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The map label for this gene is nuoN

Identifier: 108758173

GI number: 108758173

Start: 1259280

End: 1260839

Strand: Reverse

Name: nuoN

Synonym: MXAN_1080

Alternate gene names: 108758173

Gene position: 1260839-1259280 (Counterclockwise)

Preceding gene: 108758088

Following gene: 108762843

Centisome position: 13.8

GC content: 68.4

Gene sequence:

>1560_bases
ATGAACCTGCCCAATCTCAGCCTGGCAGACTTCCTCCCGCTGCTGCCCGCCATCATCATGGTGGTGGGCGCCTCCATCCT
GCTGTTGTCGGAGGTGTTCCTCTCCACGACGGCGTCGCGCGCGTACCAGGCGGTGCTCACCGTGGTGACGGCGGTGGCGG
CCGGCGCCATGGCGCTGACGACGATGTTCGAGCCACCCCAGGAGGTGATGCTCGGCTTCGGCGTGATGGACCCCTTCTCC
AGCTTCCTCACCTTCGTGGTGTGCGTGGGCCTGGGGCTGGCGACCCTGAGCTCGGTGAGCTTCCTGCGCAAGCGCGGCGC
GGAGCGCGGTGAGTTCTACGCGCTGATGCTGTTCGCCTCGGCGGGCATGAGCCTGCTTGCGATGTCGAACGAGCTCATCA
CGCTCTTCGTCAACATCGAGGTCCTCTCCCTCTCCACCTACGCGCTGACGTCGTACCTGCGGCGTGGCACGCGGCCGAGC
GAGGCGGGCTTCAAGTACTTCATCCTGGGCGCCTTCTCGTCCGCGGTGCTGCTCTACGGCGCGGCGCTGCTGTACGGCGC
CACCGGCACCACCCACCTGACGGCCATGGCCGGTCCGCTGTCCACCGCCATGTCGTCGCAGCCGGGCCTGGTGTACGCGG
GCATCATCCTGGTGATCACGGGCTTCGCCTTCAAGGTCGCCGCGGTGCCGTTCCACATGTGGACGCCGGACGTCTACGAG
GGCGCGCCGACGCCGGTCACCGCGCTGATGAGCGTGGGCGTGAAGGCGGCCGCCTTCGCGGCGATGGTCCGCGTGTTCTT
CATGGTGGGCAAGGGCGTGGACCCGCAGATGCTGCTGGGCCTGTTCTCCGTGCTGGCCTTCCTCACCATGGTGGCGGGCA
ACCTGCTGGCGATTCCGCAGCGCAACGTGAAGCGCATGCTGGCGTACTCGTCCATTGCCCACGCCGGCTACCTGCTGGTG
GGCGTGGCCGCCCTCTTCGTCACCGGCCCGGGCGAGCAGTTCCGCCTGCTGGGTGCGTCCGCGCTGACGGGTGGCACCCC
GCTGGGCCTGGCCCGCGCGGAGGCGCTGCGCGGCATCCTCTACTACCTGCTGGCGTACACGTTCAGCGCGGTGGGCGCCT
TCGCCATCGTCTCCGTCCTGGAGCGTCGCGAGGACGAGGAGAAGGGCACCGCCTGGGACCTGGAGCGCTTCAGCGGGCTG
GCGCAGCGCAAGCCGGGTTGGGCCTTCGCGATGGCGGCCTTCATGCTGTCGCTGGGTGGCATCCCGCCCACCATCGGATT
CATGAGCAAGCTGCTCATCTTCCAGGCCGCCGTGGATGCGGGCCTCATCGGCCTCACCATCGTCGGCGTGCTCTCCAGCG
CGGTGGGCATCTATTACTACCTGCGCGTGGTGGTCTACATGTTCATGCGGCCGGTGCCGGAGGGCGCGCAGGCGCTCGAG
AAGAGCTGGTCCACCGAACTGGCGCTGGTGCTGTCCACCGCGGCGGTCGTGATTCTGGGCATCATCCCCGGTCCCATCAT
GGGCTGGCTGGAGCAGGCCAGCAGCATCTTCGGCCAGTAG

Upstream 100 bases:

>100_bases
TGCCATCCCGTCAGGTCGTCGCCGCGCCGTCCGCGCCCGTTCCGTTGGCCGCCGCCCCGGCCGTTCCCTCGCCGCGGCAG
TAGCCGCCTGAGCTTCCGAC

Downstream 100 bases:

>100_bases
CCTCCCGCCTCCGCTGTCACACCCCGCCCGCCCCGGCTTCGTGCTCGGGCGGGCGTCGTGTTTTCAGCGCCCGTGAATCA
GGGCGCCGCGTCCACCAGCA

Product: NADH dehydrogenase I subunit N

Products: NA

Alternate protein names: NADH dehydrogenase I subunit N; NDH-1 subunit N

Number of amino acids: Translated: 519; Mature: 519

Protein sequence:

>519_residues
MNLPNLSLADFLPLLPAIIMVVGASILLLSEVFLSTTASRAYQAVLTVVTAVAAGAMALTTMFEPPQEVMLGFGVMDPFS
SFLTFVVCVGLGLATLSSVSFLRKRGAERGEFYALMLFASAGMSLLAMSNELITLFVNIEVLSLSTYALTSYLRRGTRPS
EAGFKYFILGAFSSAVLLYGAALLYGATGTTHLTAMAGPLSTAMSSQPGLVYAGIILVITGFAFKVAAVPFHMWTPDVYE
GAPTPVTALMSVGVKAAAFAAMVRVFFMVGKGVDPQMLLGLFSVLAFLTMVAGNLLAIPQRNVKRMLAYSSIAHAGYLLV
GVAALFVTGPGEQFRLLGASALTGGTPLGLARAEALRGILYYLLAYTFSAVGAFAIVSVLERREDEEKGTAWDLERFSGL
AQRKPGWAFAMAAFMLSLGGIPPTIGFMSKLLIFQAAVDAGLIGLTIVGVLSSAVGIYYYLRVVVYMFMRPVPEGAQALE
KSWSTELALVLSTAAVVILGIIPGPIMGWLEQASSIFGQ

Sequences:

>Translated_519_residues
MNLPNLSLADFLPLLPAIIMVVGASILLLSEVFLSTTASRAYQAVLTVVTAVAAGAMALTTMFEPPQEVMLGFGVMDPFS
SFLTFVVCVGLGLATLSSVSFLRKRGAERGEFYALMLFASAGMSLLAMSNELITLFVNIEVLSLSTYALTSYLRRGTRPS
EAGFKYFILGAFSSAVLLYGAALLYGATGTTHLTAMAGPLSTAMSSQPGLVYAGIILVITGFAFKVAAVPFHMWTPDVYE
GAPTPVTALMSVGVKAAAFAAMVRVFFMVGKGVDPQMLLGLFSVLAFLTMVAGNLLAIPQRNVKRMLAYSSIAHAGYLLV
GVAALFVTGPGEQFRLLGASALTGGTPLGLARAEALRGILYYLLAYTFSAVGAFAIVSVLERREDEEKGTAWDLERFSGL
AQRKPGWAFAMAAFMLSLGGIPPTIGFMSKLLIFQAAVDAGLIGLTIVGVLSSAVGIYYYLRVVVYMFMRPVPEGAQALE
KSWSTELALVLSTAAVVILGIIPGPIMGWLEQASSIFGQ
>Mature_519_residues
MNLPNLSLADFLPLLPAIIMVVGASILLLSEVFLSTTASRAYQAVLTVVTAVAAGAMALTTMFEPPQEVMLGFGVMDPFS
SFLTFVVCVGLGLATLSSVSFLRKRGAERGEFYALMLFASAGMSLLAMSNELITLFVNIEVLSLSTYALTSYLRRGTRPS
EAGFKYFILGAFSSAVLLYGAALLYGATGTTHLTAMAGPLSTAMSSQPGLVYAGIILVITGFAFKVAAVPFHMWTPDVYE
GAPTPVTALMSVGVKAAAFAAMVRVFFMVGKGVDPQMLLGLFSVLAFLTMVAGNLLAIPQRNVKRMLAYSSIAHAGYLLV
GVAALFVTGPGEQFRLLGASALTGGTPLGLARAEALRGILYYLLAYTFSAVGAFAIVSVLERREDEEKGTAWDLERFSGL
AQRKPGWAFAMAAFMLSLGGIPPTIGFMSKLLIFQAAVDAGLIGLTIVGVLSSAVGIYYYLRVVVYMFMRPVPEGAQALE
KSWSTELALVLSTAAVVILGIIPGPIMGWLEQASSIFGQ

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1007

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 2 (chain N)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 2 family

Homologues:

Organism=Escherichia coli, GI145693160, Length=520, Percent_Identity=33.4615384615385, Blast_Score=234, Evalue=1e-62,
Organism=Escherichia coli, GI1788829, Length=376, Percent_Identity=28.9893617021277, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1788831, Length=412, Percent_Identity=25.4854368932039, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1788827, Length=394, Percent_Identity=28.4263959390863, Blast_Score=92, Evalue=6e-20,
Organism=Escherichia coli, GI1788614, Length=460, Percent_Identity=21.304347826087, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI2367154, Length=344, Percent_Identity=25.2906976744186, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NUON_MYXXD (Q1DDD3)

Other databases:

- EMBL:   CP000113
- RefSeq:   YP_629340.1
- STRING:   Q1DDD3
- GeneID:   4101721
- GenomeReviews:   CP000113_GR
- KEGG:   mxa:MXAN_1080
- TIGR:   MXAN_1080
- HOGENOM:   HBG747830
- OMA:   LMFFSEP
- PhylomeDB:   Q1DDD3
- ProtClustDB:   CLSK945022
- BioCyc:   MXAN246197:MXAN_1080-MONOMER
- GO:   GO:0006810
- HAMAP:   MF_00445
- InterPro:   IPR010096
- InterPro:   IPR001750
- TIGRFAMs:   TIGR01770

Pfam domain/function: PF00361 Oxidored_q1

EC number: =1.6.99.5

Molecular weight: Translated: 54860; Mature: 54860

Theoretical pI: Translated: 8.73; Mature: 8.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x13c27fd0)-; HASH(0x149d4f54)-; HASH(0x1501c474)-; HASH(0x13dd8a80)-; HASH(0x151b06d4)-; HASH(0x14b240ec)-; HASH(0x1479c1d4)-; HASH(0x1466a430)-; HASH(0x1300b4a8)-; HASH(0x152e0e2c)-; HASH(0x12420e28)-; HASH(0x15054d78)-; HASH(0x147dac14)-;

Cys/Met content:

0.2 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNLPNLSLADFLPLLPAIIMVVGASILLLSEVFLSTTASRAYQAVLTVVTAVAAGAMALT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TMFEPPQEVMLGFGVMDPFSSFLTFVVCVGLGLATLSSVSFLRKRGAERGEFYALMLFAS
HHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
AGMSLLAMSNELITLFVNIEVLSLSTYALTSYLRRGTRPSEAGFKYFILGAFSSAVLLYG
CCHHHHHHCCCEEEEEEEEEEEEHHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHHHH
AALLYGATGTTHLTAMAGPLSTAMSSQPGLVYAGIILVITGFAFKVAAVPFHMWTPDVYE
HHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCC
GAPTPVTALMSVGVKAAAFAAMVRVFFMVGKGVDPQMLLGLFSVLAFLTMVAGNLLAIPQ
CCCCHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCEEECCH
RNVKRMLAYSSIAHAGYLLVGVAALFVTGPGEQFRLLGASALTGGTPLGLARAEALRGIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEECHHHHCCCCCCHHHHHHHHHHHH
YYLLAYTFSAVGAFAIVSVLERREDEEKGTAWDLERFSGLAQRKPGWAFAMAAFMLSLGG
HHHHHHHHHHHHHHHHHHHHHHHCCHHCCCEECHHHHHHHHHCCCCHHHHHHHHHHHHCC
IPPTIGFMSKLLIFQAAVDAGLIGLTIVGVLSSAVGIYYYLRVVVYMFMRPVPEGAQALE
CCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
KSWSTELALVLSTAAVVILGIIPGPIMGWLEQASSIFGQ
HHHCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCH
>Mature Secondary Structure
MNLPNLSLADFLPLLPAIIMVVGASILLLSEVFLSTTASRAYQAVLTVVTAVAAGAMALT
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TMFEPPQEVMLGFGVMDPFSSFLTFVVCVGLGLATLSSVSFLRKRGAERGEFYALMLFAS
HHCCCHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHH
AGMSLLAMSNELITLFVNIEVLSLSTYALTSYLRRGTRPSEAGFKYFILGAFSSAVLLYG
CCHHHHHHCCCEEEEEEEEEEEEHHHHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHHHH
AALLYGATGTTHLTAMAGPLSTAMSSQPGLVYAGIILVITGFAFKVAAVPFHMWTPDVYE
HHHHHCCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHCC
GAPTPVTALMSVGVKAAAFAAMVRVFFMVGKGVDPQMLLGLFSVLAFLTMVAGNLLAIPQ
CCCCHHHHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCEEECCH
RNVKRMLAYSSIAHAGYLLVGVAALFVTGPGEQFRLLGASALTGGTPLGLARAEALRGIL
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHEEECHHHHCCCCCCHHHHHHHHHHHH
YYLLAYTFSAVGAFAIVSVLERREDEEKGTAWDLERFSGLAQRKPGWAFAMAAFMLSLGG
HHHHHHHHHHHHHHHHHHHHHHHCCHHCCCEECHHHHHHHHHCCCCHHHHHHHHHHHHCC
IPPTIGFMSKLLIFQAAVDAGLIGLTIVGVLSSAVGIYYYLRVVVYMFMRPVPEGAQALE
CCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHH
KSWSTELALVLSTAAVVILGIIPGPIMGWLEQASSIFGQ
HHHCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA