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The map label for this gene is arsC [H]

Identifier: 110679646

GI number: 110679646

Start: 2284355

End: 2285203

Strand: Direct

Name: arsC [H]

Synonym: RD1_2397

Alternate gene names: 110679646

Gene position: 2284355-2285203 (Clockwise)

Preceding gene: 110679644

Following gene: 110679647

Centisome position: 55.27

GC content: 58.19

Gene sequence:

>849_bases
ATGGAAATAATGATCCCCAACCGACTTTCGACACTCGGCCACCCGCAACGGCTGGCGCTGTTTCGCTTGCTGATGCGGCG
CTATCCTGATCGCGTTCCGGCGACGGAACTGGCCAAGGCGCTTGGGCTGAAGCCGAATACACTGTCGAGCTATGTGAACG
CCCTGATGCAGGCGGGGCTGATCCGTCAAGAGCGGGTTGGCAGGTCCTTGCGGTATGCCATCGACATGGATGCCGCGCGC
GAGACCGTGGATTACCTACTGCACGATTGTTGCCGGGGCAGGCCTGAAATCTGCGTGCCGCATGCATATTTGGCTGCTGA
TAAAGACAAACCGATGTCAGACCGCGGATATACCGTATTGTTTATATGTACCGGCAATTCCGCGCGGTCCATCTTTGCGG
AAACGCTCTTGCGCGACCTCGCCGGTGACAGGTTCACGGCCTGTTCGGCAGGCACCAAGCCGCGCTCGCAACTGAACCCC
TTTGCGCTCACGGTGCTGGAACAAAACGGGCATGATGTATCGCCGCTGCGTGCCAAACATATCTCCGAGTTTCAGGGACC
GGACGCCCCGGATTTCGATTTCGTCTTTACTGTCTGCAATCAGGCAGCCAATGAAGAATGCCCCTCCTGGCCCGGCCAGC
CCATCAGCGCGCATTGGGGCCTGCCCGATCCGGCGACGGTTGAGGGTTCAGATGCAGAAAAAAGCCTCGCTTTTCACCAA
ACCTATGCCGCGCTGCGCAATCGCATGATTGCCTTTGCTGCCTTGCCTGTTGCGTCGCTGGATCGTCTGGCGTTGCAGCA
CGCTGTCGACGGGATCGGCCAATCTACTGACAAAGGATCAAAGATATGA

Upstream 100 bases:

>100_bases
GTTGTGGATCGCCTGATCCGTTTCACGCCCATGATCGTCAGGACCGCCTGTCACAAAAGGTTCACTTTCCATACCTCTAT
AATTCATATATTCGTGAAAT

Downstream 100 bases:

>100_bases
CTGTCTACGCACTCAACGGCCTTGGCCGGATTGGCAAGCTGGCCTTGAAACCGCTGCTGGAACGCGGGGCTGAAATCGCA
TGGATCAACGATGCGGCGGG

Product: arsenate reductase, putative

Products: NA

Alternate protein names: Arsenate reductase; Arsenical pump modifier; Low molecular weight protein-tyrosine-phosphatase [H]

Number of amino acids: Translated: 282; Mature: 282

Protein sequence:

>282_residues
MEIMIPNRLSTLGHPQRLALFRLLMRRYPDRVPATELAKALGLKPNTLSSYVNALMQAGLIRQERVGRSLRYAIDMDAAR
ETVDYLLHDCCRGRPEICVPHAYLAADKDKPMSDRGYTVLFICTGNSARSIFAETLLRDLAGDRFTACSAGTKPRSQLNP
FALTVLEQNGHDVSPLRAKHISEFQGPDAPDFDFVFTVCNQAANEECPSWPGQPISAHWGLPDPATVEGSDAEKSLAFHQ
TYAALRNRMIAFAALPVASLDRLALQHAVDGIGQSTDKGSKI

Sequences:

>Translated_282_residues
MEIMIPNRLSTLGHPQRLALFRLLMRRYPDRVPATELAKALGLKPNTLSSYVNALMQAGLIRQERVGRSLRYAIDMDAAR
ETVDYLLHDCCRGRPEICVPHAYLAADKDKPMSDRGYTVLFICTGNSARSIFAETLLRDLAGDRFTACSAGTKPRSQLNP
FALTVLEQNGHDVSPLRAKHISEFQGPDAPDFDFVFTVCNQAANEECPSWPGQPISAHWGLPDPATVEGSDAEKSLAFHQ
TYAALRNRMIAFAALPVASLDRLALQHAVDGIGQSTDKGSKI
>Mature_282_residues
MEIMIPNRLSTLGHPQRLALFRLLMRRYPDRVPATELAKALGLKPNTLSSYVNALMQAGLIRQERVGRSLRYAIDMDAAR
ETVDYLLHDCCRGRPEICVPHAYLAADKDKPMSDRGYTVLFICTGNSARSIFAETLLRDLAGDRFTACSAGTKPRSQLNP
FALTVLEQNGHDVSPLRAKHISEFQGPDAPDFDFVFTVCNQAANEECPSWPGQPISAHWGLPDPATVEGSDAEKSLAFHQ
TYAALRNRMIAFAALPVASLDRLALQHAVDGIGQSTDKGSKI

Specific function: Reduces arsenate [As(V)] to arsenite [As(III)] and dephosphorylates tyrosine phosphorylated proteins, low-MW aryl phosphates and natural and synthetic acyl phosphates. Could switch between different functions in different circumstances [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase superfamily. ArsC family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014064
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 31021; Mature: 31021

Theoretical pI: Translated: 7.50; Mature: 7.50

Prosite motif: PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
5.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIMIPNRLSTLGHPQRLALFRLLMRRYPDRVPATELAKALGLKPNTLSSYVNALMQAGL
CCEECCCHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHH
IRQERVGRSLRYAIDMDAARETVDYLLHDCCRGRPEICVPHAYLAADKDKPMSDRGYTVL
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCHHHHCCCCCCCCCCCCEEE
FICTGNSARSIFAETLLRDLAGDRFTACSAGTKPRSQLNPFALTVLEQNGHDVSPLRAKH
EEECCCCHHHHHHHHHHHHHCCCCEEECCCCCCCHHHCCCEEEEEEECCCCCCCHHHHHH
ISEFQGPDAPDFDFVFTVCNQAANEECPSWPGQPISAHWGLPDPATVEGSDAEKSLAFHQ
HHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
TYAALRNRMIAFAALPVASLDRLALQHAVDGIGQSTDKGSKI
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MEIMIPNRLSTLGHPQRLALFRLLMRRYPDRVPATELAKALGLKPNTLSSYVNALMQAGL
CCEECCCHHHHCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHHH
IRQERVGRSLRYAIDMDAARETVDYLLHDCCRGRPEICVPHAYLAADKDKPMSDRGYTVL
HHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCCHHHHCCCCCCCCCCCCEEE
FICTGNSARSIFAETLLRDLAGDRFTACSAGTKPRSQLNPFALTVLEQNGHDVSPLRAKH
EEECCCCHHHHHHHHHHHHHCCCCEEECCCCCCCHHHCCCEEEEEEECCCCCCCHHHHHH
ISEFQGPDAPDFDFVFTVCNQAANEECPSWPGQPISAHWGLPDPATVEGSDAEKSLAFHQ
HHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHH
TYAALRNRMIAFAALPVASLDRLALQHAVDGIGQSTDKGSKI
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA