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The map label for this gene is plsB [H]

Identifier: 108800584

GI number: 108800584

Start: 3860654

End: 3863026

Strand: Reverse

Name: plsB [H]

Synonym: Mmcs_3618

Alternate gene names: 108800584

Gene position: 3863026-3860654 (Counterclockwise)

Preceding gene: 108800585

Following gene: 108800583

Centisome position: 67.71

GC content: 67.59

Gene sequence:

>2373_bases
GTGAAGCTGCCCGACGACTACTACGCCAGCTTCACCACCACGGACGACGCGCTGGTGCTGGCCGCCGCGTCGTCGCCGGC
CGAGGTGGAACTGCTCGACGAGTGGCTGGCCGCCCAACGCCACGACAACCCCGACGTCGAGGTCGACGTGCTGCAGCTAC
CCGTCGACGGGGAACCGTCGCCCGGCGTCCTCGCCAAACTGGTCGAAGAACTCGAGGCCGACGAGGACCGCACTGTCGTG
CCGGTGCGGGTGTTCTGGGTGCCCGCGGGTCTGCCCACGCGGTCGAAGGTGGTGGCGCTGATCTCCGGTCGCGACACCTA
CCGTCCACCCGAGATCCTGCAGCGCCGCATCCTCAAACGTGACCGGACCCGGGCCCGCGTCATCGCCGGTGAACCCGCCA
AGGTCTCCGAACTCCGTCAGCAGTGGCACGACCACACCGTCGCCGAGAACCCACGCGATTTCGCGCATTTCGTCGTCCGC
CGCGCGGTGCTGGCGATCGAGCGCGTCGAGTACCGGCTGCTGGGCCCCGAGTACAAGTCGCCCCGGCTGGTGAAGCCGGA
GATCCTCGCCTCCACCAAATTCCGTGCCGGACTGGAGAAGATCCCCGGTGCGACGGTGGACGAGGCAGGCAAGATGCTCG
ACGAACTGGCCACCGGGTGGAGCCGGGTGTCGGTGGACCTCATCCCGAACCTCAGCCGGCTGATCGTCAAACGGGGCTTC
GACACCAACATCGACTACGACCACACCGAGATCGCCAGGCTGCGAAGCGATCTGGAGAACCATCCGGCGGTGCTGCTGTT
CTCTCACCGGTCGTATCTCGACGGCGGTGTCGTCCCCGTCGCGATGCAGGAGAACCGGCTGCCCCCGGTGCACATGTTCG
CCGGCATCAACCTGTCCTTCGGTTTCATGGGGCCGCTGCTGCGTCGGTCCGGCGTGATCTTCATCCGCCGCAACGTCGCC
GGAGACCCCCTGTACAAGTACGTGCTCAAGGAGTACGTCGGCTACGTCGTGCAGAAGCGGTTCAACCTCAGCTGGTCCAT
CGAGGGCACCCGGTCGCGCACCGGGAAGATGCTGCCCCCCAAGCTCGGTCTGCTTGCCTACGTCGCCGACGCGTACCTCG
CCGGCCGCAGCGACGACATCCTGCTGCAGCCGGTGTCGATCAGTTTCGATCAGCTGCACGAGATCTCCGAGTACGCCGAC
TACGCCCGCGGGGGCGAGAAGACCCCGGAGGGGCTGAGCTGGCTGTACAACTACATCAAGGCGCAGGGGGAGCGAAGCTA
CGGCAAGATCTATGTCCGCTTCCCCGAAGCGGTTTCGATGCGCCAGTACCTCGGTGAACCCGGTGGCCCGATCGCGACCG
ACGAGTCCGCCAAACGGCTCGCGATGCAGAAGATGGCCTTCGAAGTGGCCTGGCGCATCCTGCAGGTGACGCCGATCAAC
GCGACCGCACTGGTGTCGGGACTGCTGCTGACCACCCGCGGCGTCGCACTCACCCTCGACCAGCTGCACCACACCCTGCA
GGACGGGCTCGACTACCTGATGCGCAAGGACAAGCCGCTGACCAACAGCGCGCTGCGCCTGCGCACCCCCGAGGGGGTGC
AGGCCGCGGTCGATGCGTTGTCCAACGGCCACCCCGTCACCAAGGTGGACAGTGGTCGCGAACCGGTCTGGTACATCGCG
GCCGACGACGAGCACGAGGCGGCGTTCTACCGCAACACCCTCATCCACGCGTTCCTCGAGACGTCGATCGTGGAGTTGGC
GCTGGGGTACGCCGCACGCGCGGACGGGGATCCGCTGGAGGCGTTCTGGACACAGGCGGCACGGTTGCGCGATCTTCTGA
AGTTCGACTTCTACTTCGCCGACTCGGCGGCGTTCCGCGAGCACGTCGTCGAGGAGATGTCGTGGCGGGCCGACTGGGAG
TCGCAGGTGGCCGCCGGAGGTGAGCGGATCGACGCACTGCTGCGGGAGAAGCGGCCCCTGATGGCCGGCGCGATGCTGCG
GCCGTTCTTCGAGGCCTACGAGATCCTGGCGAGCGCCCTGCGCGACGCCCCGGCCGACATCGAGGAGAAGGACCTCATCA
AGCGGGCCATGGGGTTGGGCCGCCAGTACGTCGCGCAGGACCGGGTGCGCAGCAACGAGTCGGTGTCGGCACTGCTGTTC
AGCACCGCCCGGCAGGTCGCCGCCGATCAGCACCTGCTGGAATCCGGTCCGGACCTCGAGGTGCGGCGTACGGCGTTCTG
TGAGGAGCTGGGCGGGATCCTGGCCGACATGGACAAGGTCGACCGGTACGCCCGCGAGCAGTTCATGGCGCGGGAGGCCG
AACGTCACCGGGCCAAGACGGGTCGAGCCGCGGTGAACCGCCCGGCAGGGTGA

Upstream 100 bases:

>100_bases
CGGCGAAGAAGACGCCGGCGAAGAAGGCCGCCAAGACCGCTGAGCCGCAACCGAAAACGTCGGCCAACGGCAGGTCGCAG
CCCGGGGTGAAAGGTCGACA

Downstream 100 bases:

>100_bases
CGCCGAACACGCCATACCCTGGGAACATGACCACGGTTGCGGTGAAGACACGCCCCAGCGCGGTGTGGCCCGTGCTGGTG
GGCGTGGCCGCCCTGGCCGG

Product: glycerol-3-phosphate acyltransferase

Products: NA

Alternate protein names: GPAT [H]

Number of amino acids: Translated: 790; Mature: 790

Protein sequence:

>790_residues
MKLPDDYYASFTTTDDALVLAAASSPAEVELLDEWLAAQRHDNPDVEVDVLQLPVDGEPSPGVLAKLVEELEADEDRTVV
PVRVFWVPAGLPTRSKVVALISGRDTYRPPEILQRRILKRDRTRARVIAGEPAKVSELRQQWHDHTVAENPRDFAHFVVR
RAVLAIERVEYRLLGPEYKSPRLVKPEILASTKFRAGLEKIPGATVDEAGKMLDELATGWSRVSVDLIPNLSRLIVKRGF
DTNIDYDHTEIARLRSDLENHPAVLLFSHRSYLDGGVVPVAMQENRLPPVHMFAGINLSFGFMGPLLRRSGVIFIRRNVA
GDPLYKYVLKEYVGYVVQKRFNLSWSIEGTRSRTGKMLPPKLGLLAYVADAYLAGRSDDILLQPVSISFDQLHEISEYAD
YARGGEKTPEGLSWLYNYIKAQGERSYGKIYVRFPEAVSMRQYLGEPGGPIATDESAKRLAMQKMAFEVAWRILQVTPIN
ATALVSGLLLTTRGVALTLDQLHHTLQDGLDYLMRKDKPLTNSALRLRTPEGVQAAVDALSNGHPVTKVDSGREPVWYIA
ADDEHEAAFYRNTLIHAFLETSIVELALGYAARADGDPLEAFWTQAARLRDLLKFDFYFADSAAFREHVVEEMSWRADWE
SQVAAGGERIDALLREKRPLMAGAMLRPFFEAYEILASALRDAPADIEEKDLIKRAMGLGRQYVAQDRVRSNESVSALLF
STARQVAADQHLLESGPDLEVRRTAFCEELGGILADMDKVDRYAREQFMAREAERHRAKTGRAAVNRPAG

Sequences:

>Translated_790_residues
MKLPDDYYASFTTTDDALVLAAASSPAEVELLDEWLAAQRHDNPDVEVDVLQLPVDGEPSPGVLAKLVEELEADEDRTVV
PVRVFWVPAGLPTRSKVVALISGRDTYRPPEILQRRILKRDRTRARVIAGEPAKVSELRQQWHDHTVAENPRDFAHFVVR
RAVLAIERVEYRLLGPEYKSPRLVKPEILASTKFRAGLEKIPGATVDEAGKMLDELATGWSRVSVDLIPNLSRLIVKRGF
DTNIDYDHTEIARLRSDLENHPAVLLFSHRSYLDGGVVPVAMQENRLPPVHMFAGINLSFGFMGPLLRRSGVIFIRRNVA
GDPLYKYVLKEYVGYVVQKRFNLSWSIEGTRSRTGKMLPPKLGLLAYVADAYLAGRSDDILLQPVSISFDQLHEISEYAD
YARGGEKTPEGLSWLYNYIKAQGERSYGKIYVRFPEAVSMRQYLGEPGGPIATDESAKRLAMQKMAFEVAWRILQVTPIN
ATALVSGLLLTTRGVALTLDQLHHTLQDGLDYLMRKDKPLTNSALRLRTPEGVQAAVDALSNGHPVTKVDSGREPVWYIA
ADDEHEAAFYRNTLIHAFLETSIVELALGYAARADGDPLEAFWTQAARLRDLLKFDFYFADSAAFREHVVEEMSWRADWE
SQVAAGGERIDALLREKRPLMAGAMLRPFFEAYEILASALRDAPADIEEKDLIKRAMGLGRQYVAQDRVRSNESVSALLF
STARQVAADQHLLESGPDLEVRRTAFCEELGGILADMDKVDRYAREQFMAREAERHRAKTGRAAVNRPAG
>Mature_790_residues
MKLPDDYYASFTTTDDALVLAAASSPAEVELLDEWLAAQRHDNPDVEVDVLQLPVDGEPSPGVLAKLVEELEADEDRTVV
PVRVFWVPAGLPTRSKVVALISGRDTYRPPEILQRRILKRDRTRARVIAGEPAKVSELRQQWHDHTVAENPRDFAHFVVR
RAVLAIERVEYRLLGPEYKSPRLVKPEILASTKFRAGLEKIPGATVDEAGKMLDELATGWSRVSVDLIPNLSRLIVKRGF
DTNIDYDHTEIARLRSDLENHPAVLLFSHRSYLDGGVVPVAMQENRLPPVHMFAGINLSFGFMGPLLRRSGVIFIRRNVA
GDPLYKYVLKEYVGYVVQKRFNLSWSIEGTRSRTGKMLPPKLGLLAYVADAYLAGRSDDILLQPVSISFDQLHEISEYAD
YARGGEKTPEGLSWLYNYIKAQGERSYGKIYVRFPEAVSMRQYLGEPGGPIATDESAKRLAMQKMAFEVAWRILQVTPIN
ATALVSGLLLTTRGVALTLDQLHHTLQDGLDYLMRKDKPLTNSALRLRTPEGVQAAVDALSNGHPVTKVDSGREPVWYIA
ADDEHEAAFYRNTLIHAFLETSIVELALGYAARADGDPLEAFWTQAARLRDLLKFDFYFADSAAFREHVVEEMSWRADWE
SQVAAGGERIDALLREKRPLMAGAMLRPFFEAYEILASALRDAPADIEEKDLIKRAMGLGRQYVAQDRVRSNESVSALLF
STARQVAADQHLLESGPDLEVRRTAFCEELGGILADMDKVDRYAREQFMAREAERHRAKTGRAAVNRPAG

Specific function: De novo phospholipid biosynthesis; first step. [C]

COG id: COG2937

COG function: function code I; Glycerol-3-phosphate O-acyltransferase

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein; Cytoplasmic side [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPAT/DAPAT family [H]

Homologues:

Organism=Homo sapiens, GI7657134, Length=508, Percent_Identity=26.1811023622047, Blast_Score=117, Evalue=6e-26,
Organism=Homo sapiens, GI190358539, Length=414, Percent_Identity=23.9130434782609, Blast_Score=90, Evalue=9e-18,
Organism=Escherichia coli, GI87082362, Length=388, Percent_Identity=28.0927835051546, Blast_Score=130, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI71988723, Length=579, Percent_Identity=24.006908462867, Blast_Score=100, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI25147672, Length=285, Percent_Identity=29.1228070175439, Blast_Score=97, Evalue=3e-20,
Organism=Caenorhabditis elegans, GI71988728, Length=572, Percent_Identity=23.2517482517483, Blast_Score=97, Evalue=3e-20,
Organism=Drosophila melanogaster, GI17864692, Length=286, Percent_Identity=27.6223776223776, Blast_Score=110, Evalue=5e-24,
Organism=Drosophila melanogaster, GI24650754, Length=211, Percent_Identity=30.3317535545024, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI24650752, Length=211, Percent_Identity=30.3317535545024, Blast_Score=92, Evalue=1e-18,
Organism=Drosophila melanogaster, GI21357731, Length=211, Percent_Identity=30.3317535545024, Blast_Score=92, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002123
- InterPro:   IPR022284 [H]

Pfam domain/function: PF01553 Acyltransferase [H]

EC number: =2.3.1.15 [H]

Molecular weight: Translated: 88573; Mature: 88573

Theoretical pI: Translated: 6.20; Mature: 6.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLPDDYYASFTTTDDALVLAAASSPAEVELLDEWLAAQRHDNPDVEVDVLQLPVDGEPS
CCCCCCCCCEEECCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCC
PGVLAKLVEELEADEDRTVVPVRVFWVPAGLPTRSKVVALISGRDTYRPPEILQRRILKR
CCHHHHHHHHHCCCCCCEEEEEEEEEEECCCCCCCCEEEEEECCCCCCCHHHHHHHHHHH
DRTRARVIAGEPAKVSELRQQWHDHTVAENPRDFAHFVVRRAVLAIERVEYRLLGPEYKS
CCCCEEEECCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCC
PRLVKPEILASTKFRAGLEKIPGATVDEAGKMLDELATGWSRVSVDLIPNLSRLIVKRGF
CCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHEEEEHHCCCHHHHHHHCCC
DTNIDYDHTEIARLRSDLENHPAVLLFSHRSYLDGGVVPVAMQENRLPPVHMFAGINLSF
CCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEEEECCCCCCCEEEEECCCCCH
GFMGPLLRRSGVIFIRRNVAGDPLYKYVLKEYVGYVVQKRFNLSWSIEGTRSRTGKMLPP
HHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCC
KLGLLAYVADAYLAGRSDDILLQPVSISFDQLHEISEYADYARGGEKTPEGLSWLYNYIK
HHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
AQGERSYGKIYVRFPEAVSMRQYLGEPGGPIATDESAKRLAMQKMAFEVAWRILQVTPIN
HCCCCCCCEEEEECCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
ATALVSGLLLTTRGVALTLDQLHHTLQDGLDYLMRKDKPLTNSALRLRTPEGVQAAVDAL
HHHHHHHHHHHHCCHHEEHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHH
SNGHPVTKVDSGREPVWYIAADDEHEAAFYRNTLIHAFLETSIVELALGYAARADGDPLE
CCCCCCCEECCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
AFWTQAARLRDLLKFDFYFADSAAFREHVVEEMSWRADWESQVAAGGERIDALLREKRPL
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHCCCH
MAGAMLRPFFEAYEILASALRDAPADIEEKDLIKRAMGLGRQYVAQDRVRSNESVSALLF
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHH
STARQVAADQHLLESGPDLEVRRTAFCEELGGILADMDKVDRYAREQFMAREAERHRAKT
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GRAAVNRPAG
CCCCCCCCCC
>Mature Secondary Structure
MKLPDDYYASFTTTDDALVLAAASSPAEVELLDEWLAAQRHDNPDVEVDVLQLPVDGEPS
CCCCCCCCCEEECCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCC
PGVLAKLVEELEADEDRTVVPVRVFWVPAGLPTRSKVVALISGRDTYRPPEILQRRILKR
CCHHHHHHHHHCCCCCCEEEEEEEEEEECCCCCCCCEEEEEECCCCCCCHHHHHHHHHHH
DRTRARVIAGEPAKVSELRQQWHDHTVAENPRDFAHFVVRRAVLAIERVEYRLLGPEYKS
CCCCEEEECCCCHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCC
PRLVKPEILASTKFRAGLEKIPGATVDEAGKMLDELATGWSRVSVDLIPNLSRLIVKRGF
CCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHEEEEHHCCCHHHHHHHCCC
DTNIDYDHTEIARLRSDLENHPAVLLFSHRSYLDGGVVPVAMQENRLPPVHMFAGINLSF
CCCCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCCEEEEECCCCCCCEEEEECCCCCH
GFMGPLLRRSGVIFIRRNVAGDPLYKYVLKEYVGYVVQKRFNLSWSIEGTRSRTGKMLPP
HHHHHHHHHCCEEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCC
KLGLLAYVADAYLAGRSDDILLQPVSISFDQLHEISEYADYARGGEKTPEGLSWLYNYIK
HHHHHHHHHHHHHCCCCCCEEEEECCCCHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHH
AQGERSYGKIYVRFPEAVSMRQYLGEPGGPIATDESAKRLAMQKMAFEVAWRILQVTPIN
HCCCCCCCEEEEECCHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
ATALVSGLLLTTRGVALTLDQLHHTLQDGLDYLMRKDKPLTNSALRLRTPEGVQAAVDAL
HHHHHHHHHHHHCCHHEEHHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCHHHHHHHHH
SNGHPVTKVDSGREPVWYIAADDEHEAAFYRNTLIHAFLETSIVELALGYAARADGDPLE
CCCCCCCEECCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHH
AFWTQAARLRDLLKFDFYFADSAAFREHVVEEMSWRADWESQVAAGGERIDALLREKRPL
HHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCHHHHHCCHHHHHHHHHHCCCH
MAGAMLRPFFEAYEILASALRDAPADIEEKDLIKRAMGLGRQYVAQDRVRSNESVSALLF
HHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCHHHHHHHHHCCCCHHHHHHH
STARQVAADQHLLESGPDLEVRRTAFCEELGGILADMDKVDRYAREQFMAREAERHRAKT
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
GRAAVNRPAG
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA