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The map label for this gene is prcB

Identifier: 108800096

GI number: 108800096

Start: 3322016

End: 3322930

Strand: Reverse

Name: prcB

Synonym: Mmcs_3130

Alternate gene names: 108800096

Gene position: 3322930-3322016 (Counterclockwise)

Preceding gene: 108800097

Following gene: 108800095

Centisome position: 58.24

GC content: 67.98

Gene sequence:

>915_bases
GTGACCTGGCCGCACTTCGAGCAGCTGGCCTTTCCTGACCTTTCCCGACATTCGTCCCACTCCACGACCCGAGGGGTTCC
CTCCGTACCCATGGACTTGTCGTCCTTCTCCGACATGCTGCGCCGTCAGGCGCCCCACCTGTTGCCGTTCCGCGGCGACG
CCTCGCTGACCCCCACCGACGCGGTGCCGCACGGCACCACGATCGTCGCGCTGAAGTTCCCCGGCGGCGTGGTGATGGCC
GGTGACCGGCGCGCCACCCAGGGCAACATGATCGCCAGCCGCGACGTGCAGAAGGTCTACATCACCGACGACTACACGGC
GACCGGCATCGCGGGCACCGCCGCCATCGCGGTGGAGTTCGCCCGCCTGTACGCGGTGGAACTCGAACACTACGAGAAGC
TCGAAGGCGTCGCGCTGACGTTCGCGGGCAAGGTCAACCGGCTCGCCACCATGGTGCGCGGCAATCTCGGTGCGGCGCTG
CAGGGTTTCGTGGCCCTGCCGCTGCTGGCCGGCTTCGACCTCGACGACCCCGACCCGCAGGCCGCCGGGCGCATCGTGTC
GTTCGACGCCGCGGGTGGACACAATCTCGAAGAAGAGGGTTTCCAGTCGGTCGGATCGGGCTCCATCTTCGCCAAGTCGT
CGATGAAGAAGCTCTACCACCAGGTGACCGATGCCGACTCGGCGCTGCGGGTGGCGGTCGAGGCGCTCTACGACGCCGCC
GATGACGATTCGGCCACCGGCGGACCGGATCTGGTGCGCGGCATCTTCCCGACCGCGGTGCTGATCACCGCCGACGGGGC
CGAAGAGGTCACCCAGGAGCGGATCGCCGGACTGGCCCGCGAAGTCATTCAAAACCGTTCCCGCGCCGACACTTTCGGCC
CTGACGCGCATGCGCCGCGAGGTACAGATTCGTGA

Upstream 100 bases:

>100_bases
AGCTCGCCGAGGAGACCGACGACCTGCTGGACGAGATCGACGACGTCCTCGAGGAGAACGCCGAGGACTTCGTGCGCGCT
TACGTCCAAAAGGGCGGACA

Downstream 100 bases:

>100_bases
GTTTCCCGTATTTCATCTCGCCCGAGCAGGCGATGCGCGAGCGTTCCGAGCTCGCCCGCAAGGGAATCGCCAGGGGCCGC
AGCGTGGTCGCGCTGGCCTA

Product: proteasome subunit beta

Products: NA

Alternate protein names: 20S proteasome beta subunit; Proteasome core protein PrcB

Number of amino acids: Translated: 304; Mature: 303

Protein sequence:

>304_residues
MTWPHFEQLAFPDLSRHSSHSTTRGVPSVPMDLSSFSDMLRRQAPHLLPFRGDASLTPTDAVPHGTTIVALKFPGGVVMA
GDRRATQGNMIASRDVQKVYITDDYTATGIAGTAAIAVEFARLYAVELEHYEKLEGVALTFAGKVNRLATMVRGNLGAAL
QGFVALPLLAGFDLDDPDPQAAGRIVSFDAAGGHNLEEEGFQSVGSGSIFAKSSMKKLYHQVTDADSALRVAVEALYDAA
DDDSATGGPDLVRGIFPTAVLITADGAEEVTQERIAGLAREVIQNRSRADTFGPDAHAPRGTDS

Sequences:

>Translated_304_residues
MTWPHFEQLAFPDLSRHSSHSTTRGVPSVPMDLSSFSDMLRRQAPHLLPFRGDASLTPTDAVPHGTTIVALKFPGGVVMA
GDRRATQGNMIASRDVQKVYITDDYTATGIAGTAAIAVEFARLYAVELEHYEKLEGVALTFAGKVNRLATMVRGNLGAAL
QGFVALPLLAGFDLDDPDPQAAGRIVSFDAAGGHNLEEEGFQSVGSGSIFAKSSMKKLYHQVTDADSALRVAVEALYDAA
DDDSATGGPDLVRGIFPTAVLITADGAEEVTQERIAGLAREVIQNRSRADTFGPDAHAPRGTDS
>Mature_303_residues
TWPHFEQLAFPDLSRHSSHSTTRGVPSVPMDLSSFSDMLRRQAPHLLPFRGDASLTPTDAVPHGTTIVALKFPGGVVMAG
DRRATQGNMIASRDVQKVYITDDYTATGIAGTAAIAVEFARLYAVELEHYEKLEGVALTFAGKVNRLATMVRGNLGAALQ
GFVALPLLAGFDLDDPDPQAAGRIVSFDAAGGHNLEEEGFQSVGSGSIFAKSSMKKLYHQVTDADSALRVAVEALYDAAD
DDSATGGPDLVRGIFPTAVLITADGAEEVTQERIAGLAREVIQNRSRADTFGPDAHAPRGTDS

Specific function: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation

COG id: COG0638

COG function: function code O; 20S proteasome, alpha and beta subunits

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase T1B family

Homologues:

Organism=Homo sapiens, GI4506201, Length=191, Percent_Identity=31.9371727748691, Blast_Score=75, Evalue=8e-14,
Organism=Saccharomyces cerevisiae, GI6325360, Length=187, Percent_Identity=27.2727272727273, Blast_Score=63, Evalue=7e-11,
Organism=Drosophila melanogaster, GI20130281, Length=190, Percent_Identity=31.5789473684211, Blast_Score=71, Evalue=8e-13,
Organism=Drosophila melanogaster, GI21355573, Length=191, Percent_Identity=28.2722513089005, Blast_Score=66, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24652553, Length=191, Percent_Identity=28.2722513089005, Blast_Score=66, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PSB_MYCSJ (A3Q193)

Other databases:

- EMBL:   CP000580
- RefSeq:   YP_001071411.1
- ProteinModelPortal:   A3Q193
- SMR:   A3Q193
- MEROPS:   T01.005
- EnsemblBacteria:   EBMYCT00000052616
- GeneID:   4878854
- GenomeReviews:   CP000580_GR
- KEGG:   mjl:Mjls_3141
- eggNOG:   COG0638
- GeneTree:   EBGT00050000016799
- HOGENOM:   HBG322409
- OMA:   FQVELEH
- PhylomeDB:   A3Q193
- ProtClustDB:   CLSK872008
- GO:   GO:0005737
- HAMAP:   MF_02113_B
- InterPro:   IPR022483
- InterPro:   IPR001353
- TIGRFAMs:   TIGR03690

Pfam domain/function: PF00227 Proteasome

EC number: =3.4.25.1

Molecular weight: Translated: 32266; Mature: 32135

Theoretical pI: Translated: 4.90; Mature: 4.90

Prosite motif: PS00854 PROTEASOME_B_1; PS51476 PROTEASOME_B_2

Important sites: ACT_SITE 66-66

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTWPHFEQLAFPDLSRHSSHSTTRGVPSVPMDLSSFSDMLRRQAPHLLPFRGDASLTPTD
CCCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEECCCCCCCCCC
AVPHGTTIVALKFPGGVVMAGDRRATQGNMIASRDVQKVYITDDYTATGIAGTAAIAVEF
CCCCCCEEEEEECCCCEEEECCCCCCCCCEEECCCCEEEEEECCCCCCCCCHHHHHHHHH
ARLYAVELEHYEKLEGVALTFAGKVNRLATMVRGNLGAALQGFVALPLLAGFDLDDPDPQ
HHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCHH
AAGRIVSFDAAGGHNLEEEGFQSVGSGSIFAKSSMKKLYHQVTDADSALRVAVEALYDAA
HCCCEEEEECCCCCCCCHHHHHHCCCCCEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHCC
DDDSATGGPDLVRGIFPTAVLITADGAEEVTQERIAGLAREVIQNRSRADTFGPDAHAPR
CCCCCCCCHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
GTDS
CCCC
>Mature Secondary Structure 
TWPHFEQLAFPDLSRHSSHSTTRGVPSVPMDLSSFSDMLRRQAPHLLPFRGDASLTPTD
CCCCCHHHCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCCEECCCCCCCCCC
AVPHGTTIVALKFPGGVVMAGDRRATQGNMIASRDVQKVYITDDYTATGIAGTAAIAVEF
CCCCCCEEEEEECCCCEEEECCCCCCCCCEEECCCCEEEEEECCCCCCCCCHHHHHHHHH
ARLYAVELEHYEKLEGVALTFAGKVNRLATMVRGNLGAALQGFVALPLLAGFDLDDPDPQ
HHHHHHHHHHHHHHCCEEEEEHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCHH
AAGRIVSFDAAGGHNLEEEGFQSVGSGSIFAKSSMKKLYHQVTDADSALRVAVEALYDAA
HCCCEEEEECCCCCCCCHHHHHHCCCCCEEHHHHHHHHHHHHHCCHHHHHHHHHHHHHCC
DDDSATGGPDLVRGIFPTAVLITADGAEEVTQERIAGLAREVIQNRSRADTFGPDAHAPR
CCCCCCCCHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCC
GTDS
CCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA