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The map label for this gene is plsC [C]

Identifier: 108800585

GI number: 108800585

Start: 3863023

End: 3864708

Strand: Reverse

Name: plsC [C]

Synonym: Mmcs_3619

Alternate gene names: 108800585

Gene position: 3864708-3863023 (Counterclockwise)

Preceding gene: 108800586

Following gene: 108800584

Centisome position: 67.74

GC content: 67.32

Gene sequence:

>1686_bases
ATGAGTCCGGACGACGGTCAGCAGTCCGAGCGGCGTCCCATGCGTCTGCCCGGGTCGGTCGCGGAGATCCTCGCCGCACC
GGAGGGGCCGCAGGTCGGCGCGTTCTTCGATCTCGACGGCACGCTGGTGGCCGGGTTCACCGGCGTCATCATGACCCGGG
ACCGGTTGCGCCGCAGGCAGATGAGCGTGGGGGAGTTCATCGGCATGGTGCAGGCCGGGCTCAACCACCAACTCGGCCGG
TCGGAGTTCGAAGACCTCATCGGCAAGGGCGCGCGCATGCTACGCGGCAGTTCGCTCAGCGACATCGACGAACTCGCCGA
ACGCCTCTTCCTGCAGCACGTCCGCGACCGCATCTATCCCGAGATGCGCGCGCTGGTCCGTGCGCACATGGCGCGGGGTC
ACACCGTCGTGCTCAGTTCGTCGGCGCTGACGGTGCAGGTCGAACCCGTGGCCCGGTACCTCGGCATCCAGAACGTGCTG
AGCAACAAGTTCGAGACCGACGACAACGGGTGCATCACCGGTGAGGTGGTCCGGCCCATCCTGTGGGGGCCGGGGAAAGC
CCATGCGGTGCAGGCGTTCGCGGCCCGCAACGGCGTCGACCTGTCGAAGAGCTACTTCTACGCCGACGGGGACGAGGACG
TCGCGCTGATGTACCTCGTCGGCAACCCGCGGCCCACCAACCCGGCGGGCAAGCTCGCCGCCGTCGCCGCCAAGCGCGGG
TGGCCGGTGCTGCGGTTCAGCAGCCGCAGCGGTAGCAGTCCACTCTCCCAGCTGCGCACGGTCGCCGGCATCGGATCGGT
TTTGCCGGTCGCCGCCAGCGCGCTCGGCGTGGGACTGCTCACCCGCAACAGGCGTACCGGGGTGAACTTCTTCACCTCGA
CGTGGAGCCGGTTGCTGCTCACCACTGCCGGCATCAACCTCAACGTGCTCGGCCGGGAGAACCTGACCGCACAGCGCCCC
GCGGTGTTCATCTTCAACCACCGCAATCAGGCCGACCCGCTCATCGCGGGCAGGCTGGTCGAGACCGACTTCACGGCGGT
GGGCAAGAAGGAACTCGAGAACGACCCACTGATCGGCACCATCGGCAAGGTGATGGACGCGGCGTTCATCGACCGCGACG
ATCCCAAGGCCGCCGTCGAAGGTCTTCGCAAGGTCGAAGAGCTTGCCGGAAAGGGTCTTTCGATCCTGATCGCGCCCGAG
GGCACCCGCCTGGACACCACCGAGGTCGGGGAGTTCAAGAAGGGTCCGTTCCGCATCGCCATGTCGGCGCGGATACCGAT
CGTGCCGATCGTCATCCGCAACGCGGAGGTCGTCGCCGCGCGTGATTCGAGCACCTTCAATCCCGGCACCGTCGACATCG
CGGTCTATCCGCCCATCCCGACCGAGGACTGGACGCTGCAGGATCTGCCCGACCGCATCGCCGAGATTCGGCAGATCTAC
CTCGACACCCTCAAGGCGTGGCCACACGGAAACCTGCCGGTCCCCGCCCTCTACAAACGGTCGCCGGGGGAGGCGGTGGA
GCCACGCAAGGTCGAGGACAAGCCGGCCAAGAAGGCCGCCAAGAAGGCCGCCAAGAAAACACCGGCGAAGAAGACGCCGG
CGAAGAAGGCCGCCAAGACCGCTGAGCCGCAACCGAAAACGTCGGCCAACGGCAGGTCGCAGCCCGGGGTGAAAGGTCGA
CAGTGA

Upstream 100 bases:

>100_bases
GTTTCGACGAGGTGCTCGCCATCGGCGGTCCCGGCCGCGCCAGCCCGGCGTCGTTCACCCTGGAGTCCGAAAAACCGTCA
CCGAATGGGAGTGCGCCACA

Downstream 100 bases:

>100_bases
AGCTGCCCGACGACTACTACGCCAGCTTCACCACCACGGACGACGCGCTGGTGCTGGCCGCCGCGTCGTCGCCGGCCGAG
GTGGAACTGCTCGACGAGTG

Product: 1-acyl-sn-glycerol-3-phosphate acyltransferase

Products: CoA; 1,2-diacyl-sn-glycerol 3-phosphate

Alternate protein names: NA

Number of amino acids: Translated: 561; Mature: 560

Protein sequence:

>561_residues
MSPDDGQQSERRPMRLPGSVAEILAAPEGPQVGAFFDLDGTLVAGFTGVIMTRDRLRRRQMSVGEFIGMVQAGLNHQLGR
SEFEDLIGKGARMLRGSSLSDIDELAERLFLQHVRDRIYPEMRALVRAHMARGHTVVLSSSALTVQVEPVARYLGIQNVL
SNKFETDDNGCITGEVVRPILWGPGKAHAVQAFAARNGVDLSKSYFYADGDEDVALMYLVGNPRPTNPAGKLAAVAAKRG
WPVLRFSSRSGSSPLSQLRTVAGIGSVLPVAASALGVGLLTRNRRTGVNFFTSTWSRLLLTTAGINLNVLGRENLTAQRP
AVFIFNHRNQADPLIAGRLVETDFTAVGKKELENDPLIGTIGKVMDAAFIDRDDPKAAVEGLRKVEELAGKGLSILIAPE
GTRLDTTEVGEFKKGPFRIAMSARIPIVPIVIRNAEVVAARDSSTFNPGTVDIAVYPPIPTEDWTLQDLPDRIAEIRQIY
LDTLKAWPHGNLPVPALYKRSPGEAVEPRKVEDKPAKKAAKKAAKKTPAKKTPAKKAAKTAEPQPKTSANGRSQPGVKGR
Q

Sequences:

>Translated_561_residues
MSPDDGQQSERRPMRLPGSVAEILAAPEGPQVGAFFDLDGTLVAGFTGVIMTRDRLRRRQMSVGEFIGMVQAGLNHQLGR
SEFEDLIGKGARMLRGSSLSDIDELAERLFLQHVRDRIYPEMRALVRAHMARGHTVVLSSSALTVQVEPVARYLGIQNVL
SNKFETDDNGCITGEVVRPILWGPGKAHAVQAFAARNGVDLSKSYFYADGDEDVALMYLVGNPRPTNPAGKLAAVAAKRG
WPVLRFSSRSGSSPLSQLRTVAGIGSVLPVAASALGVGLLTRNRRTGVNFFTSTWSRLLLTTAGINLNVLGRENLTAQRP
AVFIFNHRNQADPLIAGRLVETDFTAVGKKELENDPLIGTIGKVMDAAFIDRDDPKAAVEGLRKVEELAGKGLSILIAPE
GTRLDTTEVGEFKKGPFRIAMSARIPIVPIVIRNAEVVAARDSSTFNPGTVDIAVYPPIPTEDWTLQDLPDRIAEIRQIY
LDTLKAWPHGNLPVPALYKRSPGEAVEPRKVEDKPAKKAAKKAAKKTPAKKTPAKKAAKTAEPQPKTSANGRSQPGVKGR
Q
>Mature_560_residues
SPDDGQQSERRPMRLPGSVAEILAAPEGPQVGAFFDLDGTLVAGFTGVIMTRDRLRRRQMSVGEFIGMVQAGLNHQLGRS
EFEDLIGKGARMLRGSSLSDIDELAERLFLQHVRDRIYPEMRALVRAHMARGHTVVLSSSALTVQVEPVARYLGIQNVLS
NKFETDDNGCITGEVVRPILWGPGKAHAVQAFAARNGVDLSKSYFYADGDEDVALMYLVGNPRPTNPAGKLAAVAAKRGW
PVLRFSSRSGSSPLSQLRTVAGIGSVLPVAASALGVGLLTRNRRTGVNFFTSTWSRLLLTTAGINLNVLGRENLTAQRPA
VFIFNHRNQADPLIAGRLVETDFTAVGKKELENDPLIGTIGKVMDAAFIDRDDPKAAVEGLRKVEELAGKGLSILIAPEG
TRLDTTEVGEFKKGPFRIAMSARIPIVPIVIRNAEVVAARDSSTFNPGTVDIAVYPPIPTEDWTLQDLPDRIAEIRQIYL
DTLKAWPHGNLPVPALYKRSPGEAVEPRKVEDKPAKKAAKKAAKKTPAKKTPAKKAAKTAEPQPKTSANGRSQPGVKGRQ

Specific function: Converts Lysophosphatidic Acid (Lpa) Into Phosphatidic Acid By Incorporating An Acyl Moiety At The 2 Position. This Enzyme Can Utilize Either Acyl-CoA Or Acyl-Acyl Carrier Protein As The Fatty Acyl Donor. [C]

COG id: COG0560

COG function: function code E; Phosphoserine phosphatase

Gene ontology:

Cell location: Inner Membrane-Associated [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the serB family [H]

Homologues:

Organism=Homo sapiens, GI5453718, Length=183, Percent_Identity=27.8688524590164, Blast_Score=83, Evalue=6e-16,
Organism=Homo sapiens, GI15100175, Length=183, Percent_Identity=27.8688524590164, Blast_Score=83, Evalue=6e-16,
Organism=Homo sapiens, GI6041665, Length=206, Percent_Identity=29.6116504854369, Blast_Score=80, Evalue=3e-15,
Organism=Escherichia coli, GI1789395, Length=160, Percent_Identity=28.125, Blast_Score=65, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17564032, Length=198, Percent_Identity=28.7878787878788, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI17568319, Length=185, Percent_Identity=25.9459459459459, Blast_Score=69, Evalue=4e-12,
Organism=Saccharomyces cerevisiae, GI6320151, Length=185, Percent_Identity=32.4324324324324, Blast_Score=106, Evalue=1e-23,
Organism=Drosophila melanogaster, GI281364648, Length=204, Percent_Identity=29.9019607843137, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24582856, Length=204, Percent_Identity=29.9019607843137, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24582854, Length=204, Percent_Identity=29.9019607843137, Blast_Score=87, Evalue=4e-17,
Organism=Drosophila melanogaster, GI24641614, Length=199, Percent_Identity=28.1407035175879, Blast_Score=86, Evalue=9e-17,
Organism=Drosophila melanogaster, GI24641612, Length=199, Percent_Identity=28.1407035175879, Blast_Score=86, Evalue=9e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006383
- InterPro:   IPR006385 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: 2.3.1.51; 3.1.3.3

Molecular weight: Translated: 60741; Mature: 60609

Theoretical pI: Translated: 10.43; Mature: 10.43

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPDDGQQSERRPMRLPGSVAEILAAPEGPQVGAFFDLDGTLVAGFTGVIMTRDRLRRRQ
CCCCCCCHHCCCCCCCCCHHHHHHCCCCCCCCCEEEECCCEEEHHHHHHHHHHHHHHHHH
MSVGEFIGMVQAGLNHQLGRSEFEDLIGKGARMLRGSSLSDIDELAERLFLQHVRDRIYP
HHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
EMRALVRAHMARGHTVVLSSSALTVQVEPVARYLGIQNVLSNKFETDDNGCITGEVVRPI
HHHHHHHHHHHCCCEEEEECCEEEEEEHHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHH
LWGPGKAHAVQAFAARNGVDLSKSYFYADGDEDVALMYLVGNPRPTNPAGKLAAVAAKRG
HCCCCHHHHHHHHHHCCCCCCCCCEEEECCCCCEEEEEEECCCCCCCCCHHHHHHHHHCC
WPVLRFSSRSGSSPLSQLRTVAGIGSVLPVAASALGVGLLTRNRRTGVNFFTSTWSRLLL
CEEEEECCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
TTAGINLNVLGRENLTAQRPAVFIFNHRNQADPLIAGRLVETDFTAVGKKELENDPLIGT
HHCCCEEEEECCCCCCCCCCEEEEECCCCCCCCHHCCEEECCCHHHHCHHHCCCCCCEEH
IGKVMDAAFIDRDDPKAAVEGLRKVEELAGKGLSILIAPEGTRLDTTEVGEFKKGPFRIA
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHCCCCCCCCEEEE
MSARIPIVPIVIRNAEVVAARDSSTFNPGTVDIAVYPPIPTEDWTLQDLPDRIAEIRQIY
EECCCCEEEEEEECCEEEEECCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHH
LDTLKAWPHGNLPVPALYKRSPGEAVEPRKVEDKPAKKAAKKAAKKTPAKKTPAKKAAKT
HHHHHCCCCCCCCCCHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHC
AEPQPKTSANGRSQPGVKGRQ
CCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SPDDGQQSERRPMRLPGSVAEILAAPEGPQVGAFFDLDGTLVAGFTGVIMTRDRLRRRQ
CCCCCCHHCCCCCCCCCHHHHHHCCCCCCCCCEEEECCCEEEHHHHHHHHHHHHHHHHH
MSVGEFIGMVQAGLNHQLGRSEFEDLIGKGARMLRGSSLSDIDELAERLFLQHVRDRIYP
HHHHHHHHHHHHHCCCCCCHHHHHHHHHCCHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
EMRALVRAHMARGHTVVLSSSALTVQVEPVARYLGIQNVLSNKFETDDNGCITGEVVRPI
HHHHHHHHHHHCCCEEEEECCEEEEEEHHHHHHHHHHHHHCCCCCCCCCCEEEHHHHHHH
LWGPGKAHAVQAFAARNGVDLSKSYFYADGDEDVALMYLVGNPRPTNPAGKLAAVAAKRG
HCCCCHHHHHHHHHHCCCCCCCCCEEEECCCCCEEEEEEECCCCCCCCCHHHHHHHHHCC
WPVLRFSSRSGSSPLSQLRTVAGIGSVLPVAASALGVGLLTRNRRTGVNFFTSTWSRLLL
CEEEEECCCCCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHH
TTAGINLNVLGRENLTAQRPAVFIFNHRNQADPLIAGRLVETDFTAVGKKELENDPLIGT
HHCCCEEEEECCCCCCCCCCEEEEECCCCCCCCHHCCEEECCCHHHHCHHHCCCCCCEEH
IGKVMDAAFIDRDDPKAAVEGLRKVEELAGKGLSILIAPEGTRLDTTEVGEFKKGPFRIA
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCHHCCCCCCCCEEEE
MSARIPIVPIVIRNAEVVAARDSSTFNPGTVDIAVYPPIPTEDWTLQDLPDRIAEIRQIY
EECCCCEEEEEEECCEEEEECCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHH
LDTLKAWPHGNLPVPALYKRSPGEAVEPRKVEDKPAKKAAKKAAKKTPAKKTPAKKAAKT
HHHHHCCCCCCCCCCHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCHHHHHHC
AEPQPKTSANGRSQPGVKGRQ
CCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA; 1-acyl-sn-glycerol 3-phosphate

Specific reaction: acyl-CoA + 1-acyl-sn-glycerol 3-phosphate = CoA + 1,2-diacyl-sn-glycerol 3-phosphate

General reaction: Acyl group transfer [C]

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9634230; 12218036 [H]