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The map label for this gene is gcvT [H]

Identifier: 110680282

GI number: 110680282

Start: 2967089

End: 2969512

Strand: Reverse

Name: gcvT [H]

Synonym: RD1_3093

Alternate gene names: 110680282

Gene position: 2969512-2967089 (Counterclockwise)

Preceding gene: 110680283

Following gene: 110680277

Centisome position: 71.85

GC content: 61.72

Gene sequence:

>2424_bases
ATGCGTACTCATGCCCAAGCCGTTGTCATCGGAGGCGGTGTCATCGGCTGCTCGATCCTCTATCATCTGACCAAATTGGG
CTGGACAGATGTGGTGCTGCTGGAGCGTGACGAACTGACCAGCGGGTCGACCTGGCATGCGGCGGCAAACATCCACGGGC
TGCATGACAACAACAATATCACGCGCATTCAGAACTATACGATGGACCTCTATAACGCGCTGGAAGCCGAAACCGGGCAG
TCCTGCGGCGTGTTCCAGCCCGGCTCGCTTTATCTCGCGCAGACCGAGGCGCGCGAACACCAGTTGCGCCTGCAGGCGGC
GAAGGCGAAATACTACGGGCTGCACTTTCACGAGGTCAGCCGGGACGAGGCCGAACGCCTGCATCCGCTGGTCGATTTTG
ACGGTATCCGCTGCATCATGTTCGAACCCTCCGGCGGGAATGTGGACCCATCCGGTGTCACCAACGCCTATGCCACCGGC
GCACGCCAGAATGGTGCCGAAATCATCCGCTTTTGCCCGGTGACGGCCACGGAGCAGCGGCCGGATGGCACATGGATCGT
GCGCACGACCAAAGGTGATATTGCCACCGAATGGGTCGTGAATGCGGCTGGCCTCTGGGGGCGCGAGGTGGCGGCATTGG
CCGGGTTAGCACTGCCTTTGCAGCCGACCGAGCATCAGTATTTTGTCACCGAAACCATCGCCGAGATCGCAGCACTGGAT
CGCCGTTTGCCATCGGTGGCCGACCGGGACGGCGAATACTATCTGCGTCAGGAGGGCAAAGGGTTGCTTGTCGGTGCCTA
TGAAAAGGACCTGCGCTTCTGGGCCGAGGACGGCACGCCGCAGGGCTTTGGGCACGAGTTGTTCGCCGATGATCTGGAGC
GGATCGAAGACAATATGATGCGCGCCATCGACCGCGTCCCCGCCGTCGGAGAGGCGGGGATCAAACGCGTGATCAACGGG
CCGATGATCTGGTCGCCCGATGCCAATGTCCTGTTCGGCCCTGCGCCGGAACTGTCGAACTACTTCTGCTGCAACGGGAT
CATTCCGGGGTTTTCGCAGTCGGGTGGCATGGGGCTGTTGGCGGCGGATTGGATCGTCACGGGTGAGACGCGCTATGACA
TGTTCGCATGGGACATGGCGCGGTTCGGGACATGGGCGGATAAGGCCTTCACCAAGGCGCGTGTTGGCGATCAATACGCA
AACCGGTTCAAAATCCACTTCCCGAATGAAGAACGCAGTGCGGGTCGCCCCCTGCGCCGTCGTCCCGTCTACGACATGCA
ACGGCAACGTGGGGCGGTCTTCGGGCTGAACTACGGATGGGAACACCCGCTGTATTTCGGCTATCCCGAAGGGGCCGAAG
ACCACACCGAAGGGTTCACGCGGCAGGATTGGTGGCATCAGGTCGGTGCGGAATGCCGGATGCTGCGCGAGAACGCAGGG
GTCATTGATATCTCGAATTTCGCGACATACCGCTGCGCCGGGCCGGGGGCCGAAGGCTGGCTGAATAGTGTTTTCGCCAA
TACCATGCCCAGGGTGGTGGGGCGGTCCTGTCTCACGCCGCTGATTGGCAAGCGGGGCGGTATCGCGGGGGATTTCACCG
TCACGCGTCTGGGGGAAGAGGAATTCTGGGTAATCGGCTCGGGCATGGCCGAACGCTATCACCAGCGGTTTTTCAAGGCT
GTGCCCTTGCCCCGCGACACCACATTTGAAAGCCACACCGATGCGATGTGCGGTTTCAACGTCGCCGGACCGAAGTCGCG
CGACATGCTGCAACCGCTCACCAAGACGTCACTGTCTACCGAGGACTTTCCGTTCATGCGTTCGCGATGGATTGAACTGG
GCGGTGTCAGGGTCCTGGCCTTGCGCGTCAGCTTTACCGGCGATCTGGGGTGGGAATTACACTGTGCGCGCGAGGATCAG
GCGCAGCTTTACGCGGCCTTGCTTGCAGCGGGCAAAGAGGTGGGCGCGGGTCCGGTGGGCAGCCGCGCCTTGATGAGCCT
GCGTGTTGAAAAAGGGTACGGGTCATGGGGGCGCGAATACAGCCCCGAATACTGGCCGCAGGAGGTCGGCCTTGATCGGT
TGTGCAGGATGGACAAGGCATTCCTGAACAAGGACGCCGTTGCGCAAACACTTGGCAACCCCGCGCGCGAACATCTTGTC
ATGCTGGCATTGGACAGCGGGCAAATCGATGCATCAAACGCGGACGCCACAGGGGGCGAGCCGATTTTCAAAGACGGGCG
GGGCATCGGGCGCGTCACCTCCGGTGCGTATGGATACAGCGTCGGGATGAGCCTCGCGCTTGGCTTTGTGAGCGGTGCGC
AACCGGGCGACGTGGTTGAGGTCATGGTGCTGGGTCAGCCGCATCAAGCGCGCATTCTGGCTGACCCCCCGTTTGATCCA
AAAGGGTTGCGGCTGCGCGCGTGA

Upstream 100 bases:

>100_bases
CCTTGTATGCGCGCGACGCGCAATGTCGCAAACCGGCCAACAGCGCGCGCCCCGGCAGGTCAGGGTGGGCCTGTTACACG
CCATCACCGGGGTTTTCAAC

Downstream 100 bases:

>100_bases
TGCGTGGCGCGCGCGTCGCGTCTTGGAAACAGCCGCCCGCGCGCCGTTCAAAGCGCGCGGATCTTGAGCTCCGTAATACG
GTTGCCCTCGCGCGCGCAGA

Product: dimethylglycine dehydrogenase, putative

Products: NA

Alternate protein names: Glycine cleavage system T protein [H]

Number of amino acids: Translated: 807; Mature: 807

Protein sequence:

>807_residues
MRTHAQAVVIGGGVIGCSILYHLTKLGWTDVVLLERDELTSGSTWHAAANIHGLHDNNNITRIQNYTMDLYNALEAETGQ
SCGVFQPGSLYLAQTEAREHQLRLQAAKAKYYGLHFHEVSRDEAERLHPLVDFDGIRCIMFEPSGGNVDPSGVTNAYATG
ARQNGAEIIRFCPVTATEQRPDGTWIVRTTKGDIATEWVVNAAGLWGREVAALAGLALPLQPTEHQYFVTETIAEIAALD
RRLPSVADRDGEYYLRQEGKGLLVGAYEKDLRFWAEDGTPQGFGHELFADDLERIEDNMMRAIDRVPAVGEAGIKRVING
PMIWSPDANVLFGPAPELSNYFCCNGIIPGFSQSGGMGLLAADWIVTGETRYDMFAWDMARFGTWADKAFTKARVGDQYA
NRFKIHFPNEERSAGRPLRRRPVYDMQRQRGAVFGLNYGWEHPLYFGYPEGAEDHTEGFTRQDWWHQVGAECRMLRENAG
VIDISNFATYRCAGPGAEGWLNSVFANTMPRVVGRSCLTPLIGKRGGIAGDFTVTRLGEEEFWVIGSGMAERYHQRFFKA
VPLPRDTTFESHTDAMCGFNVAGPKSRDMLQPLTKTSLSTEDFPFMRSRWIELGGVRVLALRVSFTGDLGWELHCAREDQ
AQLYAALLAAGKEVGAGPVGSRALMSLRVEKGYGSWGREYSPEYWPQEVGLDRLCRMDKAFLNKDAVAQTLGNPAREHLV
MLALDSGQIDASNADATGGEPIFKDGRGIGRVTSGAYGYSVGMSLALGFVSGAQPGDVVEVMVLGQPHQARILADPPFDP
KGLRLRA

Sequences:

>Translated_807_residues
MRTHAQAVVIGGGVIGCSILYHLTKLGWTDVVLLERDELTSGSTWHAAANIHGLHDNNNITRIQNYTMDLYNALEAETGQ
SCGVFQPGSLYLAQTEAREHQLRLQAAKAKYYGLHFHEVSRDEAERLHPLVDFDGIRCIMFEPSGGNVDPSGVTNAYATG
ARQNGAEIIRFCPVTATEQRPDGTWIVRTTKGDIATEWVVNAAGLWGREVAALAGLALPLQPTEHQYFVTETIAEIAALD
RRLPSVADRDGEYYLRQEGKGLLVGAYEKDLRFWAEDGTPQGFGHELFADDLERIEDNMMRAIDRVPAVGEAGIKRVING
PMIWSPDANVLFGPAPELSNYFCCNGIIPGFSQSGGMGLLAADWIVTGETRYDMFAWDMARFGTWADKAFTKARVGDQYA
NRFKIHFPNEERSAGRPLRRRPVYDMQRQRGAVFGLNYGWEHPLYFGYPEGAEDHTEGFTRQDWWHQVGAECRMLRENAG
VIDISNFATYRCAGPGAEGWLNSVFANTMPRVVGRSCLTPLIGKRGGIAGDFTVTRLGEEEFWVIGSGMAERYHQRFFKA
VPLPRDTTFESHTDAMCGFNVAGPKSRDMLQPLTKTSLSTEDFPFMRSRWIELGGVRVLALRVSFTGDLGWELHCAREDQ
AQLYAALLAAGKEVGAGPVGSRALMSLRVEKGYGSWGREYSPEYWPQEVGLDRLCRMDKAFLNKDAVAQTLGNPAREHLV
MLALDSGQIDASNADATGGEPIFKDGRGIGRVTSGAYGYSVGMSLALGFVSGAQPGDVVEVMVLGQPHQARILADPPFDP
KGLRLRA
>Mature_807_residues
MRTHAQAVVIGGGVIGCSILYHLTKLGWTDVVLLERDELTSGSTWHAAANIHGLHDNNNITRIQNYTMDLYNALEAETGQ
SCGVFQPGSLYLAQTEAREHQLRLQAAKAKYYGLHFHEVSRDEAERLHPLVDFDGIRCIMFEPSGGNVDPSGVTNAYATG
ARQNGAEIIRFCPVTATEQRPDGTWIVRTTKGDIATEWVVNAAGLWGREVAALAGLALPLQPTEHQYFVTETIAEIAALD
RRLPSVADRDGEYYLRQEGKGLLVGAYEKDLRFWAEDGTPQGFGHELFADDLERIEDNMMRAIDRVPAVGEAGIKRVING
PMIWSPDANVLFGPAPELSNYFCCNGIIPGFSQSGGMGLLAADWIVTGETRYDMFAWDMARFGTWADKAFTKARVGDQYA
NRFKIHFPNEERSAGRPLRRRPVYDMQRQRGAVFGLNYGWEHPLYFGYPEGAEDHTEGFTRQDWWHQVGAECRMLRENAG
VIDISNFATYRCAGPGAEGWLNSVFANTMPRVVGRSCLTPLIGKRGGIAGDFTVTRLGEEEFWVIGSGMAERYHQRFFKA
VPLPRDTTFESHTDAMCGFNVAGPKSRDMLQPLTKTSLSTEDFPFMRSRWIELGGVRVLALRVSFTGDLGWELHCAREDQ
AQLYAALLAAGKEVGAGPVGSRALMSLRVEKGYGSWGREYSPEYWPQEVGLDRLCRMDKAFLNKDAVAQTLGNPAREHLV
MLALDSGQIDASNADATGGEPIFKDGRGIGRVTSGAYGYSVGMSLALGFVSGAQPGDVVEVMVLGQPHQARILADPPFDP
KGLRLRA

Specific function: The glycine cleavage system catalyzes the degradation of glycine [H]

COG id: COG0665

COG function: function code E; Glycine/D-amino acid oxidases (deaminating)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gcvT family [H]

Homologues:

Organism=Homo sapiens, GI24797151, Length=806, Percent_Identity=36.1042183622829, Blast_Score=540, Evalue=1e-153,
Organism=Homo sapiens, GI197927446, Length=864, Percent_Identity=31.1342592592593, Blast_Score=392, Evalue=1e-109,
Organism=Homo sapiens, GI21361378, Length=864, Percent_Identity=31.1342592592593, Blast_Score=392, Evalue=1e-109,
Organism=Homo sapiens, GI194306651, Length=784, Percent_Identity=28.8265306122449, Blast_Score=330, Evalue=3e-90,
Organism=Caenorhabditis elegans, GI71994045, Length=802, Percent_Identity=29.3017456359102, Blast_Score=299, Evalue=3e-81,
Organism=Caenorhabditis elegans, GI71994052, Length=809, Percent_Identity=28.9245982694685, Blast_Score=296, Evalue=2e-80,
Organism=Caenorhabditis elegans, GI32563613, Length=805, Percent_Identity=27.7018633540373, Blast_Score=258, Evalue=7e-69,
Organism=Saccharomyces cerevisiae, GI6320222, Length=287, Percent_Identity=25.0871080139373, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI20130091, Length=861, Percent_Identity=29.732868757259, Blast_Score=344, Evalue=1e-94,
Organism=Drosophila melanogaster, GI28571104, Length=791, Percent_Identity=29.582806573957, Blast_Score=318, Evalue=1e-86,
Organism=Drosophila melanogaster, GI20129441, Length=392, Percent_Identity=26.2755102040816, Blast_Score=84, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013977
- InterPro:   IPR006222
- InterPro:   IPR006223
- InterPro:   IPR022903 [H]

Pfam domain/function: PF01571 GCV_T; PF08669 GCV_T_C [H]

EC number: =2.1.2.10 [H]

Molecular weight: Translated: 89040; Mature: 89040

Theoretical pI: Translated: 5.83; Mature: 5.83

Prosite motif: PS00013 PROKAR_LIPOPROTEIN ; PS00092 N6_MTASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTHAQAVVIGGGVIGCSILYHLTKLGWTDVVLLERDELTSGSTWHAAANIHGLHDNNNI
CCCCCCEEEEECHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEEEEEEEEECCCCCE
TRIQNYTMDLYNALEAETGQSCGVFQPGSLYLAQTEAREHQLRLQAAKAKYYGLHFHEVS
EEEEHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHEEEEEHHHCC
RDEAERLHPLVDFDGIRCIMFEPSGGNVDPSGVTNAYATGARQNGAEIIRFCPVTATEQR
HHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHCCCCCCCCEEEEECCCCCCCCC
PDGTWIVRTTKGDIATEWVVNAAGLWGREVAALAGLALPLQPTEHQYFVTETIAEIAALD
CCCCEEEEECCCCCHHHHHHHCCCCCHHHHHHHHCEECCCCCCCCCCHHHHHHHHHHHHH
RRLPSVADRDGEYYLRQEGKGLLVGAYEKDLRFWAEDGTPQGFGHELFADDLERIEDNMM
HHCCCCCCCCCCEEEEECCCEEEEEEEHHCCCEEECCCCCCCCCCHHHHHHHHHHHHHHH
RAIDRVPAVGEAGIKRVINGPMIWSPDANVLFGPAPELSNYFCCNGIIPGFSQSGGMGLL
HHHHHCCCCCHHHHHHHHCCCEEECCCCCEEECCCCCCCCEEEECCCCCCCCCCCCCEEE
AADWIVTGETRYDMFAWDMARFGTWADKAFTKARVGDQYANRFKIHFPNEERSAGRPLRR
EECEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHCCHHHHCEEEEECCCCHHHCCCCHHC
RPVYDMQRQRGAVFGLNYGWEHPLYFGYPEGAEDHTEGFTRQDWWHQVGAECRMLRENAG
CCCHHHHHHCCCEEEECCCCCCCEEECCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHCCC
VIDISNFATYRCAGPGAEGWLNSVFANTMPRVVGRSCLTPLIGKRGGIAGDFTVTRLGEE
EEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCC
EFWVIGSGMAERYHQRFFKAVPLPRDTTFESHTDAMCGFNVAGPKSRDMLQPLTKTSLST
CEEEEECHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCC
EDFPFMRSRWIELGGVRVLALRVSFTGDLGWELHCAREDQAQLYAALLAAGKEVGAGPVG
CCCCHHHHHHHHCCCEEEEEEEEEECCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCC
SRALMSLRVEKGYGSWGREYSPEYWPQEVGLDRLCRMDKAFLNKDAVAQTLGNPAREHLV
CCEEEEEEEECCCCCCCCCCCCCCCCHHCCHHHHHHHHHHHHCHHHHHHHHCCCCCCEEE
MLALDSGQIDASNADATGGEPIFKDGRGIGRVTSGAYGYSVGMSLALGFVSGAQPGDVVE
EEEECCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEE
VMVLGQPHQARILADPPFDPKGLRLRA
EEEECCCCCCEEEECCCCCCCCCEECC
>Mature Secondary Structure
MRTHAQAVVIGGGVIGCSILYHLTKLGWTDVVLLERDELTSGSTWHAAANIHGLHDNNNI
CCCCCCEEEEECHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEEEEEEEEECCCCCE
TRIQNYTMDLYNALEAETGQSCGVFQPGSLYLAQTEAREHQLRLQAAKAKYYGLHFHEVS
EEEEHHHHHHHHHHHHCCCCCCCCCCCCCEEEEECHHHHHHHHHHHHHHHEEEEEHHHCC
RDEAERLHPLVDFDGIRCIMFEPSGGNVDPSGVTNAYATGARQNGAEIIRFCPVTATEQR
HHHHHHHCCCCCCCCEEEEEEECCCCCCCCCCCCHHHHCCCCCCCCEEEEECCCCCCCCC
PDGTWIVRTTKGDIATEWVVNAAGLWGREVAALAGLALPLQPTEHQYFVTETIAEIAALD
CCCCEEEEECCCCCHHHHHHHCCCCCHHHHHHHHCEECCCCCCCCCCHHHHHHHHHHHHH
RRLPSVADRDGEYYLRQEGKGLLVGAYEKDLRFWAEDGTPQGFGHELFADDLERIEDNMM
HHCCCCCCCCCCEEEEECCCEEEEEEEHHCCCEEECCCCCCCCCCHHHHHHHHHHHHHHH
RAIDRVPAVGEAGIKRVINGPMIWSPDANVLFGPAPELSNYFCCNGIIPGFSQSGGMGLL
HHHHHCCCCCHHHHHHHHCCCEEECCCCCEEECCCCCCCCEEEECCCCCCCCCCCCCEEE
AADWIVTGETRYDMFAWDMARFGTWADKAFTKARVGDQYANRFKIHFPNEERSAGRPLRR
EECEEEECCCCCHHHHHHHHHHCCHHHHHHHHHHCCHHHHCEEEEECCCCHHHCCCCHHC
RPVYDMQRQRGAVFGLNYGWEHPLYFGYPEGAEDHTEGFTRQDWWHQVGAECRMLRENAG
CCCHHHHHHCCCEEEECCCCCCCEEECCCCCCCHHHCCCCHHHHHHHHHHHHHHHHHCCC
VIDISNFATYRCAGPGAEGWLNSVFANTMPRVVGRSCLTPLIGKRGGIAGDFTVTRLGEE
EEEECCCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCC
EFWVIGSGMAERYHQRFFKAVPLPRDTTFESHTDAMCGFNVAGPKSRDMLQPLTKTSLST
CEEEEECHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCC
EDFPFMRSRWIELGGVRVLALRVSFTGDLGWELHCAREDQAQLYAALLAAGKEVGAGPVG
CCCCHHHHHHHHCCCEEEEEEEEEECCCCCEEEEECCCHHHHHHHHHHHCCCCCCCCCCC
SRALMSLRVEKGYGSWGREYSPEYWPQEVGLDRLCRMDKAFLNKDAVAQTLGNPAREHLV
CCEEEEEEEECCCCCCCCCCCCCCCCHHCCHHHHHHHHHHHHCHHHHHHHHCCCCCCEEE
MLALDSGQIDASNADATGGEPIFKDGRGIGRVTSGAYGYSVGMSLALGFVSGAQPGDVVE
EEEECCCCCCCCCCCCCCCCCHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCEEE
VMVLGQPHQARILADPPFDPKGLRLRA
EEEECCCCCCEEEECCCCCCCCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA