Click here to switch to the map view.

The map label for this gene is ttcA [H]

Identifier: 110678773

GI number: 110678773

Start: 1385094

End: 1386023

Strand: Reverse

Name: ttcA [H]

Synonym: RD1_1457

Alternate gene names: 110678773

Gene position: 1386023-1385094 (Counterclockwise)

Preceding gene: 110678774

Following gene: 110678772

Centisome position: 33.53

GC content: 56.45

Gene sequence:

>930_bases
GTGGCGCGCACGCTCGCCTTTATGCAGAATGCAGGGGTATCGAGCCTCTTTTGGTTCATCCCCACACGCGATATAGAACG
TCAAGCCAACTTCAGGACGCCGCTGATGCTTGATCATTCAGATGAGATTCACCCGCTCTTTCACGGGGCTCCCAAAACGA
CCGAGTTTCGCAAGCTGCGCAAGCGCCTTGTCAGGCAGACCCGCGACGCGATTGAACGCTATGGCATGATCGAAAAAGAT
GCGCGTTGGCTGGTCTGTTTGTCGGGCGGCAAAGACAGCTACACCCTGCTCGCGGTGCTTTACGAGTTGAAATGGCGCGG
CCTGCTGCCGGTTGAACTGCTGGCGTGCAATCTGGATCAGGGCCAACCCGGTTTTCCCGCCACCGTATTGCCCGAATTTC
TGAAAAAGATGGAGGTGCCACACCGCGTTGAATATCAGGACACCTACTCCATCGTCATGGATAAGGTGCCGCAGGGGCGG
ACGCTTTGCGCGCTGTGTTCTCGGCTGCGGCGCGGCCATCTGTACCGCATCGCGCGCGAAGAGGGTTGTTCGGCCGTCGT
GCTGGGGCACCACCGCGACGATATACTGGAAACGTTTTTCATGAACCTTTTTCACGGCGGTCGGTTGGCAACGATGCCGC
CAAAACTGGTAAACGAAGAAGGCGATTTATTCGTTTATCGACCACTTGCCCATGTCAGCGAAGCCGATTGTGATCGGTTC
TCGACGGCGATGGGCTATCCGATCATCCCTTGCGACCTATGCGGCAGTCAGGATGGATTGCAGCGCCAGCAGGTCAAGGC
CATCCTTGAAGGCTGGGAAAAAAACAGCCCCGGACGGCGGCAAGTCATGTTCAAGGCTTTGATGAACACACGCCCCTCGC
ATCTTTTGGACACGGCGCTTTTTGATTTCGCTGGTCTTGCACGAAAATAG

Upstream 100 bases:

>100_bases
CGTGGCTGACCCTGCGGCGGATTTTGCGTTGTCACCCGTGGGGGAAATGCGGCTATGACCCTGTGCCCGAGCGCACGCGC
AAGCCCTGACCCTGCAATCC

Downstream 100 bases:

>100_bases
ATCGGTTTTTAGGCAATACCATCGTAAAAACCATCCGCCTGTTAACCGAGACGTCATTCTGACTCGTCTAGTCTCTACGC
GTTTACCGCTATGCAAAGCG

Product: C32 tRNA thiolase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 309; Mature: 308

Protein sequence:

>309_residues
MARTLAFMQNAGVSSLFWFIPTRDIERQANFRTPLMLDHSDEIHPLFHGAPKTTEFRKLRKRLVRQTRDAIERYGMIEKD
ARWLVCLSGGKDSYTLLAVLYELKWRGLLPVELLACNLDQGQPGFPATVLPEFLKKMEVPHRVEYQDTYSIVMDKVPQGR
TLCALCSRLRRGHLYRIAREEGCSAVVLGHHRDDILETFFMNLFHGGRLATMPPKLVNEEGDLFVYRPLAHVSEADCDRF
STAMGYPIIPCDLCGSQDGLQRQQVKAILEGWEKNSPGRRQVMFKALMNTRPSHLLDTALFDFAGLARK

Sequences:

>Translated_309_residues
MARTLAFMQNAGVSSLFWFIPTRDIERQANFRTPLMLDHSDEIHPLFHGAPKTTEFRKLRKRLVRQTRDAIERYGMIEKD
ARWLVCLSGGKDSYTLLAVLYELKWRGLLPVELLACNLDQGQPGFPATVLPEFLKKMEVPHRVEYQDTYSIVMDKVPQGR
TLCALCSRLRRGHLYRIAREEGCSAVVLGHHRDDILETFFMNLFHGGRLATMPPKLVNEEGDLFVYRPLAHVSEADCDRF
STAMGYPIIPCDLCGSQDGLQRQQVKAILEGWEKNSPGRRQVMFKALMNTRPSHLLDTALFDFAGLARK
>Mature_308_residues
ARTLAFMQNAGVSSLFWFIPTRDIERQANFRTPLMLDHSDEIHPLFHGAPKTTEFRKLRKRLVRQTRDAIERYGMIEKDA
RWLVCLSGGKDSYTLLAVLYELKWRGLLPVELLACNLDQGQPGFPATVLPEFLKKMEVPHRVEYQDTYSIVMDKVPQGRT
LCALCSRLRRGHLYRIAREEGCSAVVLGHHRDDILETFFMNLFHGGRLATMPPKLVNEEGDLFVYRPLAHVSEADCDRFS
TAMGYPIIPCDLCGSQDGLQRQQVKAILEGWEKNSPGRRQVMFKALMNTRPSHLLDTALFDFAGLARK

Specific function: Required for the thiolation of cytidine in position 32 of tRNA, to form 2-thiocytidine (s(2)C32) [H]

COG id: COG0037

COG function: function code D; Predicted ATPase of the PP-loop superfamily implicated in cell cycle control

Gene ontology:

Cell location: Cytoplasm (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the TtcA family [H]

Homologues:

Organism=Escherichia coli, GI1787606, Length=252, Percent_Identity=52.7777777777778, Blast_Score=289, Evalue=2e-79,
Organism=Caenorhabditis elegans, GI193211090, Length=248, Percent_Identity=31.4516129032258, Blast_Score=117, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI17540090, Length=182, Percent_Identity=30.7692307692308, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012089
- InterPro:   IPR014729
- InterPro:   IPR011063 [H]

Pfam domain/function: PF01171 ATP_bind_3 [H]

EC number: NA

Molecular weight: Translated: 35368; Mature: 35236

Theoretical pI: Translated: 8.73; Mature: 8.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.6 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
6.1 %Cys+Met (Translated Protein)
2.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARTLAFMQNAGVSSLFWFIPTRDIERQANFRTPLMLDHSDEIHPLFHGAPKTTEFRKLR
CCHHHHHHHCCCCCCEEEECCCHHHHHHCCCCCCEEECCCCCCCHHHCCCCCCHHHHHHH
KRLVRQTRDAIERYGMIEKDARWLVCLSGGKDSYTLLAVLYELKWRGLLPVELLACNLDQ
HHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCHHHHEECCCC
GQPGFPATVLPEFLKKMEVPHRVEYQDTYSIVMDKVPQGRTLCALCSRLRRGHLYRIARE
CCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEHHHH
EGCSAVVLGHHRDDILETFFMNLFHGGRLATMPPKLVNEEGDLFVYRPLAHVSEADCDRF
CCCCEEEECCCHHHHHHHHHHHHHCCCEEECCCHHHHCCCCCEEEECCHHHCCHHHHHHH
STAMGYPIIPCDLCGSQDGLQRQQVKAILEGWEKNSPGRRQVMFKALMNTRPSHLLDTAL
HHHCCCCCEEHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHH
FDFAGLARK
HHHHHHCCC
>Mature Secondary Structure 
ARTLAFMQNAGVSSLFWFIPTRDIERQANFRTPLMLDHSDEIHPLFHGAPKTTEFRKLR
CHHHHHHHCCCCCCEEEECCCHHHHHHCCCCCCEEECCCCCCCHHHCCCCCCHHHHHHH
KRLVRQTRDAIERYGMIEKDARWLVCLSGGKDSYTLLAVLYELKWRGLLPVELLACNLDQ
HHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCCHHHHEECCCC
GQPGFPATVLPEFLKKMEVPHRVEYQDTYSIVMDKVPQGRTLCALCSRLRRGHLYRIARE
CCCCCCHHHHHHHHHHCCCCCCCCHHHHHHHHHHCCCCCCHHHHHHHHHHCCCEEEHHHH
EGCSAVVLGHHRDDILETFFMNLFHGGRLATMPPKLVNEEGDLFVYRPLAHVSEADCDRF
CCCCEEEECCCHHHHHHHHHHHHHCCCEEECCCHHHHCCCCCEEEECCHHHCCHHHHHHH
STAMGYPIIPCDLCGSQDGLQRQQVKAILEGWEKNSPGRRQVMFKALMNTRPSHLLDTAL
HHHCCCCCEEHHCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCHHHHHHHHH
FDFAGLARK
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA