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The map label for this gene is nqo13 [H]

Identifier: 108758088

GI number: 108758088

Start: 1260857

End: 1262590

Strand: Reverse

Name: nqo13 [H]

Synonym: MXAN_1081

Alternate gene names: 108758088

Gene position: 1262590-1260857 (Counterclockwise)

Preceding gene: 108764092

Following gene: 108758173

Centisome position: 13.81

GC content: 67.42

Gene sequence:

>1734_bases
ATGAGCTTCTTCGACAACCACCTGCTCAACCTCGTCGTCTTCCTGCCGCTGGTGTTCGCGGCGCTGGTGGCGCTGCTGCC
TGCCGGCGAGAGCGGCCAGATTCGCACCGTCACGTTCATCGCCATGGTGCTGGACCTGGCGTTCGGGGTCTGGGCCTACA
TGGCGTACGTGCCGGGCGGGCCGGAGTTCCAGCTCGAGTACCGGGCGCGTTGGTTCGACCTGTTCGGCACCAGCTACCAC
ATTGGCGTGGACGGCCTGGCCGTGAGCCTGCTGCTGCTCACCGTCTTCCTGGGGCCCCTGGTGGTGCTGGCGTCCACCAC
GTACATCAAGTTCCGCATCAAGGAATTCCACCTGGCGCTGCTGGTGCTCCAGACAACGATGCTGGGCGCGCTGGTGTCGC
TGGACGTGCTGCTCTTCTACATCTTCTTCGAGGCCATGCTCATCCCCATGTACCTCCTGGTGGGTGTGTGGGGCGCCGAG
GACCGCCAGATGGCGGCGGTGAAGTTCTTCCTCTACACGCTGGCCGGCTCGCTGCTGATGCTGGTGGCCATCATCGCCGT
GTACTTCATCAGCTCGCCGGTGGGTGCCCGCTCGTTCGACTACGCGAGCATCTACAACGGCCTGCTGGACGCCAACCGTC
AGCTCAGCGCATGCACCGCGGGGCCCGCGGGCGCGTGTGACTCACTCACCGGGCTGGCCGCCACGCTGCACACCTGGGGC
CCGTGGCTGTTCGCGGCGTTCGCCATCGCGTTCGCCGTCAAGGTCCCCATGTGGCCGCTGCACACCTGGTTGCCGGACGC
GCACGTGCAGGCGCCAGTGGCCGGCTCCATGATTCTGGCCGGCGTCACCCTGAAGATGGGGACCTTCGGCTTCTGGCGCT
ACGCGATTCCCTTCTTCCCGGTGGCCACGCAGCAGGCGCGGCCCTTCCTTGCCACGCTGGCCGTCATCGGCATCGTGTAC
GGCGCGCTGATGTGCCTGGCGCAGCGGGACATCAAGAAGCTCATCGCGTACTCGTCGGTCAGCCACCTGGGCTACTGCAT
GCTGGGCATCCTGGCGATTACGGCCGAGGGCGCCACGGGCAGCGCGTACCAGATGCTCAACCACGGTGTGTCCACGGGCG
CGCTGTTCCTCCTGTTCGGCTACCTGTACGAGCGGCGCCACTCGCGCCTGATGGCGGACTACGGCGGCATCGCGAAGGTG
ATGCCGGTGTTCACCGCGGCCTTCGTCATCATCACCTTCTCCTCCATCGCGGTGCCGGGCACCAACGGCTTCATCGGTGA
GTTCCTGGTCCTGCTGGGCACCTTCAAGAGCGACCTGGGCGAGGCCGCGGGCAACCCGCACCTGACGGCGGTGTTCGGCG
CCTTCGCCACGCTGGGCGTCATCCTGGGCGCCGCGTACATGCTGTGGATGGTGCAGAAGGTGTTCTTCGGTGGAATCACC
CACCGGGAGAACCAGCACCTGACGGACATGAACCTGCGCGAGGGCCTCACGGTGCTCCCCTTCATCGTCCTGGTCGCTGT
GATGGGTCTGCAGCCGCAGCCCTTCCTGGACCGGCTGGCGCCTTCCACGGACCGCTTCCTGGCCCGCGCCCGCGTGGGCA
CGCCGGGGGCCGAGTTGCAGGAGGACCGACTTCGGGTAGAGGTGATGTCCCTGCCATCCCGTCAGGTCGTCGCCGCGCCG
TCCGCGCCCGTTCCGTTGGCCGCCGCCCCGGCCGTTCCCTCGCCGCGGCAGTAG

Upstream 100 bases:

>100_bases
CGCTCCGCTACGTGCAGTCGGGCGATGCCCAGGCCTACGCCGCTGTGATGGCCATCGCCCTGTTGGGCGGGATGGCCTAC
GCCCTCATCCAGGTGATGCA

Downstream 100 bases:

>100_bases
CCGCCTGAGCTTCCGACATGAACCTGCCCAATCTCAGCCTGGCAGACTTCCTCCCGCTGCTGCCCGCCATCATCATGGTG
GTGGGCGCCTCCATCCTGCT

Product: NADH dehydrogenase I subunit M

Products: NA

Alternate protein names: NADH dehydrogenase I, chain 13; NDH-1, chain 13 [H]

Number of amino acids: Translated: 577; Mature: 576

Protein sequence:

>577_residues
MSFFDNHLLNLVVFLPLVFAALVALLPAGESGQIRTVTFIAMVLDLAFGVWAYMAYVPGGPEFQLEYRARWFDLFGTSYH
IGVDGLAVSLLLLTVFLGPLVVLASTTYIKFRIKEFHLALLVLQTTMLGALVSLDVLLFYIFFEAMLIPMYLLVGVWGAE
DRQMAAVKFFLYTLAGSLLMLVAIIAVYFISSPVGARSFDYASIYNGLLDANRQLSACTAGPAGACDSLTGLAATLHTWG
PWLFAAFAIAFAVKVPMWPLHTWLPDAHVQAPVAGSMILAGVTLKMGTFGFWRYAIPFFPVATQQARPFLATLAVIGIVY
GALMCLAQRDIKKLIAYSSVSHLGYCMLGILAITAEGATGSAYQMLNHGVSTGALFLLFGYLYERRHSRLMADYGGIAKV
MPVFTAAFVIITFSSIAVPGTNGFIGEFLVLLGTFKSDLGEAAGNPHLTAVFGAFATLGVILGAAYMLWMVQKVFFGGIT
HRENQHLTDMNLREGLTVLPFIVLVAVMGLQPQPFLDRLAPSTDRFLARARVGTPGAELQEDRLRVEVMSLPSRQVVAAP
SAPVPLAAAPAVPSPRQ

Sequences:

>Translated_577_residues
MSFFDNHLLNLVVFLPLVFAALVALLPAGESGQIRTVTFIAMVLDLAFGVWAYMAYVPGGPEFQLEYRARWFDLFGTSYH
IGVDGLAVSLLLLTVFLGPLVVLASTTYIKFRIKEFHLALLVLQTTMLGALVSLDVLLFYIFFEAMLIPMYLLVGVWGAE
DRQMAAVKFFLYTLAGSLLMLVAIIAVYFISSPVGARSFDYASIYNGLLDANRQLSACTAGPAGACDSLTGLAATLHTWG
PWLFAAFAIAFAVKVPMWPLHTWLPDAHVQAPVAGSMILAGVTLKMGTFGFWRYAIPFFPVATQQARPFLATLAVIGIVY
GALMCLAQRDIKKLIAYSSVSHLGYCMLGILAITAEGATGSAYQMLNHGVSTGALFLLFGYLYERRHSRLMADYGGIAKV
MPVFTAAFVIITFSSIAVPGTNGFIGEFLVLLGTFKSDLGEAAGNPHLTAVFGAFATLGVILGAAYMLWMVQKVFFGGIT
HRENQHLTDMNLREGLTVLPFIVLVAVMGLQPQPFLDRLAPSTDRFLARARVGTPGAELQEDRLRVEVMSLPSRQVVAAP
SAPVPLAAAPAVPSPRQ
>Mature_576_residues
SFFDNHLLNLVVFLPLVFAALVALLPAGESGQIRTVTFIAMVLDLAFGVWAYMAYVPGGPEFQLEYRARWFDLFGTSYHI
GVDGLAVSLLLLTVFLGPLVVLASTTYIKFRIKEFHLALLVLQTTMLGALVSLDVLLFYIFFEAMLIPMYLLVGVWGAED
RQMAAVKFFLYTLAGSLLMLVAIIAVYFISSPVGARSFDYASIYNGLLDANRQLSACTAGPAGACDSLTGLAATLHTWGP
WLFAAFAIAFAVKVPMWPLHTWLPDAHVQAPVAGSMILAGVTLKMGTFGFWRYAIPFFPVATQQARPFLATLAVIGIVYG
ALMCLAQRDIKKLIAYSSVSHLGYCMLGILAITAEGATGSAYQMLNHGVSTGALFLLFGYLYERRHSRLMADYGGIAKVM
PVFTAAFVIITFSSIAVPGTNGFIGEFLVLLGTFKSDLGEAAGNPHLTAVFGAFATLGVILGAAYMLWMVQKVFFGGITH
RENQHLTDMNLREGLTVLPFIVLVAVMGLQPQPFLDRLAPSTDRFLARARVGTPGAELQEDRLRVEVMSLPSRQVVAAPS
APVPLAAAPAVPSPRQ

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1008

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 4 (chain M)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 4 family [H]

Homologues:

Organism=Homo sapiens, GI251831116, Length=377, Percent_Identity=32.8912466843501, Blast_Score=183, Evalue=4e-46,
Organism=Escherichia coli, GI1788613, Length=496, Percent_Identity=36.491935483871, Blast_Score=288, Evalue=5e-79,
Organism=Escherichia coli, GI1788827, Length=333, Percent_Identity=30.03003003003, Blast_Score=108, Evalue=7e-25,
Organism=Escherichia coli, GI145693160, Length=297, Percent_Identity=30.976430976431, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1788831, Length=374, Percent_Identity=24.331550802139, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1788829, Length=359, Percent_Identity=27.8551532033426, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI2367154, Length=285, Percent_Identity=25.9649122807018, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1788614, Length=518, Percent_Identity=22.972972972973, Blast_Score=68, Evalue=2e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010227
- InterPro:   IPR001750
- InterPro:   IPR003918
- InterPro:   IPR000260 [H]

Pfam domain/function: PF00361 Oxidored_q1; PF01059 Oxidored_q5_N [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 62452; Mature: 62320

Theoretical pI: Translated: 8.01; Mature: 8.01

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFFDNHLLNLVVFLPLVFAALVALLPAGESGQIRTVTFIAMVLDLAFGVWAYMAYVPGG
CCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC
PEFQLEYRARWFDLFGTSYHIGVDGLAVSLLLLTVFLGPLVVLASTTYIKFRIKEFHLAL
CCEEEHHHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHHHHHHCCHHEEEEHHHHHHHH
LVLQTTMLGALVSLDVLLFYIFFEAMLIPMYLLVGVWGAEDRQMAAVKFFLYTLAGSLLM
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHH
LVAIIAVYFISSPVGARSFDYASIYNGLLDANRQLSACTAGPAGACDSLTGLAATLHTWG
HHHHHHHHHHCCCCCCCCCCHHHHHHHHHHCCCCCHHCCCCCCCCHHHHHHHHHHHHHHH
PWLFAAFAIAFAVKVPMWPLHTWLPDAHVQAPVAGSMILAGVTLKMGTFGFWRYAIPFFP
HHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHCCCCC
VATQQARPFLATLAVIGIVYGALMCLAQRDIKKLIAYSSVSHLGYCMLGILAITAEGATG
CCCHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCC
SAYQMLNHGVSTGALFLLFGYLYERRHSRLMADYGGIAKVMPVFTAAFVIITFSSIAVPG
HHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCC
TNGFIGEFLVLLGTFKSDLGEAAGNPHLTAVFGAFATLGVILGAAYMLWMVQKVFFGGIT
CCCHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCC
HRENQHLTDMNLREGLTVLPFIVLVAVMGLQPQPFLDRLAPSTDRFLARARVGTPGAELQ
CCCCCCCCCCCHHCCCHHHHHHHHHHHHCCCCCCHHHHHCCCHHHHHHHHCCCCCCCHHH
EDRLRVEVMSLPSRQVVAAPSAPVPLAAAPAVPSPRQ
HHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
SFFDNHLLNLVVFLPLVFAALVALLPAGESGQIRTVTFIAMVLDLAFGVWAYMAYVPGG
CCHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCC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HHHHHHHHCCCCCCCEEECCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8422400 [H]