Click here to switch to the map view.

The map label for this gene is dnaX [H]

Identifier: 108761627

GI number: 108761627

Start: 2267268

End: 2268476

Strand: Reverse

Name: dnaX [H]

Synonym: MXAN_1933

Alternate gene names: 108761627

Gene position: 2268476-2267268 (Counterclockwise)

Preceding gene: 108758559

Following gene: 108757583

Centisome position: 24.82

GC content: 67.08

Gene sequence:

>1209_bases
ATGAGCTACCTCGTTCTCGCCCGCAAATGGCGCCCACAGAAGTTCGACGACATGACCGGACAGGAGCACGTCGTCCGGAC
GGTCGCGAACGCCATCAAGATAGACCGGGTCGCGCACGCGTACCTGTTCTGTGGACCTCGTGGCGTGGGCAAGACGACGG
CCGCGCGGCTGCTCGCCAAGGCGCTCAACTGTGAGAAGGGCCCCACCGCCCAGCCCTGTGGCGAGTGCCGTGCTTGCACG
GAGATTGCCGCCGGCACCAGCGTGGACGTCGCGGAAATCGACGGTGCCTCCAACAACGGCGTCGAGAACGTCCGCGAGAT
TCGCGAGAACGCGAAGTACCTGCCCCAGCGGGACCGGCACAAAATCTACATCATCGACGAGGTCCACATGCTGTCGGGAG
CGGCGTTCAACGCGCTGCTCAAGACGCTGGAGGAGCCGCCCGGGCACGTGAAGTTCATCTTCGCGACCACCGAGGCGCAC
AAGCTCCCGGACACCATCCTGTCGCGGTGCCAGCGCCACAACTTCCGGCGGATTCCGGCGGCCCGGATGCTTCAGCGTCT
CCAGGAAATCTGCAAGGCGGAGGGCGCTGGTATCTCCGACCGCTCGCTGTCGCTGGTCGTGCGCCAGTCCGAAGGCGGCA
TGCGCGATGCGCTGAGCCTCCTGGACCAGGTGCTCGCCTCGTGCGGCGCCACCCCCTCCGACGAGGAAGTGGCCGATGCG
CTGGGCGCCATCGACCGGACGTTGGTGCAGGACTTCGCCGATGCGCTCGTCCACAAGGACGCGAAGCGGGTGTTGGAGCG
GGTGGAGGAAGTCTTCAACCGCGGCCTGGACTTGAAGCGCCTGGCCGAGGAGCTGGCCTTCCAACTGCGGCATCTCTTCG
TCACCAAGACGCTGGGCAAGGCGCCCGACGAGCTGGCCGAGTCCGAGCAGAAGGCGCTGATGGCGCTGGCGCAGGACGCG
GAGGCCGCGCAGCTCACGCGCTTGTTCGACGTGGTGCACGGCTGCATCTGGGACGTGTCGCGTGCGGCCCAGCCTCGGCT
GGCCCTGGAGATGGCGCTGCTCAAGGCCATCCAGTTGTCGCCGGGTGGTTCGATTCCCGAGCTGCTTGCCCGCGTGGACA
AGCTCGCGGCGGGGATGGGTGAAGGTTCCGCGAAGTCGAACGCTGGAGCGCCGGGAGGTCGCTCCAGTCCCACGAACTTT
CGCGCCTGA

Upstream 100 bases:

>100_bases
TGCCCGCCCTGGGTCCGAGCCCGACGGGGAGTGGAATCCCACCTCGTGGGAGGGCAACGACATGGATCATTCACGCCGCC
GTGTTTAGATGACGCCCCCC

Downstream 100 bases:

>100_bases
GACACGACTCGACACTTCCGTGATGCAGGCGGCTGCCCCCACCCCACGTCCGTGGGAAGCGAGGGGTGCGCCCGTGGCGC
AGATGCCTGTGCGCGCCAAC

Product: DNA polymerase III subunits gamma and tau, truncated

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 402; Mature: 401

Protein sequence:

>402_residues
MSYLVLARKWRPQKFDDMTGQEHVVRTVANAIKIDRVAHAYLFCGPRGVGKTTAARLLAKALNCEKGPTAQPCGECRACT
EIAAGTSVDVAEIDGASNNGVENVREIRENAKYLPQRDRHKIYIIDEVHMLSGAAFNALLKTLEEPPGHVKFIFATTEAH
KLPDTILSRCQRHNFRRIPAARMLQRLQEICKAEGAGISDRSLSLVVRQSEGGMRDALSLLDQVLASCGATPSDEEVADA
LGAIDRTLVQDFADALVHKDAKRVLERVEEVFNRGLDLKRLAEELAFQLRHLFVTKTLGKAPDELAESEQKALMALAQDA
EAAQLTRLFDVVHGCIWDVSRAAQPRLALEMALLKAIQLSPGGSIPELLARVDKLAAGMGEGSAKSNAGAPGGRSSPTNF
RA

Sequences:

>Translated_402_residues
MSYLVLARKWRPQKFDDMTGQEHVVRTVANAIKIDRVAHAYLFCGPRGVGKTTAARLLAKALNCEKGPTAQPCGECRACT
EIAAGTSVDVAEIDGASNNGVENVREIRENAKYLPQRDRHKIYIIDEVHMLSGAAFNALLKTLEEPPGHVKFIFATTEAH
KLPDTILSRCQRHNFRRIPAARMLQRLQEICKAEGAGISDRSLSLVVRQSEGGMRDALSLLDQVLASCGATPSDEEVADA
LGAIDRTLVQDFADALVHKDAKRVLERVEEVFNRGLDLKRLAEELAFQLRHLFVTKTLGKAPDELAESEQKALMALAQDA
EAAQLTRLFDVVHGCIWDVSRAAQPRLALEMALLKAIQLSPGGSIPELLARVDKLAAGMGEGSAKSNAGAPGGRSSPTNF
RA
>Mature_401_residues
SYLVLARKWRPQKFDDMTGQEHVVRTVANAIKIDRVAHAYLFCGPRGVGKTTAARLLAKALNCEKGPTAQPCGECRACTE
IAAGTSVDVAEIDGASNNGVENVREIRENAKYLPQRDRHKIYIIDEVHMLSGAAFNALLKTLEEPPGHVKFIFATTEAHK
LPDTILSRCQRHNFRRIPAARMLQRLQEICKAEGAGISDRSLSLVVRQSEGGMRDALSLLDQVLASCGATPSDEEVADAL
GAIDRTLVQDFADALVHKDAKRVLERVEEVFNRGLDLKRLAEELAFQLRHLFVTKTLGKAPDELAESEQKALMALAQDAE
AAQLTRLFDVVHGCIWDVSRAAQPRLALEMALLKAIQLSPGGSIPELLARVDKLAAGMGEGSAKSNAGAPGGRSSPTNFR
A

Specific function: DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria [H]

COG id: COG2812

COG function: function code L; DNA polymerase III, gamma/tau subunits

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Homo sapiens, GI194306571, Length=302, Percent_Identity=24.5033112582781, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI194306567, Length=302, Percent_Identity=24.5033112582781, Blast_Score=84, Evalue=3e-16,
Organism=Homo sapiens, GI6677723, Length=299, Percent_Identity=25.0836120401338, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI31563534, Length=234, Percent_Identity=26.0683760683761, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI4506491, Length=300, Percent_Identity=25.3333333333333, Blast_Score=79, Evalue=8e-15,
Organism=Homo sapiens, GI31881687, Length=300, Percent_Identity=25.3333333333333, Blast_Score=79, Evalue=8e-15,
Organism=Escherichia coli, GI1786676, Length=369, Percent_Identity=43.0894308943089, Blast_Score=290, Evalue=2e-79,
Organism=Escherichia coli, GI1787341, Length=147, Percent_Identity=35.3741496598639, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1787119, Length=235, Percent_Identity=26.8085106382979, Blast_Score=62, Evalue=7e-11,
Organism=Caenorhabditis elegans, GI17554730, Length=269, Percent_Identity=28.6245353159851, Blast_Score=89, Evalue=3e-18,
Organism=Caenorhabditis elegans, GI17541988, Length=222, Percent_Identity=27.9279279279279, Blast_Score=80, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI71986063, Length=291, Percent_Identity=24.7422680412371, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6324039, Length=241, Percent_Identity=28.2157676348548, Blast_Score=90, Evalue=6e-19,
Organism=Saccharomyces cerevisiae, GI6322528, Length=273, Percent_Identity=26.3736263736264, Blast_Score=82, Evalue=2e-16,
Organism=Saccharomyces cerevisiae, GI6324478, Length=231, Percent_Identity=25.974025974026, Blast_Score=81, Evalue=2e-16,
Organism=Drosophila melanogaster, GI19921076, Length=337, Percent_Identity=24.0356083086053, Blast_Score=84, Evalue=2e-16,
Organism=Drosophila melanogaster, GI17647857, Length=223, Percent_Identity=28.2511210762332, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI18859927, Length=303, Percent_Identity=23.7623762376238, Blast_Score=76, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR003959
- InterPro:   IPR001270
- InterPro:   IPR008921
- InterPro:   IPR022754
- InterPro:   IPR012763 [H]

Pfam domain/function: PF00004 AAA; PF12169 DNA_pol3_gamma3 [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 43731; Mature: 43599

Theoretical pI: Translated: 7.76; Mature: 7.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSYLVLARKWRPQKFDDMTGQEHVVRTVANAIKIDRVAHAYLFCGPRGVGKTTAARLLAK
CCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHH
ALNCEKGPTAQPCGECRACTEIAAGTSVDVAEIDGASNNGVENVREIRENAKYLPQRDRH
HHCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCC
KIYIIDEVHMLSGAAFNALLKTLEEPPGHVKFIFATTEAHKLPDTILSRCQRHNFRRIPA
EEEEEEHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECHHHCCHHHHHHHHHHCCCCCCCH
ARMLQRLQEICKAEGAGISDRSLSLVVRQSEGGMRDALSLLDQVLASCGATPSDEEVADA
HHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHH
LGAIDRTLVQDFADALVHKDAKRVLERVEEVFNRGLDLKRLAEELAFQLRHLFVTKTLGK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCC
APDELAESEQKALMALAQDAEAAQLTRLFDVVHGCIWDVSRAAQPRLALEMALLKAIQLS
CCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCC
PGGSIPELLARVDKLAAGMGEGSAKSNAGAPGGRSSPTNFRA
CCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SYLVLARKWRPQKFDDMTGQEHVVRTVANAIKIDRVAHAYLFCGPRGVGKTTAARLLAK
CCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHHHHHHHH
ALNCEKGPTAQPCGECRACTEIAAGTSVDVAEIDGASNNGVENVREIRENAKYLPQRDRH
HHCCCCCCCCCCHHHHHHHHHHHCCCCCCHHHCCCCCCCCHHHHHHHHHHHHCCCCCCCC
KIYIIDEVHMLSGAAFNALLKTLEEPPGHVKFIFATTEAHKLPDTILSRCQRHNFRRIPA
EEEEEEHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECHHHCCHHHHHHHHHHCCCCCCCH
ARMLQRLQEICKAEGAGISDRSLSLVVRQSEGGMRDALSLLDQVLASCGATPSDEEVADA
HHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHH
LGAIDRTLVQDFADALVHKDAKRVLERVEEVFNRGLDLKRLAEELAFQLRHLFVTKTLGK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCC
APDELAESEQKALMALAQDAEAAQLTRLFDVVHGCIWDVSRAAQPRLALEMALLKAIQLS
CCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCC
PGGSIPELLARVDKLAAGMGEGSAKSNAGAPGGRSSPTNFRA
CCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 2124672; 7584024; 9384377; 2452406; 2468993; 1698458 [H]