BacMap

Definition	Roseobacter denitrificans OCh 114, complete genome.
Accession	NC_008209
Length	4,133,097

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The map label for this gene is bdhA [H]

Identifier: 110679951

GI number: 110679951

Start: 2609130

End: 2609915

Strand: Reverse

Name: bdhA [H]

Synonym: RD1_2738

Alternate gene names: 110679951

Gene position: 2609915-2609130 (Counterclockwise)

Preceding gene: 110679952

Following gene: 110679950

Centisome position: 63.15

GC content: 59.16

Gene sequence:

>786_bases
ATGAGTTTCGAGATTTCTCTTTCCGGTAAAACGGCCATCGTGACAGGGTCAAATTCGGGCATCGGGCTGGGTATTGCATG
GGAATTGGCGCGCGCTGGTGCGGATATCGTGATCAACTCTTTCAGTGACACCGCCGAAGACCATGCGCTCGCGAAAGAGA
TCGCGCAGGAAACGGGCGTCACGGCGCGCTATATCCAGGCGGACATGTCCAAGCCCGATGATTGCCGCGCGCTGATCACC
AAGGCGGGCAACTGTGATATTCTGGTCAACAACGCCGGCATCCAGCATGTCGCGGGCATCCCCGATTTTCCGGTTGAGAA
ATGGGATGCGATCATTGCGATCAACCTGTCCTCGGCGTTTCACACCACCGCCGTGGCCTTGCCGATGATGCGCGCCGCAG
GCTGGGGCAGGGTGATCAATATCGCCTCGGCGCATGGGTTGACCGCGTCGCCCTATAAATCGGCCTATATCGCGGCCAAA
CACGGCATCGTCGGGCTGACCAAGACGACGGCGCTGGAAACCGCGAAAGAACCGATCACCGCCAATGCGATCTGTCCGGG
GTATGTGCTGACACCGATTGTCGAAAAGCAGATTCCCGACACCATGAAGGAATACGACATGACGCGCGAAGAGGTCATCG
AGAACGTGATGCTGACGCGGCAGCCGTCGAAAGAGTTTGCAACGGTCGAGCAAATGGGCGGCACCGCGACGTTTTTGTGC
TCGGACGCCGCCGCACAGATCACGGGGACGACGATCAGCGTCGATGGCGGCTGGACGGCGCTGTAA

Upstream 100 bases:

>100_bases
TGGGGCGCGTGAGCCGTTTTCCGCTTTTGGCATTTTATTTGCACGCGCAGCACGTCATGATGCGTGCAATGCAGCATTAT
GAACAAGCAAGGACATCGCC

Downstream 100 bases:

>100_bases
CGGCCTGTTGTCTCCTGTTGCTATAGGAACGGGCGCAGGTATCTTTGACAAATCGACCAGAAGGGGCGATGGAAAATGGC
GAAAAAACGGATCAACCTCG

Product: D-beta-hydroxybutyrate dehydrogenase

Products: NA

Alternate protein names: BDH; 3-hydroxybutyrate dehydrogenase; 3-HBDH [H]

Number of amino acids: Translated: 261; Mature: 260

Protein sequence:

>261_residues
MSFEISLSGKTAIVTGSNSGIGLGIAWELARAGADIVINSFSDTAEDHALAKEIAQETGVTARYIQADMSKPDDCRALIT
KAGNCDILVNNAGIQHVAGIPDFPVEKWDAIIAINLSSAFHTTAVALPMMRAAGWGRVINIASAHGLTASPYKSAYIAAK
HGIVGLTKTTALETAKEPITANAICPGYVLTPIVEKQIPDTMKEYDMTREEVIENVMLTRQPSKEFATVEQMGGTATFLC
SDAAAQITGTTISVDGGWTAL

Sequences:

>Translated_261_residues
MSFEISLSGKTAIVTGSNSGIGLGIAWELARAGADIVINSFSDTAEDHALAKEIAQETGVTARYIQADMSKPDDCRALIT
KAGNCDILVNNAGIQHVAGIPDFPVEKWDAIIAINLSSAFHTTAVALPMMRAAGWGRVINIASAHGLTASPYKSAYIAAK
HGIVGLTKTTALETAKEPITANAICPGYVLTPIVEKQIPDTMKEYDMTREEVIENVMLTRQPSKEFATVEQMGGTATFLC
SDAAAQITGTTISVDGGWTAL
>Mature_260_residues
SFEISLSGKTAIVTGSNSGIGLGIAWELARAGADIVINSFSDTAEDHALAKEIAQETGVTARYIQADMSKPDDCRALITK
AGNCDILVNNAGIQHVAGIPDFPVEKWDAIIAINLSSAFHTTAVALPMMRAAGWGRVINIASAHGLTASPYKSAYIAAKH
GIVGLTKTTALETAKEPITANAICPGYVLTPIVEKQIPDTMKEYDMTREEVIENVMLTRQPSKEFATVEQMGGTATFLCS
DAAAQITGTTISVDGGWTAL

Specific function: Unknown

COG id: COG1028

COG function: function code IQR; Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI32483357, Length=262, Percent_Identity=32.824427480916, Blast_Score=116, Evalue=2e-26,
Organism=Homo sapiens, GI66933014, Length=254, Percent_Identity=28.740157480315, Blast_Score=106, Evalue=2e-23,
Organism=Homo sapiens, GI5031737, Length=260, Percent_Identity=32.6923076923077, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI15277342, Length=268, Percent_Identity=29.1044776119403, Blast_Score=97, Evalue=1e-20,
Organism=Homo sapiens, GI31542939, Length=239, Percent_Identity=30.1255230125523, Blast_Score=92, Evalue=5e-19,
Organism=Homo sapiens, GI33667109, Length=190, Percent_Identity=35.2631578947368, Blast_Score=90, Evalue=2e-18,
Organism=Homo sapiens, GI7705925, Length=259, Percent_Identity=28.1853281853282, Blast_Score=86, Evalue=3e-17,
Organism=Homo sapiens, GI4504505, Length=194, Percent_Identity=28.3505154639175, Blast_Score=84, Evalue=1e-16,
Organism=Homo sapiens, GI4503301, Length=261, Percent_Identity=31.0344827586207, Blast_Score=83, Evalue=2e-16,
Organism=Homo sapiens, GI19923817, Length=266, Percent_Identity=28.1954887218045, Blast_Score=82, Evalue=4e-16,
Organism=Homo sapiens, GI126723750, Length=269, Percent_Identity=28.6245353159851, Blast_Score=81, Evalue=1e-15,
Organism=Homo sapiens, GI126723191, Length=189, Percent_Identity=31.7460317460317, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI142976729, Length=228, Percent_Identity=28.5087719298246, Blast_Score=79, Evalue=4e-15,
Organism=Homo sapiens, GI40254992, Length=253, Percent_Identity=26.8774703557312, Blast_Score=77, Evalue=1e-14,
Organism=Homo sapiens, GI4557649, Length=213, Percent_Identity=28.6384976525822, Blast_Score=76, Evalue=3e-14,
Organism=Homo sapiens, GI59889578, Length=237, Percent_Identity=29.535864978903, Blast_Score=75, Evalue=5e-14,
Organism=Homo sapiens, GI7706318, Length=213, Percent_Identity=25.8215962441315, Blast_Score=75, Evalue=8e-14,
Organism=Homo sapiens, GI224922801, Length=174, Percent_Identity=31.0344827586207, Blast_Score=73, Evalue=3e-13,
Organism=Homo sapiens, GI7705855, Length=210, Percent_Identity=28.5714285714286, Blast_Score=70, Evalue=1e-12,
Organism=Homo sapiens, GI209862901, Length=237, Percent_Identity=27.8481012658228, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI19923983, Length=237, Percent_Identity=27.8481012658228, Blast_Score=70, Evalue=2e-12,
Organism=Homo sapiens, GI225579078, Length=209, Percent_Identity=31.5789473684211, Blast_Score=68, Evalue=7e-12,
Organism=Homo sapiens, GI40807363, Length=207, Percent_Identity=25.6038647342995, Blast_Score=67, Evalue=1e-11,
Organism=Homo sapiens, GI7657478, Length=228, Percent_Identity=25, Blast_Score=66, Evalue=3e-11,
Organism=Escherichia coli, GI87082160, Length=264, Percent_Identity=34.469696969697, Blast_Score=138, Evalue=3e-34,
Organism=Escherichia coli, GI87082100, Length=258, Percent_Identity=36.8217054263566, Blast_Score=137, Evalue=7e-34,
Organism=Escherichia coli, GI1789208, Length=264, Percent_Identity=35.2272727272727, Blast_Score=133, Evalue=1e-32,
Organism=Escherichia coli, GI1788459, Length=254, Percent_Identity=35.0393700787402, Blast_Score=127, Evalue=5e-31,
Organism=Escherichia coli, GI1787335, Length=264, Percent_Identity=32.5757575757576, Blast_Score=122, Evalue=3e-29,
Organism=Escherichia coli, GI1790717, Length=257, Percent_Identity=30.7392996108949, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1787905, Length=263, Percent_Identity=31.9391634980989, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1789057, Length=256, Percent_Identity=30.078125, Blast_Score=89, Evalue=3e-19,
Organism=Escherichia coli, GI1789378, Length=214, Percent_Identity=29.4392523364486, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI1786812, Length=258, Percent_Identity=27.906976744186, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI2367365, Length=256, Percent_Identity=27.34375, Blast_Score=75, Evalue=5e-15,
Organism=Escherichia coli, GI2367175, Length=256, Percent_Identity=26.5625, Blast_Score=68, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI25147288, Length=261, Percent_Identity=29.5019157088123, Blast_Score=108, Evalue=3e-24,
Organism=Caenorhabditis elegans, GI17555706, Length=257, Percent_Identity=29.5719844357977, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17560676, Length=259, Percent_Identity=30.5019305019305, Blast_Score=105, Evalue=3e-23,
Organism=Caenorhabditis elegans, GI17561402, Length=270, Percent_Identity=31.1111111111111, Blast_Score=100, Evalue=8e-22,
Organism=Caenorhabditis elegans, GI17568967, Length=211, Percent_Identity=30.8056872037915, Blast_Score=91, Evalue=6e-19,
Organism=Caenorhabditis elegans, GI17564282, Length=194, Percent_Identity=32.4742268041237, Blast_Score=87, Evalue=7e-18,
Organism=Caenorhabditis elegans, GI193203117, Length=197, Percent_Identity=30.4568527918782, Blast_Score=87, Evalue=1e-17,
Organism=Caenorhabditis elegans, GI193203115, Length=195, Percent_Identity=30.2564102564103, Blast_Score=84, Evalue=6e-17,
Organism=Caenorhabditis elegans, GI17555612, Length=216, Percent_Identity=31.9444444444444, Blast_Score=84, Evalue=9e-17,
Organism=Caenorhabditis elegans, GI71994604, Length=252, Percent_Identity=28.1746031746032, Blast_Score=83, Evalue=1e-16,
Organism=Caenorhabditis elegans, GI115534694, Length=267, Percent_Identity=28.8389513108614, Blast_Score=80, Evalue=9e-16,
Organism=Caenorhabditis elegans, GI71994600, Length=252, Percent_Identity=27.3809523809524, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17559104, Length=196, Percent_Identity=33.1632653061224, Blast_Score=80, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17562906, Length=281, Percent_Identity=29.1814946619217, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17508895, Length=196, Percent_Identity=28.0612244897959, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17562904, Length=273, Percent_Identity=28.2051282051282, Blast_Score=71, Evalue=5e-13,
Organism=Caenorhabditis elegans, GI17538182, Length=227, Percent_Identity=31.7180616740088, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI193204405, Length=275, Percent_Identity=28, Blast_Score=70, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17562908, Length=275, Percent_Identity=28.3636363636364, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17538480, Length=267, Percent_Identity=26.9662921348315, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17560150, Length=277, Percent_Identity=27.4368231046931, Blast_Score=69, Evalue=3e-12,
Organism=Caenorhabditis elegans, GI17562910, Length=276, Percent_Identity=26.8115942028986, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17531453, Length=277, Percent_Identity=30.3249097472924, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17560332, Length=276, Percent_Identity=29.3478260869565, Blast_Score=68, Evalue=6e-12,
Organism=Caenorhabditis elegans, GI17536025, Length=258, Percent_Identity=27.906976744186, Blast_Score=67, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17562990, Length=270, Percent_Identity=28.5185185185185, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17536651, Length=258, Percent_Identity=25.968992248062, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17551412, Length=204, Percent_Identity=29.9019607843137, Blast_Score=64, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17538486, Length=204, Percent_Identity=30.3921568627451, Blast_Score=64, Evalue=8e-11,
Organism=Saccharomyces cerevisiae, GI6322861, Length=215, Percent_Identity=29.7674418604651, Blast_Score=88, Evalue=2e-18,
Organism=Drosophila melanogaster, GI21355319, Length=259, Percent_Identity=32.046332046332, Blast_Score=121, Evalue=4e-28,
Organism=Drosophila melanogaster, GI23397609, Length=257, Percent_Identity=32.6848249027237, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI28571526, Length=265, Percent_Identity=31.3207547169811, Blast_Score=107, Evalue=1e-23,
Organism=Drosophila melanogaster, GI21357041, Length=265, Percent_Identity=28.3018867924528, Blast_Score=102, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24644339, Length=261, Percent_Identity=27.2030651340996, Blast_Score=101, Evalue=6e-22,
Organism=Drosophila melanogaster, GI24640442, Length=200, Percent_Identity=33.5, Blast_Score=91, Evalue=6e-19,
Organism=Drosophila melanogaster, GI18859837, Length=207, Percent_Identity=28.5024154589372, Blast_Score=88, Evalue=6e-18,
Organism=Drosophila melanogaster, GI24639444, Length=264, Percent_Identity=29.9242424242424, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24643142, Length=253, Percent_Identity=25.296442687747, Blast_Score=81, Evalue=9e-16,
Organism=Drosophila melanogaster, GI161076933, Length=188, Percent_Identity=32.9787234042553, Blast_Score=79, Evalue=4e-15,
Organism=Drosophila melanogaster, GI24584748, Length=188, Percent_Identity=32.9787234042553, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI24649181, Length=194, Percent_Identity=30.4123711340206, Blast_Score=78, Evalue=7e-15,
Organism=Drosophila melanogaster, GI21355631, Length=176, Percent_Identity=31.25, Blast_Score=77, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24584744, Length=193, Percent_Identity=32.1243523316062, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI28574402, Length=193, Percent_Identity=32.1243523316062, Blast_Score=76, Evalue=2e-14,
Organism=Drosophila melanogaster, GI21357673, Length=264, Percent_Identity=27.6515151515151, Blast_Score=75, Evalue=5e-14,
Organism=Drosophila melanogaster, GI21358495, Length=198, Percent_Identity=25.7575757575758, Blast_Score=74, Evalue=7e-14,
Organism=Drosophila melanogaster, GI24665243, Length=206, Percent_Identity=28.6407766990291, Blast_Score=68, Evalue=6e-12,
Organism=Drosophila melanogaster, GI221331218, Length=223, Percent_Identity=29.1479820627803, Blast_Score=67, Evalue=1e-11,
Organism=Drosophila melanogaster, GI24665247, Length=207, Percent_Identity=28.5024154589372, Blast_Score=64, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011294
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.30 [H]

Molecular weight: Translated: 27516; Mature: 27384

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFEISLSGKTAIVTGSNSGIGLGIAWELARAGADIVINSFSDTAEDHALAKEIAQETGV
CEEEEEECCCEEEEECCCCCEEEHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHCC
TARYIQADMSKPDDCRALITKAGNCDILVNNAGIQHVAGIPDFPVEKWDAIIAINLSSAF
EEEEEECCCCCCHHHHHHHHCCCCCEEEEECCCCCEECCCCCCCCCCCCEEEEEEECCHH
HTTAVALPMMRAAGWGRVINIASAHGLTASPYKSAYIAAKHGIVGLTKTTALETAKEPIT
HHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCEEEEECCCEEEEEHHHHHHHHCCCCC
ANAICPGYVLTPIVEKQIPDTMKEYDMTREEVIENVMLTRQPSKEFATVEQMGGTATFLC
CCCCCCCHHHHHHHHHHCHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHCCCEEEEEE
SDAAAQITGTTISVDGGWTAL
CCCCCEEECCEEEECCCEECC
>Mature Secondary Structure 
SFEISLSGKTAIVTGSNSGIGLGIAWELARAGADIVINSFSDTAEDHALAKEIAQETGV
EEEEEECCCEEEEECCCCCEEEHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHCC
TARYIQADMSKPDDCRALITKAGNCDILVNNAGIQHVAGIPDFPVEKWDAIIAINLSSAF
EEEEEECCCCCCHHHHHHHHCCCCCEEEEECCCCCEECCCCCCCCCCCCEEEEEEECCHH
HTTAVALPMMRAAGWGRVINIASAHGLTASPYKSAYIAAKHGIVGLTKTTALETAKEPIT
HHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCCEEEEECCCEEEEEHHHHHHHHCCCCC
ANAICPGYVLTPIVEKQIPDTMKEYDMTREEVIENVMLTRQPSKEFATVEQMGGTATFLC
CCCCCCCHHHHHHHHHHCHHHHHHHCCCHHHHHHHHHHCCCCCHHHHHHHHCCCEEEEEE
SDAAAQITGTTISVDGGWTAL
CCCCCEEECCEEEECCCEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9922248; 11481431 [H]