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The map label for this gene is sufS [H]

Identifier: 110679554

GI number: 110679554

Start: 2188512

End: 2189735

Strand: Direct

Name: sufS [H]

Synonym: RD1_2293

Alternate gene names: 110679554

Gene position: 2188512-2189735 (Clockwise)

Preceding gene: 110679553

Following gene: 110679555

Centisome position: 52.95

GC content: 62.09

Gene sequence:

>1224_bases
ATGAGACTGGATACAGATTTTATACGCGCGCAGTTTCCTGCGTTTCAGGTGCCCGCCCTGCAGGGGCAGGCGTTTTTCGA
AAACGCGGGCGGGTCCTATACCTGCAAACAGGTGATTGACCGGCTGACCCGGTTTTACACCGAACGCAAGGTGCAACCCT
ATGCGCCTTATGACGCCAGCACCCTGGCGGGCGCGGAGATGGACGAGGCGCGCACGCGCATGGCAGCACTCCTTGGTGTG
GATGCGGATGAGCTGAGCTTTGGGCCTTCGACGACACAAAACACCTATGTGCTGGCGCAGGCCTTTGCCGAATTCCTGCA
ACCGGGCGAGGCGATTGTCGTCACCAATCAGGACCATGAGGCCAACACCGGGCCATGGCGGCGTCTGGCCAAGCGCGGCA
TCGAGATCCGCGAATGGCGTGTGGACCCGGTCACCGGCCACCTTGACCCGGAGGACCTCGAAGCGCTGCTGGATGAAAAC
GTGCGCCTTGTGTGTTTTCCCCATTGTTCCAACGTGGTGGGAGAGGTCAACCCGGTGATCGAGATCACGGCACTGGCCCA
TGCCGCCGGGGCCTTTGTCTGTGTCGATGGGGTGTCTTATGCGCCGCATGGGTTTGTGGATGTCGGCTCGCTCGGGCCGG
ACATCTATCTGTTTTCGGCCTATAAAACCTATGGTCCCCATCAGGGTCTGATGGTGATCCGTCGCGTTCTTGGGGGGCTG
TTGCCCAATCAGGGCCATGAATTCAACGGTGACGCTTTGTACAAGCGGTTCACACCCGCCGGGCCAGATCACGCACAGGT
TGCTGCCTGCGCGGGCATGGCCGATTACGTTGACGCACTGTTTGATCATCACATTGGCGGACCTGCCAGCCCGACAGAGC
GGGGGCGTGCGGTGCATGACCTGATGCGCGACCATGAGGAAGCGCTGCTTGCGCCCCTGCTTGACGCGGTCAGCGGGCGC
AACGCGGTGCGTCTGATCGGCCCTGGCACGGCGGCTGGCCGCGCGCCCACGGTGGCGCTGGCTCTTGAGCGTCCGGGCGA
GGAAGTAGCGGCGGAGCTGTCGCGCCATGGGATCATGGCGGGCGGTGGTGATTTCTATGCGGGCCGCGCACTGTCGGCCA
TGGGGGTCGATGACAGGCTTGGCGTGCTGCGTTTGAGTTTCACGCACTACACGACCGCTGAGGATGTCGCACAGTTGATT
GACGCTTTGGACAAGGTATTGTGA

Upstream 100 bases:

>100_bases
AGGGCCATGGTTCACCCCATGGCCCTTTTTTATGGATGTGACGCAATGAAAGCCGTAAATGCGCTTGACGCTTTGCCCGG
GGCGGACAAGTTTGCCACTC

Downstream 100 bases:

>100_bases
GCGGCGCGACTGATCTAACTCTGAGGCCCGCGCGTAAAACCTGCAATAAATTCAGAAGGGTTACGGTTTGAGCACATCTC
CCGTTTTGGTCTGGTTCCGG

Product: aminotransferase, putative

Products: NA

Alternate protein names: Selenocysteine beta-lyase; SCL; Selenocysteine lyase; Selenocysteine reductase [H]

Number of amino acids: Translated: 407; Mature: 407

Protein sequence:

>407_residues
MRLDTDFIRAQFPAFQVPALQGQAFFENAGGSYTCKQVIDRLTRFYTERKVQPYAPYDASTLAGAEMDEARTRMAALLGV
DADELSFGPSTTQNTYVLAQAFAEFLQPGEAIVVTNQDHEANTGPWRRLAKRGIEIREWRVDPVTGHLDPEDLEALLDEN
VRLVCFPHCSNVVGEVNPVIEITALAHAAGAFVCVDGVSYAPHGFVDVGSLGPDIYLFSAYKTYGPHQGLMVIRRVLGGL
LPNQGHEFNGDALYKRFTPAGPDHAQVAACAGMADYVDALFDHHIGGPASPTERGRAVHDLMRDHEEALLAPLLDAVSGR
NAVRLIGPGTAAGRAPTVALALERPGEEVAAELSRHGIMAGGGDFYAGRALSAMGVDDRLGVLRLSFTHYTTAEDVAQLI
DALDKVL

Sequences:

>Translated_407_residues
MRLDTDFIRAQFPAFQVPALQGQAFFENAGGSYTCKQVIDRLTRFYTERKVQPYAPYDASTLAGAEMDEARTRMAALLGV
DADELSFGPSTTQNTYVLAQAFAEFLQPGEAIVVTNQDHEANTGPWRRLAKRGIEIREWRVDPVTGHLDPEDLEALLDEN
VRLVCFPHCSNVVGEVNPVIEITALAHAAGAFVCVDGVSYAPHGFVDVGSLGPDIYLFSAYKTYGPHQGLMVIRRVLGGL
LPNQGHEFNGDALYKRFTPAGPDHAQVAACAGMADYVDALFDHHIGGPASPTERGRAVHDLMRDHEEALLAPLLDAVSGR
NAVRLIGPGTAAGRAPTVALALERPGEEVAAELSRHGIMAGGGDFYAGRALSAMGVDDRLGVLRLSFTHYTTAEDVAQLI
DALDKVL
>Mature_407_residues
MRLDTDFIRAQFPAFQVPALQGQAFFENAGGSYTCKQVIDRLTRFYTERKVQPYAPYDASTLAGAEMDEARTRMAALLGV
DADELSFGPSTTQNTYVLAQAFAEFLQPGEAIVVTNQDHEANTGPWRRLAKRGIEIREWRVDPVTGHLDPEDLEALLDEN
VRLVCFPHCSNVVGEVNPVIEITALAHAAGAFVCVDGVSYAPHGFVDVGSLGPDIYLFSAYKTYGPHQGLMVIRRVLGGL
LPNQGHEFNGDALYKRFTPAGPDHAQVAACAGMADYVDALFDHHIGGPASPTERGRAVHDLMRDHEEALLAPLLDAVSGR
NAVRLIGPGTAAGRAPTVALALERPGEEVAAELSRHGIMAGGGDFYAGRALSAMGVDDRLGVLRLSFTHYTTAEDVAQLI
DALDKVL

Specific function: Cysteine desulfurases mobilize the sulfur from L- cysteine to yield L-alanine, an essential step in sulfur metabolism for biosynthesis of a variety of sulfur-containing biomolecules. Component of the suf operon, which is activated and required under speci

COG id: COG0520

COG function: function code E; Selenocysteine lyase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily [H]

Homologues:

Organism=Escherichia coli, GI1787970, Length=426, Percent_Identity=27.6995305164319, Blast_Score=124, Evalue=2e-29,
Organism=Escherichia coli, GI1789175, Length=420, Percent_Identity=27.1428571428571, Blast_Score=100, Evalue=3e-22,
Organism=Escherichia coli, GI48994898, Length=171, Percent_Identity=28.6549707602339, Blast_Score=74, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6319831, Length=204, Percent_Identity=24.5098039215686, Blast_Score=66, Evalue=8e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR020578
- InterPro:   IPR010970
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.8.1.7; =4.4.1.16 [H]

Molecular weight: Translated: 43896; Mature: 43896

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLDTDFIRAQFPAFQVPALQGQAFFENAGGSYTCKQVIDRLTRFYTERKVQPYAPYDAS
CCCCHHHHHHCCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCH
TLAGAEMDEARTRMAALLGVDADELSFGPSTTQNTYVLAQAFAEFLQPGEAIVVTNQDHE
HHCCCHHHHHHHHHHHHHCCCHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCC
ANTGPWRRLAKRGIEIREWRVDPVTGHLDPEDLEALLDENVRLVCFPHCSNVVGEVNPVI
CCCCHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHCCCCEEEEECCCCCHHHCCCCCE
EITALAHAAGAFVCVDGVSYAPHGFVDVGSLGPDIYLFSAYKTYGPHQGLMVIRRVLGGL
EEEHHHHHCCCEEEECCCCCCCCCCEECCCCCCCEEEEEEHHHCCCCHHHHHHHHHHHHC
LPNQGHEFNGDALYKRFTPAGPDHAQVAACAGMADYVDALFDHHIGGPASPTERGRAVHD
CCCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
LMRDHEEALLAPLLDAVSGRNAVRLIGPGTAAGRAPTVALALERPGEEVAAELSRHGIMA
HHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCEE
GGGDFYAGRALSAMGVDDRLGVLRLSFTHYTTAEDVAQLIDALDKVL
CCCCCCCCCHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRLDTDFIRAQFPAFQVPALQGQAFFENAGGSYTCKQVIDRLTRFYTERKVQPYAPYDAS
CCCCHHHHHHCCCCCCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCH
TLAGAEMDEARTRMAALLGVDADELSFGPSTTQNTYVLAQAFAEFLQPGEAIVVTNQDHE
HHCCCHHHHHHHHHHHHHCCCHHHCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEECCCCC
ANTGPWRRLAKRGIEIREWRVDPVTGHLDPEDLEALLDENVRLVCFPHCSNVVGEVNPVI
CCCCHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHCCCCEEEEECCCCCHHHCCCCCE
EITALAHAAGAFVCVDGVSYAPHGFVDVGSLGPDIYLFSAYKTYGPHQGLMVIRRVLGGL
EEEHHHHHCCCEEEECCCCCCCCCCEECCCCCCCEEEEEEHHHCCCCHHHHHHHHHHHHC
LPNQGHEFNGDALYKRFTPAGPDHAQVAACAGMADYVDALFDHHIGGPASPTERGRAVHD
CCCCCCCCCCCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHH
LMRDHEEALLAPLLDAVSGRNAVRLIGPGTAAGRAPTVALALERPGEEVAAELSRHGIMA
HHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCCCCEEEEEECCCCHHHHHHHHHCCCEE
GGGDFYAGRALSAMGVDDRLGVLRLSFTHYTTAEDVAQLIDALDKVL
CCCCCCCCCHHHHCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA