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The map label for this gene is hflC [H]

Identifier: 110679210

GI number: 110679210

Start: 1833865

End: 1834764

Strand: Direct

Name: hflC [H]

Synonym: RD1_1921

Alternate gene names: 110679210

Gene position: 1833865-1834764 (Clockwise)

Preceding gene: 110679209

Following gene: 110679211

Centisome position: 44.37

GC content: 58.33

Gene sequence:

>900_bases
ATGAAAGCTGCTAAGTTTCTGATCCCGATCGGGGTAATTGCGATTGTTGGTGTTCTGAGTTCGGTGTTCATCGTGGATGA
ACGCGAAAAAGCGCTTGTGCTGCAGTTTGGCCAGATCAAATCCGTCAAGGAAGATCCGGGTCTCGCGTTCAAAATTCCGT
TTATTCAGGATGTTGTGCGCTACGATGACAGAACGTTGTCGCTGGATACGGATGTGGTCGAGGTCACGCCATCGGATGAC
CGGCGTCTGGTTGTTGACGCCTTTGCCCGCTACCGCATCTCTGACGTGGTGCAGTTCCGGCAGGCGGTTGGTGTCGGGGG
CCTGCGCGCCGCCGAGGACCGTCTTGAAGGTATCCTCAACCCGACAATCCGGGCGGTTCTGGGTTCTGACGGGGTGACGT
CCAACACGATCCTCTCTGCGGATCGTGCGGAACTGATGGCGCGGATCACAACGCAGGCGCGTCAACGCGCTTTGCCTCTG
GGTCTTGAGGTGATCGACGTGCGTTTGAAACAGACGAACCTGCCCGATCAGAACCTTGACGCGACCTTTGCAAGGATGCG
CGCGGAACGTGAGCGCGAAGCGGCGGACGAAATTGCGCGTGGTGAGGAAGCGGCACAAAGGGTGCGGGCTCTGGCAGATC
GTACGGTGGTCGAACTGACGTCGGAAGCGACGCGCGAGGCCGACATCGTGCGCGGTCAGGCGGATGCGGAGCGGAACGCG
ATTTTCGCAGATGCCTTTGGCGCAGATCCTGAATTCTTTGAATTCTATCGCTCCCTTACTGCCTATGAACGCGCCTTGCA
GGGAACCAACTCGACGATGGTGATGTCACCGGATTCGGAGTTCTTCAACTACCTGCGCAGCGACCAGGGATTGCGTTCTG
AGGAGGGCGAGAGCCGGTGA

Upstream 100 bases:

>100_bases
AGATCATTCTTGAAAGCGGTCTTGGCGGTGAAGGCGGAAACGGGGTCGTGCCCTATCTGCCACTCAATGAGTTGCGTCGT
ACAGGCGGAGGGATAAACTG

Downstream 100 bases:

>100_bases
GCACGATCCTTCTGGCCTTAGGGTTGGTGATGATTATCGAGGGGCTGGCCTATGCGCTGGCCCCTTCGCTTATTGAGCGC
ATGCTTGAGATGTTGCGCTC

Product: HflC protein, putative

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MKAAKFLIPIGVIAIVGVLSSVFIVDEREKALVLQFGQIKSVKEDPGLAFKIPFIQDVVRYDDRTLSLDTDVVEVTPSDD
RRLVVDAFARYRISDVVQFRQAVGVGGLRAAEDRLEGILNPTIRAVLGSDGVTSNTILSADRAELMARITTQARQRALPL
GLEVIDVRLKQTNLPDQNLDATFARMRAEREREAADEIARGEEAAQRVRALADRTVVELTSEATREADIVRGQADAERNA
IFADAFGADPEFFEFYRSLTAYERALQGTNSTMVMSPDSEFFNYLRSDQGLRSEEGESR

Sequences:

>Translated_299_residues
MKAAKFLIPIGVIAIVGVLSSVFIVDEREKALVLQFGQIKSVKEDPGLAFKIPFIQDVVRYDDRTLSLDTDVVEVTPSDD
RRLVVDAFARYRISDVVQFRQAVGVGGLRAAEDRLEGILNPTIRAVLGSDGVTSNTILSADRAELMARITTQARQRALPL
GLEVIDVRLKQTNLPDQNLDATFARMRAEREREAADEIARGEEAAQRVRALADRTVVELTSEATREADIVRGQADAERNA
IFADAFGADPEFFEFYRSLTAYERALQGTNSTMVMSPDSEFFNYLRSDQGLRSEEGESR
>Mature_299_residues
MKAAKFLIPIGVIAIVGVLSSVFIVDEREKALVLQFGQIKSVKEDPGLAFKIPFIQDVVRYDDRTLSLDTDVVEVTPSDD
RRLVVDAFARYRISDVVQFRQAVGVGGLRAAEDRLEGILNPTIRAVLGSDGVTSNTILSADRAELMARITTQARQRALPL
GLEVIDVRLKQTNLPDQNLDATFARMRAEREREAADEIARGEEAAQRVRALADRTVVELTSEATREADIVRGQADAERNA
IFADAFGADPEFFEFYRSLTAYERALQGTNSTMVMSPDSEFFNYLRSDQGLRSEEGESR

Specific function: HflC and HflK govern the stability of phage lambda cII protein and have been proposed to encode or regulate a cII- specific protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790617, Length=310, Percent_Identity=34.5161290322581, Blast_Score=177, Evalue=5e-46,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010200
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: 3.4.-.-

Molecular weight: Translated: 33206; Mature: 33206

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKAAKFLIPIGVIAIVGVLSSVFIVDEREKALVLQFGQIKSVKEDPGLAFKIPFIQDVVR
CCCCHHHHHHHHHHHHHHHHHHHEECCCCCEEEEEHHHHCCCCCCCCCEEECHHHHHHHH
YDDRTLSLDTDVVEVTPSDDRRLVVDAFARYRISDVVQFRQAVGVGGLRAAEDRLEGILN
HCCCEEEECCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHC
PTIRAVLGSDGVTSNTILSADRAELMARITTQARQRALPLGLEVIDVRLKQTNLPDQNLD
HHHHHHHCCCCCCCCCEECHHHHHHHHHHHHHHHHHCCCCCHHHEEEEHHHCCCCCCCCH
ATFARMRAEREREAADEIARGEEAAQRVRALADRTVVELTSEATREADIVRGQADAERNA
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCE
IFADAFGADPEFFEFYRSLTAYERALQGTNSTMVMSPDSEFFNYLRSDQGLRSEEGESR
EEEECCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MKAAKFLIPIGVIAIVGVLSSVFIVDEREKALVLQFGQIKSVKEDPGLAFKIPFIQDVVR
CCCCHHHHHHHHHHHHHHHHHHHEECCCCCEEEEEHHHHCCCCCCCCCEEECHHHHHHHH
YDDRTLSLDTDVVEVTPSDDRRLVVDAFARYRISDVVQFRQAVGVGGLRAAEDRLEGILN
HCCCEEEECCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHC
PTIRAVLGSDGVTSNTILSADRAELMARITTQARQRALPLGLEVIDVRLKQTNLPDQNLD
HHHHHHHCCCCCCCCCEECHHHHHHHHHHHHHHHHHCCCCCHHHEEEEHHHCCCCCCCCH
ATFARMRAEREREAADEIARGEEAAQRVRALADRTVVELTSEATREADIVRGQADAERNA
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCE
IFADAFGADPEFFEFYRSLTAYERALQGTNSTMVMSPDSEFFNYLRSDQGLRSEEGESR
EEEECCCCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]