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The map label for this gene is prcA

Identifier: 108800095

GI number: 108800095

Start: 3321267

End: 3322019

Strand: Reverse

Name: prcA

Synonym: Mmcs_3129

Alternate gene names: 108800095

Gene position: 3322019-3321267 (Counterclockwise)

Preceding gene: 108800096

Following gene: 108800093

Centisome position: 58.23

GC content: 67.6

Gene sequence:

>753_bases
GTGAGTTTCCCGTATTTCATCTCGCCCGAGCAGGCGATGCGCGAGCGTTCCGAGCTCGCCCGCAAGGGAATCGCCAGGGG
CCGCAGCGTGGTCGCGCTGGCCTACGCCGACGGGGTCCTGTTCGTCGCGGAGAACCCGTCGCGGTCACTTCAGAAGGTCA
GTGAACTGTACGACCGCGTCGGCTTCGCCGCGGTCGGGCGCTTCAACGAGTTCAACAACTTGCGCAGCGGCGGTATCCGG
TTCGCCGACACCCAGGGGTATGCGTATTCGCGCCGCGACGTGACCGGCCGACAGCTGGCCAATGTCTACGCGCAGACGCT
CGGCACGATCTTCACCGAACAGGCCAAACCCTACGAGGTGGAGCTGTGTGTGGCCGAGGTCGCGCACTTCGGCGAGTCCA
AAGCGCCGGAGCTCTACCGGATCACCTACGACGGGTCGATCGCCGACGAACCCCACTTCGTGGTGATGGGCGGCGCCACC
GAGCCGATCATCGCCAAACTCAACGACTCCTACACCGAGAACGCCGAACTCGCCGACGCGGTGCGTATCGCGGTCGACGC
CCTCGAGTCCGGCGGTAACGGGGCCGAGCGACGCACGCTCGGCCCGTCGACTCTGGAAGTGGCGATCCTGGACGCCAACC
GGCCCCGGCGGGCGTTTCGCCGGATCACCGGATCCGCACTCGAAGCGCTTCTGCCGCAGCGGGATGCGGAGGCGTCGGCG
GATGCCGGCGCGGCGGACAAGCCCGCCGAGTAA

Upstream 100 bases:

>100_bases
CCCAGGAGCGGATCGCCGGACTGGCCCGCGAAGTCATTCAAAACCGTTCCCGCGCCGACACTTTCGGCCCTGACGCGCAT
GCGCCGCGAGGTACAGATTC

Downstream 100 bases:

>100_bases
CCGGCGTCAGCGCCGCCAGGCGGAGTGCAGGATCGCGGTGAGCGCGGCGATCCGCGCCGTCCGCACCACACCCACCAGGG
GGCGCAGCGCATCGCTGGCG

Product: 20S proteasome, A and B subunits

Products: NA

Alternate protein names: 20S proteasome alpha subunit; Proteasome core protein PrcA

Number of amino acids: Translated: 250; Mature: 249

Protein sequence:

>250_residues
MSFPYFISPEQAMRERSELARKGIARGRSVVALAYADGVLFVAENPSRSLQKVSELYDRVGFAAVGRFNEFNNLRSGGIR
FADTQGYAYSRRDVTGRQLANVYAQTLGTIFTEQAKPYEVELCVAEVAHFGESKAPELYRITYDGSIADEPHFVVMGGAT
EPIIAKLNDSYTENAELADAVRIAVDALESGGNGAERRTLGPSTLEVAILDANRPRRAFRRITGSALEALLPQRDAEASA
DAGAADKPAE

Sequences:

>Translated_250_residues
MSFPYFISPEQAMRERSELARKGIARGRSVVALAYADGVLFVAENPSRSLQKVSELYDRVGFAAVGRFNEFNNLRSGGIR
FADTQGYAYSRRDVTGRQLANVYAQTLGTIFTEQAKPYEVELCVAEVAHFGESKAPELYRITYDGSIADEPHFVVMGGAT
EPIIAKLNDSYTENAELADAVRIAVDALESGGNGAERRTLGPSTLEVAILDANRPRRAFRRITGSALEALLPQRDAEASA
DAGAADKPAE
>Mature_249_residues
SFPYFISPEQAMRERSELARKGIARGRSVVALAYADGVLFVAENPSRSLQKVSELYDRVGFAAVGRFNEFNNLRSGGIRF
ADTQGYAYSRRDVTGRQLANVYAQTLGTIFTEQAKPYEVELCVAEVAHFGESKAPELYRITYDGSIADEPHFVVMGGATE
PIIAKLNDSYTENAELADAVRIAVDALESGGNGAERRTLGPSTLEVAILDANRPRRAFRRITGSALEALLPQRDAEASAD
AGAADKPAE

Specific function: Component of the proteasome core, a large protease complex with broad specificity involved in protein degradation

COG id: COG0638

COG function: function code O; 20S proteasome, alpha and beta subunits

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase T1A family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): PSA_MYCSJ (A3Q192)

Other databases:

- EMBL:   CP000580
- RefSeq:   YP_001071410.1
- ProteinModelPortal:   A3Q192
- SMR:   A3Q192
- STRING:   A3Q192
- EnsemblBacteria:   EBMYCT00000048515
- GeneID:   4878853
- GenomeReviews:   CP000580_GR
- KEGG:   mjl:Mjls_3140
- eggNOG:   COG0638
- GeneTree:   EBGT00050000016603
- HOGENOM:   HBG292323
- OMA:   AVGKYNE
- ProtClustDB:   CLSK872007
- BioCyc:   MSP164757:MJLS_3140-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00289_B
- InterPro:   IPR022296
- InterPro:   IPR001353
- TIGRFAMs:   TIGR03691

Pfam domain/function: PF00227 Proteasome

EC number: =3.4.25.1

Molecular weight: Translated: 27158; Mature: 27026

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: PS00388 PROTEASOME_A_1; PS51475 PROTEASOME_A_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFPYFISPEQAMRERSELARKGIARGRSVVALAYADGVLFVAENPSRSLQKVSELYDRV
CCCCCEECHHHHHHHHHHHHHHHHHCCCCEEEEEEECCEEEEECCCHHHHHHHHHHHHHH
GFAAVGRFNEFNNLRSGGIRFADTQGYAYSRRDVTGRQLANVYAQTLGTIFTEQAKPYEV
HHHHHHCHHHHHHHCCCCEEEEECCCCEECCCCCCHHHHHHHHHHHHHHHHHCCCCCEEH
ELCVAEVAHFGESKAPELYRITYDGSIADEPHFVVMGGATEPIIAKLNDSYTENAELADA
HHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCEEEECCCCCCEEEECCCCCCCCHHHHHH
VRIAVDALESGGNGAERRTLGPSTLEVAILDANRPRRAFRRITGSALEALLPQRDAEASA
HHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCC
DAGAADKPAE
CCCCCCCCCC
>Mature Secondary Structure 
SFPYFISPEQAMRERSELARKGIARGRSVVALAYADGVLFVAENPSRSLQKVSELYDRV
CCCCEECHHHHHHHHHHHHHHHHHCCCCEEEEEEECCEEEEECCCHHHHHHHHHHHHHH
GFAAVGRFNEFNNLRSGGIRFADTQGYAYSRRDVTGRQLANVYAQTLGTIFTEQAKPYEV
HHHHHHCHHHHHHHCCCCEEEEECCCCEECCCCCCHHHHHHHHHHHHHHHHHCCCCCEEH
ELCVAEVAHFGESKAPELYRITYDGSIADEPHFVVMGGATEPIIAKLNDSYTENAELADA
HHHHHHHHHCCCCCCCCEEEEEECCCCCCCCCEEEECCCCCCEEEECCCCCCCCHHHHHH
VRIAVDALESGGNGAERRTLGPSTLEVAILDANRPRRAFRRITGSALEALLPQRDAEASA
HHHHHHHHHCCCCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCCCCCC
DAGAADKPAE
CCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA