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The map label for this gene is ilvC [H]

Identifier: 110679241

GI number: 110679241

Start: 1867283

End: 1868305

Strand: Reverse

Name: ilvC [H]

Synonym: RD1_1954

Alternate gene names: 110679241

Gene position: 1868305-1867283 (Counterclockwise)

Preceding gene: 110679245

Following gene: 110679240

Centisome position: 45.2

GC content: 56.79

Gene sequence:

>1023_bases
ATGCGCGTCTATTACGACAGAGATTGCGATGTAAACCTGATCAAGGACATGAAAGTAGCCATTCTTGGCTATGGCAGCCA
AGGTCACGCACATGCGTTGAACCTGCGCGATTCAGGGGCCAAGAACCTCGCCGTTGCGCTGCGCGAGGGATCTGCCTCTG
CCGCAAAGGCCGAAGGCGAAGGCCTGCAGGTCATGGGCATTGCCGAAGCCGCCGCATGGGCCGACCTGATCATGTTCACC
ATGCCCGATGAGCTTCAGGCCGAGACCTACAAGAAATACGTCCATGACAACATCCGCGAAGGGGCTGCAATCGCTTTCGC
GCATGGGCTTAACGTCCACTTTGGCCTGATTGAACCCAAGGAAGGCATCGACGTGATCATGATGGCGCCAAAGGGCCCCG
GTCACACGGTACGCGGTGAATATACCAAAGGCGGTGGTGTTCCCTGCCTTGTTGCTGTTGACAAAGACGCCTCCGGCCGC
GCGCTGGAAATCGGGCTGTCCTATTGCTCTGCCATTGGCGGTGGTCGCTCGGGCATCATCGAAACCAACTTCCGCGAGGA
ATGCGAAACCGACCTCTTTGGCGAACAGGCCGTTCTGTGCGGTGGCCTCGTTGAACTGATCCGCATGGGCTTTGAGACCC
TTGTCGAGGCAGGCTACGCGCCCGAAATGGCCTATTTCGAATGCCTGCACGAGGTGAAACTGATCGTTGATCTGATCTAT
GAAGGCGGCATCGCCAACATGAACTACTCGATCTCGAACACGGCGGAGTATGGCGAATATGTCTCCGGCCCGCGCGTCTT
GCCCTATGACGAGACCAAAGCGCGCATGAAGGCGATCCTGACGGACATTCAGAACGGCAAATTCGTGCGTGACTTCATGC
AGGAAAATGCCGTAGGCCAGCCACACTTCAAAGCGACACGTCGCATCAATGACGAACACCAGATCGAAGCAACCGGCGAA
ACCCTGCGCGGCATGATGCCCTGGATCTCCGCTGGCAAGATGGTTGATAAGTCCAAGAACTAA

Upstream 100 bases:

>100_bases
TGCAAAAAACCAACAATTTCCAGAGCCTCAATCGCTGGTATTACGGGGATATGCGCGTATTGTGCACCCCAGCATAAACC
AGACAGAAGGAGCGCCCGAC

Downstream 100 bases:

>100_bases
GCGTTCAACAGCTTTGAACCACGATCACCCCGGCGCAGCACGTCGGGGTGACGCTTTTACGGTAGAAAGAACCCGTGTCA
CAACACCCCCAGATCACCGC

Product: ketol-acid reductoisomerase

Products: NA

Alternate protein names: Acetohydroxy-acid isomeroreductase; Alpha-keto-beta-hydroxylacil reductoisomerase [H]

Number of amino acids: Translated: 340; Mature: 340

Protein sequence:

>340_residues
MRVYYDRDCDVNLIKDMKVAILGYGSQGHAHALNLRDSGAKNLAVALREGSASAAKAEGEGLQVMGIAEAAAWADLIMFT
MPDELQAETYKKYVHDNIREGAAIAFAHGLNVHFGLIEPKEGIDVIMMAPKGPGHTVRGEYTKGGGVPCLVAVDKDASGR
ALEIGLSYCSAIGGGRSGIIETNFREECETDLFGEQAVLCGGLVELIRMGFETLVEAGYAPEMAYFECLHEVKLIVDLIY
EGGIANMNYSISNTAEYGEYVSGPRVLPYDETKARMKAILTDIQNGKFVRDFMQENAVGQPHFKATRRINDEHQIEATGE
TLRGMMPWISAGKMVDKSKN

Sequences:

>Translated_340_residues
MRVYYDRDCDVNLIKDMKVAILGYGSQGHAHALNLRDSGAKNLAVALREGSASAAKAEGEGLQVMGIAEAAAWADLIMFT
MPDELQAETYKKYVHDNIREGAAIAFAHGLNVHFGLIEPKEGIDVIMMAPKGPGHTVRGEYTKGGGVPCLVAVDKDASGR
ALEIGLSYCSAIGGGRSGIIETNFREECETDLFGEQAVLCGGLVELIRMGFETLVEAGYAPEMAYFECLHEVKLIVDLIY
EGGIANMNYSISNTAEYGEYVSGPRVLPYDETKARMKAILTDIQNGKFVRDFMQENAVGQPHFKATRRINDEHQIEATGE
TLRGMMPWISAGKMVDKSKN
>Mature_340_residues
MRVYYDRDCDVNLIKDMKVAILGYGSQGHAHALNLRDSGAKNLAVALREGSASAAKAEGEGLQVMGIAEAAAWADLIMFT
MPDELQAETYKKYVHDNIREGAAIAFAHGLNVHFGLIEPKEGIDVIMMAPKGPGHTVRGEYTKGGGVPCLVAVDKDASGR
ALEIGLSYCSAIGGGRSGIIETNFREECETDLFGEQAVLCGGLVELIRMGFETLVEAGYAPEMAYFECLHEVKLIVDLIY
EGGIANMNYSISNTAEYGEYVSGPRVLPYDETKARMKAILTDIQNGKFVRDFMQENAVGQPHFKATRRINDEHQIEATGE
TLRGMMPWISAGKMVDKSKN

Specific function: Valine and isoleucine biosynthesis; second step. [C]

COG id: COG0059

COG function: function code EH; Ketol-acid reductoisomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ketol-acid reductoisomerase family [H]

Homologues:

Organism=Escherichia coli, GI1790210, Length=252, Percent_Identity=37.3015873015873, Blast_Score=135, Evalue=3e-33,
Organism=Saccharomyces cerevisiae, GI6323387, Length=348, Percent_Identity=29.5977011494253, Blast_Score=112, Evalue=6e-26,

Paralogues:

None

Copy number: 160 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 1420 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR008927
- InterPro:   IPR013023
- InterPro:   IPR000506
- InterPro:   IPR013328
- InterPro:   IPR013116 [H]

Pfam domain/function: PF01450 IlvC; PF07991 IlvN [H]

EC number: =1.1.1.86 [H]

Molecular weight: Translated: 37056; Mature: 37056

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
4.4 %Met     (Mature Protein)
6.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRVYYDRDCDVNLIKDMKVAILGYGSQGHAHALNLRDSGAKNLAVALREGSASAAKAEGE
CCEEECCCCCCCHHCCCEEEEEEECCCCCEEEEECCCCCCCEEEEEEECCCCCCCCCCCC
GLQVMGIAEAAAWADLIMFTMPDELQAETYKKYVHDNIREGAAIAFAHGLNVHFGLIEPK
CEEEEEHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHCCCCEEEEEECCEEEEEEECCC
EGIDVIMMAPKGPGHTVRGEYTKGGGVPCLVAVDKDASGRALEIGLSYCSAIGGGRSGII
CCCEEEEECCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEHHHHHHHCCCCCCCEE
ETNFREECETDLFGEQAVLCGGLVELIRMGFETLVEAGYAPEMAYFECLHEVKLIVDLIY
ECCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
EGGIANMNYSISNTAEYGEYVSGPRVLPYDETKARMKAILTDIQNGKFVRDFMQENAVGQ
CCCCCCCCEECCCCHHHHHHCCCCEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCC
PHFKATRRINDEHQIEATGETLRGMMPWISAGKMVDKSKN
CCHHHHHCCCCCCEEEECHHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MRVYYDRDCDVNLIKDMKVAILGYGSQGHAHALNLRDSGAKNLAVALREGSASAAKAEGE
CCEEECCCCCCCHHCCCEEEEEEECCCCCEEEEECCCCCCCEEEEEEECCCCCCCCCCCC
GLQVMGIAEAAAWADLIMFTMPDELQAETYKKYVHDNIREGAAIAFAHGLNVHFGLIEPK
CEEEEEHHHHHHHHHHHEEECCCHHHHHHHHHHHHHHHCCCCEEEEEECCEEEEEEECCC
EGIDVIMMAPKGPGHTVRGEYTKGGGVPCLVAVDKDASGRALEIGLSYCSAIGGGRSGII
CCCEEEEECCCCCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEEHHHHHHHCCCCCCCEE
ETNFREECETDLFGEQAVLCGGLVELIRMGFETLVEAGYAPEMAYFECLHEVKLIVDLIY
ECCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
EGGIANMNYSISNTAEYGEYVSGPRVLPYDETKARMKAILTDIQNGKFVRDFMQENAVGQ
CCCCCCCCEECCCCHHHHHHCCCCEECCCCHHHHHHHHHHHHCCCCHHHHHHHHHCCCCC
PHFKATRRINDEHQIEATGETLRGMMPWISAGKMVDKSKN
CCHHHHHCCCCCCEEEECHHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA