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The map label for this gene is dnaE2 [H]

Identifier: 110679213

GI number: 110679213

Start: 1836635

End: 1837030

Strand: Reverse

Name: dnaE2 [H]

Synonym: RD1_1924

Alternate gene names: 110679213

Gene position: 1837030-1836635 (Counterclockwise)

Preceding gene: 110679216

Following gene: 110679206

Centisome position: 44.45

GC content: 58.59

Gene sequence:

>396_bases
ATGCAGGTTATCACGTCTCACCCCGCCTCGCCGGTCAATGCGAAACCCGCTGGGAAGTGGCCCAGCCCCCCCGCCTGCCT
TGTCGCGCGGCAACTGACACAGCCACCGCAAAATGCACGGGTTGCCGTGGCCGGCATCGTCATTTTACGCCAGCGTCCCG
GCACGGCAAAGGGTGTTATCTTTCTCACGCTGGAGGATGAGACCGGCGTTGTGAATGTGATTGTCTGGCGGAATATCTAT
GAAAAATTCCGCCGCGCGGTGATCGCGGGGCGGATGTTGCGCGTTACAGGCAGGCTTCAGCGCGCCCATTCCGTCACCCA
TGTTCTGGCGGAAAAGATCGAGGATTTATCGCCTTTGCTGGATGGTCTTGTGCAGGAAAACAAGGCATCTGAGTAA

Upstream 100 bases:

>100_bases
TTCAATCCGTTCTGTGTCGGCATATAGAGCGCGGGCGCCTGTTTTACGACCCCCTTCGCAGAGGATTGTTTTTGATTTCT
TTTGTTCTATATTTGTTCTC

Downstream 100 bases:

>100_bases
CCCCCTCCCCGGCACAAAAAAGGGCGCTGCAAGAGCGCCCCTTTTACCACTTTTTCCGATCCGATCACTCGGCGAGGGAC
AGCGCCACGAACCGTGGATC

Product: DNA polymerase III alpha subunit, putative

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 131; Mature: 131

Protein sequence:

>131_residues
MQVITSHPASPVNAKPAGKWPSPPACLVARQLTQPPQNARVAVAGIVILRQRPGTAKGVIFLTLEDETGVVNVIVWRNIY
EKFRRAVIAGRMLRVTGRLQRAHSVTHVLAEKIEDLSPLLDGLVQENKASE

Sequences:

>Translated_131_residues
MQVITSHPASPVNAKPAGKWPSPPACLVARQLTQPPQNARVAVAGIVILRQRPGTAKGVIFLTLEDETGVVNVIVWRNIY
EKFRRAVIAGRMLRVTGRLQRAHSVTHVLAEKIEDLSPLLDGLVQENKASE
>Mature_131_residues
MQVITSHPASPVNAKPAGKWPSPPACLVARQLTQPPQNARVAVAGIVILRQRPGTAKGVIFLTLEDETGVVNVIVWRNIY
EKFRRAVIAGRMLRVTGRLQRAHSVTHVLAEKIEDLSPLLDGLVQENKASE

Specific function: DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase [H]

COG id: COG0587

COG function: function code L; DNA polymerase III, alpha subunit

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DNA polymerase type-C family. DnaE2 subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011708
- InterPro:   IPR023073
- InterPro:   IPR012340
- InterPro:   IPR004365
- InterPro:   IPR004013
- InterPro:   IPR003141
- InterPro:   IPR016195
- InterPro:   IPR004805 [H]

Pfam domain/function: PF07733 DNA_pol3_alpha; PF02811 PHP; PF01336 tRNA_anti [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 14331; Mature: 14331

Theoretical pI: Translated: 11.02; Mature: 11.02

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVITSHPASPVNAKPAGKWPSPPACLVARQLTQPPQNARVAVAGIVILRQRPGTAKGVI
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEEEEEEECCCCCCCCEE
FLTLEDETGVVNVIVWRNIYEKFRRAVIAGRMLRVTGRLQRAHSVTHVLAEKIEDLSPLL
EEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DGLVQENKASE
HHHHHHCCCCC
>Mature Secondary Structure
MQVITSHPASPVNAKPAGKWPSPPACLVARQLTQPPQNARVAVAGIVILRQRPGTAKGVI
CCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCEEEEEEEEEEECCCCCCCCEE
FLTLEDETGVVNVIVWRNIYEKFRRAVIAGRMLRVTGRLQRAHSVTHVLAEKIEDLSPLL
EEEECCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DGLVQENKASE
HHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA