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The map label for this gene is ggtA [H]

Identifier: 110677447

GI number: 110677447

Start: 27764

End: 29341

Strand: Direct

Name: ggtA [H]

Synonym: RD1_0028

Alternate gene names: 110677447

Gene position: 27764-29341 (Clockwise)

Preceding gene: 110677446

Following gene: 110677449

Centisome position: 0.67

GC content: 59.57

Gene sequence:

>1578_bases
ATGCGCGATTTTCACCTTCCCGGCCGTTCCCCGGTTCTTGCCAGCAACGGCATGTGTGCCACATCACATCCGCTGGCTGC
AAAAACCGCGGTTGATGTTCTGCAACAAGGCGGCAATGCGATGGATGCCGCCATCGCGGGCGCTGTCCTGCTGGGCCTGT
GCGAACCGGCGATGACGGGTATTGGCGGTGATTGCTTTGTTCTTTGGTCTGATCGTGATCGCCAGAATGTGCGTGCGTTG
AACGGATCAGGACGCGCGCCCGCAGCTTTGGATGCGCATGATCTGCGCGAGGCCGGCGAAACCACCGTTCCATCCTTTTC
GGCCCATGCCGTGACCATTCCCACAGCGGTTGCCGCTTTTGCCCATCTGGCGGAAACAGTCGGCACCCTCGGTCTCGACA
GGCTGCTGGCGCCCTCGATCAAATACGCCCAGGAAGGTATCCCGGTCGCACCTCGCGTGGCCTTTGACTGGGAAAACTAT
GGCCACAACCTGCAAGGCAGTGCGCGGGAACAATACCTGATCGACGGAAAACTCCTGAAAACCGGTGATATCTTCCGCGC
CCCCGGTCAGGCGGAGGTCTTGCGCCGCATCGCCGAACAAGGCGCGTCGGCTTTTTACACCGGCGAAATTGCCGAAGACA
TGGTGGCCACTCTTCAGGCAGCGGGCGGTGTGCACACATTGGATGATTTCGCGGCCGCAGCCTGTGACGAGACCACGCCA
ATCTTCGGCACCTACAAGGACATCGACATCGTTGAACATCCCCCCAACGGTCAAGGGGCTACCGCGATCCTGATGCTCAA
CATCCTCGCGCAGTTTGACCTAGCGTCGATGGCGCCTTTTGGCACCCAACGCGCACATATCGAGGCAGAGGCGGCGAAAC
TGGCCTATGATGCCCGCAACCGTTTCCTTGCGGATGCCGATCATACCACGCGGCTGGCGCATATGCTGGATATGTCGCTT
GCCAAAAAACTGGCCGCGATGATTGATCCGGGCAAAGCGATGCCAGCGGCCGCCCCGTTGACGGAAATGGTCCACAAGGA
CACCGTCTATATTTCCACCGTGGACCGCGATGGAATGGCCGTGTCGCTGATCTATTCAATCTTCAAGGATTTCGGCTCGG
GCATCGCCTCTGATAAATTCGGGATTCTGTTACAGAACCGCGGGGCGGGATTTACGCTCGAACAGGGGCACCCGAATGAG
CTCAAGGGCGGCAAGCGTCCGATGCACACCATTATCCCTGCGATGCTGCGCAAGAACGGCAAGGTGATCATGCCGTTCGG
CGTCATGGGCGGGGCCTACCAGCCGAACGGACATGCGCGGTTTGTAACCAACCTCACCGACTTTGGCATGGACCCGCAAG
CGACCATTGATGCACCGCGCGCCTTTTCCGACATGGGCAATATGCAGGTTGAACGGGGCTATAGTGATGCAGTGCGCCAG
GAACTGACCGATCTGGGTCACTCGGTGAGCATACCCCAGACGGCAATCGGCGGGGCACAGGCGATCATGATGCATGACAA
TGGCGTTCTTGAGGGCGCGAGTGATCCGCGCAAAGATGGCTGCGCCCTGGGCTACTGA

Upstream 100 bases:

>100_bases
CTCCCCTTTGAGAACACTGATTTATCCCGTCATGGGTCGTGGACTTCCATCCCGAAGTCGCTAGTTTACGCGCAGAATTA
TCATGACCAAAGGCCCTCAC

Downstream 100 bases:

>100_bases
TCAAGCGCTCAGTTGAGCTGAAAATGCAACGGATAGCTGCCATCCTGTAGCGGGCCGAACAGATCGGGGATATCGGGGTG
ATCCACCGGTTCGCCTGAAT

Product: gamma-glutamyltranspeptidase, putative

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 525; Mature: 525

Protein sequence:

>525_residues
MRDFHLPGRSPVLASNGMCATSHPLAAKTAVDVLQQGGNAMDAAIAGAVLLGLCEPAMTGIGGDCFVLWSDRDRQNVRAL
NGSGRAPAALDAHDLREAGETTVPSFSAHAVTIPTAVAAFAHLAETVGTLGLDRLLAPSIKYAQEGIPVAPRVAFDWENY
GHNLQGSAREQYLIDGKLLKTGDIFRAPGQAEVLRRIAEQGASAFYTGEIAEDMVATLQAAGGVHTLDDFAAAACDETTP
IFGTYKDIDIVEHPPNGQGATAILMLNILAQFDLASMAPFGTQRAHIEAEAAKLAYDARNRFLADADHTTRLAHMLDMSL
AKKLAAMIDPGKAMPAAAPLTEMVHKDTVYISTVDRDGMAVSLIYSIFKDFGSGIASDKFGILLQNRGAGFTLEQGHPNE
LKGGKRPMHTIIPAMLRKNGKVIMPFGVMGGAYQPNGHARFVTNLTDFGMDPQATIDAPRAFSDMGNMQVERGYSDAVRQ
ELTDLGHSVSIPQTAIGGAQAIMMHDNGVLEGASDPRKDGCALGY

Sequences:

>Translated_525_residues
MRDFHLPGRSPVLASNGMCATSHPLAAKTAVDVLQQGGNAMDAAIAGAVLLGLCEPAMTGIGGDCFVLWSDRDRQNVRAL
NGSGRAPAALDAHDLREAGETTVPSFSAHAVTIPTAVAAFAHLAETVGTLGLDRLLAPSIKYAQEGIPVAPRVAFDWENY
GHNLQGSAREQYLIDGKLLKTGDIFRAPGQAEVLRRIAEQGASAFYTGEIAEDMVATLQAAGGVHTLDDFAAAACDETTP
IFGTYKDIDIVEHPPNGQGATAILMLNILAQFDLASMAPFGTQRAHIEAEAAKLAYDARNRFLADADHTTRLAHMLDMSL
AKKLAAMIDPGKAMPAAAPLTEMVHKDTVYISTVDRDGMAVSLIYSIFKDFGSGIASDKFGILLQNRGAGFTLEQGHPNE
LKGGKRPMHTIIPAMLRKNGKVIMPFGVMGGAYQPNGHARFVTNLTDFGMDPQATIDAPRAFSDMGNMQVERGYSDAVRQ
ELTDLGHSVSIPQTAIGGAQAIMMHDNGVLEGASDPRKDGCALGY
>Mature_525_residues
MRDFHLPGRSPVLASNGMCATSHPLAAKTAVDVLQQGGNAMDAAIAGAVLLGLCEPAMTGIGGDCFVLWSDRDRQNVRAL
NGSGRAPAALDAHDLREAGETTVPSFSAHAVTIPTAVAAFAHLAETVGTLGLDRLLAPSIKYAQEGIPVAPRVAFDWENY
GHNLQGSAREQYLIDGKLLKTGDIFRAPGQAEVLRRIAEQGASAFYTGEIAEDMVATLQAAGGVHTLDDFAAAACDETTP
IFGTYKDIDIVEHPPNGQGATAILMLNILAQFDLASMAPFGTQRAHIEAEAAKLAYDARNRFLADADHTTRLAHMLDMSL
AKKLAAMIDPGKAMPAAAPLTEMVHKDTVYISTVDRDGMAVSLIYSIFKDFGSGIASDKFGILLQNRGAGFTLEQGHPNE
LKGGKRPMHTIIPAMLRKNGKVIMPFGVMGGAYQPNGHARFVTNLTDFGMDPQATIDAPRAFSDMGNMQVERGYSDAVRQ
ELTDLGHSVSIPQTAIGGAQAIMMHDNGVLEGASDPRKDGCALGY

Specific function: GGT PLAYS A KEY ROLE IN THE GAMMA-GLUTAMYL CYCLE, A PATHWAY FOR THE SYNTHESIS AND DEGRADATION OF GLUTATHIONE. [C]

COG id: COG0405

COG function: function code E; Gamma-glutamyltransferase

Gene ontology:

Cell location: Periplasmic Protein [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the gamma-glutamyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI73915092, Length=561, Percent_Identity=28.3422459893048, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI73915090, Length=561, Percent_Identity=28.3422459893048, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI73915096, Length=561, Percent_Identity=28.3422459893048, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI73915094, Length=561, Percent_Identity=28.3422459893048, Blast_Score=150, Evalue=3e-36,
Organism=Homo sapiens, GI113429324, Length=532, Percent_Identity=27.8195488721804, Blast_Score=139, Evalue=5e-33,
Organism=Homo sapiens, GI113429326, Length=537, Percent_Identity=27.56052141527, Blast_Score=137, Evalue=2e-32,
Organism=Homo sapiens, GI109148539, Length=453, Percent_Identity=28.476821192053, Blast_Score=119, Evalue=9e-27,
Organism=Homo sapiens, GI153266885, Length=534, Percent_Identity=25.4681647940075, Blast_Score=107, Evalue=3e-23,
Organism=Homo sapiens, GI153266901, Length=535, Percent_Identity=25.4205607476636, Blast_Score=106, Evalue=6e-23,
Organism=Homo sapiens, GI153266907, Length=535, Percent_Identity=25.0467289719626, Blast_Score=92, Evalue=9e-19,
Organism=Escherichia coli, GI1789856, Length=541, Percent_Identity=32.902033271719, Blast_Score=234, Evalue=7e-63,
Organism=Caenorhabditis elegans, GI72000294, Length=480, Percent_Identity=24.375, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI212646519, Length=480, Percent_Identity=24.375, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17506189, Length=528, Percent_Identity=24.0530303030303, Blast_Score=109, Evalue=4e-24,
Organism=Caenorhabditis elegans, GI193208245, Length=547, Percent_Identity=23.5831809872029, Blast_Score=108, Evalue=8e-24,
Organism=Caenorhabditis elegans, GI193208247, Length=547, Percent_Identity=23.5831809872029, Blast_Score=108, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI17542894, Length=510, Percent_Identity=24.9019607843137, Blast_Score=103, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6323330, Length=548, Percent_Identity=22.0802919708029, Blast_Score=74, Evalue=8e-14,
Organism=Drosophila melanogaster, GI18859893, Length=491, Percent_Identity=26.2729124236253, Blast_Score=106, Evalue=3e-23,
Organism=Drosophila melanogaster, GI161077878, Length=538, Percent_Identity=23.7918215613383, Blast_Score=106, Evalue=4e-23,
Organism=Drosophila melanogaster, GI18859741, Length=536, Percent_Identity=23.3208955223881, Blast_Score=106, Evalue=5e-23,
Organism=Drosophila melanogaster, GI161077880, Length=538, Percent_Identity=23.7918215613383, Blast_Score=105, Evalue=5e-23,
Organism=Drosophila melanogaster, GI24642670, Length=538, Percent_Identity=23.7918215613383, Blast_Score=105, Evalue=6e-23,
Organism=Drosophila melanogaster, GI24642666, Length=538, Percent_Identity=23.7918215613383, Blast_Score=105, Evalue=6e-23,
Organism=Drosophila melanogaster, GI45551474, Length=538, Percent_Identity=23.7918215613383, Blast_Score=105, Evalue=6e-23,
Organism=Drosophila melanogaster, GI161077496, Length=452, Percent_Identity=24.5575221238938, Blast_Score=86, Evalue=5e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000101 [H]

Pfam domain/function: PF01019 G_glu_transpept [H]

EC number: =2.3.2.2 [H]

Molecular weight: Translated: 55652; Mature: 55652

Theoretical pI: Translated: 5.67; Mature: 5.67

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.2 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRDFHLPGRSPVLASNGMCATSHPLAAKTAVDVLQQGGNAMDAAIAGAVLLGLCEPAMTG
CCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHC
IGGDCFVLWSDRDRQNVRALNGSGRAPAALDAHDLREAGETTVPSFSAHAVTIPTAVAAF
CCCCEEEEECCCCCCCHHEECCCCCCCCCCCHHHHHHCCCCCCCCCCCCEEEHHHHHHHH
AHLAETVGTLGLDRLLAPSIKYAQEGIPVAPRVAFDWENYGHNLQGSAREQYLIDGKLLK
HHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCEEEECHHHCCCCCCCCCCCEEEECCEEEE
TGDIFRAPGQAEVLRRIAEQGASAFYTGEIAEDMVATLQAAGGVHTLDDFAAAACDETTP
CCCCEECCCHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCC
IFGTYKDIDIVEHPPNGQGATAILMLNILAQFDLASMAPFGTQRAHIEAEAAKLAYDARN
CEECCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHEEHHHHHHHHHHHHH
RFLADADHTTRLAHMLDMSLAKKLAAMIDPGKAMPAAAPLTEMVHKDTVYISTVDRDGMA
CEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCEEEEEEECCCCHH
VSLIYSIFKDFGSGIASDKFGILLQNRGAGFTLEQGHPNELKGGKRPMHTIIPAMLRKNG
HHHHHHHHHHHCCCCCCCCCEEEEECCCCCEEECCCCCHHCCCCCCCHHHHHHHHHHCCC
KVIMPFGVMGGAYQPNGHARFVTNLTDFGMDPQATIDAPRAFSDMGNMQVERGYSDAVRQ
CEEEEEECCCCCCCCCCCEEEEECHHHCCCCCCCCCCCCHHHHHHCCCEECCCHHHHHHH
ELTDLGHSVSIPQTAIGGAQAIMMHDNGVLEGASDPRKDGCALGY
HHHHCCCCCCCCHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRDFHLPGRSPVLASNGMCATSHPLAAKTAVDVLQQGGNAMDAAIAGAVLLGLCEPAMTG
CCCCCCCCCCCEEECCCCCCCCCCCHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHC
IGGDCFVLWSDRDRQNVRALNGSGRAPAALDAHDLREAGETTVPSFSAHAVTIPTAVAAF
CCCCEEEEECCCCCCCHHEECCCCCCCCCCCHHHHHHCCCCCCCCCCCCEEEHHHHHHHH
AHLAETVGTLGLDRLLAPSIKYAQEGIPVAPRVAFDWENYGHNLQGSAREQYLIDGKLLK
HHHHHHHHHHHHHHHHCCHHHHHHCCCCCCCEEEECHHHCCCCCCCCCCCEEEECCEEEE
TGDIFRAPGQAEVLRRIAEQGASAFYTGEIAEDMVATLQAAGGVHTLDDFAAAACDETTP
CCCCEECCCHHHHHHHHHHCCCCEEEEHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCC
IFGTYKDIDIVEHPPNGQGATAILMLNILAQFDLASMAPFGTQRAHIEAEAAKLAYDARN
CEECCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCHHEEHHHHHHHHHHHHH
RFLADADHTTRLAHMLDMSLAKKLAAMIDPGKAMPAAAPLTEMVHKDTVYISTVDRDGMA
CEECCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCEEEEEEECCCCHH
VSLIYSIFKDFGSGIASDKFGILLQNRGAGFTLEQGHPNELKGGKRPMHTIIPAMLRKNG
HHHHHHHHHHHCCCCCCCCCEEEEECCCCCEEECCCCCHHCCCCCCCHHHHHHHHHHCCC
KVIMPFGVMGGAYQPNGHARFVTNLTDFGMDPQATIDAPRAFSDMGNMQVERGYSDAVRQ
CEEEEEECCCCCCCCCCCEEEEECHHHCCCCCCCCCCCCHHHHHHCCCEECCCHHHHHHH
ELTDLGHSVSIPQTAIGGAQAIMMHDNGVLEGASDPRKDGCALGY
HHHHCCCCCCCCHHHCCCCEEEEEECCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9353933; 9384377 [H]