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The map label for this gene is gap [H]

Identifier: 110679647

GI number: 110679647

Start: 2285200

End: 2286198

Strand: Direct

Name: gap [H]

Synonym: RD1_2398

Alternate gene names: 110679647

Gene position: 2285200-2286198 (Clockwise)

Preceding gene: 110679646

Following gene: 110679648

Centisome position: 55.29

GC content: 58.06

Gene sequence:

>999_bases
ATGACTGTCTACGCACTCAACGGCCTTGGCCGGATTGGCAAGCTGGCCTTGAAACCGCTGCTGGAACGCGGGGCTGAAAT
CGCATGGATCAACGATGCGGCGGGTGATCCGGAGATGCACGCCCATCTTCTGGAATTCGACAGCGTCCATGGCCGCTGGA
AGGCCGATTTCGCCCACGCTTCTGACAGCGTGACAATCAATGGCCAGCGTCTGCCGTTCATCGGCACAGGCGACATCGCC
GCGCTGCCACTGGAGGGCGTTGATGTGGTGATTGATTGCACAGGCGTTTTCAAGACAGAGGCGAAAATAGCCCCCTATTT
CGATGCAGGGGTGAAGAAAGTGGTGGTATCGGCCCCGGTCAAGGACGGGGATGCCGCCAATATCGTCTACGGGGTCAATC
ACGATATCTATGCACCGGAGCGTCACCGCATCGTGACCGCGGCCAGTTGCACGACAAATTGTCTGGCGCCGGTCGTAAAG
GTCATTCACGATAATCTGCGGATCAAACATGGTTCCATCACGACGATCCACAATGTGACCAACACGCAGATCATTGTGGA
CCGCCCGGCCAAGGATCTGCGCCGCGCGCGCTCGGCGCTGAATTCCCTCATTCCGACCACGACAGGCAGTGCCACCGCGA
TCACGCTGATCTATCCCGAACTGACGGGCCGCCTGAACGGTCACGCCGTCCGCGTGCCACTGCTCAACGCGTCACTGACT
GATTGCGTGTTCGAAGTGGAACAAGAGACCACTGCTGACGAGGTCAACGCTCTGTTCAAGGCCGCGTCAGAAGGGCCGCT
GAATGGCATCCTCGGCTATGAGGAACGCCCGCTCGTGTCCACGGATTACACAAACGACGAAAGATCCAGCATCATTGATG
CGCTTTCTACCATGGTAATCAATGGCACGCAGGTGAAAGTCTATGCGTGGTATGACAACGAGATGGGGTATGCGCATCGG
CTGGTGGATGTGGCCTGCATGGTCGGGGACAGTCTGTGA

Upstream 100 bases:

>100_bases
TGATTGCCTTTGCTGCCTTGCCTGTTGCGTCGCTGGATCGTCTGGCGTTGCAGCACGCTGTCGACGGGATCGGCCAATCT
ACTGACAAAGGATCAAAGAT

Downstream 100 bases:

>100_bases
CCAAAAGCGCCACGCGCCCAAAGGGCCTGTCGGCCTATATCGCGGTCACGGCGGCCTATTGGGCATTCATGCTGACCGAC
GGTGCCTTGCGCATGCTGGT

Product: glyceraldehyde-3-phosphate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 332; Mature: 331

Protein sequence:

>332_residues
MTVYALNGLGRIGKLALKPLLERGAEIAWINDAAGDPEMHAHLLEFDSVHGRWKADFAHASDSVTINGQRLPFIGTGDIA
ALPLEGVDVVIDCTGVFKTEAKIAPYFDAGVKKVVVSAPVKDGDAANIVYGVNHDIYAPERHRIVTAASCTTNCLAPVVK
VIHDNLRIKHGSITTIHNVTNTQIIVDRPAKDLRRARSALNSLIPTTTGSATAITLIYPELTGRLNGHAVRVPLLNASLT
DCVFEVEQETTADEVNALFKAASEGPLNGILGYEERPLVSTDYTNDERSSIIDALSTMVINGTQVKVYAWYDNEMGYAHR
LVDVACMVGDSL

Sequences:

>Translated_332_residues
MTVYALNGLGRIGKLALKPLLERGAEIAWINDAAGDPEMHAHLLEFDSVHGRWKADFAHASDSVTINGQRLPFIGTGDIA
ALPLEGVDVVIDCTGVFKTEAKIAPYFDAGVKKVVVSAPVKDGDAANIVYGVNHDIYAPERHRIVTAASCTTNCLAPVVK
VIHDNLRIKHGSITTIHNVTNTQIIVDRPAKDLRRARSALNSLIPTTTGSATAITLIYPELTGRLNGHAVRVPLLNASLT
DCVFEVEQETTADEVNALFKAASEGPLNGILGYEERPLVSTDYTNDERSSIIDALSTMVINGTQVKVYAWYDNEMGYAHR
LVDVACMVGDSL
>Mature_331_residues
TVYALNGLGRIGKLALKPLLERGAEIAWINDAAGDPEMHAHLLEFDSVHGRWKADFAHASDSVTINGQRLPFIGTGDIAA
LPLEGVDVVIDCTGVFKTEAKIAPYFDAGVKKVVVSAPVKDGDAANIVYGVNHDIYAPERHRIVTAASCTTNCLAPVVKV
IHDNLRIKHGSITTIHNVTNTQIIVDRPAKDLRRARSALNSLIPTTTGSATAITLIYPELTGRLNGHAVRVPLLNASLTD
CVFEVEQETTADEVNALFKAASEGPLNGILGYEERPLVSTDYTNDERSSIIDALSTMVINGTQVKVYAWYDNEMGYAHRL
VDVACMVGDSL

Specific function: Second phase of glycolysis; first step. [C]

COG id: COG0057

COG function: function code G; Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glyceraldehyde-3-phosphate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI7669492, Length=324, Percent_Identity=40.4320987654321, Blast_Score=244, Evalue=7e-65,
Organism=Homo sapiens, GI7657116, Length=322, Percent_Identity=39.4409937888199, Blast_Score=244, Evalue=1e-64,
Organism=Escherichia coli, GI1788079, Length=324, Percent_Identity=40.7407407407407, Blast_Score=238, Evalue=3e-64,
Organism=Escherichia coli, GI1789295, Length=330, Percent_Identity=40.3030303030303, Blast_Score=233, Evalue=2e-62,
Organism=Caenorhabditis elegans, GI32566163, Length=333, Percent_Identity=39.6396396396396, Blast_Score=243, Evalue=8e-65,
Organism=Caenorhabditis elegans, GI17568413, Length=333, Percent_Identity=39.6396396396396, Blast_Score=243, Evalue=1e-64,
Organism=Caenorhabditis elegans, GI17534677, Length=329, Percent_Identity=39.5136778115502, Blast_Score=242, Evalue=2e-64,
Organism=Caenorhabditis elegans, GI17534679, Length=329, Percent_Identity=38.9057750759878, Blast_Score=240, Evalue=8e-64,
Organism=Saccharomyces cerevisiae, GI6322409, Length=328, Percent_Identity=42.3780487804878, Blast_Score=262, Evalue=6e-71,
Organism=Saccharomyces cerevisiae, GI6322468, Length=328, Percent_Identity=41.4634146341463, Blast_Score=257, Evalue=2e-69,
Organism=Saccharomyces cerevisiae, GI6321631, Length=328, Percent_Identity=41.7682926829268, Blast_Score=255, Evalue=7e-69,
Organism=Drosophila melanogaster, GI85725000, Length=327, Percent_Identity=41.5902140672783, Blast_Score=258, Evalue=3e-69,
Organism=Drosophila melanogaster, GI22023983, Length=327, Percent_Identity=41.5902140672783, Blast_Score=258, Evalue=3e-69,
Organism=Drosophila melanogaster, GI17933600, Length=327, Percent_Identity=40.6727828746177, Blast_Score=255, Evalue=3e-68,
Organism=Drosophila melanogaster, GI18110149, Length=327, Percent_Identity=40.6727828746177, Blast_Score=255, Evalue=3e-68,
Organism=Drosophila melanogaster, GI19922412, Length=328, Percent_Identity=39.0243902439024, Blast_Score=249, Evalue=3e-66,

Paralogues:

None

Copy number: 220 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 740 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1660 Molecules/Cell In: Growth Phase, Min

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020831
- InterPro:   IPR020830
- InterPro:   IPR020829
- InterPro:   IPR020828
- InterPro:   IPR006424
- InterPro:   IPR016040 [H]

Pfam domain/function: PF02800 Gp_dh_C; PF00044 Gp_dh_N [H]

EC number: =1.2.1.12 [H]

Molecular weight: Translated: 35828; Mature: 35697

Theoretical pI: Translated: 5.55; Mature: 5.55

Prosite motif: PS00071 GAPDH

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVYALNGLGRIGKLALKPLLERGAEIAWINDAAGDPEMHAHLLEFDSVHGRWKADFAHA
CEEEEECCCCHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHCCCCCEEECCCCC
SDSVTINGQRLPFIGTGDIAALPLEGVDVVIDCTGVFKTEAKIAPYFDAGVKKVVVSAPV
CCCEEECCCEECEEECCCEEEECCCCCEEEEEECCEEECCCEECCHHHCCCEEEEEECCC
KDGDAANIVYGVNHDIYAPERHRIVTAASCTTNCLAPVVKVIHDNLRIKHGSITTIHNVT
CCCCCCEEEEECCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCEEECCCEEEEEECC
NTQIIVDRPAKDLRRARSALNSLIPTTTGSATAITLIYPELTGRLNGHAVRVPLLNASLT
CCEEEEECCHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCCEEEEEEECCCHH
DCVFEVEQETTADEVNALFKAASEGPLNGILGYEERPLVSTDYTNDERSSIIDALSTMVI
HHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHEE
NGTQVKVYAWYDNEMGYAHRLVDVACMVGDSL
CCCEEEEEEEECCCCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TVYALNGLGRIGKLALKPLLERGAEIAWINDAAGDPEMHAHLLEFDSVHGRWKADFAHA
EEEEECCCCHHHHHHHHHHHHCCCEEEEEECCCCCHHHHHHHHHHHCCCCCEEECCCCC
SDSVTINGQRLPFIGTGDIAALPLEGVDVVIDCTGVFKTEAKIAPYFDAGVKKVVVSAPV
CCCEEECCCEECEEECCCEEEECCCCCEEEEEECCEEECCCEECCHHHCCCEEEEEECCC
KDGDAANIVYGVNHDIYAPERHRIVTAASCTTNCLAPVVKVIHDNLRIKHGSITTIHNVT
CCCCCCEEEEECCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHCCCEEECCCEEEEEECC
NTQIIVDRPAKDLRRARSALNSLIPTTTGSATAITLIYPELTGRLNGHAVRVPLLNASLT
CCEEEEECCHHHHHHHHHHHHHHCCCCCCCCEEEEEEEECCCCCCCCCEEEEEEECCCHH
DCVFEVEQETTADEVNALFKAASEGPLNGILGYEERPLVSTDYTNDERSSIIDALSTMVI
HHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCCCCCCCEECCCCCCHHHHHHHHHHHHEE
NGTQVKVYAWYDNEMGYAHRLVDVACMVGDSL
CCCEEEEEEEECCCCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8378350 [H]