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The map label for this gene is yhdI [H]

Identifier: 110678324

GI number: 110678324

Start: 943316

End: 944797

Strand: Reverse

Name: yhdI [H]

Synonym: RD1_0978

Alternate gene names: 110678324

Gene position: 944797-943316 (Counterclockwise)

Preceding gene: 110678327

Following gene: 110678323

Centisome position: 22.86

GC content: 63.29

Gene sequence:

>1482_bases
ATGGCGCTTCCCGTCGAAACGTTCTTTCTGCACCCTGACGCACAGGGCACGCTGCAATCGCAGATCCAGCAGATGATCGC
GCAGGGAATCCTGTCCGGGCGGTTCCAGAGGGCTGAAAAACTGCCCTCAACGCGCAGGCTGGCCGCGCATCTGGGCGTCA
GCCGGATTACCGTGACAATCGCCTATACCGAACTTCTGGCCAATGATTACCTGGTCTCGCGCGGTCGCTCGGGCTACTAC
GTCTCGGACAACGCGCCGGTCCCGCCCGCCTTTGCCCCCGGGCCCACCAGAACCGATGCGGTGGACTGGACCCGCGCAAT
CGGCCAGCGGTTTTCCGGCGGGGACACCGTGCGCAAGCCCCCGGACTGGGAATCCTATCGCTTCCCCTTCATCTACGGGC
AGGCGGATCCCGCGCTCTTTGATCATGCAAACTGGCGGCTATGCGCCCTCAAGGCGCTGGGGCAAAAGGATTTCACCGCC
CTGACCACCGATTACTATGACCAGGACGATCCGCAGCTGATCGAATTCATCGCCCGCCACACCCTGCCCCGGCGCGGGAT
TGCCGCCCGCCCCGAACAGGTGCTGATCACGCTTGGCGCGCAGAACGCGCTCTGGCTCACCACGCAGGTGTTGCTGACAC
AGCGGCGGCGCGCCGCCCTGGAAGACCCTTGTTATCATGCCCTTAGGGATATCCTGTCACAGTCGCGCTGCCATGTGACT
CCTGTGCGCCTTGATGCCGACGGCTTGCCCCCCGATGCCATTCCGCCGGATGCGGATGTGATCTTCACAACCCCCAGCCA
CCAGTGTCCGACCACCGGCACGATGCCCATGGCGCGCCGCCATGACCTGCTGAAACGCGCCGCAGAGATGGATGCGATCA
TCGTCGAGGATGACTACGAATTCGAAATGTCCTTCCTGAAAAGCCCCTCGCCCGCGCTCAAGAGCCTGGATGCAGACGGG
CGCGTCATCTATGTCGGCAGCTTTTCGAAATCCCTGTTTCCCGGCCTGCGTCTGGGATATCTCGTTGGCTCCGAACCCTT
TATCCGCGAAGCGCGCGCGCTCAGGGCTTCCGTGCTGCGCCACCCGCCCGGCCATATACAGCGCACCGCCGCCTATTTCC
TGTCGCTCGGCCATCATGATGCGCTGATCCGGCGCATGGGCGCCACGCTGCACGAACGCCGGCAGGTGATGAGCGACGCG
ATCGCACAGAACAGGCTTCAGATCGCAGGGCAAGGCGCGCATGGCGGCTCCTCTTTCTGGATGCGCGCGCCCGAAAACAT
CGACACGCAGGACCTTGCCCGCAGGCTGCGCGCCCGCGATGTGCTGATCGAACCGGGGCATTCGTTTTTCGCCGGGGCGG
CGCAGCCCCGAAACTTTTACCGGCTGGCCTATTCGTCCATTCCCGCAAGCCGAATACTGCAGGGCGTCAGCCGGGTTGCC
GAAGAAATCAACACCTTGTCAAATCTGGCATTAAATGGCTGA

Upstream 100 bases:

>100_bases
CGCGGCGCGGCGGCCTTAGACACCTGTTCCGACATCGGGGATTTTGGACCTGCTATAATACCAGATTGCATCGCTTATAA
GTCCAGTGTAGGCTATCCCC

Downstream 100 bases:

>100_bases
TCAATCTGGCCCTAACACAATGTAAGCGCATACATTAGATAACAAGCAACCCTAGATTCGCGCATGGATTTCACCCCCGG
AGGAACACCCGCCATGAAAA

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 493; Mature: 492

Protein sequence:

>493_residues
MALPVETFFLHPDAQGTLQSQIQQMIAQGILSGRFQRAEKLPSTRRLAAHLGVSRITVTIAYTELLANDYLVSRGRSGYY
VSDNAPVPPAFAPGPTRTDAVDWTRAIGQRFSGGDTVRKPPDWESYRFPFIYGQADPALFDHANWRLCALKALGQKDFTA
LTTDYYDQDDPQLIEFIARHTLPRRGIAARPEQVLITLGAQNALWLTTQVLLTQRRRAALEDPCYHALRDILSQSRCHVT
PVRLDADGLPPDAIPPDADVIFTTPSHQCPTTGTMPMARRHDLLKRAAEMDAIIVEDDYEFEMSFLKSPSPALKSLDADG
RVIYVGSFSKSLFPGLRLGYLVGSEPFIREARALRASVLRHPPGHIQRTAAYFLSLGHHDALIRRMGATLHERRQVMSDA
IAQNRLQIAGQGAHGGSSFWMRAPENIDTQDLARRLRARDVLIEPGHSFFAGAAQPRNFYRLAYSSIPASRILQGVSRVA
EEINTLSNLALNG

Sequences:

>Translated_493_residues
MALPVETFFLHPDAQGTLQSQIQQMIAQGILSGRFQRAEKLPSTRRLAAHLGVSRITVTIAYTELLANDYLVSRGRSGYY
VSDNAPVPPAFAPGPTRTDAVDWTRAIGQRFSGGDTVRKPPDWESYRFPFIYGQADPALFDHANWRLCALKALGQKDFTA
LTTDYYDQDDPQLIEFIARHTLPRRGIAARPEQVLITLGAQNALWLTTQVLLTQRRRAALEDPCYHALRDILSQSRCHVT
PVRLDADGLPPDAIPPDADVIFTTPSHQCPTTGTMPMARRHDLLKRAAEMDAIIVEDDYEFEMSFLKSPSPALKSLDADG
RVIYVGSFSKSLFPGLRLGYLVGSEPFIREARALRASVLRHPPGHIQRTAAYFLSLGHHDALIRRMGATLHERRQVMSDA
IAQNRLQIAGQGAHGGSSFWMRAPENIDTQDLARRLRARDVLIEPGHSFFAGAAQPRNFYRLAYSSIPASRILQGVSRVA
EEINTLSNLALNG
>Mature_492_residues
ALPVETFFLHPDAQGTLQSQIQQMIAQGILSGRFQRAEKLPSTRRLAAHLGVSRITVTIAYTELLANDYLVSRGRSGYYV
SDNAPVPPAFAPGPTRTDAVDWTRAIGQRFSGGDTVRKPPDWESYRFPFIYGQADPALFDHANWRLCALKALGQKDFTAL
TTDYYDQDDPQLIEFIARHTLPRRGIAARPEQVLITLGAQNALWLTTQVLLTQRRRAALEDPCYHALRDILSQSRCHVTP
VRLDADGLPPDAIPPDADVIFTTPSHQCPTTGTMPMARRHDLLKRAAEMDAIIVEDDYEFEMSFLKSPSPALKSLDADGR
VIYVGSFSKSLFPGLRLGYLVGSEPFIREARALRASVLRHPPGHIQRTAAYFLSLGHHDALIRRMGATLHERRQVMSDAI
AQNRLQIAGQGAHGGSSFWMRAPENIDTQDLARRLRARDVLIEPGHSFFAGAAQPRNFYRLAYSSIPASRILQGVSRVAE
EINTLSNLALNG

Specific function: Unknown

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=295, Percent_Identity=24.406779661017, Blast_Score=96, Evalue=1e-19,
Organism=Homo sapiens, GI33469970, Length=295, Percent_Identity=24.406779661017, Blast_Score=96, Evalue=1e-19,
Organism=Escherichia coli, GI1787710, Length=479, Percent_Identity=27.348643006263, Blast_Score=124, Evalue=1e-29,
Organism=Escherichia coli, GI1790797, Length=458, Percent_Identity=27.9475982532751, Blast_Score=122, Evalue=4e-29,
Organism=Saccharomyces cerevisiae, GI6321236, Length=385, Percent_Identity=25.1948051948052, Blast_Score=92, Evalue=3e-19,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 54814; Mature: 54683

Theoretical pI: Translated: 9.01; Mature: 9.01

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALPVETFFLHPDAQGTLQSQIQQMIAQGILSGRFQRAEKLPSTRRLAAHLGVSRITVTI
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHEEEEE
AYTELLANDYLVSRGRSGYYVSDNAPVPPAFAPGPTRTDAVDWTRAIGQRFSGGDTVRKP
EHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCC
PDWESYRFPFIYGQADPALFDHANWRLCALKALGQKDFTALTTDYYDQDDPQLIEFIARH
CCCCCCCCCEEECCCCCCHHCCCCCEEEEHHHCCCCCCEEEECCCCCCCCHHHHHHHHHH
TLPRRGIAARPEQVLITLGAQNALWLTTQVLLTQRRRAALEDPCYHALRDILSQSRCHVT
CCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEE
PVRLDADGLPPDAIPPDADVIFTTPSHQCPTTGTMPMARRHDLLKRAAEMDAIIVEDDYE
EEEECCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEECCCH
FEMSFLKSPSPALKSLDADGRVIYVGSFSKSLFPGLRLGYLVGSEPFIREARALRASVLR
HHHHHHCCCCHHHHHCCCCCCEEEEECCCHHHCCCHHHHHHCCCCHHHHHHHHHHHHHHH
HPPGHIQRTAAYFLSLGHHDALIRRMGATLHERRQVMSDAIAQNRLQIAGQGAHGGSSFW
CCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCE
MRAPENIDTQDLARRLRARDVLIEPGHSFFAGAAQPRNFYRLAYSSIPASRILQGVSRVA
EECCCCCCHHHHHHHHHHCCEEECCCCCHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHH
EEINTLSNLALNG
HHHHHHHHHCCCC
>Mature Secondary Structure 
ALPVETFFLHPDAQGTLQSQIQQMIAQGILSGRFQRAEKLPSTRRLAAHLGVSRITVTI
CCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCHHHEEEEE
AYTELLANDYLVSRGRSGYYVSDNAPVPPAFAPGPTRTDAVDWTRAIGQRFSGGDTVRKP
EHHHHHHHHHHHHCCCCCEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCC
PDWESYRFPFIYGQADPALFDHANWRLCALKALGQKDFTALTTDYYDQDDPQLIEFIARH
CCCCCCCCCEEECCCCCCHHCCCCCEEEEHHHCCCCCCEEEECCCCCCCCHHHHHHHHHH
TLPRRGIAARPEQVLITLGAQNALWLTTQVLLTQRRRAALEDPCYHALRDILSQSRCHVT
CCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCEEE
PVRLDADGLPPDAIPPDADVIFTTPSHQCPTTGTMPMARRHDLLKRAAEMDAIIVEDDYE
EEEECCCCCCCCCCCCCCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHCCEEEEECCCH
FEMSFLKSPSPALKSLDADGRVIYVGSFSKSLFPGLRLGYLVGSEPFIREARALRASVLR
HHHHHHCCCCHHHHHCCCCCCEEEEECCCHHHCCCHHHHHHCCCCHHHHHHHHHHHHHHH
HPPGHIQRTAAYFLSLGHHDALIRRMGATLHERRQVMSDAIAQNRLQIAGQGAHGGSSFW
CCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCE
MRAPENIDTQDLARRLRARDVLIEPGHSFFAGAAQPRNFYRLAYSSIPASRILQGVSRVA
EECCCCCCHHHHHHHHHHCCEEECCCCCHHCCCCCCCHHHHHHHHCCCHHHHHHHHHHHH
EEINTLSNLALNG
HHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9579061; 9384377 [H]