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The map label for this gene is coaE [H]

Identifier: 110677833

GI number: 110677833

Start: 428871

End: 429464

Strand: Direct

Name: coaE [H]

Synonym: RD1_0439

Alternate gene names: 110677833

Gene position: 428871-429464 (Clockwise)

Preceding gene: 110677832

Following gene: 110677834

Centisome position: 10.38

GC content: 55.72

Gene sequence:

>594_bases
GTGACGTTCAAACTCGGTCTCACAGGCTCCATCGGCATGGGTAAATCCACCACGGCACAGCTTTTTGTGGAACTTGGCTG
CGCGCTTTGGGATGCGGATGCGGCTGTTCATCGGCTTTATGTCGAGGGCGGTGCAGCGGTTGCGCCCATCGGGGCGATTT
ATCCCACCGTGATTCATAAAAACAGCGTCTCACGGGATGCTCTGCGCGACTTGATTCAGAATGATCCCTCGGTCTTGCGC
CGGATAGAAAAGATCGTACATCCGCTGGTCGGCGCGGACAGAACCGAGTTTCTGGACCAAACAAAAAGCGACATCACCGT
GCTGGATATCCCGCTCCTGTTTGAAACCGGGGCGGACAGCGACATGGACGCCGTGGCCTGTGTCCGCACAACTGCAGAGG
AACAGGAGAGACGCGTTCTGGCGCGCGGCAAGATGACAGCAAAGCAATTTCAACAGATCAGGCACAAACAGATGCCGAAT
GCGGAAAAATGTGCGCGGGCTGATTTCGTGATCGAAACGGATACGCTTGAACATGCACGTGCGCAGGTTCAGACTATTAC
GGAGCAGATACGGAGGGCGATTGCAGATGCGTGA

Upstream 100 bases:

>100_bases
ACGGGCTGGGGATGCTGTTACATCAAGGCGTTCCGGGATTTGAGCGCTGGTTTGGTCGGCGACCGGATGTCACAGATGCC
ACGCGCGCAGCGGTGCTCGG

Downstream 100 bases:

>100_bases
AATTGTGTTGGACACGGAAACGACTGGTTTCGACCCTGAATCAGGCGACCGGATTGTCGAGATTGGCGCGGTGGAATTGA
TGGGCCATGTTGCGACGGGC

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 197; Mature: 196

Protein sequence:

>197_residues
MTFKLGLTGSIGMGKSTTAQLFVELGCALWDADAAVHRLYVEGGAAVAPIGAIYPTVIHKNSVSRDALRDLIQNDPSVLR
RIEKIVHPLVGADRTEFLDQTKSDITVLDIPLLFETGADSDMDAVACVRTTAEEQERRVLARGKMTAKQFQQIRHKQMPN
AEKCARADFVIETDTLEHARAQVQTITEQIRRAIADA

Sequences:

>Translated_197_residues
MTFKLGLTGSIGMGKSTTAQLFVELGCALWDADAAVHRLYVEGGAAVAPIGAIYPTVIHKNSVSRDALRDLIQNDPSVLR
RIEKIVHPLVGADRTEFLDQTKSDITVLDIPLLFETGADSDMDAVACVRTTAEEQERRVLARGKMTAKQFQQIRHKQMPN
AEKCARADFVIETDTLEHARAQVQTITEQIRRAIADA
>Mature_196_residues
TFKLGLTGSIGMGKSTTAQLFVELGCALWDADAAVHRLYVEGGAAVAPIGAIYPTVIHKNSVSRDALRDLIQNDPSVLRR
IEKIVHPLVGADRTEFLDQTKSDITVLDIPLLFETGADSDMDAVACVRTTAEEQERRVLARGKMTAKQFQQIRHKQMPNA
EKCARADFVIETDTLEHARAQVQTITEQIRRAIADA

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=180, Percent_Identity=30, Blast_Score=71, Evalue=5e-13,
Organism=Homo sapiens, GI191252795, Length=180, Percent_Identity=30, Blast_Score=71, Evalue=5e-13,
Organism=Escherichia coli, GI1786292, Length=176, Percent_Identity=28.4090909090909, Blast_Score=69, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17554944, Length=200, Percent_Identity=28, Blast_Score=73, Evalue=9e-14,
Organism=Drosophila melanogaster, GI24644728, Length=198, Percent_Identity=28.2828282828283, Blast_Score=80, Evalue=6e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 21685; Mature: 21554

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTFKLGLTGSIGMGKSTTAQLFVELGCALWDADAAVHRLYVEGGAAVAPIGAIYPTVIHK
CEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCC
NSVSRDALRDLIQNDPSVLRRIEKIVHPLVGADRTEFLDQTKSDITVLDIPLLFETGADS
CCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCEEEEEEEEEEECCCCC
DMDAVACVRTTAEEQERRVLARGKMTAKQFQQIRHKQMPNAEKCARADFVIETDTLEHAR
CHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHCCEEEECCHHHHHH
AQVQTITEQIRRAIADA
HHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TFKLGLTGSIGMGKSTTAQLFVELGCALWDADAAVHRLYVEGGAAVAPIGAIYPTVIHK
EEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCC
NSVSRDALRDLIQNDPSVLRRIEKIVHPLVGADRTEFLDQTKSDITVLDIPLLFETGADS
CCCCHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHCCCCEEEEEEEEEEECCCCC
DMDAVACVRTTAEEQERRVLARGKMTAKQFQQIRHKQMPNAEKCARADFVIETDTLEHAR
CHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCHHHHHHCCEEEECCHHHHHH
AQVQTITEQIRRAIADA
HHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA