Click here to switch to the map view.

The map label for this gene is ppnK [H]

Identifier: 108758383

GI number: 108758383

Start: 6676646

End: 6677563

Strand: Reverse

Name: ppnK [H]

Synonym: MXAN_5363

Alternate gene names: 108758383

Gene position: 6677563-6676646 (Counterclockwise)

Preceding gene: 108756988

Following gene: 108758987

Centisome position: 73.06

GC content: 69.61

Gene sequence:

>918_bases
GTGTCGGCCGGCGGGCACCCGGGCATTTCCCATGCGCGCCCGGGGCCCTCCTGGACTACAAGGCGGGGTTGCGTGCAGAC
CCTGGCAATCGTCGCGAAGAGGGACAAGCCCGAGGCGGTAGCGCTCGCGGCTCAAATCCGTGAGCGGTACCCCCACCTGT
CGGTGCTGGCGGACCGCACGCTGGCCCATGAGCTGGGCTGGCCGCGGGTGGATGACCGGGAGCTGGTGACCCGGGCGGAC
CTGATGGTGGTGCTGGGCGGTGACGGCACGCTCATCTACGCGGCGCGCCTGCTCGGCGGCCGCGGGGTTCCGATTCTGGG
CGTCAACCTGGGCAGCCTGGGCTTCATGACGGAAGTCCCGGTGGAAGAGCTGTACCCCATGCTGGAGCAGGTGCTCGCGG
GGCGCTTCCAGGTGGACTCCCGGATGAAGCTCTCCTGCCGCCTGCTGCGCGGGGGCAGGGTGCTCATCGAGGACGAGGTC
CTCAACGACGTGGTCATCAACAAGGGCGCGCTGGCGCGCATCGCCGACCACGAGACGTCCATCGACGGGGTGCCCATCAC
CACCTACAAGTCGGACGGCGTCATCCTGGCTACGCCCACCGGCTCCACGGCGTACTCGCTGTCGGCGGGTGGGCCCATCG
TCCACCCGTCGGTGGACTGCACGGTGCTGTCGCCCATCTGTTCGCACGCCCTCACGCAGCGCTCCATCGTCGTGCCGGCG
GACCGGACCATCCGGGTGACGCTGCGCAGTGAGACGGCGGACACGTACCTGACCATCGACGGGCAGACGGGCCACGGGCT
CCAGGGCGGGGACTGCATCGAGGTGGTGCGCTCGCACAACCGGGTGAACCTGGTGCGCAACCCGAAGGTGGCCTACTTCT
CCATCCTCCGGCAGAAGCTCCACTGGGGCGAGCGCTGA

Upstream 100 bases:

>100_bases
CCGTCGTCTGCTCAAGCAGTACGAGGTGGCCGGCCGGTCCATGAAGCCCCGCGTGGTCTCCCAGGACGACGGCGAGGCGC
TGGAAGCCGCGTCCTGACGT

Downstream 100 bases:

>100_bases
AGGGCGCCGCGCGCCGTGTTCCTCTTCCTGTCGAAGGTGCTCGACCTGTTGCTGGCGCCGCTCTCCTGGGCGCTGCTGCT
GTGGCTGGTGGCCTGGGGGC

Product: putative inorganic polyphosphate/ATP-NAD kinase

Products: NA

Alternate protein names: Poly(P)/ATP NAD kinase [H]

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MSAGGHPGISHARPGPSWTTRRGCVQTLAIVAKRDKPEAVALAAQIRERYPHLSVLADRTLAHELGWPRVDDRELVTRAD
LMVVLGGDGTLIYAARLLGGRGVPILGVNLGSLGFMTEVPVEELYPMLEQVLAGRFQVDSRMKLSCRLLRGGRVLIEDEV
LNDVVINKGALARIADHETSIDGVPITTYKSDGVILATPTGSTAYSLSAGGPIVHPSVDCTVLSPICSHALTQRSIVVPA
DRTIRVTLRSETADTYLTIDGQTGHGLQGGDCIEVVRSHNRVNLVRNPKVAYFSILRQKLHWGER

Sequences:

>Translated_305_residues
MSAGGHPGISHARPGPSWTTRRGCVQTLAIVAKRDKPEAVALAAQIRERYPHLSVLADRTLAHELGWPRVDDRELVTRAD
LMVVLGGDGTLIYAARLLGGRGVPILGVNLGSLGFMTEVPVEELYPMLEQVLAGRFQVDSRMKLSCRLLRGGRVLIEDEV
LNDVVINKGALARIADHETSIDGVPITTYKSDGVILATPTGSTAYSLSAGGPIVHPSVDCTVLSPICSHALTQRSIVVPA
DRTIRVTLRSETADTYLTIDGQTGHGLQGGDCIEVVRSHNRVNLVRNPKVAYFSILRQKLHWGER
>Mature_304_residues
SAGGHPGISHARPGPSWTTRRGCVQTLAIVAKRDKPEAVALAAQIRERYPHLSVLADRTLAHELGWPRVDDRELVTRADL
MVVLGGDGTLIYAARLLGGRGVPILGVNLGSLGFMTEVPVEELYPMLEQVLAGRFQVDSRMKLSCRLLRGGRVLIEDEVL
NDVVINKGALARIADHETSIDGVPITTYKSDGVILATPTGSTAYSLSAGGPIVHPSVDCTVLSPICSHALTQRSIVVPAD
RTIRVTLRSETADTYLTIDGQTGHGLQGGDCIEVVRSHNRVNLVRNPKVAYFSILRQKLHWGER

Specific function: Catalyzes the phosphorylation of NAD to NADP. Utilizes ATP and other nucleoside triphosphates as well as inorganic polyphosphate as a source of phosphorus [H]

COG id: COG0061

COG function: function code G; Predicted sugar kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAD kinase family [H]

Homologues:

Organism=Homo sapiens, GI55743112, Length=266, Percent_Identity=34.9624060150376, Blast_Score=139, Evalue=3e-33,
Organism=Escherichia coli, GI1788968, Length=254, Percent_Identity=34.251968503937, Blast_Score=156, Evalue=2e-39,
Organism=Saccharomyces cerevisiae, GI6320794, Length=242, Percent_Identity=32.2314049586777, Blast_Score=142, Evalue=8e-35,
Organism=Saccharomyces cerevisiae, GI6322509, Length=256, Percent_Identity=32.03125, Blast_Score=137, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6325068, Length=284, Percent_Identity=30.9859154929577, Blast_Score=137, Evalue=2e-33,
Organism=Drosophila melanogaster, GI28573828, Length=253, Percent_Identity=34.3873517786561, Blast_Score=123, Evalue=1e-28,
Organism=Drosophila melanogaster, GI28573832, Length=253, Percent_Identity=34.3873517786561, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI28573830, Length=253, Percent_Identity=34.3873517786561, Blast_Score=122, Evalue=2e-28,
Organism=Drosophila melanogaster, GI28573826, Length=253, Percent_Identity=34.3873517786561, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI161077047, Length=253, Percent_Identity=34.3873517786561, Blast_Score=122, Evalue=3e-28,
Organism=Drosophila melanogaster, GI20129957, Length=278, Percent_Identity=31.294964028777, Blast_Score=117, Evalue=7e-27,
Organism=Drosophila melanogaster, GI281363321, Length=278, Percent_Identity=31.294964028777, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24653422, Length=278, Percent_Identity=31.294964028777, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI281363323, Length=278, Percent_Identity=31.294964028777, Blast_Score=117, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24653424, Length=278, Percent_Identity=31.294964028777, Blast_Score=116, Evalue=2e-26,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016064
- InterPro:   IPR017438
- InterPro:   IPR017437
- InterPro:   IPR002504 [H]

Pfam domain/function: PF01513 NAD_kinase [H]

EC number: =2.7.1.23 [H]

Molecular weight: Translated: 32998; Mature: 32867

Theoretical pI: Translated: 8.49; Mature: 8.49

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAGGHPGISHARPGPSWTTRRGCVQTLAIVAKRDKPEAVALAAQIRERYPHLSVLADRT
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEHHHHH
LAHELGWPRVDDRELVTRADLMVVLGGDGTLIYAARLLGGRGVPILGVNLGSLGFMTEVP
HHHHCCCCCCCCHHHHEEEEEEEEECCCCCEEEEEHHHCCCCCEEEEECCCCCCCEECCC
VEELYPMLEQVLAGRFQVDSRMKLSCRLLRGGRVLIEDEVLNDVVINKGALARIADHETS
HHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCEEEEEHHHHHHHHCCCCCCEEEECCCCC
IDGVPITTYKSDGVILATPTGSTAYSLSAGGPIVHPSVDCTVLSPICSHALTQRSIVVPA
CCCEEEEEECCCCEEEECCCCCCEEEECCCCCEECCCCCCEEHHHHHHHHHHCCEEEECC
DRTIRVTLRSETADTYLTIDGQTGHGLQGGDCIEVVRSHNRVNLVRNPKVAYFSILRQKL
CCEEEEEEECCCCCEEEEEECCCCCCCCCCHHHHHHHCCCCEEEEECCCHHHHHHHHHHH
HWGER
HCCCC
>Mature Secondary Structure 
SAGGHPGISHARPGPSWTTRRGCVQTLAIVAKRDKPEAVALAAQIRERYPHLSVLADRT
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEHHHHH
LAHELGWPRVDDRELVTRADLMVVLGGDGTLIYAARLLGGRGVPILGVNLGSLGFMTEVP
HHHHCCCCCCCCHHHHEEEEEEEEECCCCCEEEEEHHHCCCCCEEEEECCCCCCCEECCC
VEELYPMLEQVLAGRFQVDSRMKLSCRLLRGGRVLIEDEVLNDVVINKGALARIADHETS
HHHHHHHHHHHHCCCCCCCCCCEEEEEEECCCEEEEEHHHHHHHHCCCCCCEEEECCCCC
IDGVPITTYKSDGVILATPTGSTAYSLSAGGPIVHPSVDCTVLSPICSHALTQRSIVVPA
CCCEEEEEECCCCEEEECCCCCCEEEECCCCCEECCCCCCEEHHHHHHHHHHCCEEEECC
DRTIRVTLRSETADTYLTIDGQTGHGLQGGDCIEVVRSHNRVNLVRNPKVAYFSILRQKL
CCEEEEEEECCCCCEEEEEECCCCCCCCCCHHHHHHHCCCCEEEEECCCHHHHHHHHHHH
HWGER
HCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA