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The map label for this gene is atoS [H]

Identifier: 108763457

GI number: 108763457

Start: 3972921

End: 3974396

Strand: Reverse

Name: atoS [H]

Synonym: MXAN_3419

Alternate gene names: 108763457

Gene position: 3974396-3972921 (Counterclockwise)

Preceding gene: 108762119

Following gene: 108763676

Centisome position: 43.48

GC content: 68.9

Gene sequence:

>1476_bases
TTGGCCTGCCTGTTGCTAAATCCCTACCTTCGTTCGCCAGGGGATGTCGTGTCCGGAACCGCTCGCAGGCTCTTATACGC
CTTCTCGCTCCTCGTCCTGACCTTCGGCGCGGCAGCCTATGCCGCGCTCGAGGGCATGGCGGAGATCCACGAGGCCCTGC
ACAGCGTGCGGCGGCAGGAAACGGCCGTGCGCACCACGCTGTCGCTCGCGACCTCGGTGCGAGACCTCTACGCACACCAG
GCGCACACCGTCATCCTCGGCAACGCCAGCCACCTGCCGCTCTATGACAGCGCCTATCACCGTGCCATGGAGCGGCTCGA
AGCGGTACAAGCCCAGGCCACCACCTCCGAGGAACGCGCCCAGGTGGAGACCATGCGCCGCACCACGACGGAGCTGGACC
GGCTTTTCCGCGAGGCGCTCGTGCCAGCCGTGCTGCGCGAGGACCACGCCACCGCGGCCCGTGAACACGCCAGGGCCCTG
GAACTGGTCGACGTCATCCAGGAGAGCGCGGACACCCTGGCCTCGCACTACGAGCGCGCCATTGGCAACTTCGAGGAGCA
CGCGAGCACGGTCCAGCACGCCAGCTTCCAGTGGACGGTCGCCATCCTGGCCGCCGCCGCCCTGCTCGCGGCGGGCGTAG
GCCTCTACATCGGCCGCTCGGTGGCCCGCCCGGTTTCACTGCTGGAGGCCGGCGCGGCCCGTATCGCCGCGGGCGACCTC
ATGACTCGCATCGCGCTGGACCGCCCGGATGAGTTCGGAAGGCTGGCGCAGCAGTTCAACCGGATGACCGCCGCGCTACG
CGAGCACCAGGAGCGCCTGGTTCAAAGCGAGCGGCTGGCGGGCATCGGCCGCCTCGCGGCGGGCGTGGCGCATGAAATCA
ACAATCCCCTAGGGGTCATCCTCGGCTACGTGCGCCTGCTTCAGCGCAAGGCGGAGGGTGCGCTCGCGGACGACCTGCGC
ATCATCGAAGAGGAGACGCTGCGCTGCCGTGACATCGTGGAGGGGATGCTCGACCTGTCGCGGCCCCTCCAGGTCCCGGG
CGAGACGCTGGAGCTGCGAGAGCTGGTGGAGGAAGTCGTCTCCCGGCAGCGGGAGTCCGCCCAGCACTCCGCGGCATCCC
TGACGGTGGAAGGCGAAGCCCAGGTGGCAGGGCATCCGCAGCGGCTGCGGCAGGTGGTCACGAACCTGGTCAAGAACGCC
ATGGAGGCCGCAGGTCCCTCTGGACAGGTGACAGTGGCCATCCAGGCCCACGAAGGCGAGGTGGCGCTTTCATTCCGCGA
CAGCGGGCCCGGCCTCTCTCCCGAGGCACAGAAGCGGATGTTCGAGCCCTTCTTCACCACCAAACCCCATGGCACCGGGC
TGGGGTTGGCGGTGTCGCAGGCCATCGCCCAGGCCCATGGTGGGCGCATCCAGCCGCGCAACCTGCCTGGACGTGGTGCG
GAATTCACCCTGCATCTCCCCCGGAGTACGCCGTGA

Upstream 100 bases:

>100_bases
CATTACAGTGTGACCAGCCTGGTCACACCCGGCCCTTTTCTCGCAACGATGAGGGAACGCCGCCCAGGAATGAGTTCAGC
CACTTGCAGCGCGCACCACA

Downstream 100 bases:

>100_bases
CGGACAGACCGAGTGTTCTCGTTGTCGACGACAAGGAGAACATGCGCCACCTCATCACCCGCATTCTCGGTGACGCTTAT
CAGGTGAGGACGGCTGAAGA

Product: sensor histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 491; Mature: 490

Protein sequence:

>491_residues
MACLLLNPYLRSPGDVVSGTARRLLYAFSLLVLTFGAAAYAALEGMAEIHEALHSVRRQETAVRTTLSLATSVRDLYAHQ
AHTVILGNASHLPLYDSAYHRAMERLEAVQAQATTSEERAQVETMRRTTTELDRLFREALVPAVLREDHATAAREHARAL
ELVDVIQESADTLASHYERAIGNFEEHASTVQHASFQWTVAILAAAALLAAGVGLYIGRSVARPVSLLEAGAARIAAGDL
MTRIALDRPDEFGRLAQQFNRMTAALREHQERLVQSERLAGIGRLAAGVAHEINNPLGVILGYVRLLQRKAEGALADDLR
IIEEETLRCRDIVEGMLDLSRPLQVPGETLELRELVEEVVSRQRESAQHSAASLTVEGEAQVAGHPQRLRQVVTNLVKNA
MEAAGPSGQVTVAIQAHEGEVALSFRDSGPGLSPEAQKRMFEPFFTTKPHGTGLGLAVSQAIAQAHGGRIQPRNLPGRGA
EFTLHLPRSTP

Sequences:

>Translated_491_residues
MACLLLNPYLRSPGDVVSGTARRLLYAFSLLVLTFGAAAYAALEGMAEIHEALHSVRRQETAVRTTLSLATSVRDLYAHQ
AHTVILGNASHLPLYDSAYHRAMERLEAVQAQATTSEERAQVETMRRTTTELDRLFREALVPAVLREDHATAAREHARAL
ELVDVIQESADTLASHYERAIGNFEEHASTVQHASFQWTVAILAAAALLAAGVGLYIGRSVARPVSLLEAGAARIAAGDL
MTRIALDRPDEFGRLAQQFNRMTAALREHQERLVQSERLAGIGRLAAGVAHEINNPLGVILGYVRLLQRKAEGALADDLR
IIEEETLRCRDIVEGMLDLSRPLQVPGETLELRELVEEVVSRQRESAQHSAASLTVEGEAQVAGHPQRLRQVVTNLVKNA
MEAAGPSGQVTVAIQAHEGEVALSFRDSGPGLSPEAQKRMFEPFFTTKPHGTGLGLAVSQAIAQAHGGRIQPRNLPGRGA
EFTLHLPRSTP
>Mature_490_residues
ACLLLNPYLRSPGDVVSGTARRLLYAFSLLVLTFGAAAYAALEGMAEIHEALHSVRRQETAVRTTLSLATSVRDLYAHQA
HTVILGNASHLPLYDSAYHRAMERLEAVQAQATTSEERAQVETMRRTTTELDRLFREALVPAVLREDHATAAREHARALE
LVDVIQESADTLASHYERAIGNFEEHASTVQHASFQWTVAILAAAALLAAGVGLYIGRSVARPVSLLEAGAARIAAGDLM
TRIALDRPDEFGRLAQQFNRMTAALREHQERLVQSERLAGIGRLAAGVAHEINNPLGVILGYVRLLQRKAEGALADDLRI
IEEETLRCRDIVEGMLDLSRPLQVPGETLELRELVEEVVSRQRESAQHSAASLTVEGEAQVAGHPQRLRQVVTNLVKNAM
EAAGPSGQVTVAIQAHEGEVALSFRDSGPGLSPEAQKRMFEPFFTTKPHGTGLGLAVSQAIAQAHGGRIQPRNLPGRGAE
FTLHLPRSTP

Specific function: Member of the two-component regulatory system AtoS/AtoC; may activate AtoC by phosphorylation [H]

COG id: COG0642

COG function: function code T; Signal transduction histidine kinase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=234, Percent_Identity=36.7521367521368, Blast_Score=149, Evalue=4e-37,
Organism=Escherichia coli, GI1790436, Length=223, Percent_Identity=35.4260089686099, Blast_Score=129, Evalue=4e-31,
Organism=Escherichia coli, GI1788393, Length=282, Percent_Identity=27.6595744680851, Blast_Score=105, Evalue=7e-24,
Organism=Escherichia coli, GI1790346, Length=279, Percent_Identity=29.3906810035842, Blast_Score=102, Evalue=6e-23,
Organism=Escherichia coli, GI87081816, Length=375, Percent_Identity=28, Blast_Score=100, Evalue=2e-22,
Organism=Escherichia coli, GI1790300, Length=255, Percent_Identity=28.6274509803922, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1789149, Length=341, Percent_Identity=25.8064516129032, Blast_Score=93, Evalue=3e-20,
Organism=Escherichia coli, GI1789808, Length=281, Percent_Identity=27.7580071174377, Blast_Score=89, Evalue=8e-19,
Organism=Escherichia coli, GI1786600, Length=230, Percent_Identity=28.2608695652174, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1787894, Length=309, Percent_Identity=29.126213592233, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI145693157, Length=216, Percent_Identity=28.2407407407407, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1786912, Length=250, Percent_Identity=32.4, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1786783, Length=301, Percent_Identity=27.906976744186, Blast_Score=76, Evalue=4e-15,
Organism=Escherichia coli, GI48994928, Length=218, Percent_Identity=27.5229357798165, Blast_Score=74, Evalue=2e-14,
Organism=Escherichia coli, GI87082128, Length=313, Percent_Identity=23.961661341853, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1790861, Length=319, Percent_Identity=25.705329153605, Blast_Score=64, Evalue=2e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 53361; Mature: 53230

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MACLLLNPYLRSPGDVVSGTARRLLYAFSLLVLTFGAAAYAALEGMAEIHEALHSVRRQE
CEEEEECHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAVRTTLSLATSVRDLYAHQAHTVILGNASHLPLYDSAYHRAMERLEAVQAQATTSEERA
HHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHH
QVETMRRTTTELDRLFREALVPAVLREDHATAAREHARALELVDVIQESADTLASHYERA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGNFEEHASTVQHASFQWTVAILAAAALLAAGVGLYIGRSVARPVSLLEAGAARIAAGDL
HCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MTRIALDRPDEFGRLAQQFNRMTAALREHQERLVQSERLAGIGRLAAGVAHEINNPLGVI
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
LGYVRLLQRKAEGALADDLRIIEEETLRCRDIVEGMLDLSRPLQVPGETLELRELVEEVV
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
SRQRESAQHSAASLTVEGEAQVAGHPQRLRQVVTNLVKNAMEAAGPSGQVTVAIQAHEGE
HHHHHHHHHHHHEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCC
VALSFRDSGPGLSPEAQKRMFEPFFTTKPHGTGLGLAVSQAIAQAHGGRIQPRNLPGRGA
EEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCC
EFTLHLPRSTP
EEEEECCCCCC
>Mature Secondary Structure 
ACLLLNPYLRSPGDVVSGTARRLLYAFSLLVLTFGAAAYAALEGMAEIHEALHSVRRQE
EEEEECHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TAVRTTLSLATSVRDLYAHQAHTVILGNASHLPLYDSAYHRAMERLEAVQAQATTSEERA
HHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHH
QVETMRRTTTELDRLFREALVPAVLREDHATAAREHARALELVDVIQESADTLASHYERA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IGNFEEHASTVQHASFQWTVAILAAAALLAAGVGLYIGRSVARPVSLLEAGAARIAAGDL
HCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MTRIALDRPDEFGRLAQQFNRMTAALREHQERLVQSERLAGIGRLAAGVAHEINNPLGVI
HHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
LGYVRLLQRKAEGALADDLRIIEEETLRCRDIVEGMLDLSRPLQVPGETLELRELVEEVV
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHH
SRQRESAQHSAASLTVEGEAQVAGHPQRLRQVVTNLVKNAMEAAGPSGQVTVAIQAHEGE
HHHHHHHHHHHHEEEECCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCC
VALSFRDSGPGLSPEAQKRMFEPFFTTKPHGTGLGLAVSQAIAQAHGGRIQPRNLPGRGA
EEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCC
EFTLHLPRSTP
EEEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8346225; 9097040; 9278503 [H]