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The map label for this gene is siaT [H]

Identifier: 110679449

GI number: 110679449

Start: 2072676

End: 2074055

Strand: Reverse

Name: siaT [H]

Synonym: RD1_2175

Alternate gene names: 110679449

Gene position: 2074055-2072676 (Counterclockwise)

Preceding gene: 110679450

Following gene: 110679448

Centisome position: 50.18

GC content: 58.62

Gene sequence:

>1380_bases
GTGCATTTCCGAGCTGTTCAAGGACGTGCTGCGTCTGAAAGGTCACACCATCTGATGCCCTATGAACTGATCGCCACGCT
GATGTTCTCGACCATGATGCTGATGCTGCTGACGGGACAGCGGGTCTTTGGCGCGATTGGTTTTGTGGCTGTGGTTGCCG
CCCTACTGCTCTGGGGGGATCGGGGCGGGTATGATCTGGGCTTTTCAGCGGCGATGAAGCTGATGAAGTGGTATCCGCTG
CTGACCCTGCCGATGTTCATTTTCATGGGCTACGTGCTGTCTGAAAGTAAAATCGCAGATGACCTCTATCGCATGTTCCA
CGTCTGGATGGGCGGCGTGCGCGGCGGGCTTGCCATCGGGACAATCGGGTTGATGGTGCTGATTTCCGCCATGAACGGGC
TGTCGGTTGCGGGCATGGCGATTGGCGCGACCATTGCGCTGCCCGAATTGCTGAAACGTGGCTATGACAAACGGATGGTG
ACGGGTGTTATTCAGGCCGGATCGTCCCTTGGGATATTGGTGCCACCCTCGGTGGTGCTGGTGCTTTACGCGATGATCGC
GCGGCAACCCGTGGGGCAATTGTGGCTTGCGGGTGTCATTCCGGGGCTGATGATGGCCGCGCTTTTCATCCTCTACATCG
CGCTGCGGTGTCGGATAAACCCCACTCTTGGCCCCGCGCTGGCGGCGGAGGAGCGCGACATTCCCCGCGCTGAAAAGATG
CGCCTGTTGCGCGCGGGTCTGCTGCCACTGACGATCTTTGCCGTGATGATGGTGCCTTTTGTCAACGGCTGGACCTCGCT
GGTCGAAAGCTCTGCCATCGGAGCGCTGGCCGCCTTCCTTGCCGCCGTGTTCAAGGGCCGCATGACGCGCGAAGTCTTTG
AGAATTCGGTGCGCAATACGCTGGGCATCACCTGCATGTTCATGTGGATCATCCTCGCCGCGCTCGCCTTTGGCGCGGTC
TTTGACGGGCTGGGCGCTGTCAAAGCCATAGAGAGCCTGTTCACCGAACGCTTGAACCTGAACCCATGGATGATCCTGAT
CCTGATGCAACTCAGCTTTATCCTGATGGGCACCTTTCTGGATGACACCGCGATGCTGGTTATCGTGGCCCCGCTTTACG
TGCCGCTCGTGGGCGCGCTGGGGTTCGATCTGATTTGGTACGGCATCCTTTACACGATCACCACGCAGATCGCCTATATG
ACCCCGCCCTTTGGTTACAATCTGTTCCTGATGCGCGCCATGGCCCCGCCCGAAATCTCCCTGCGCGACATCTATGCCTC
CATCACGCCTTTTGTGTTGATCATGGCGGGCGCACTGGCGCTGGTGATGCTTTTTCCCGGCCTTGCGCTTTGGCTGCCGG
AGTATGTTTATGGAAATTAA

Upstream 100 bases:

>100_bases
AGGAAGTCGGCCGGATGGAGCGATCATCGTCCGCGTGGCGTCCCCTTATGTGGCCGATCAAGGCCGTGATGATCGTCGGG
TTTTTCCTGATGCTGCTGCA

Downstream 100 bases:

>100_bases
CCAACCAAGATCAGGCCAACCTGACATAACCCAATAAGGAGAACCACTATGACAACCAGACGTAAGTTTATCCAAGGGGC
CGCCGTGGCCGCCCCCGCCG

Product: TRAP dicarboxylate transporter, DctM subunit, putative

Products: NA

Alternate protein names: N-acetylneuraminic acid permease; N-acetylneuraminic acid transporter; Neu5Ac permease [H]

Number of amino acids: Translated: 459; Mature: 459

Protein sequence:

>459_residues
MHFRAVQGRAASERSHHLMPYELIATLMFSTMMLMLLTGQRVFGAIGFVAVVAALLLWGDRGGYDLGFSAAMKLMKWYPL
LTLPMFIFMGYVLSESKIADDLYRMFHVWMGGVRGGLAIGTIGLMVLISAMNGLSVAGMAIGATIALPELLKRGYDKRMV
TGVIQAGSSLGILVPPSVVLVLYAMIARQPVGQLWLAGVIPGLMMAALFILYIALRCRINPTLGPALAAEERDIPRAEKM
RLLRAGLLPLTIFAVMMVPFVNGWTSLVESSAIGALAAFLAAVFKGRMTREVFENSVRNTLGITCMFMWIILAALAFGAV
FDGLGAVKAIESLFTERLNLNPWMILILMQLSFILMGTFLDDTAMLVIVAPLYVPLVGALGFDLIWYGILYTITTQIAYM
TPPFGYNLFLMRAMAPPEISLRDIYASITPFVLIMAGALALVMLFPGLALWLPEYVYGN

Sequences:

>Translated_459_residues
MHFRAVQGRAASERSHHLMPYELIATLMFSTMMLMLLTGQRVFGAIGFVAVVAALLLWGDRGGYDLGFSAAMKLMKWYPL
LTLPMFIFMGYVLSESKIADDLYRMFHVWMGGVRGGLAIGTIGLMVLISAMNGLSVAGMAIGATIALPELLKRGYDKRMV
TGVIQAGSSLGILVPPSVVLVLYAMIARQPVGQLWLAGVIPGLMMAALFILYIALRCRINPTLGPALAAEERDIPRAEKM
RLLRAGLLPLTIFAVMMVPFVNGWTSLVESSAIGALAAFLAAVFKGRMTREVFENSVRNTLGITCMFMWIILAALAFGAV
FDGLGAVKAIESLFTERLNLNPWMILILMQLSFILMGTFLDDTAMLVIVAPLYVPLVGALGFDLIWYGILYTITTQIAYM
TPPFGYNLFLMRAMAPPEISLRDIYASITPFVLIMAGALALVMLFPGLALWLPEYVYGN
>Mature_459_residues
MHFRAVQGRAASERSHHLMPYELIATLMFSTMMLMLLTGQRVFGAIGFVAVVAALLLWGDRGGYDLGFSAAMKLMKWYPL
LTLPMFIFMGYVLSESKIADDLYRMFHVWMGGVRGGLAIGTIGLMVLISAMNGLSVAGMAIGATIALPELLKRGYDKRMV
TGVIQAGSSLGILVPPSVVLVLYAMIARQPVGQLWLAGVIPGLMMAALFILYIALRCRINPTLGPALAAEERDIPRAEKM
RLLRAGLLPLTIFAVMMVPFVNGWTSLVESSAIGALAAFLAAVFKGRMTREVFENSVRNTLGITCMFMWIILAALAFGAV
FDGLGAVKAIESLFTERLNLNPWMILILMQLSFILMGTFLDDTAMLVIVAPLYVPLVGALGFDLIWYGILYTITTQIAYM
TPPFGYNLFLMRAMAPPEISLRDIYASITPFVLIMAGALALVMLFPGLALWLPEYVYGN

Specific function: Part of the tripartite ATP-independent periplasmic (TRAP) transport system siaPT involved in the uptake of sialic acid [H]

COG id: COG4664

COG function: function code Q; TRAP-type mannitol/chloroaromatic compound transport system, large permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the TRAP transporter large permease family [H]

Homologues:

Organism=Escherichia coli, GI48994950, Length=386, Percent_Identity=22.279792746114, Blast_Score=72, Evalue=6e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010656
- InterPro:   IPR007387
- InterPro:   IPR004681 [H]

Pfam domain/function: PF06808 DctM; PF04290 DctQ [H]

EC number: NA

Molecular weight: Translated: 50200; Mature: 50200

Theoretical pI: Translated: 9.30; Mature: 9.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
7.4 %Met     (Translated Protein)
7.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
7.4 %Met     (Mature Protein)
7.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure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HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]