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The map label for this gene is dnaQ [H]

Identifier: 110677834

GI number: 110677834

Start: 429457

End: 430143

Strand: Direct

Name: dnaQ [H]

Synonym: RD1_0440

Alternate gene names: 110677834

Gene position: 429457-430143 (Clockwise)

Preceding gene: 110677833

Following gene: 110677837

Centisome position: 10.39

GC content: 53.57

Gene sequence:

>687_bases
ATGCGTGAAATTGTGTTGGACACGGAAACGACTGGTTTCGACCCTGAATCAGGCGACCGGATTGTCGAGATTGGCGCGGT
GGAATTGATGGGCCATGTTGCGACGGGCAGAACCTATCACCAGTATATCAACCCCGAACGATCCATGCCGGAGGAAGCGT
TTCAGGTGCACGGGCTGGGCGATGATTTTCTGCGCGACAAACCCAAATTTGCCGAGGTCGGACAGGCCTTTCTTGATTTT
ATCGGGGATGCCAAACTTGTTATCCATAATGCGGCTTTTGATATCAAGTTTCTCAATGCTGAATTGGGTTGGATAAACCT
GCCGAAAATACCCTGGGAACAGGCGATTGATACGCTGGATATCGCGCGTAAACGTTTTCCGGGCTCGCCTGCCTCGCTGG
ACGCTTTATGCCGCCGCTTTGGCATTGATAATACGTCGCGGACGCTGCACGGTGCTTTGCTCGACAGTGAAATTCTGGCT
GAGGTCTATCTTGAACTTATCGGGGGGCGACAGCCTGATTTCGGCCTGTCCAACATTCCGCAAAAATCCGCAGGTGATAC
ATCTGTGGACTGGACGCCCCGACCGCGTCCCACGCCGCTACCTTCGCGAATAACCGAGGAAGAAGCCGCCGCCCATGCAG
ACTTTGTTGCGAAATTGGGCGACGACGCTGTTTGGTTGAAAACCTGA

Upstream 100 bases:

>100_bases
AAATGTGCGCGGGCTGATTTCGTGATCGAAACGGATACGCTTGAACATGCACGTGCGCAGGTTCAGACTATTACGGAGCA
GATACGGAGGGCGATTGCAG

Downstream 100 bases:

>100_bases
GATCAGGCGTCCATCTTGGGCGCTTCGCTTGATTGGCGGCGCGCCAGCTCATTGCGATAGAGCGACAGGAAGTCGATGTT
TTCGAGGTTGAGCGGCGGAA

Product: DNA polymerase III, epsilon subunit

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 228; Mature: 228

Protein sequence:

>228_residues
MREIVLDTETTGFDPESGDRIVEIGAVELMGHVATGRTYHQYINPERSMPEEAFQVHGLGDDFLRDKPKFAEVGQAFLDF
IGDAKLVIHNAAFDIKFLNAELGWINLPKIPWEQAIDTLDIARKRFPGSPASLDALCRRFGIDNTSRTLHGALLDSEILA
EVYLELIGGRQPDFGLSNIPQKSAGDTSVDWTPRPRPTPLPSRITEEEAAAHADFVAKLGDDAVWLKT

Sequences:

>Translated_228_residues
MREIVLDTETTGFDPESGDRIVEIGAVELMGHVATGRTYHQYINPERSMPEEAFQVHGLGDDFLRDKPKFAEVGQAFLDF
IGDAKLVIHNAAFDIKFLNAELGWINLPKIPWEQAIDTLDIARKRFPGSPASLDALCRRFGIDNTSRTLHGALLDSEILA
EVYLELIGGRQPDFGLSNIPQKSAGDTSVDWTPRPRPTPLPSRITEEEAAAHADFVAKLGDDAVWLKT
>Mature_228_residues
MREIVLDTETTGFDPESGDRIVEIGAVELMGHVATGRTYHQYINPERSMPEEAFQVHGLGDDFLRDKPKFAEVGQAFLDF
IGDAKLVIHNAAFDIKFLNAELGWINLPKIPWEQAIDTLDIARKRFPGSPASLDALCRRFGIDNTSRTLHGALLDSEILA
EVYLELIGGRQPDFGLSNIPQKSAGDTSVDWTPRPRPTPLPSRITEEEAAAHADFVAKLGDDAVWLKT

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. The epsilon subunit contain the editing function and is a proofreading 3'-5' exonuclease [H]

COG id: COG0847

COG function: function code L; DNA polymerase III, epsilon subunit and related 3'-5' exonucleases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1786409, Length=235, Percent_Identity=46.3829787234043, Blast_Score=201, Evalue=4e-53,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006054
- InterPro:   IPR006309
- InterPro:   IPR006055
- InterPro:   IPR013520
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00929 Exonuc_X-T [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 25252; Mature: 25252

Theoretical pI: Translated: 4.56; Mature: 4.56

Prosite motif: PS00228 TUBULIN_B_AUTOREG

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREIVLDTETTGFDPESGDRIVEIGAVELMGHVATGRTYHQYINPERSMPEEAFQVHGLG
CCCEEECCCCCCCCCCCCCEEEEEHHHHHHHHHHCCCHHHHHCCCCCCCCHHHHEECCCC
DDFLRDKPKFAEVGQAFLDFIGDAKLVIHNAAFDIKFLNAELGWINLPKIPWEQAIDTLD
HHHHHCCCCHHHHHHHHHHHHCCCEEEEEECEEEEEEECCCCCEEECCCCCHHHHHHHHH
IARKRFPGSPASLDALCRRFGIDNTSRTLHGALLDSEILAEVYLELIGGRQPDFGLSNIP
HHHHHCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
QKSAGDTSVDWTPRPRPTPLPSRITEEEAAAHADFVAKLGDDAVWLKT
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEC
>Mature Secondary Structure
MREIVLDTETTGFDPESGDRIVEIGAVELMGHVATGRTYHQYINPERSMPEEAFQVHGLG
CCCEEECCCCCCCCCCCCCEEEEEHHHHHHHHHHCCCHHHHHCCCCCCCCHHHHEECCCC
DDFLRDKPKFAEVGQAFLDFIGDAKLVIHNAAFDIKFLNAELGWINLPKIPWEQAIDTLD
HHHHHCCCCHHHHHHHHHHHHCCCEEEEEECEEEEEEECCCCCEEECCCCCHHHHHHHHH
IARKRFPGSPASLDALCRRFGIDNTSRTLHGALLDSEILAEVYLELIGGRQPDFGLSNIP
HHHHHCCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
QKSAGDTSVDWTPRPRPTPLPSRITEEEAAAHADFVAKLGDDAVWLKT
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA