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The map label for this gene is dnaQ [H]

Identifier: 110678446

GI number: 110678446

Start: 1062596

End: 1063993

Strand: Reverse

Name: dnaQ [H]

Synonym: RD1_1111

Alternate gene names: 110678446

Gene position: 1063993-1062596 (Counterclockwise)

Preceding gene: 110678447

Following gene: 110678443

Centisome position: 25.74

GC content: 59.59

Gene sequence:

>1398_bases
ATGAAAAACCTCAGCCTCCGGCTCCGGGTCTTTCTGTTCTTTTGCCTGACGGCCTTTGGCAGTATCGCGATCTGCCTTGG
CGCGCTTTACATGGGGTTTCGCCAGTTGGGGGACGGTGATGCGCTGTCGGCCTTCATCACGTCCGGTGTGATCGCGGGCT
TTGGCATTCTGGGTCTGGTGGTCCTGATCTGGCTTTTGTTCGACGAAAACGTCAGCAAACCGATCGAGGCATTGGCCGCC
AGTCTGCGCGTGCGCACCCACGTCGATATCGACACGGAAATCGAAGCGGAAACCGCCAAATACCTCGGTGATCTGGCACC
GGCTGTCTGCGCGATCCACCGCAAGCTCAGGGATGAGACGCGCGCCTCCTCCGAGGCGGTGGTGGAACGCACCGCGCGGC
TGGATGCGCAGCGCTCGCAACTGTTGCAAATCCTGTCTGACATTCCCGTCGCCGTGATCGTGGCGCGGCAGGATCACCAG
ATCATCCTTTATGACGGGCAGGCCGCCGACCTGATGGAACGGGAATGCCCTGCCCGCCTCAAAGGATCGGTGTTTGACTA
CCTTGACAAACAATCCGTGCTTGAGGCCCTGTCTGCGCTGAAAAAGCAAAACGCCCTGCGCCATGAGATCGCCCTCAAAG
GCCGCTCCGGCGCGGTTTACAAAGGTCACATCCGGGTGTTCGGCGCGGATGCGGGCTACACCTTGATGCTGGAGCCACTG
CGCCCCGATGCCGCGCGCCCTCTGGTCTATGACTTTGACCTGCTCGACTTCGAAGAACCCACATCGCTGGATCAAACGAG
ACTGCGTGATCTGACATTCGTTGTTTTTGACAGCGAAACGACCGGTCTTGATCCACATACGGACGAGGTTGTGCAATTGG
GCGCCGTGCGTGTCGTCAACGGCAAGATCATCGAAGGCGAGGTCTTTGATACGCTGGTCAATCCCGGCCGGACCATCCCG
CCGGGGTCCACGGCGGTGCATCAGATCAGTGATGCCATGGTCGCCGATGCGCCGGGCTTTGATGTCGCCTGCCGCGCGTT
CCATCAATTCGCCGAACACGCCGTGATCGTCGCCCATAACGCCCCCTTTGATATGGCATTCCTCAGACGCCAGTGTCGTG
ATCAGGACTATGCGTTCGACAACCCCATTCTGGATACGGTACATCTGTCCGCGGTGGTTTTTGGCGGCTCGGCAGAACAT
ACGCTGGATGCTTTATGCGACCGTCTGAACGTGCATATTCCCGATGACGTGCGCCACACCGGGCTTGGCGATGCGCTGGC
CACGGCCAAGGCGCTGGTTGCGCTGATCCCGGTGCTGGAGGCGCGGGGTTTTACAACCTTTGAACAGGTCCGCGCGGAAA
TTCAGAAACACAGCCGCATTCTGAAGGTTGAAGCCTAG

Upstream 100 bases:

>100_bases
GGCGTGGAATTTGGCGACAACGGTGAAGCACTGGGCGTTGACTGGATCGCCGTCAGTGCCAGCGATCCAATCCTGAGGGT
CGCCTGCGAGGAGGTGTGAG

Downstream 100 bases:

>100_bases
CGGGATTCCCGCCTGCGCCAGAGCCAGCCGTGCAGGGCAAGGTAGGGCAGATAGAACGCAAAGACCTGAATGACATCGAA
CGGCCCGGAAAAGTCATCCC

Product: exonuclease, putative

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 465; Mature: 465

Protein sequence:

>465_residues
MKNLSLRLRVFLFFCLTAFGSIAICLGALYMGFRQLGDGDALSAFITSGVIAGFGILGLVVLIWLLFDENVSKPIEALAA
SLRVRTHVDIDTEIEAETAKYLGDLAPAVCAIHRKLRDETRASSEAVVERTARLDAQRSQLLQILSDIPVAVIVARQDHQ
IILYDGQAADLMERECPARLKGSVFDYLDKQSVLEALSALKKQNALRHEIALKGRSGAVYKGHIRVFGADAGYTLMLEPL
RPDAARPLVYDFDLLDFEEPTSLDQTRLRDLTFVVFDSETTGLDPHTDEVVQLGAVRVVNGKIIEGEVFDTLVNPGRTIP
PGSTAVHQISDAMVADAPGFDVACRAFHQFAEHAVIVAHNAPFDMAFLRRQCRDQDYAFDNPILDTVHLSAVVFGGSAEH
TLDALCDRLNVHIPDDVRHTGLGDALATAKALVALIPVLEARGFTTFEQVRAEIQKHSRILKVEA

Sequences:

>Translated_465_residues
MKNLSLRLRVFLFFCLTAFGSIAICLGALYMGFRQLGDGDALSAFITSGVIAGFGILGLVVLIWLLFDENVSKPIEALAA
SLRVRTHVDIDTEIEAETAKYLGDLAPAVCAIHRKLRDETRASSEAVVERTARLDAQRSQLLQILSDIPVAVIVARQDHQ
IILYDGQAADLMERECPARLKGSVFDYLDKQSVLEALSALKKQNALRHEIALKGRSGAVYKGHIRVFGADAGYTLMLEPL
RPDAARPLVYDFDLLDFEEPTSLDQTRLRDLTFVVFDSETTGLDPHTDEVVQLGAVRVVNGKIIEGEVFDTLVNPGRTIP
PGSTAVHQISDAMVADAPGFDVACRAFHQFAEHAVIVAHNAPFDMAFLRRQCRDQDYAFDNPILDTVHLSAVVFGGSAEH
TLDALCDRLNVHIPDDVRHTGLGDALATAKALVALIPVLEARGFTTFEQVRAEIQKHSRILKVEA
>Mature_465_residues
MKNLSLRLRVFLFFCLTAFGSIAICLGALYMGFRQLGDGDALSAFITSGVIAGFGILGLVVLIWLLFDENVSKPIEALAA
SLRVRTHVDIDTEIEAETAKYLGDLAPAVCAIHRKLRDETRASSEAVVERTARLDAQRSQLLQILSDIPVAVIVARQDHQ
IILYDGQAADLMERECPARLKGSVFDYLDKQSVLEALSALKKQNALRHEIALKGRSGAVYKGHIRVFGADAGYTLMLEPL
RPDAARPLVYDFDLLDFEEPTSLDQTRLRDLTFVVFDSETTGLDPHTDEVVQLGAVRVVNGKIIEGEVFDTLVNPGRTIP
PGSTAVHQISDAMVADAPGFDVACRAFHQFAEHAVIVAHNAPFDMAFLRRQCRDQDYAFDNPILDTVHLSAVVFGGSAEH
TLDALCDRLNVHIPDDVRHTGLGDALATAKALVALIPVLEARGFTTFEQVRAEIQKHSRILKVEA

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease [H]

COG id: COG2176

COG function: function code L; DNA polymerase III, alpha subunit (gram-positive type)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786409, Length=205, Percent_Identity=29.2682926829268, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006054
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR000014
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 50990; Mature: 50990

Theoretical pI: Translated: 5.31; Mature: 5.31

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNLSLRLRVFLFFCLTAFGSIAICLGALYMGFRQLGDGDALSAFITSGVIAGFGILGLV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
VLIWLLFDENVSKPIEALAASLRVRTHVDIDTEIEAETAKYLGDLAPAVCAIHRKLRDET
HHHHHHHCCCCCHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RASSEAVVERTARLDAQRSQLLQILSDIPVAVIVARQDHQIILYDGQAADLMERECPARL
HCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCEEEEECCCHHHHHHHCCCHHH
KGSVFDYLDKQSVLEALSALKKQNALRHEIALKGRSGAVYKGHIRVFGADAGYTLMLEPL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEEEEEEECCCCCEEEEECC
RPDAARPLVYDFDLLDFEEPTSLDQTRLRDLTFVVFDSETTGLDPHTDEVVQLGAVRVVN
CCCCCCCEEEEECCCCCCCCCCCHHHHHCEEEEEEECCCCCCCCCCHHHHHHHCCEEEEC
GKIIEGEVFDTLVNPGRTIPPGSTAVHQISDAMVADAPGFDVACRAFHQFAEHAVIVAHN
CEEECCHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCEEEEEEC
APFDMAFLRRQCRDQDYAFDNPILDTVHLSAVVFGGSAEHTLDALCDRLNVHIPDDVRHT
CCCHHHHHHHHHCCCCCCCCCCCHHHHEEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCC
GLGDALATAKALVALIPVLEARGFTTFEQVRAEIQKHSRILKVEA
CCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEECC
>Mature Secondary Structure
MKNLSLRLRVFLFFCLTAFGSIAICLGALYMGFRQLGDGDALSAFITSGVIAGFGILGLV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHH
VLIWLLFDENVSKPIEALAASLRVRTHVDIDTEIEAETAKYLGDLAPAVCAIHRKLRDET
HHHHHHHCCCCCHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
RASSEAVVERTARLDAQRSQLLQILSDIPVAVIVARQDHQIILYDGQAADLMERECPARL
HCHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEECCCEEEEECCCHHHHHHHCCCHHH
KGSVFDYLDKQSVLEALSALKKQNALRHEIALKGRSGAVYKGHIRVFGADAGYTLMLEPL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCEEEEEEEEEECCCCCEEEEECC
RPDAARPLVYDFDLLDFEEPTSLDQTRLRDLTFVVFDSETTGLDPHTDEVVQLGAVRVVN
CCCCCCCEEEEECCCCCCCCCCCHHHHHCEEEEEEECCCCCCCCCCHHHHHHHCCEEEEC
GKIIEGEVFDTLVNPGRTIPPGSTAVHQISDAMVADAPGFDVACRAFHQFAEHAVIVAHN
CEEECCHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCEEEEEEC
APFDMAFLRRQCRDQDYAFDNPILDTVHLSAVVFGGSAEHTLDALCDRLNVHIPDDVRHT
CCCHHHHHHHHHCCCCCCCCCCCHHHHEEEEEEECCCCHHHHHHHHHHCCCCCCCCCCCC
GLGDALATAKALVALIPVLEARGFTTFEQVRAEIQKHSRILKVEA
CCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9256491 [H]