACCTCTGACGTTGCGGCCTCGGACGTGCTGATGGTTCTGGAGGATGCGCTGCGCTCAAAATAA

Upstream 100 bases:

>100_bases
GATATCACCGTGCCTTGTGCGCCACCCGTGGCGATTGAACAGATGGCCCGGCGCGTAGCCGATGTGCTGGTGTCACGTCC
GGATGTGCTGGAGGTTGCAG

Downstream 100 bases:

>100_bases
ACCGCGACGTGCATCCGAATTGGATGCCGTGGGAAGTGGTGCGCTGCGATCCATCGGTGCAAGACAGATCGCAGCGCTAT
TCCAGTCATTCGCGCAACAG

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 370; Mature: 370

Protein sequence:

>370_residues
MLDTVRVDLPGRAYDVRIGSGLLPEAGGHVLPLLKRPRVAVVTDETVAGLHLEALRAGLARDGIEMSALALPAGEATKSW
APLERTVGWLLDQKVERGDVVVAFGGGVIGDLVGFAAAILRRGVRFVQIPTSLLAQVDSSVGGKTGINAAQGKNLIGAFH
QPSLVLADIDVLGSLTARDFLAGYGEVVKYGLLGDLTFFEWLEQNGPALAAGDKGARCEAVRRSVQMKADIVIRDETEQG
DRALLNLGHTFGHALEAATGYSDRLLHGEGVAIGCALAFELSARMGLCSQESPSRVRAHLKAMGMKTDLHDIPGDLPDAA
CLLDLMGQDKKVTQGKLHFILARGLGEAFVTSDVAASDVLMVLEDALRSK

Sequences:

>Translated_370_residues
MLDTVRVDLPGRAYDVRIGSGLLPEAGGHVLPLLKRPRVAVVTDETVAGLHLEALRAGLARDGIEMSALALPAGEATKSW
APLERTVGWLLDQKVERGDVVVAFGGGVIGDLVGFAAAILRRGVRFVQIPTSLLAQVDSSVGGKTGINAAQGKNLIGAFH
QPSLVLADIDVLGSLTARDFLAGYGEVVKYGLLGDLTFFEWLEQNGPALAAGDKGARCEAVRRSVQMKADIVIRDETEQG
DRALLNLGHTFGHALEAATGYSDRLLHGEGVAIGCALAFELSARMGLCSQESPSRVRAHLKAMGMKTDLHDIPGDLPDAA
CLLDLMGQDKKVTQGKLHFILARGLGEAFVTSDVAASDVLMVLEDALRSK
>Mature_370_residues
MLDTVRVDLPGRAYDVRIGSGLLPEAGGHVLPLLKRPRVAVVTDETVAGLHLEALRAGLARDGIEMSALALPAGEATKSW
APLERTVGWLLDQKVERGDVVVAFGGGVIGDLVGFAAAILRRGVRFVQIPTSLLAQVDSSVGGKTGINAAQGKNLIGAFH
QPSLVLADIDVLGSLTARDFLAGYGEVVKYGLLGDLTFFEWLEQNGPALAAGDKGARCEAVRRSVQMKADIVIRDETEQG
DRALLNLGHTFGHALEAATGYSDRLLHGEGVAIGCALAFELSARMGLCSQESPSRVRAHLKAMGMKTDLHDIPGDLPDAA
CLLDLMGQDKKVTQGKLHFILARGLGEAFVTSDVAASDVLMVLEDALRSK

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family

Homologues:

Organism=Escherichia coli, GI1789791, Length=365, Percent_Identity=44.1095890410959, Blast_Score=266, Evalue=2e-72,
Organism=Saccharomyces cerevisiae, GI6320332, Length=344, Percent_Identity=35.7558139534884, Blast_Score=171, Evalue=2e-43,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROB_ROSDO (Q164J6)

Other databases:

- EMBL:   CP000362
- RefSeq:   YP_683283.1
- ProteinModelPortal:   Q164J6
- SMR:   Q164J6
- STRING:   Q164J6
- GeneID:   4198712
- GenomeReviews:   CP000362_GR
- KEGG:   rde:RD1_3087
- NMPDR:   fig|375451.6.peg.2865
- eggNOG:   COG0337
- HOGENOM:   HBG632303
- OMA:   GWIDESI
- PhylomeDB:   Q164J6
- ProtClustDB:   PRK00002
- BioCyc:   RDEN375451:RD1_3087-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00110
- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037
- PANTHER:   PTHR21090:SF1
- PIRSF:   PIRSF001455
- TIGRFAMs:   TIGR01357

Pfam domain/function: PF01761 DHQ_synthase

EC number: =4.2.3.4

Molecular weight: Translated: 39084; Mature: 39084

Theoretical pI: Translated: 5.85; Mature: 5.85

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLDTVRVDLPGRAYDVRIGSGLLPEAGGHVLPLLKRPRVAVVTDETVAGLHLEALRAGLA
CCCEEEEECCCCEEEEEECCCCCCCCCCCEEHHCCCCCEEEEECCCHHHHHHHHHHHHHH
RDGIEMSALALPAGEATKSWAPLERTVGWLLDQKVERGDVVVAFGGGVIGDLVGFAAAIL
HCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHH
RRGVRFVQIPTSLLAQVDSSVGGKTGINAAQGKNLIGAFHQPSLVLADIDVLGSLTARDF
HCCCEEEEECHHHHHHHHHCCCCCCCCCHHCCCCCEECCCCCCEEEEEHHHHHHHHHHHH
LAGYGEVVKYGLLGDLTFFEWLEQNGPALAAGDKGARCEAVRRSVQMKADIVIRDETEQG
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHCEEEEEEECCCCCC
DRALLNLGHTFGHALEAATGYSDRLLHGEGVAIGCALAFELSARMGLCSQESPSRVRAHL
CHHHHHHHHHHHHHHHHHCCCCCCEECCCCCEEEHHHHHHHHHHHCCCCCCCHHHHHHHH
KAMGMKTDLHDIPGDLPDAACLLDLMGQDKKVTQGKLHFILARGLGEAFVTSDVAASDVL
HHHCCCCCHHHCCCCCCHHHHHHHHHCCCCCCCCCCEEEEEEHHCCHHHHHHHHHHHHHH
MVLEDALRSK
HHHHHHHHCC
>Mature Secondary Structure
MLDTVRVDLPGRAYDVRIGSGLLPEAGGHVLPLLKRPRVAVVTDETVAGLHLEALRAGLA
CCCEEEEECCCCEEEEEECCCCCCCCCCCEEHHCCCCCEEEEECCCHHHHHHHHHHHHHH
RDGIEMSALALPAGEATKSWAPLERTVGWLLDQKVERGDVVVAFGGGVIGDLVGFAAAIL
HCCCCEEEEECCCCCCCCCCCCHHHHHHHHHHHCCCCCCEEEEECCCHHHHHHHHHHHHH
RRGVRFVQIPTSLLAQVDSSVGGKTGINAAQGKNLIGAFHQPSLVLADIDVLGSLTARDF
HCCCEEEEECHHHHHHHHHCCCCCCCCCHHCCCCCEECCCCCCEEEEEHHHHHHHHHHHH
LAGYGEVVKYGLLGDLTFFEWLEQNGPALAAGDKGARCEAVRRSVQMKADIVIRDETEQG
HHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCCHHHHHHHHHHCEEEEEEECCCCCC
DRALLNLGHTFGHALEAATGYSDRLLHGEGVAIGCALAFELSARMGLCSQESPSRVRAHL
CHHHHHHHHHHHHHHHHHCCCCCCEECCCCCEEEHHHHHHHHHHHCCCCCCCHHHHHHHH
KAMGMKTDLHDIPGDLPDAACLLDLMGQDKKVTQGKLHFILARGLGEAFVTSDVAASDVL
HHHCCCCCHHHCCCCCCHHHHHHHHHCCCCCCCCCCEEEEEEHHCCHHHHHHHHHHHHHH
MVLEDALRSK
HHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA