Click here to switch to the map view.

The map label for this gene is betT [C]

Identifier: 110679553

GI number: 110679553

Start: 2186716

End: 2188389

Strand: Direct

Name: betT [C]

Synonym: RD1_2292

Alternate gene names: 110679553

Gene position: 2186716-2188389 (Clockwise)

Preceding gene: 110679551

Following gene: 110679554

Centisome position: 52.91

GC content: 57.83

Gene sequence:

>1674_bases
ATGGCACTAAAACCCCCATTATCCGATCTGCCGATCAAAACGGCAAATGCGGGATTTTACCGCGGCTTCAGCGTCGATGT
GACGGTGGCCAGTAAAATCATCATCAGCGTATTGGTCGTCTGGTGTATCTTCTGGCCGACGCAGTCCGGCCGGGTCCTCA
GTGATCTCAACAGCGTGATCCTTGCCAATGCGGCAGGCTGGTACATCTGGACCGTCGCATTCTTTATCATCATATGTCTC
GGGTTGGCGATATGGCCGACAGCGGGTCGAATGAACCTTGGCGTGGAAGGTGAAAAGCCCGAATTCTCCAATTTTTCGTG
GTTTTCGATGATGTTTGGTGCGGGTATCGGCGTTGGCATGCTGACCTGGGCCGTGGCCGAACCGGTTGCGCATTTCGGCA
GTAACCCTGAGACAATTCAGGGCCTTACCACGGGCGGCGCTGCGGACAACGTGCGTATGGCCTATAAGTGGTCCTTCCTG
CACTGGGGCCTTGGCGCGTGGGCCTGTTATGCGGTCTGCGGTCTGTCACTTGCGTTTTTCAGCTATCGGCGCGGATTGCC
GCTGACGATCCGCTCGGCACTGACCCCACTCTTTGGCAAGGCCTTGTCGGGTAAGCTGGGCCATGTGATCGACATCGTCG
CGGTGGTTGCAACCATCCTGGGCGTGGCGCAAACGCTTGGCTTTGGTGTCGAACAATTCGTGGCGGGTCTGACCCGGATC
GGCATCGGCGGTCTGGTCTATGAGGATGGCGGCGCCACCTTCGTCGGTATCATCGTCGCGCTGCTGGTCATCATGGGAGC
ATCGACGCTCTCGGCGCTTTCCGGTGTGGGCAAGGGCATCAAATGGCTCTCCAACATCAACATGGTGCTGTCGATTTTCC
TTCTCGGCTTCTTCATCCTCTTCGGGGCGACTTGGTTTGGCGCATCTGCGATGTTCCTTGGGCTGATCGACTATCTGCTG
GCCTTGCCGCAGATGAGCTTCAACGTCTGGAAATCTGACGGTGTCGAGGGATCAGAAGCCTTCCTGCTGGCACAGTGGCA
AGGGTGGTGGCCGGTGTTCTACTGGGCCTGGTGGATCGCATTTGCACCTTTCGTGGGCTTGTTCCTTGCGCGGATCTCGC
GCGGTCGCTCCATCCGTGAATTCGTGCTGGGTGCGATGATCGTGCCATCGCTGATGTGCTTTGTCTGGTTCGCCTGGGCT
GGTGGTACGGCGATTGATCTTGAATTGAACGGGGGCGCGAATGGTGTAATCTTCGATGCCGCCAATGGTGACAAGATCTT
TGCGATGACCGAATTCATGCTGGCACCGATTGCGGATATACTGGCATGGGGCATGGCCTTTCTGATCGTTGTTCTGCTGA
TGACGTTCCTCGTGACATCTGCGGACTCTGCGGTGCTGATCGTGAACACGATCAATGCTGCCGGGGACGAGGGCCCGAAA
GCACGCCCGCATATCCTGTTCTGGGGGGCCGCTTTGGGGCTCGTGGTTGCAGGGCTGCTCTTGTCGGGCGGAACATCCGC
CATTCAAACCGCCATGGTCATCGGTGCCCTGCCGTTTTCGATCGTGATGGTGCTGATGTGTATTTCCCTGATCAAGGCGA
TTTACAACGATGGCCGCCGTGAAGCTGCGGGCATTCCGGCGACCATGGAGCCGGACGCAACCGCAGCTGAGTAA

Upstream 100 bases:

>100_bases
AATGCGGCGTTTTGAGGGGCAAAACTGACGTTTCTCTGCATTGTCTTTCGTGCCGTTCAAGTAGCTTGAAGAAATAATAA
CGAACAGGGAACAGTAAAAA

Downstream 100 bases:

>100_bases
TGCGCTGACGTCATTTTAAGAAAGGGCCATGGTTCACCCCATGGCCCTTTTTTATGGATGTGACGCAATGAAAGCCGTAA
ATGCGCTTGACGCTTTGCCC

Product: glycine betaine transporter, putative

Products: Proton [Cytoplasm]; choline [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 557; Mature: 556

Protein sequence:

>557_residues
MALKPPLSDLPIKTANAGFYRGFSVDVTVASKIIISVLVVWCIFWPTQSGRVLSDLNSVILANAAGWYIWTVAFFIIICL
GLAIWPTAGRMNLGVEGEKPEFSNFSWFSMMFGAGIGVGMLTWAVAEPVAHFGSNPETIQGLTTGGAADNVRMAYKWSFL
HWGLGAWACYAVCGLSLAFFSYRRGLPLTIRSALTPLFGKALSGKLGHVIDIVAVVATILGVAQTLGFGVEQFVAGLTRI
GIGGLVYEDGGATFVGIIVALLVIMGASTLSALSGVGKGIKWLSNINMVLSIFLLGFFILFGATWFGASAMFLGLIDYLL
ALPQMSFNVWKSDGVEGSEAFLLAQWQGWWPVFYWAWWIAFAPFVGLFLARISRGRSIREFVLGAMIVPSLMCFVWFAWA
GGTAIDLELNGGANGVIFDAANGDKIFAMTEFMLAPIADILAWGMAFLIVVLLMTFLVTSADSAVLIVNTINAAGDEGPK
ARPHILFWGAALGLVVAGLLLSGGTSAIQTAMVIGALPFSIVMVLMCISLIKAIYNDGRREAAGIPATMEPDATAAE

Sequences:

>Translated_557_residues
MALKPPLSDLPIKTANAGFYRGFSVDVTVASKIIISVLVVWCIFWPTQSGRVLSDLNSVILANAAGWYIWTVAFFIIICL
GLAIWPTAGRMNLGVEGEKPEFSNFSWFSMMFGAGIGVGMLTWAVAEPVAHFGSNPETIQGLTTGGAADNVRMAYKWSFL
HWGLGAWACYAVCGLSLAFFSYRRGLPLTIRSALTPLFGKALSGKLGHVIDIVAVVATILGVAQTLGFGVEQFVAGLTRI
GIGGLVYEDGGATFVGIIVALLVIMGASTLSALSGVGKGIKWLSNINMVLSIFLLGFFILFGATWFGASAMFLGLIDYLL
ALPQMSFNVWKSDGVEGSEAFLLAQWQGWWPVFYWAWWIAFAPFVGLFLARISRGRSIREFVLGAMIVPSLMCFVWFAWA
GGTAIDLELNGGANGVIFDAANGDKIFAMTEFMLAPIADILAWGMAFLIVVLLMTFLVTSADSAVLIVNTINAAGDEGPK
ARPHILFWGAALGLVVAGLLLSGGTSAIQTAMVIGALPFSIVMVLMCISLIKAIYNDGRREAAGIPATMEPDATAAE
>Mature_556_residues
ALKPPLSDLPIKTANAGFYRGFSVDVTVASKIIISVLVVWCIFWPTQSGRVLSDLNSVILANAAGWYIWTVAFFIIICLG
LAIWPTAGRMNLGVEGEKPEFSNFSWFSMMFGAGIGVGMLTWAVAEPVAHFGSNPETIQGLTTGGAADNVRMAYKWSFLH
WGLGAWACYAVCGLSLAFFSYRRGLPLTIRSALTPLFGKALSGKLGHVIDIVAVVATILGVAQTLGFGVEQFVAGLTRIG
IGGLVYEDGGATFVGIIVALLVIMGASTLSALSGVGKGIKWLSNINMVLSIFLLGFFILFGATWFGASAMFLGLIDYLLA
LPQMSFNVWKSDGVEGSEAFLLAQWQGWWPVFYWAWWIAFAPFVGLFLARISRGRSIREFVLGAMIVPSLMCFVWFAWAG
GTAIDLELNGGANGVIFDAANGDKIFAMTEFMLAPIADILAWGMAFLIVVLLMTFLVTSADSAVLIVNTINAAGDEGPKA
RPHILFWGAALGLVVAGLLLSGGTSAIQTAMVIGALPFSIVMVLMCISLIKAIYNDGRREAAGIPATMEPDATAAE

Specific function: High-Affinity Uptake Of Choline Driven By A Proton- Motive Force. [C]

COG id: COG1292

COG function: function code M; Choline-glycine betaine transporter

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the BCCT transporter (TC 2.A.15) family [H]

Homologues:

Organism=Escherichia coli, GI1786506, Length=497, Percent_Identity=38.2293762575453, Blast_Score=285, Evalue=8e-78,
Organism=Escherichia coli, GI1786224, Length=454, Percent_Identity=29.5154185022026, Blast_Score=131, Evalue=1e-31,
Organism=Escherichia coli, GI1788102, Length=484, Percent_Identity=26.8595041322314, Blast_Score=125, Evalue=6e-30,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000060
- InterPro:   IPR018093 [H]

Pfam domain/function: PF02028 BCCT [H]

EC number: NA

Molecular weight: Translated: 59419; Mature: 59288

Theoretical pI: Translated: 5.74; Mature: 5.74

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.4 %Met     (Mature Protein)
4.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ALKPPLSDLPIKTANAGFYRGFSVDVTVASKIIISVLVVWCIFWPTQSGRVLSDLNSVI
CCCCCCCCCCCCCCCCCEECCCEEEHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
LANAAGWYIWTVAFFIIICLGLAIWPTAGRMNLGVEGEKPEFSNFSWFSMMFGAGIGVGM
HHCCCHHHHHHHHHHHHHHHHHHHCCCCCCEECCCCCCCCCCCCCHHHHHHHHCCCHHHH
LTWAVAEPVAHFGSNPETIQGLTTGGAADNVRMAYKWSFLHWGLGAWACYAVCGLSLAFF
HHHHHHHHHHHHCCCCCCEECEECCCCCCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHH
SYRRGLPLTIRSALTPLFGKALSGKLGHVIDIVAVVATILGVAQTLGFGVEQFVAGLTRI
HHHCCCCEEHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
GIGGLVYEDGGATFVGIIVALLVIMGASTLSALSGVGKGIKWLSNINMVLSIFLLGFFIL
CCCCEEEECCCCHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGATWFGASAMFLGLIDYLLALPQMSFNVWKSDGVEGSEAFLLAQWQGWWPVFYWAWWIA
HHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHH
FAPFVGLFLARISRGRSIREFVLGAMIVPSLMCFVWFAWAGGTAIDLELNGGANGVIFDA
HHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCCCEEEEEC
ANGDKIFAMTEFMLAPIADILAWGMAFLIVVLLMTFLVTSADSAVLIVNTINAAGDEGPK
CCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEECCCCCCCCCC
ARPHILFWGAALGLVVAGLLLSGGTSAIQTAMVIGALPFSIVMVLMCISLIKAIYNDGRR
CCCCEEEHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCH
EAAGIPATMEPDATAAE
HHCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: Proton [Periplasm]; choline [Periplasm] [C]

Specific reaction: Proton [Periplasm] + choline [Periplasm] = Proton [Cytoplasm] + choline [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]