Click here to switch to the map view.

The map label for this gene is hflK [H]

Identifier: 110679209

GI number: 110679209

Start: 1832702

End: 1833865

Strand: Direct

Name: hflK [H]

Synonym: RD1_1920

Alternate gene names: 110679209

Gene position: 1832702-1833865 (Clockwise)

Preceding gene: 110679208

Following gene: 110679210

Centisome position: 44.34

GC content: 60.91

Gene sequence:

>1164_bases
ATGGCTGGCAACAATGGCGGCCCCTGGGGGGGCGGCGGAAATTCGGGCAATGACAGGCCGAACGGCGGTTCGGGCGGCGG
AAATCGTGGATCAGGCGGCGGTGGCCCGCGCGGTCCCGGCGGCGAAGGGCCGCAAATTCCCGAGATAGATGAACTGGTCA
AGAAGGGCCAGGAACGTCTGCGCGTTCTGATGGGCGGCAAAGGTGGAAATGGGACCGGCGGTGGTGCTGGCGGCGGTGGC
GGTGGCGGACCCGCGCTGACGCGTGGCACGGTAGGGCTGGCGGCGCTGGCTGCGTTCGGCGCATGGTTGATGGCGAGCCT
CTACACGGTGGCTCCCGAAGAGCAGTCGGTTGAACTGTTTCTGGGCGAATATTCGGCCACGGGTAATTCCGGTCTGAACT
TTGCGCCATGGCCGCTTGTGACGGCCGAGGTTCTGCCGGTCACGCGGGAGCAAACCGAAGATATCGGCTCCCGTACAGGC
AGCGGGCTGATGCTGACCACGGATGAAAACATCATCGACATTGACTTCCAGGTGGTCTGGAACATCAATGATCCGGCTAA
ATTTCTGTTCAACCTTGCAGAACCGCAGGAAACGATTCGCGCGGTGTCTGAATCAGCGATGCGCGAAGTGATTGCGCGCA
ATGAATTGGCACCTATCCTCAACCGGGATCGTCAGGTGATTGCCGATGAGGCCGAACAGCTTATTCAGGCGACACTCGAT
CAATATGACAGCGGCGTGAATATCATCCGTCTCAACCTCGACAAGGCCGACCCGCCGCGCGAGGTCATCGACAGCTTCCG
CGAAGTGCAGGCGGCAGAGCAGGAGCGCGATCGTCTGGAGCGTCAGGCCGATGCCTATGCCAACCGCGTGACCGCGGGCG
CACGGGGTGAAGCCGCCAGCCAGCTGGAACAGGCCGAAGCCTATCGTGCCCAGCAAGTCAACGAGGCACAGGGTGAGGCG
GCGCGTTTCACATCGGTCCTTGAGGAATACGCCAAGGCCCCGGAAGTAACGCGCAAACGTCTCTATCTGGAGACCATGGA
AAAAGTGTTTGGAAGTGTCGACAAGATCATTCTTGAAAGCGGTCTTGGCGGTGAAGGCGGAAACGGGGTCGTGCCCTATC
TGCCACTCAATGAGTTGCGTCGTACAGGCGGAGGGATAAACTGA

Upstream 100 bases:

>100_bases
ATGCGTTCTCCCATGCGCACGGCTTGAATTCCGGGCAGGGCAACGTACCTATGACTTGGTTTGATCGTGACGTTATGCGG
TTTAGAAGGGAAAGAACTTA

Downstream 100 bases:

>100_bases
TGAAAGCTGCTAAGTTTCTGATCCCGATCGGGGTAATTGCGATTGTTGGTGTTCTGAGTTCGGTGTTCATCGTGGATGAA
CGCGAAAAAGCGCTTGTGCT

Product: HflK protein, putative

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 387; Mature: 386

Protein sequence:

>387_residues
MAGNNGGPWGGGGNSGNDRPNGGSGGGNRGSGGGGPRGPGGEGPQIPEIDELVKKGQERLRVLMGGKGGNGTGGGAGGGG
GGGPALTRGTVGLAALAAFGAWLMASLYTVAPEEQSVELFLGEYSATGNSGLNFAPWPLVTAEVLPVTREQTEDIGSRTG
SGLMLTTDENIIDIDFQVVWNINDPAKFLFNLAEPQETIRAVSESAMREVIARNELAPILNRDRQVIADEAEQLIQATLD
QYDSGVNIIRLNLDKADPPREVIDSFREVQAAEQERDRLERQADAYANRVTAGARGEAASQLEQAEAYRAQQVNEAQGEA
ARFTSVLEEYAKAPEVTRKRLYLETMEKVFGSVDKIILESGLGGEGGNGVVPYLPLNELRRTGGGIN

Sequences:

>Translated_387_residues
MAGNNGGPWGGGGNSGNDRPNGGSGGGNRGSGGGGPRGPGGEGPQIPEIDELVKKGQERLRVLMGGKGGNGTGGGAGGGG
GGGPALTRGTVGLAALAAFGAWLMASLYTVAPEEQSVELFLGEYSATGNSGLNFAPWPLVTAEVLPVTREQTEDIGSRTG
SGLMLTTDENIIDIDFQVVWNINDPAKFLFNLAEPQETIRAVSESAMREVIARNELAPILNRDRQVIADEAEQLIQATLD
QYDSGVNIIRLNLDKADPPREVIDSFREVQAAEQERDRLERQADAYANRVTAGARGEAASQLEQAEAYRAQQVNEAQGEA
ARFTSVLEEYAKAPEVTRKRLYLETMEKVFGSVDKIILESGLGGEGGNGVVPYLPLNELRRTGGGIN
>Mature_386_residues
AGNNGGPWGGGGNSGNDRPNGGSGGGNRGSGGGGPRGPGGEGPQIPEIDELVKKGQERLRVLMGGKGGNGTGGGAGGGGG
GGPALTRGTVGLAALAAFGAWLMASLYTVAPEEQSVELFLGEYSATGNSGLNFAPWPLVTAEVLPVTREQTEDIGSRTGS
GLMLTTDENIIDIDFQVVWNINDPAKFLFNLAEPQETIRAVSESAMREVIARNELAPILNRDRQVIADEAEQLIQATLDQ
YDSGVNIIRLNLDKADPPREVIDSFREVQAAEQERDRLERQADAYANRVTAGARGEAASQLEQAEAYRAQQVNEAQGEAA
RFTSVLEEYAKAPEVTRKRLYLETMEKVFGSVDKIILESGLGGEGGNGVVPYLPLNELRRTGGGIN

Specific function: HflC and HflK govern the stability of phage lambda cII protein and have been proposed to encode or regulate a cII- specific protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflK subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790616, Length=377, Percent_Identity=35.0132625994695, Blast_Score=192, Evalue=2e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010201
- InterPro:   IPR020980
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7; PF12221 HflK_N [H]

EC number: NA

Molecular weight: Translated: 40721; Mature: 40589

Theoretical pI: Translated: 4.35; Mature: 4.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAGNNGGPWGGGGNSGNDRPNGGSGGGNRGSGGGGPRGPGGEGPQIPEIDELVKKGQERL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
RVLMGGKGGNGTGGGAGGGGGGGPALTRGTVGLAALAAFGAWLMASLYTVAPEEQSVELF
HHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
LGEYSATGNSGLNFAPWPLVTAEVLPVTREQTEDIGSRTGSGLMLTTDENIIDIDFQVVW
EECCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHCCCCCEEEECCCCEEEEEEEEEE
NINDPAKFLFNLAEPQETIRAVSESAMREVIARNELAPILNRDRQVIADEAEQLIQATLD
ECCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
QYDSGVNIIRLNLDKADPPREVIDSFREVQAAEQERDRLERQADAYANRVTAGARGEAAS
HHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
QLEQAEAYRAQQVNEAQGEAARFTSVLEEYAKAPEVTRKRLYLETMEKVFGSVDKIILES
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHC
GLGGEGGNGVVPYLPLNELRRTGGGIN
CCCCCCCCCCCCCCCHHHHHHHCCCCC
>Mature Secondary Structure 
AGNNGGPWGGGGNSGNDRPNGGSGGGNRGSGGGGPRGPGGEGPQIPEIDELVKKGQERL
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
RVLMGGKGGNGTGGGAGGGGGGGPALTRGTVGLAALAAFGAWLMASLYTVAPEEQSVELF
HHHCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEE
LGEYSATGNSGLNFAPWPLVTAEVLPVTREQTEDIGSRTGSGLMLTTDENIIDIDFQVVW
EECCCCCCCCCCCCCCCCHHHHHHHCCCHHHHHHHHHCCCCCEEEECCCCEEEEEEEEEE
NINDPAKFLFNLAEPQETIRAVSESAMREVIARNELAPILNRDRQVIADEAEQLIQATLD
ECCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
QYDSGVNIIRLNLDKADPPREVIDSFREVQAAEQERDRLERQADAYANRVTAGARGEAAS
HHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHH
QLEQAEAYRAQQVNEAQGEAARFTSVLEEYAKAPEVTRKRLYLETMEKVFGSVDKIILES
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHC
GLGGEGGNGVVPYLPLNELRRTGGGIN
CCCCCCCCCCCCCCCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]