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The map label for this gene is ygfA [H]

Identifier: 108760545

GI number: 108760545

Start: 3492361

End: 3492999

Strand: Reverse

Name: ygfA [H]

Synonym: MXAN_2978

Alternate gene names: 108760545

Gene position: 3492999-3492361 (Counterclockwise)

Preceding gene: 108763530

Following gene: 108761547

Centisome position: 38.22

GC content: 65.57

Gene sequence:

>639_bases
TTGGGAGCGGCGTCGGTGAGCGAGACGGTGGTGGAAGAGGCGGCGGCGAGGAAGCAGACCCTGCGAGAGGAGCTCACGGC
GCGCCGGAAGGCGATGACGCCGGACCTCATCGATACGCGGGGTCTCAAGGTTCAGTCTCGGTTTCTGGCGGCGCCCTACT
ATCAGAAGGCGCGCACGGTGGCGTTGTACGCCCCCATTCGGGGGGAAGTGCCAACCCGGGATATCCTGATTGCGGCGTTG
CAAGACGGCAAGATTGTCTGCTACCCGCTCTCACATGTTCACGGGCGGATTCTTTCGTTCCGTGCCATCAAGTCGGAAAG
CGAGCTGGAACCGGGACGTTTGGGGGTGCGTGAGCCCACCAACTCCGCGGACCTCATCGCGGTGGACCAGATTGACCTCT
TCGTGGTGCCGGGCCTGGGCTTCACCCGGGAAGGCAAGCGGCTGGGGCGCGGGGGCGGTTACTACGACGCCACCCTCCGC
GCGGCCAGTCAGCGCAGTCGTCGGGTGGGCCTGGCCTTCAATGACCAGGTCGTCCCCGTGCTGCCCACGACCGGGGATGA
CGTCGACATGGACCTGGTCGTAACGGAGTCTGAGTCCCTGCGCGGCCTGTACCGCGACTGGGACTTCCTCGATACGTGA

Upstream 100 bases:

>100_bases
GGGATGAGGGAAGCCTGCGGAGGCATGATTTCGGTCCCCACCTGGCTTTTGAGGGTTCAATGGACGCCGGGCACACGGCC
ATGCTGCGGGGGGCTTTTTC

Downstream 100 bases:

>100_bases
AAGTCCTCTTCATGGGGGACGTGGTGGGCCGCCCGGGTCTTCAGGCGGTCCGCACGCTCCTTCCGAGGGTCCGCGCGCAG
CACGGCGTGGACGTGGTGGT

Product: 5,10-methenyltetrahydrofolate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 212; Mature: 211

Protein sequence:

>212_residues
MGAASVSETVVEEAAARKQTLREELTARRKAMTPDLIDTRGLKVQSRFLAAPYYQKARTVALYAPIRGEVPTRDILIAAL
QDGKIVCYPLSHVHGRILSFRAIKSESELEPGRLGVREPTNSADLIAVDQIDLFVVPGLGFTREGKRLGRGGGYYDATLR
AASQRSRRVGLAFNDQVVPVLPTTGDDVDMDLVVTESESLRGLYRDWDFLDT

Sequences:

>Translated_212_residues
MGAASVSETVVEEAAARKQTLREELTARRKAMTPDLIDTRGLKVQSRFLAAPYYQKARTVALYAPIRGEVPTRDILIAAL
QDGKIVCYPLSHVHGRILSFRAIKSESELEPGRLGVREPTNSADLIAVDQIDLFVVPGLGFTREGKRLGRGGGYYDATLR
AASQRSRRVGLAFNDQVVPVLPTTGDDVDMDLVVTESESLRGLYRDWDFLDT
>Mature_211_residues
GAASVSETVVEEAAARKQTLREELTARRKAMTPDLIDTRGLKVQSRFLAAPYYQKARTVALYAPIRGEVPTRDILIAALQ
DGKIVCYPLSHVHGRILSFRAIKSESELEPGRLGVREPTNSADLIAVDQIDLFVVPGLGFTREGKRLGRGGGYYDATLRA
ASQRSRRVGLAFNDQVVPVLPTTGDDVDMDLVVTESESLRGLYRDWDFLDT

Specific function: Unknown

COG id: COG0212

COG function: function code H; 5-formyltetrahydrofolate cyclo-ligase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 5-formyltetrahydrofolate cyclo-ligase family [H]

Homologues:

Organism=Homo sapiens, GI5453746, Length=214, Percent_Identity=29.4392523364486, Blast_Score=93, Evalue=2e-19,
Organism=Escherichia coli, GI1789278, Length=175, Percent_Identity=32.5714285714286, Blast_Score=88, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17510857, Length=168, Percent_Identity=25, Blast_Score=71, Evalue=3e-13,
Organism=Drosophila melanogaster, GI161077430, Length=192, Percent_Identity=25.5208333333333, Blast_Score=69, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002698 [H]

Pfam domain/function: PF01812 5-FTHF_cyc-lig [H]

EC number: NA

Molecular weight: Translated: 23378; Mature: 23247

Theoretical pI: Translated: 7.51; Mature: 7.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
1.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGAASVSETVVEEAAARKQTLREELTARRKAMTPDLIDTRGLKVQSRFLAAPYYQKARTV
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEHHHHHCCCHHHCCCEE
ALYAPIRGEVPTRDILIAALQDGKIVCYPLSHVHGRILSFRAIKSESELEPGRLGVREPT
EEEECCCCCCCCCEEEEEEECCCCEEEEEHHHHHCHHHHEEEECCCCCCCCCCCCCCCCC
NSADLIAVDQIDLFVVPGLGFTREGKRLGRGGGYYDATLRAASQRSRRVGLAFNDQVVPV
CCCCEEEEECEEEEEECCCCCCCCCHHHCCCCCCHHHHHHHHHHHHCEECEEECCCEEEE
LPTTGDDVDMDLVVTESESLRGLYRDWDFLDT
ECCCCCCCCEEEEEECCHHHHHHHHCCCCCCC
>Mature Secondary Structure 
GAASVSETVVEEAAARKQTLREELTARRKAMTPDLIDTRGLKVQSRFLAAPYYQKARTV
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEHHHHHCCCHHHCCCEE
ALYAPIRGEVPTRDILIAALQDGKIVCYPLSHVHGRILSFRAIKSESELEPGRLGVREPT
EEEECCCCCCCCCEEEEEEECCCCEEEEEHHHHHCHHHHEEEECCCCCCCCCCCCCCCCC
NSADLIAVDQIDLFVVPGLGFTREGKRLGRGGGYYDATLRAASQRSRRVGLAFNDQVVPV
CCCCEEEEECEEEEEECCCCCCCCCHHHCCCCCCHHHHHHHHHHHHCEECEEECCCEEEE
LPTTGDDVDMDLVVTESESLRGLYRDWDFLDT
ECCCCCCCCEEEEEECCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]