BacMap

Definition	Mycobacterium sp. MCS chromosome, complete genome.
Accession	NC_008146
Length	5,705,448

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The map label for this gene is fabG [H]

Identifier: 108801645

GI number: 108801645

Start: 4962370

End: 4963104

Strand: Reverse

Name: fabG [H]

Synonym: Mmcs_4682

Alternate gene names: 108801645

Gene position: 4963104-4962370 (Counterclockwise)

Preceding gene: 108801653

Following gene: 108801644

Centisome position: 86.99

GC content: 67.07

Gene sequence:

>735_bases
GTGGTGTTGGTGACCGGCGGCGTCCGCGGTGTCGGCGCCGGTATCAGTGCGGTGTTCGCAGCTCAGGGCGCCACGGTCGT
GACCTGCGCGCGTCGGCCGGTCGACGGCAGCCCCTACGAATTCCACCCCTGCGACATCCGCGACGACGACTCGGTGAAGT
CGCTGATCGACGCGATCGTCGGCGCGCACGGCCGCCTCGACGTGGTGATCAACAACGCCGGCGGTTCGCCCTACGTCCCC
GCCGCAGAGGCGTCGGCCAAGTTCAGCAGGAAGATCGTCGAGCTGAACCTGCTTGGCGCCCTGTCGGTTTCCACCCACGC
CAACGCCGTCATGCAGACCCAGGAGTCGGGTGGCTCCATCGTCAACATCACCAGCGTCAGTGCCAGACGCCCGACGCCGG
GCACCGTCGCATACGGTGCGGCCAAGGCCGGCGTGGAGAACATGACCACCACGCTCGCCGTCGAATGGGCGCCCAAGGTC
CGGGTGAACTCGGTCGTGGTCGGGATGGTCGAGACCGAGCAGGCCGAACTGTTCTACGGTGACGCCGACTCGATCGCCGC
GATCTCCCGCAACGTGCCGTTGGGTCGACTGGCCAAACCGGACGACATCGGCTGGGCGACAGCGTTTCTCGCGTCAGATG
CGGCGTCCTACATCAGCGGCGCATCGCTCGAGGTGCACGGTGGTGGCGAACCCCCGCACTACCTGTCGACCACCACCGCC
GACATCAAAAAGTAA

Upstream 100 bases:

>100_bases
GCATGCAAACTCCTGGGGGTCTCTACCTAAGCAAGCACTTGCTTGGTACGCTAGCACAGTGAGCGACGCCGCTGGAATCA
AACTGGGACTGGATGGCCGA

Downstream 100 bases:

>100_bases
GAGGAGACAACACATATGGGACTGCTCGACGGCCGCGTGGTCATCGTGACGGGTGCGGGCGGCGGCATCGGCCGTGCGCA
CGCACTGGCATTCGCCGCCG

Product: short chain dehydrogenase

Products: NA

Alternate protein names: 3-ketoacyl-acyl carrier protein reductase [H]

Number of amino acids: Translated: 244; Mature: 244

Protein sequence:

>244_residues
MVLVTGGVRGVGAGISAVFAAQGATVVTCARRPVDGSPYEFHPCDIRDDDSVKSLIDAIVGAHGRLDVVINNAGGSPYVP
AAEASAKFSRKIVELNLLGALSVSTHANAVMQTQESGGSIVNITSVSARRPTPGTVAYGAAKAGVENMTTTLAVEWAPKV
RVNSVVVGMVETEQAELFYGDADSIAAISRNVPLGRLAKPDDIGWATAFLASDAASYISGASLEVHGGGEPPHYLSTTTA
DIKK

Sequences:

>Translated_244_residues
MVLVTGGVRGVGAGISAVFAAQGATVVTCARRPVDGSPYEFHPCDIRDDDSVKSLIDAIVGAHGRLDVVINNAGGSPYVP
AAEASAKFSRKIVELNLLGALSVSTHANAVMQTQESGGSIVNITSVSARRPTPGTVAYGAAKAGVENMTTTLAVEWAPKV
RVNSVVVGMVETEQAELFYGDADSIAAISRNVPLGRLAKPDDIGWATAFLASDAASYISGASLEVHGGGEPPHYLSTTTA
DIKK
>Mature_244_residues
MVLVTGGVRGVGAGISAVFAAQGATVVTCARRPVDGSPYEFHPCDIRDDDSVKSLIDAIVGAHGRLDVVINNAGGSPYVP
AAEASAKFSRKIVELNLLGALSVSTHANAVMQTQESGGSIVNITSVSARRPTPGTVAYGAAKAGVENMTTTLAVEWAPKV
RVNSVVVGMVETEQAELFYGDADSIAAISRNVPLGRLAKPDDIGWATAFLASDAASYISGASLEVHGGGEPPHYLSTTTA
DIKK

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the short-chain dehydrogenases/reductases (SDR) family [H]

Homologues:

Organism=Homo sapiens, GI19923817, Length=247, Percent_Identity=31.9838056680162, Blast_Score=111, Evalue=6e-25,
Organism=Homo sapiens, GI59889578, Length=225, Percent_Identity=35.5555555555556, Blast_Score=103, Evalue=1e-22,
Organism=Homo sapiens, GI32483357, Length=242, Percent_Identity=28.5123966942149, Blast_Score=101, Evalue=6e-22,
Organism=Homo sapiens, GI10190704, Length=240, Percent_Identity=32.0833333333333, Blast_Score=98, Evalue=6e-21,
Organism=Homo sapiens, GI4503301, Length=192, Percent_Identity=30.2083333333333, Blast_Score=91, Evalue=1e-18,
Organism=Homo sapiens, GI15277342, Length=248, Percent_Identity=29.8387096774194, Blast_Score=89, Evalue=4e-18,
Organism=Homo sapiens, GI7705925, Length=236, Percent_Identity=27.5423728813559, Blast_Score=83, Evalue=3e-16,
Organism=Homo sapiens, GI40254992, Length=235, Percent_Identity=28.0851063829787, Blast_Score=82, Evalue=5e-16,
Organism=Homo sapiens, GI126723750, Length=245, Percent_Identity=25.3061224489796, Blast_Score=81, Evalue=9e-16,
Organism=Homo sapiens, GI5031737, Length=238, Percent_Identity=26.0504201680672, Blast_Score=80, Evalue=2e-15,
Organism=Homo sapiens, GI109715829, Length=236, Percent_Identity=28.8135593220339, Blast_Score=73, Evalue=3e-13,
Organism=Escherichia coli, GI87082100, Length=256, Percent_Identity=30.859375, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1789208, Length=236, Percent_Identity=29.6610169491525, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI1787335, Length=237, Percent_Identity=33.3333333333333, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI2367175, Length=245, Percent_Identity=28.1632653061224, Blast_Score=88, Evalue=5e-19,
Organism=Escherichia coli, GI1788459, Length=174, Percent_Identity=33.3333333333333, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1787905, Length=240, Percent_Identity=30.4166666666667, Blast_Score=85, Evalue=5e-18,
Organism=Escherichia coli, GI1786812, Length=237, Percent_Identity=27.8481012658228, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1789378, Length=251, Percent_Identity=27.4900398406374, Blast_Score=77, Evalue=9e-16,
Organism=Escherichia coli, GI1790717, Length=239, Percent_Identity=23.8493723849372, Blast_Score=71, Evalue=8e-14,
Organism=Escherichia coli, GI2367365, Length=242, Percent_Identity=28.5123966942149, Blast_Score=66, Evalue=2e-12,
Organism=Escherichia coli, GI87082160, Length=241, Percent_Identity=25.3112033195021, Blast_Score=65, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI17561272, Length=237, Percent_Identity=33.7552742616034, Blast_Score=109, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17536651, Length=251, Percent_Identity=32.2709163346614, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17536025, Length=249, Percent_Identity=31.3253012048193, Blast_Score=103, Evalue=1e-22,
Organism=Caenorhabditis elegans, GI25147288, Length=240, Percent_Identity=31.25, Blast_Score=98, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17560676, Length=241, Percent_Identity=29.045643153527, Blast_Score=94, Evalue=6e-20,
Organism=Caenorhabditis elegans, GI17561402, Length=244, Percent_Identity=28.6885245901639, Blast_Score=93, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17562910, Length=278, Percent_Identity=28.4172661870504, Blast_Score=88, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI17555706, Length=241, Percent_Identity=30.7053941908714, Blast_Score=82, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI17559104, Length=259, Percent_Identity=27.7992277992278, Blast_Score=82, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI115534694, Length=236, Percent_Identity=27.5423728813559, Blast_Score=81, Evalue=5e-16,
Organism=Caenorhabditis elegans, GI17544670, Length=261, Percent_Identity=26.8199233716475, Blast_Score=77, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI71994600, Length=246, Percent_Identity=25.2032520325203, Blast_Score=77, Evalue=9e-15,
Organism=Caenorhabditis elegans, GI17562904, Length=260, Percent_Identity=27.3076923076923, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI17560332, Length=265, Percent_Identity=28.6792452830189, Blast_Score=76, Evalue=2e-14,
Organism=Caenorhabditis elegans, GI71994604, Length=189, Percent_Identity=28.042328042328, Blast_Score=75, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI193204405, Length=254, Percent_Identity=27.9527559055118, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17538480, Length=265, Percent_Identity=25.6603773584906, Blast_Score=72, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI72000259, Length=261, Percent_Identity=28.3524904214559, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17551412, Length=261, Percent_Identity=26.4367816091954, Blast_Score=70, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17538182, Length=248, Percent_Identity=26.2096774193548, Blast_Score=69, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17562908, Length=255, Percent_Identity=27.4509803921569, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17531453, Length=255, Percent_Identity=26.2745098039216, Blast_Score=68, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17562906, Length=256, Percent_Identity=27.34375, Blast_Score=67, Evalue=9e-12,
Organism=Caenorhabditis elegans, GI17560220, Length=260, Percent_Identity=26.9230769230769, Blast_Score=66, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17562990, Length=260, Percent_Identity=25.3846153846154, Blast_Score=65, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17560150, Length=258, Percent_Identity=25.5813953488372, Blast_Score=64, Evalue=5e-11,
Organism=Saccharomyces cerevisiae, GI6324126, Length=186, Percent_Identity=31.1827956989247, Blast_Score=81, Evalue=2e-16,
Organism=Drosophila melanogaster, GI21357041, Length=246, Percent_Identity=32.9268292682927, Blast_Score=103, Evalue=9e-23,
Organism=Drosophila melanogaster, GI28571526, Length=254, Percent_Identity=30.7086614173228, Blast_Score=98, Evalue=4e-21,
Organism=Drosophila melanogaster, GI23397609, Length=243, Percent_Identity=30.0411522633745, Blast_Score=96, Evalue=2e-20,
Organism=Drosophila melanogaster, GI24643142, Length=235, Percent_Identity=28.5106382978723, Blast_Score=90, Evalue=1e-18,
Organism=Drosophila melanogaster, GI21355319, Length=240, Percent_Identity=26.6666666666667, Blast_Score=86, Evalue=2e-17,
Organism=Drosophila melanogaster, GI24644339, Length=245, Percent_Identity=30.2040816326531, Blast_Score=84, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24644337, Length=173, Percent_Identity=32.3699421965318, Blast_Score=83, Evalue=2e-16,
Organism=Drosophila melanogaster, GI24639444, Length=239, Percent_Identity=28.8702928870293, Blast_Score=80, Evalue=9e-16,
Organism=Drosophila melanogaster, GI116007236, Length=199, Percent_Identity=29.6482412060301, Blast_Score=74, Evalue=1e-13,
Organism=Drosophila melanogaster, GI116007238, Length=218, Percent_Identity=25.6880733944954, Blast_Score=66, Evalue=2e-11,
Organism=Drosophila melanogaster, GI116007234, Length=252, Percent_Identity=26.1904761904762, Blast_Score=65, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011284
- InterPro:   IPR002198
- InterPro:   IPR002347
- InterPro:   IPR016040
- InterPro:   IPR020904 [H]

Pfam domain/function: PF00106 adh_short [H]

EC number: =1.1.1.100 [H]

Molecular weight: Translated: 25063; Mature: 25063

Theoretical pI: Translated: 5.61; Mature: 5.61

Prosite motif: PS00061 ADH_SHORT

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLVTGGVRGVGAGISAVFAAQGATVVTCARRPVDGSPYEFHPCDIRDDDSVKSLIDAIV
CEEEECCCCCCCCCHHHHHHCCCCEEEEEECCCCCCCCCEECCCCCCCCHHHHHHHHHHH
GAHGRLDVVINNAGGSPYVPAAEASAKFSRKIVELNLLGALSVSTHANAVMQTQESGGSI
CCCCEEEEEEECCCCCCCCCCCCHHHHHHHEEEEEEEEEEEEECCCCCEEEEECCCCCCE
VNITSVSARRPTPGTVAYGAAKAGVENMTTTLAVEWAPKVRVNSVVVGMVETEQAELFYG
EEEEECCCCCCCCCCEEECCHHCCCCCCEEEEEEEECCCEEECEEEEEEEECCCEEEEEC
DADSIAAISRNVPLGRLAKPDDIGWATAFLASDAASYISGASLEVHGGGEPPHYLSTTTA
CCCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCEEECCCH
DIKK
HCCC
>Mature Secondary Structure
MVLVTGGVRGVGAGISAVFAAQGATVVTCARRPVDGSPYEFHPCDIRDDDSVKSLIDAIV
CEEEECCCCCCCCCHHHHHHCCCCEEEEEECCCCCCCCCEECCCCCCCCHHHHHHHHHHH
GAHGRLDVVINNAGGSPYVPAAEASAKFSRKIVELNLLGALSVSTHANAVMQTQESGGSI
CCCCEEEEEEECCCCCCCCCCCCHHHHHHHEEEEEEEEEEEEECCCCCEEEEECCCCCCE
VNITSVSARRPTPGTVAYGAAKAGVENMTTTLAVEWAPKVRVNSVVVGMVETEQAELFYG
EEEEECCCCCCCCCCEEECCHHCCCCCCEEEEEEEECCCEEECEEEEEEEECCCEEEEEC
DADSIAAISRNVPLGRLAKPDDIGWATAFLASDAASYISGASLEVHGGGEPPHYLSTTTA
CCCCCHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCEEECCCH
DIKK
HCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10360571 [H]