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The map label for this gene is tadA [H]

Identifier: 108758559

GI number: 108758559

Start: 2270470

End: 2270934

Strand: Reverse

Name: tadA [H]

Synonym: MXAN_1937

Alternate gene names: 108758559

Gene position: 2270934-2270470 (Counterclockwise)

Preceding gene: 108757304

Following gene: 108761627

Centisome position: 24.85

GC content: 61.08

Gene sequence:

>465_bases
ATGAGTGACGAAGCTTTCATGCAGCAGGCGCTATCGCTCGCGCGGGAAGCAGCGGAACTCGGAGAGGTCCCCGTAGGTGC
GGTGGCGGTGCTCAACGGTGAAGTCGTTGGCGCTGGATTCAATCGCCGCGAAGTGGACCGCAATCCGCTCGCTCACGCAG
AGATGTTGGCAATGGACGCCGCAGCCCGGAAGATCGGTGCCTGGCGGCTCTCGGGCGTCACCCTGTATGTGACACTTGAG
CCGTGTGCCATGTGCGCCGGAGGTCTGGTGCAGTCTCGCGTGACACGACTCGTTTTCGGTGCCTTCGATCCGAAAGCGGG
TGCGGTGGGTTCGCTGTACAACCTGGTCGAAGAGCCTCGACACAATCACCGGCTCCAAGTCACGAGTGGTATCCTGGCGG
ACGAGAGCCGCCTGCTTTTGAAGACGTTTTTCGGGCGCTTGCGTGCGAAGAAACGTGACAATTGA

Upstream 100 bases:

>100_bases
AATGCTCCCTTAGCTCAGCTGGATAGAGCGTCGGACTACGAATCCGAAGGCCGGAGGTTCGAATCCTCCAGGGAGCGCCA
CTTCTTTCGAGCAGTTCTCC

Downstream 100 bases:

>100_bases
ATACTGGAGAGCTGGCCGAGTGGTCGAAGGCACCTGACTCGAAATCAGGCATACCGGTAACGGTATCGTAGGTTCGAATC
CTACGCTCTCCGCTCCAGAT

Product: cytidine and deoxycytidylate deaminase zinc-binding domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 154; Mature: 153

Protein sequence:

>154_residues
MSDEAFMQQALSLAREAAELGEVPVGAVAVLNGEVVGAGFNRREVDRNPLAHAEMLAMDAAARKIGAWRLSGVTLYVTLE
PCAMCAGGLVQSRVTRLVFGAFDPKAGAVGSLYNLVEEPRHNHRLQVTSGILADESRLLLKTFFGRLRAKKRDN

Sequences:

>Translated_154_residues
MSDEAFMQQALSLAREAAELGEVPVGAVAVLNGEVVGAGFNRREVDRNPLAHAEMLAMDAAARKIGAWRLSGVTLYVTLE
PCAMCAGGLVQSRVTRLVFGAFDPKAGAVGSLYNLVEEPRHNHRLQVTSGILADESRLLLKTFFGRLRAKKRDN
>Mature_153_residues
SDEAFMQQALSLAREAAELGEVPVGAVAVLNGEVVGAGFNRREVDRNPLAHAEMLAMDAAARKIGAWRLSGVTLYVTLEP
CAMCAGGLVQSRVTRLVFGAFDPKAGAVGSLYNLVEEPRHNHRLQVTSGILADESRLLLKTFFGRLRAKKRDN

Specific function: Deaminates adenosine-34 to inosine in tRNA-Arg2 [H]

COG id: COG0590

COG function: function code FJ; Cytosine/adenosine deaminases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytidine and deoxycytidylate deaminase family [H]

Homologues:

Organism=Homo sapiens, GI124107608, Length=155, Percent_Identity=36.7741935483871, Blast_Score=96, Evalue=2e-20,
Organism=Homo sapiens, GI19923945, Length=155, Percent_Identity=32.258064516129, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI145693172, Length=150, Percent_Identity=49.3333333333333, Blast_Score=145, Evalue=2e-36,
Organism=Escherichia coli, GI1786616, Length=157, Percent_Identity=33.1210191082803, Blast_Score=65, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17541138, Length=148, Percent_Identity=39.1891891891892, Blast_Score=105, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17554608, Length=124, Percent_Identity=33.0645161290323, Blast_Score=81, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17555996, Length=120, Percent_Identity=35, Blast_Score=75, Evalue=2e-14,
Organism=Saccharomyces cerevisiae, GI6322425, Length=153, Percent_Identity=31.3725490196078, Blast_Score=74, Evalue=1e-14,
Organism=Drosophila melanogaster, GI21355527, Length=148, Percent_Identity=38.5135135135135, Blast_Score=88, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1 [H]

EC number: NA

Molecular weight: Translated: 16649; Mature: 16518

Theoretical pI: Translated: 8.76; Mature: 8.76

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.5 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSDEAFMQQALSLAREAAELGEVPVGAVAVLNGEVVGAGFNRREVDRNPLAHAEMLAMDA
CCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCEEEECCCCCCCCCCCCCHHHHHHHHHH
AARKIGAWRLSGVTLYVTLEPCAMCAGGLVQSRVTRLVFGAFDPKAGAVGSLYNLVEEPR
HHHHHCCEEECCEEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCC
HNHRLQVTSGILADESRLLLKTFFGRLRAKKRDN
CCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SDEAFMQQALSLAREAAELGEVPVGAVAVLNGEVVGAGFNRREVDRNPLAHAEMLAMDA
CHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCEEEECCCCCCCCCCCCCHHHHHHHHHH
AARKIGAWRLSGVTLYVTLEPCAMCAGGLVQSRVTRLVFGAFDPKAGAVGSLYNLVEEPR
HHHHHCCEEECCEEEEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHCCC
HNHRLQVTSGILADESRLLLKTFFGRLRAKKRDN
CCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1698458; 7584024; 9384377 [H]