Click here to switch to the map view.

The map label for this gene is add [H]

Identifier: 108798204

GI number: 108798204

Start: 1331463

End: 1332551

Strand: Direct

Name: add [H]

Synonym: Mmcs_1233

Alternate gene names: 108798204

Gene position: 1331463-1332551 (Clockwise)

Preceding gene: 108798203

Following gene: 108798207

Centisome position: 23.34

GC content: 68.69

Gene sequence:

>1089_bases
ATGACGACACCGCTGACGCTGGAGAACATCAGCCAGGCGCCCAAGGCGCTGCTGCACGATCACCTCGACGGCGGTCTGCG
CCCGTCGACGGTCCTCGAACTGGCCGGACAGTACGGCTACGACGATCTGCCCGCCGACGACGTCGACGAGCTGGCGACGT
TCTTCCGCACCGCCGCCCACAGCGGGTCGCTGGTGCGCTACCTCGAACCGTTCGCCCACACCGTCGGGGTGATGCAGACC
GCCGAAGCGCTGCACCGGGTGGCGTTCGAATGCGTCGAGGATCTCGCCGGCGACAACGTCGTCTACGCCGAGGTGCGGTT
CGCCCCGGAACTGCACATCGAGGGTGGGATGGGCCTGGACGCGGTCGTCGACGCCGTGCTCGCCGGTTTCGCCGACGGGG
AGAAGGCCGCCGCCAGCGCGGGTCGCACGATCACTGTCCGCTGCCTGGTGACCGCGATGCGCCACGCCGCGCGCTCACGC
GAGATCGCCGAACTGGCCATCCGATTCCGCGACCGCGGCGTCGTCGGCTTCGACATCGCGGGCGCGGAGGCCGGCTACCC
GCCCACCCGCCACCTCGACGCGTTCGAGTACATGCGGGGCAACAACGCGCGCTTCACGATTCACGCCGGTGAGGCATTCG
GCCTGCCGTCCATCCACGAGGCCATCGCGTTCTGCGGGGCCGACCGGTTGGGTCACGGCGTGCGCATCGTCGACGACATC
ACCGTGGCGCCGGACGGGCAGGTGAAACTGGGTCGACTGGCCGCGATCCTGCGGGACAAGCGCATCCCGCTCGAGCTGTG
CCCGAGCTCGAACGTGCAGACCGGGGCGGTGGCCAGTATCGCCGAGCATCCGTTCGACCTGCTGGCCCGCACCCGGTTCC
GCGTCACGGTCAACACCGACAACCGGCTGATGAGCGACACCTCAATGAGCCAGGAGATGCTGCGCCTGGTCGAGGCCTTC
GGCTACGGCTGGAGCGATCTGGCGCGGTTCACCATCAACGCGATGAAGTCGTCCTTCATCCCGTTCGATGAGCGGCTCGC
GCTCATCGACGACGTGATCAAACCCCGTTACGCCGTGCTCGCCGGGTGA

Upstream 100 bases:

>100_bases
GGTGGGGGACAGTGCCCCGCCGGCGCGTCCGCTGATCATCGACCGGATCACCGCGACAGGCTGAGAGGGTCCGGAGAGGG
ACCGTGAGGAGCATGTGCCG

Downstream 100 bases:

>100_bases
CGCGTCACTCCTGGCGCAGGCGGGACTCGACGAACGCCTCCAGCGCCTCCCACTGCTCGACCGCCTGGGCGTAGGGCGGT
TCGGGACGGTCGGCGGCATC

Product: adenosine deaminase

Products: NA

Alternate protein names: Adenosine aminohydrolase [H]

Number of amino acids: Translated: 362; Mature: 361

Protein sequence:

>362_residues
MTTPLTLENISQAPKALLHDHLDGGLRPSTVLELAGQYGYDDLPADDVDELATFFRTAAHSGSLVRYLEPFAHTVGVMQT
AEALHRVAFECVEDLAGDNVVYAEVRFAPELHIEGGMGLDAVVDAVLAGFADGEKAAASAGRTITVRCLVTAMRHAARSR
EIAELAIRFRDRGVVGFDIAGAEAGYPPTRHLDAFEYMRGNNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDI
TVAPDGQVKLGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLARTRFRVTVNTDNRLMSDTSMSQEMLRLVEAF
GYGWSDLARFTINAMKSSFIPFDERLALIDDVIKPRYAVLAG

Sequences:

>Translated_362_residues
MTTPLTLENISQAPKALLHDHLDGGLRPSTVLELAGQYGYDDLPADDVDELATFFRTAAHSGSLVRYLEPFAHTVGVMQT
AEALHRVAFECVEDLAGDNVVYAEVRFAPELHIEGGMGLDAVVDAVLAGFADGEKAAASAGRTITVRCLVTAMRHAARSR
EIAELAIRFRDRGVVGFDIAGAEAGYPPTRHLDAFEYMRGNNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDI
TVAPDGQVKLGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLARTRFRVTVNTDNRLMSDTSMSQEMLRLVEAF
GYGWSDLARFTINAMKSSFIPFDERLALIDDVIKPRYAVLAG
>Mature_361_residues
TTPLTLENISQAPKALLHDHLDGGLRPSTVLELAGQYGYDDLPADDVDELATFFRTAAHSGSLVRYLEPFAHTVGVMQTA
EALHRVAFECVEDLAGDNVVYAEVRFAPELHIEGGMGLDAVVDAVLAGFADGEKAAASAGRTITVRCLVTAMRHAARSRE
IAELAIRFRDRGVVGFDIAGAEAGYPPTRHLDAFEYMRGNNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDIT
VAPDGQVKLGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLARTRFRVTVNTDNRLMSDTSMSQEMLRLVEAFG
YGWSDLARFTINAMKSSFIPFDERLALIDDVIKPRYAVLAG

Specific function: Unknown

COG id: COG1816

COG function: function code F; Adenosine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenosine and AMP deaminases family [H]

Homologues:

Organism=Homo sapiens, GI47078295, Length=359, Percent_Identity=29.8050139275766, Blast_Score=138, Evalue=9e-33,
Organism=Escherichia coli, GI1787910, Length=340, Percent_Identity=31.4705882352941, Blast_Score=155, Evalue=4e-39,
Organism=Caenorhabditis elegans, GI17538512, Length=348, Percent_Identity=31.6091954022989, Blast_Score=125, Evalue=5e-29,
Organism=Caenorhabditis elegans, GI32565969, Length=348, Percent_Identity=31.6091954022989, Blast_Score=125, Evalue=5e-29,
Organism=Saccharomyces cerevisiae, GI6324188, Length=308, Percent_Identity=23.7012987012987, Blast_Score=69, Evalue=1e-12,
Organism=Drosophila melanogaster, GI24645260, Length=353, Percent_Identity=26.0623229461756, Blast_Score=86, Evalue=3e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001365
- InterPro:   IPR006330 [H]

Pfam domain/function: PF00962 A_deaminase [H]

EC number: =3.5.4.4 [H]

Molecular weight: Translated: 39293; Mature: 39162

Theoretical pI: Translated: 5.25; Mature: 5.25

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTPLTLENISQAPKALLHDHLDGGLRPSTVLELAGQYGYDDLPADDVDELATFFRTAAH
CCCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHC
SGSLVRYLEPFAHTVGVMQTAEALHRVAFECVEDLAGDNVVYAEVRFAPELHIEGGMGLD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCEEEECCCCCHH
AVVDAVLAGFADGEKAAASAGRTITVRCLVTAMRHAARSREIAELAIRFRDRGVVGFDIA
HHHHHHHHHCCCCHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEC
GAEAGYPPTRHLDAFEYMRGNNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDI
CCCCCCCCCCCCCHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHCHHHHCCCEEEEEEE
TVAPDGQVKLGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLARTRFRVTVNTD
EECCCCCCHHHHHHHHHHCCCCCEEECCCCCCCCCHHHHHHHCCHHHHHCCEEEEEECCC
NRLMSDTSMSQEMLRLVEAFGYGWSDLARFTINAMKSSFIPFDERLALIDDVIKPRYAVL
CCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHCC
AG
CC
>Mature Secondary Structure 
TTPLTLENISQAPKALLHDHLDGGLRPSTVLELAGQYGYDDLPADDVDELATFFRTAAH
CCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHC
SGSLVRYLEPFAHTVGVMQTAEALHRVAFECVEDLAGDNVVYAEVRFAPELHIEGGMGLD
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCEEEECCCCCHH
AVVDAVLAGFADGEKAAASAGRTITVRCLVTAMRHAARSREIAELAIRFRDRGVVGFDIA
HHHHHHHHHCCCCHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEC
GAEAGYPPTRHLDAFEYMRGNNARFTIHAGEAFGLPSIHEAIAFCGADRLGHGVRIVDDI
CCCCCCCCCCCCCHHHHHCCCCCEEEEECCCCCCCCHHHHHHHHHCHHHHCCCEEEEEEE
TVAPDGQVKLGRLAAILRDKRIPLELCPSSNVQTGAVASIAEHPFDLLARTRFRVTVNTD
EECCCCCCHHHHHHHHHHCCCCCEEECCCCCCCCCHHHHHHHCCHHHHHCCEEEEEECCC
NRLMSDTSMSQEMLRLVEAFGYGWSDLARFTINAMKSSFIPFDERLALIDDVIKPRYAVL
CCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHCC
AG
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA