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The map label for this gene is dfrA [H]

Identifier: 108797020

GI number: 108797020

Start: 49951

End: 50958

Strand: Direct

Name: dfrA [H]

Synonym: Mmcs_0039

Alternate gene names: 108797020

Gene position: 49951-50958 (Clockwise)

Preceding gene: 108797016

Following gene: 108797021

Centisome position: 0.88

GC content: 71.03

Gene sequence:

>1008_bases
GTGGGGAAGAAGCTCGTCATCGGGGCCAGCGGGTTCCTGGGCTCCCACGTCACGCGCCGACTGGTCGAGCGCGGCGACGA
CGTACGCGTGCTCATCCGCCACACCAGCTCGACCCGCGGCATCGACGGACTGCCCGTCGAATGCCACTACGGCGACATCT
TCGACGACGACGCCGTGCGCGCCGCGGTGGCGGGCTGCGACGTCGTCTACTACTGCGTGGTCGACGCCCGCGCATGGCTG
CGGGACCCGACACCGCTGTGGCGCACCAACGTCGAAGGGCTGCAACGGGTACTCGACGTCGTCGCCGACGCCGACCTGTA
CCGCTTCGTGTTCACCAGTTCCATCGCCACGATCGGCATCGCCGACTCCGGCCCGGCGACCGAGGAGCTGTCCCACAACT
GGCTCGACCGGGCGGGCGAGTACGTCCGGACCCGCGTCGCCGCCGAGGACCTGGTGCTGCGATACCACCGCGAACGGGCC
CTACCCGCGGTGGCGATGTGCGTGTCCAACACCTATGGCCCCGACGACTGGCTGCCGACACCGCACGGCGGACTCGTCGC
CGCCGCGGTGCGCGGGAAGCTGCCGTTCTACATCGACGGCGCCCAGGCCGAGGTGGTCGGTGTGCGCGATGCGGCCGATG
CCCTCATCCTGGCCGGCGAACGCGGACGACCGGGGGAGCGCTACATCGTCTCCGAACGGTTCATGACCGCCCGTGAGATC
TACCAGACCGCTTGCGCCGCAGTCGGAGTGACACCGCCACAGCGCGGTGTGCCGATCCGGGCGCTGGCTGCCGCCGCGGT
GCCCAGCGCGTGGCTGGCCCGCCTGCGCCGCCGCGACACCCGGTTCACGCCGCTGACCATCCGGCTCATGCACATCATGT
CGCCGATGGACCATTCCAAGGCCGAACGCGAACTCGGATGGCGTCCGGCACCCACGACGGATGCCCTCGCCGAGGCCGCG
GAGTTCTTCGTCGGCAACCGCCGCCGACCCGCCGAGGACCGCCGCTGA

Upstream 100 bases:

>100_bases
TGGCGCAGCAGTCACCCCGTCGGGCATTGCGGGCTGGGTCATCGCCCCGTAGTCTGCCACAGACGAGACGAACCGTCTCG
TCTCGAAGAGCAGGAGTTCC

Downstream 100 bases:

>100_bases
TGCCGATCGCCCTGACCCCGGAACAGCGGGCGCTCTCCGACGCGGTGCGCGAGTTCGCCGCCCGCCACGCCCCGGTCGAG
AAGACCCGCCAGGCCTTCGA

Product: NAD-dependent epimerase/dehydratase

Products: NA

Alternate protein names: DFR; Dihydrokaempferol 4-reductase [H]

Number of amino acids: Translated: 335; Mature: 334

Protein sequence:

>335_residues
MGKKLVIGASGFLGSHVTRRLVERGDDVRVLIRHTSSTRGIDGLPVECHYGDIFDDDAVRAAVAGCDVVYYCVVDARAWL
RDPTPLWRTNVEGLQRVLDVVADADLYRFVFTSSIATIGIADSGPATEELSHNWLDRAGEYVRTRVAAEDLVLRYHRERA
LPAVAMCVSNTYGPDDWLPTPHGGLVAAAVRGKLPFYIDGAQAEVVGVRDAADALILAGERGRPGERYIVSERFMTAREI
YQTACAAVGVTPPQRGVPIRALAAAAVPSAWLARLRRRDTRFTPLTIRLMHIMSPMDHSKAERELGWRPAPTTDALAEAA
EFFVGNRRRPAEDRR

Sequences:

>Translated_335_residues
MGKKLVIGASGFLGSHVTRRLVERGDDVRVLIRHTSSTRGIDGLPVECHYGDIFDDDAVRAAVAGCDVVYYCVVDARAWL
RDPTPLWRTNVEGLQRVLDVVADADLYRFVFTSSIATIGIADSGPATEELSHNWLDRAGEYVRTRVAAEDLVLRYHRERA
LPAVAMCVSNTYGPDDWLPTPHGGLVAAAVRGKLPFYIDGAQAEVVGVRDAADALILAGERGRPGERYIVSERFMTAREI
YQTACAAVGVTPPQRGVPIRALAAAAVPSAWLARLRRRDTRFTPLTIRLMHIMSPMDHSKAERELGWRPAPTTDALAEAA
EFFVGNRRRPAEDRR
>Mature_334_residues
GKKLVIGASGFLGSHVTRRLVERGDDVRVLIRHTSSTRGIDGLPVECHYGDIFDDDAVRAAVAGCDVVYYCVVDARAWLR
DPTPLWRTNVEGLQRVLDVVADADLYRFVFTSSIATIGIADSGPATEELSHNWLDRAGEYVRTRVAAEDLVLRYHRERAL
PAVAMCVSNTYGPDDWLPTPHGGLVAAAVRGKLPFYIDGAQAEVVGVRDAADALILAGERGRPGERYIVSERFMTAREIY
QTACAAVGVTPPQRGVPIRALAAAAVPSAWLARLRRRDTRFTPLTIRLMHIMSPMDHSKAERELGWRPAPTTDALAEAAE
FFVGNRRRPAEDRR

Specific function: Unknown

COG id: COG0451

COG function: function code MG; Nucleoside-diphosphate-sugar epimerases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dihydroflavonol-4-reductase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001509
- InterPro:   IPR017829
- InterPro:   IPR016040 [H]

Pfam domain/function: PF01370 Epimerase [H]

EC number: =1.1.1.219 [H]

Molecular weight: Translated: 36913; Mature: 36782

Theoretical pI: Translated: 7.92; Mature: 7.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGKKLVIGASGFLGSHVTRRLVERGDDVRVLIRHTSSTRGIDGLPVECHYGDIFDDDAVR
CCCEEEEECCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCEEEECCCCCCCHHHH
AAVAGCDVVYYCVVDARAWLRDPTPLWRTNVEGLQRVLDVVADADLYRFVFTSSIATIGI
HHHHHCCEEEEHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHEEEE
ADSGPATEELSHNWLDRAGEYVRTRVAAEDLVLRYHRERALPAVAMCVSNTYGPDDWLPT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCC
PHGGLVAAAVRGKLPFYIDGAQAEVVGVRDAADALILAGERGRPGERYIVSERFMTAREI
CCCCEEEHHHHCCCCEEECCCCEEEEECCCCCCEEEEECCCCCCCCEEEHHHHHHHHHHH
YQTACAAVGVTPPQRGVPIRALAAAAVPSAWLARLRRRDTRFTPLTIRLMHIMSPMDHSK
HHHHHHHCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHH
AERELGWRPAPTTDALAEAAEFFVGNRRRPAEDRR
HHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
GKKLVIGASGFLGSHVTRRLVERGDDVRVLIRHTSSTRGIDGLPVECHYGDIFDDDAVR
CCEEEEECCCHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCCCCEEEECCCCCCCHHHH
AAVAGCDVVYYCVVDARAWLRDPTPLWRTNVEGLQRVLDVVADADLYRFVFTSSIATIGI
HHHHHCCEEEEHHHHHHHHHCCCCCHHHCCHHHHHHHHHHHHCCHHHHHHHHHHHHEEEE
ADSGPATEELSHNWLDRAGEYVRTRVAAEDLVLRYHRERALPAVAMCVSNTYGPDDWLPT
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCC
PHGGLVAAAVRGKLPFYIDGAQAEVVGVRDAADALILAGERGRPGERYIVSERFMTAREI
CCCCEEEHHHHCCCCEEECCCCEEEEECCCCCCEEEEECCCCCCCCEEEHHHHHHHHHHH
YQTACAAVGVTPPQRGVPIRALAAAAVPSAWLARLRRRDTRFTPLTIRLMHIMSPMDHSK
HHHHHHHCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHHCCCCHHH
AERELGWRPAPTTDALAEAAEFFVGNRRRPAEDRR
HHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]