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The map label for this gene is hisC [H]

Identifier: 108800028

GI number: 108800028

Start: 3237361

End: 3238494

Strand: Reverse

Name: hisC [H]

Synonym: Mmcs_3062

Alternate gene names: 108800028

Gene position: 3238494-3237361 (Counterclockwise)

Preceding gene: 108800029

Following gene: 108800027

Centisome position: 56.76

GC content: 68.34

Gene sequence:

>1134_bases
ATGACCGTGGGGGAGCGGATCACCCTCGCCGACCTGCCCCTGCGGGATGACCTGCGCGGAAAGTCACCCTACGGTGCACC
GCAACTGCAGGTGCCGGTGCGGCTGAACACCAACGAGAACCCGCATCCGCCCAGTCAGGCACTCGTCGACGACGTGACCC
GATCGGTCGGGGAGGCGGCCGCCGAACTGCACCGCTATCCCGACCGTGACGCGGTGGCGCTGCGCAGCGACCTGGCCGAC
TATCTGAACCTGCGCACCGGTGTCGAGCTGAGCGTCGAGAACCTCTGGGCCGCAAACGGTTCCAACGAGGTCCTGCAACA
GCTTCTGCAGGCCTTCGGCGGCCCAGGGCGCAGCGCGATCGGCTTCGTGCCCTCGTACTCGATGCACCCGATCATCGCCG
ACGCCACCCGAACCGAATGGCTGCAGGCGCTGCGCGCCGACGACTTCGGACTCGATGTCGACACCGCCGTGCGCGAGATC
GCCGCCCGCCGTCCCGATCTGGTGTTCGTGACCAGCCCCAACAACCCGTCGGGACAGAGCGTCCCGCTCGAGGACCTGCG
GCGGTTGCTCGACGCCATGGAGACCGGAATCCTGATCCTCGACGAGGCCTACGGTGAATTCTCCTCCCAGCCCAGCGGTG
TGGCGCTCATCGACCAGTACCCGACCAAGCTGGTCGTCAGCCGCACCATGAGCAAGGCGTTCGCGTTCGCCGGCGGGCGC
CTCGGCTACCTGGTGGCCGCACCCGCCGTCATCGAGGCGATGCTGCTGGTGCGGTTGCCCTACCACCTGTCCTCGCTGAC
CCAGGCCGCCGCCCGGGCGGCGCTTCGGCACGCCGACGACACGCTGGCCAGCGTCGCCACCCTGATCGCCGAACGGGACC
GGGTCGCAAACGGCTTGAGCCAGCTCGGGTTCCGGGTGGTGCCCAGCGACGCGAACTTCATCCTGTTCGGGGAGTTCGCC
GATGCCCCGGCCACCTGGCGGCGCTACCTCGATCAGGGGGTGCTCATCCGGGACGTGGGCATACCCGGCTACCTGCGGAC
CACAATCGGGTTGGCCGAAGAGAACGATGCGCTGCTGACCGCCTCAGCCCGCCTCGTCGAGACCGAACTCGCGGCAACAT
TAGGAGCCTTATGA

Upstream 100 bases:

>100_bases
CCGAGGCGGCGCTCAAGGACGTGTCGGGATACGTGATCACCCTGGCGCAGGCCGAGAACCTGCCCGCCCACGGCGAAGCG
GTGCGACGGAGGTTCGAGTC

Downstream 100 bases:

>100_bases
CCGACATGCTGACCGGCACCCGCCGCGCCCGCGTCGAACGCAAGACCAAGGAATCGGACATCGTCGTCGATCTCGACCTC
GACGGCACCGGCATCGTCGA

Product: histidinol-phosphate aminotransferase

Products: NA

Alternate protein names: Imidazole acetol-phosphate transaminase [H]

Number of amino acids: Translated: 377; Mature: 376

Protein sequence:

>377_residues
MTVGERITLADLPLRDDLRGKSPYGAPQLQVPVRLNTNENPHPPSQALVDDVTRSVGEAAAELHRYPDRDAVALRSDLAD
YLNLRTGVELSVENLWAANGSNEVLQQLLQAFGGPGRSAIGFVPSYSMHPIIADATRTEWLQALRADDFGLDVDTAVREI
AARRPDLVFVTSPNNPSGQSVPLEDLRRLLDAMETGILILDEAYGEFSSQPSGVALIDQYPTKLVVSRTMSKAFAFAGGR
LGYLVAAPAVIEAMLLVRLPYHLSSLTQAAARAALRHADDTLASVATLIAERDRVANGLSQLGFRVVPSDANFILFGEFA
DAPATWRRYLDQGVLIRDVGIPGYLRTTIGLAEENDALLTASARLVETELAATLGAL

Sequences:

>Translated_377_residues
MTVGERITLADLPLRDDLRGKSPYGAPQLQVPVRLNTNENPHPPSQALVDDVTRSVGEAAAELHRYPDRDAVALRSDLAD
YLNLRTGVELSVENLWAANGSNEVLQQLLQAFGGPGRSAIGFVPSYSMHPIIADATRTEWLQALRADDFGLDVDTAVREI
AARRPDLVFVTSPNNPSGQSVPLEDLRRLLDAMETGILILDEAYGEFSSQPSGVALIDQYPTKLVVSRTMSKAFAFAGGR
LGYLVAAPAVIEAMLLVRLPYHLSSLTQAAARAALRHADDTLASVATLIAERDRVANGLSQLGFRVVPSDANFILFGEFA
DAPATWRRYLDQGVLIRDVGIPGYLRTTIGLAEENDALLTASARLVETELAATLGAL
>Mature_376_residues
TVGERITLADLPLRDDLRGKSPYGAPQLQVPVRLNTNENPHPPSQALVDDVTRSVGEAAAELHRYPDRDAVALRSDLADY
LNLRTGVELSVENLWAANGSNEVLQQLLQAFGGPGRSAIGFVPSYSMHPIIADATRTEWLQALRADDFGLDVDTAVREIA
ARRPDLVFVTSPNNPSGQSVPLEDLRRLLDAMETGILILDEAYGEFSSQPSGVALIDQYPTKLVVSRTMSKAFAFAGGRL
GYLVAAPAVIEAMLLVRLPYHLSSLTQAAARAALRHADDTLASVATLIAERDRVANGLSQLGFRVVPSDANFILFGEFAD
APATWRRYLDQGVLIRDVGIPGYLRTTIGLAEENDALLTASARLVETELAATLGAL

Specific function: Histidine biosynthesis; seventh step. [C]

COG id: COG0079

COG function: function code E; Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788332, Length=374, Percent_Identity=30.7486631016043, Blast_Score=142, Evalue=5e-35,
Organism=Saccharomyces cerevisiae, GI6322075, Length=354, Percent_Identity=29.6610169491525, Blast_Score=129, Evalue=8e-31,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001917
- InterPro:   IPR004839
- InterPro:   IPR005861
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: =2.6.1.9 [H]

Molecular weight: Translated: 40679; Mature: 40547

Theoretical pI: Translated: 4.62; Mature: 4.62

Prosite motif: PS00599 AA_TRANSFER_CLASS_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTVGERITLADLPLRDDLRGKSPYGAPQLQVPVRLNTNENPHPPSQALVDDVTRSVGEAA
CCCCCEEEEECCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHH
AELHRYPDRDAVALRSDLADYLNLRTGVELSVENLWAANGSNEVLQQLLQAFGGPGRSAI
HHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEHHHHCCCCCCHHHHHHHHHHHCCCCCCCE
GFVPSYSMHPIIADATRTEWLQALRADDFGLDVDTAVREIAARRPDLVFVTSPNNPSGQS
ECCCCCCCCCEEECHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCC
VPLEDLRRLLDAMETGILILDEAYGEFSSQPSGVALIDQYPTKLVVSRTMSKAFAFAGGR
CCHHHHHHHHHHHHCCEEEEECCHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHHCCCC
LGYLVAAPAVIEAMLLVRLPYHLSSLTQAAARAALRHADDTLASVATLIAERDRVANGLS
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLGFRVVPSDANFILFGEFADAPATWRRYLDQGVLIRDVGIPGYLRTTIGLAEENDALLT
HCCCEEECCCCCEEEEECCCCCCHHHHHHHHCCCEEEECCCCCHHHHHHCCCCCCCCEEE
ASARLVETELAATLGAL
HHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TVGERITLADLPLRDDLRGKSPYGAPQLQVPVRLNTNENPHPPSQALVDDVTRSVGEAA
CCCCEEEEECCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHH
AELHRYPDRDAVALRSDLADYLNLRTGVELSVENLWAANGSNEVLQQLLQAFGGPGRSAI
HHHHCCCCCHHHHHHHHHHHHHHHCCCCEEEHHHHCCCCCCHHHHHHHHHHHCCCCCCCE
GFVPSYSMHPIIADATRTEWLQALRADDFGLDVDTAVREIAARRPDLVFVTSPNNPSGQS
ECCCCCCCCCEEECHHHHHHHHHHHCCCCCCCHHHHHHHHHHCCCCEEEEECCCCCCCCC
VPLEDLRRLLDAMETGILILDEAYGEFSSQPSGVALIDQYPTKLVVSRTMSKAFAFAGGR
CCHHHHHHHHHHHHCCEEEEECCHHHCCCCCCCEEEECCCCHHHHHHHHHHHHHHHCCCC
LGYLVAAPAVIEAMLLVRLPYHLSSLTQAAARAALRHADDTLASVATLIAERDRVANGLS
HHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QLGFRVVPSDANFILFGEFADAPATWRRYLDQGVLIRDVGIPGYLRTTIGLAEENDALLT
HCCCEEECCCCCEEEEECCCCCCHHHHHHHHCCCEEEECCCCCHHHHHHCCCCCCCCEEE
ASARLVETELAATLGAL
HHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA