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The map label for this gene is tesB [H]

Identifier: 108800007

GI number: 108800007

Start: 3213103

End: 3213966

Strand: Reverse

Name: tesB [H]

Synonym: Mmcs_3041

Alternate gene names: 108800007

Gene position: 3213966-3213103 (Counterclockwise)

Preceding gene: 108800008

Following gene: 108800000

Centisome position: 56.33

GC content: 68.63

Gene sequence:

>864_bases
TTGTCGGCAGCGGATTTCGACGAGCTGCTGGCACTGCTCGACCTCCGCAGGGTCGACGACGACACCTTCGCCGGATCGCA
CCCGAGCAAGAACCCGGTCCGCACCTTCGGCGGCCAGATGATGGCGCAGGCGTTCGTGGCGGCCAGTCGTGCGGTCGACC
ACCGGATCTCGCCCAGCGCGCTGTCGGTGCATTTCGTCGCCGGCGGCGACCCGGCCCGCGAGCTCGAGTTCCGGGTGACG
CGGTTGCGCGACGAACGGCGGTTCGCCAACCGCCGGGTCGACGTGTGCCAGGGCCAGGACCTGTTGGCCACCGCGATGGT
GTCGTACATGAACGGCGGGCGCGGCCTCGAACACGGAGTCGCGGCCCCCGATGTCCCGGGGCCCGAGGAGCTGCCGAAGA
TCGGCGAGTTGCTGCGCGGTTACGAGGAGACAGTGCCGCACTTCGTGAACGCGTTGCGGCCGATCGAGTGGCGCTACACC
AACGATCCGGCCTGGGTGATGCGCGACAAAGGACAGCGCCTCGACCACAACCGGGTGTGGCTCAAGACCGAAGGCGCGAT
GCCCGACGACCCGGTGCTGCACACCGCGGCGCTGGTCTACTCGTCGGACACCACGGTGCTGGACTCGATCATCACCACCC
ACGGCCTGTCGTGGGGATTCGACCGCATCTTCGCTGCGACGATGAACCATTCGGTGTGGTTCCACCGACCGGTGCGGTTC
GACGAGTGGGTGCTGTACTCGACCTCCTCGCCCGTGGCCGCCGAGTCACGCGGCCTCGGCACCGGGCACTTCTTCGACCG
GTCCGGCGCGCTGCTGGCGACAGTCGCGTCGGACGCGGTCGTGAAGTACTTCCCGGGCCGCTAA

Upstream 100 bases:

>100_bases
GTCATCGTCGCGGGTGCGCCGCCGGGCACAGTAGGCTCCACGAATCTGATCCACGTGCACCGGATCGGGGAGGACGACGT
CTAGATCCTGAGGGGGCATC

Downstream 100 bases:

>100_bases
CGCGAGGGCGTCACCGTGACGCTGAACTGGTCTTCGATGTTGCGCTCGAACTGCTCCTGGCACTCCTGCTGCGCGGCGGC
GTCGTTACCGGCCTCCTGCA

Product: acyl-CoA thioesterase

Products: Hydrolyzed acyl-CoA thioesters [C]

Alternate protein names: Acyl-CoA thioesterase II; TEII [H]

Number of amino acids: Translated: 287; Mature: 286

Protein sequence:

>287_residues
MSAADFDELLALLDLRRVDDDTFAGSHPSKNPVRTFGGQMMAQAFVAASRAVDHRISPSALSVHFVAGGDPARELEFRVT
RLRDERRFANRRVDVCQGQDLLATAMVSYMNGGRGLEHGVAAPDVPGPEELPKIGELLRGYEETVPHFVNALRPIEWRYT
NDPAWVMRDKGQRLDHNRVWLKTEGAMPDDPVLHTAALVYSSDTTVLDSIITTHGLSWGFDRIFAATMNHSVWFHRPVRF
DEWVLYSTSSPVAAESRGLGTGHFFDRSGALLATVASDAVVKYFPGR

Sequences:

>Translated_287_residues
MSAADFDELLALLDLRRVDDDTFAGSHPSKNPVRTFGGQMMAQAFVAASRAVDHRISPSALSVHFVAGGDPARELEFRVT
RLRDERRFANRRVDVCQGQDLLATAMVSYMNGGRGLEHGVAAPDVPGPEELPKIGELLRGYEETVPHFVNALRPIEWRYT
NDPAWVMRDKGQRLDHNRVWLKTEGAMPDDPVLHTAALVYSSDTTVLDSIITTHGLSWGFDRIFAATMNHSVWFHRPVRF
DEWVLYSTSSPVAAESRGLGTGHFFDRSGALLATVASDAVVKYFPGR
>Mature_286_residues
SAADFDELLALLDLRRVDDDTFAGSHPSKNPVRTFGGQMMAQAFVAASRAVDHRISPSALSVHFVAGGDPARELEFRVTR
LRDERRFANRRVDVCQGQDLLATAMVSYMNGGRGLEHGVAAPDVPGPEELPKIGELLRGYEETVPHFVNALRPIEWRYTN
DPAWVMRDKGQRLDHNRVWLKTEGAMPDDPVLHTAALVYSSDTTVLDSIITTHGLSWGFDRIFAATMNHSVWFHRPVRFD
EWVLYSTSSPVAAESRGLGTGHFFDRSGALLATVASDAVVKYFPGR

Specific function: Can hydrolyze a broad range of acyl-CoA thioesters. Its physiological function is not known [H]

COG id: COG1946

COG function: function code I; Acyl-CoA thioesterase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the C/M/P thioester hydrolase family [H]

Homologues:

Organism=Homo sapiens, GI34577075, Length=287, Percent_Identity=29.9651567944251, Blast_Score=129, Evalue=3e-30,
Organism=Escherichia coli, GI1786657, Length=274, Percent_Identity=29.1970802919708, Blast_Score=132, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI17558508, Length=310, Percent_Identity=27.4193548387097, Blast_Score=116, Evalue=1e-26,
Organism=Caenorhabditis elegans, GI71988741, Length=293, Percent_Identity=25.2559726962457, Blast_Score=107, Evalue=5e-24,
Organism=Caenorhabditis elegans, GI115532456, Length=307, Percent_Identity=26.0586319218241, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17531889, Length=307, Percent_Identity=26.0586319218241, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17531885, Length=307, Percent_Identity=26.0586319218241, Blast_Score=106, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI71982224, Length=299, Percent_Identity=25.752508361204, Blast_Score=95, Evalue=4e-20,
Organism=Caenorhabditis elegans, GI212645202, Length=291, Percent_Identity=26.1168384879725, Blast_Score=84, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003703 [H]

Pfam domain/function: PF02551 Acyl_CoA_thio [H]

EC number: 3.1.2.- [C]

Molecular weight: Translated: 31878; Mature: 31747

Theoretical pI: Translated: 6.44; Mature: 6.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAADFDELLALLDLRRVDDDTFAGSHPSKNPVRTFGGQMMAQAFVAASRAVDHRISPSA
CCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
LSVHFVAGGDPARELEFRVTRLRDERRFANRRVDVCQGQDLLATAMVSYMNGGRGLEHGV
EEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCC
AAPDVPGPEELPKIGELLRGYEETVPHFVNALRPIEWRYTNDPAWVMRDKGQRLDHNRVW
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEECCCCCCCCCCEEE
LKTEGAMPDDPVLHTAALVYSSDTTVLDSIITTHGLSWGFDRIFAATMNHSVWFHRPVRF
EEECCCCCCCCHHHHEEEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEECCCCC
DEWVLYSTSSPVAAESRGLGTGHFFDRSGALLATVASDAVVKYFPGR
CCEEEEECCCCCCHHCCCCCCCCEECCCCCEEEEECCCCCEECCCCC
>Mature Secondary Structure 
SAADFDELLALLDLRRVDDDTFAGSHPSKNPVRTFGGQMMAQAFVAASRAVDHRISPSA
CCCCHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
LSVHFVAGGDPARELEFRVTRLRDERRFANRRVDVCQGQDLLATAMVSYMNGGRGLEHGV
EEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHCCCCCCCCCC
AAPDVPGPEELPKIGELLRGYEETVPHFVNALRPIEWRYTNDPAWVMRDKGQRLDHNRVW
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEECCCCCEEECCCCCCCCCCEEE
LKTEGAMPDDPVLHTAALVYSSDTTVLDSIITTHGLSWGFDRIFAATMNHSVWFHRPVRF
EEECCCCCCCCHHHHEEEEECCCHHHHHHHHHHCCCCCCHHHHHHHHHCCCEEEECCCCC
DEWVLYSTSSPVAAESRGLGTGHFFDRSGALLATVASDAVVKYFPGR
CCEEEEECCCCCCHHCCCCCCCCEECCCCCEEEEECCCCCEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: acyl-CoA thioesters [C]

Specific reaction: Hydrolyzes a broad range of acyl-CoA thioesters [C]

General reaction: Hydrolase; Acting on ester bonds; Thiolester hydrolases [C]

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]