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The map label for this gene is nuoN [H]

Identifier: 108563642

GI number: 108563642

Start: 1278920

End: 1280392

Strand: Direct

Name: nuoN [H]

Synonym: HPAG1_1217

Alternate gene names: 108563642

Gene position: 1278920-1280392 (Clockwise)

Preceding gene: 108563641

Following gene: 108563643

Centisome position: 80.11

GC content: 42.5

Gene sequence:

>1473_bases
ATGCTAATAGATAGTCTCCACATCTCTTTTGACAGCTTTAATTTTGAGAGCGTTTTACCCATGCTGGTGTTGGTGTGTGG
GGGGATTTTCACGCTCTTAATCAACGCTTTCACTTCCAGGTTTTCACGCAATTTGAATGTGTTTTTATGCATGCTTTTTT
TGGTTTTGGATTTTTTGGTGGTTTTAGGATTAGAAGAGCAAGAAAACGCCTTTTTTGGGTTTTTGAGCTTGGATACCCTC
TCGCTCATCTCTCAAAGCATTGTCTTGATTTCAGCCTTTTTTCTCATTTTCTTAGCCCTTTCAAAAGAACGCTTCAACGA
ATTTCAAACCGCTGAATTTTATTCCTTATACTTGTTTATTGTTGCTGGCTTTCAGTTCATGGTTTCAAGCAACCATTTAT
TGTTAATCCTTATTGGGTTAGAAACAGCGTCCTTACCCCTTTGCGTGTTAATGGCGTTGAGCGATAAACGCTACGGCTTA
GAAGCAGGGATCAAATATTTCACTATGGGGGCGATGGCGAGTGCGTTTTTTGCTATGGGGGCTATGGCTTTTTACCTGCT
CACAGGGAGCTTGAATCTTGAAGTCATTACCCTATACTTACACACTGAAGGTATCACAAACCCCATGCTCTTTGCGATGG
GCGCTATTTTTTTGATTGGAGCGATTGGCTTTAAGGTTTCTTTAGTGCCTTTCCATACTTGGATGCCTGATGTGTATGAG
GGCAATAACCCGGTCTTTGCAAGCTATATTTCCATTGTGCCTAAAATCGCTGGCTTTGTGGTAGCGACTCGCCTTTTTGG
GGCGTTTATAGACACTCGCATCGCTTGGGTAGAAGACATTTTTTACGCCCTCATTCTTATGACTATCACCATCCCTAATT
TCATTGCTTTATGGCAAGAAGATGTCAAAAGAATGCTCGCTTACAGCTCCATTTCGCATTCTGGGTTCGCTTTAGCATGC
GTGTTTATCCACACTGAAGATAGCCAACAAGCGATGTTTGTTTATTGGTTCATGTTCGCATTCACTTATATTGGGGCTTT
TGGCCTTTTATGGCTCTTAAAAAGCCGGGAAAAAACATGGGATGAACGCTACGATCACCCCTATTCTAAATTCAACGGCC
TTATCAAAACCCACCCTTTAGTGGCGATCTTGGGCGCTATTTTTGTTTTTGGGCTTGCAGGGATCCCGCCTTTTAGCGTG
TTTTGGGGGAAATTTTTAGCCGTTGAAAGCGCTTTAGAGAGCAATCACATTCTTTTAGCGGTGGTGATGTTAGCTAATAG
CGCGGTGGCTGCGTTTTATTATTTCCGTTGGCTCGTGGCGATGTTTTTCAATAAGCCCTTACAAAGCTACGCTCAAAGCG
ATATTTACACCCAAAACGCTACCATGCCCATTTATGCGGTCATTATTGCCATGGCGTTAGCGTGCTTGTTCTCTGTTTTT
ATGATGCGAGGGCTTTTAGAATTTGTGGCTTAA

Upstream 100 bases:

>100_bases
AAACCGATTGAGCAAGGCTCTAAGCAGCTTTTAGAGGTGATAGAAATCCGCTCGCTCCCTTTTTTAGGTTCATTGGATAC
TAAGATAAAAGAGGTCTCTT

Downstream 100 bases:

>100_bases
GTCAAAAATCTTTCTTTTAATGGGCTTATTCTCCCATTCGCTCAACGCCTTAAGCCTCACGCTCACGCAAGGCAAGGAAG
GGGGGGAAGATTTTTCTGTT

Product: NADH dehydrogenase subunit N

Products: NA

Alternate protein names: NADH dehydrogenase I subunit N; NDH-1 subunit N [H]

Number of amino acids: Translated: 490; Mature: 490

Protein sequence:

>490_residues
MLIDSLHISFDSFNFESVLPMLVLVCGGIFTLLINAFTSRFSRNLNVFLCMLFLVLDFLVVLGLEEQENAFFGFLSLDTL
SLISQSIVLISAFFLIFLALSKERFNEFQTAEFYSLYLFIVAGFQFMVSSNHLLLILIGLETASLPLCVLMALSDKRYGL
EAGIKYFTMGAMASAFFAMGAMAFYLLTGSLNLEVITLYLHTEGITNPMLFAMGAIFLIGAIGFKVSLVPFHTWMPDVYE
GNNPVFASYISIVPKIAGFVVATRLFGAFIDTRIAWVEDIFYALILMTITIPNFIALWQEDVKRMLAYSSISHSGFALAC
VFIHTEDSQQAMFVYWFMFAFTYIGAFGLLWLLKSREKTWDERYDHPYSKFNGLIKTHPLVAILGAIFVFGLAGIPPFSV
FWGKFLAVESALESNHILLAVVMLANSAVAAFYYFRWLVAMFFNKPLQSYAQSDIYTQNATMPIYAVIIAMALACLFSVF
MMRGLLEFVA

Sequences:

>Translated_490_residues
MLIDSLHISFDSFNFESVLPMLVLVCGGIFTLLINAFTSRFSRNLNVFLCMLFLVLDFLVVLGLEEQENAFFGFLSLDTL
SLISQSIVLISAFFLIFLALSKERFNEFQTAEFYSLYLFIVAGFQFMVSSNHLLLILIGLETASLPLCVLMALSDKRYGL
EAGIKYFTMGAMASAFFAMGAMAFYLLTGSLNLEVITLYLHTEGITNPMLFAMGAIFLIGAIGFKVSLVPFHTWMPDVYE
GNNPVFASYISIVPKIAGFVVATRLFGAFIDTRIAWVEDIFYALILMTITIPNFIALWQEDVKRMLAYSSISHSGFALAC
VFIHTEDSQQAMFVYWFMFAFTYIGAFGLLWLLKSREKTWDERYDHPYSKFNGLIKTHPLVAILGAIFVFGLAGIPPFSV
FWGKFLAVESALESNHILLAVVMLANSAVAAFYYFRWLVAMFFNKPLQSYAQSDIYTQNATMPIYAVIIAMALACLFSVF
MMRGLLEFVA
>Mature_490_residues
MLIDSLHISFDSFNFESVLPMLVLVCGGIFTLLINAFTSRFSRNLNVFLCMLFLVLDFLVVLGLEEQENAFFGFLSLDTL
SLISQSIVLISAFFLIFLALSKERFNEFQTAEFYSLYLFIVAGFQFMVSSNHLLLILIGLETASLPLCVLMALSDKRYGL
EAGIKYFTMGAMASAFFAMGAMAFYLLTGSLNLEVITLYLHTEGITNPMLFAMGAIFLIGAIGFKVSLVPFHTWMPDVYE
GNNPVFASYISIVPKIAGFVVATRLFGAFIDTRIAWVEDIFYALILMTITIPNFIALWQEDVKRMLAYSSISHSGFALAC
VFIHTEDSQQAMFVYWFMFAFTYIGAFGLLWLLKSREKTWDERYDHPYSKFNGLIKTHPLVAILGAIFVFGLAGIPPFSV
FWGKFLAVESALESNHILLAVVMLANSAVAAFYYFRWLVAMFFNKPLQSYAQSDIYTQNATMPIYAVIIAMALACLFSVF
MMRGLLEFVA

Specific function: NDH-1 shuttles electrons from NADH, via FMN and iron- sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocat

COG id: COG1007

COG function: function code C; NADH:ubiquinone oxidoreductase subunit 2 (chain N)

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the complex I subunit 2 family [H]

Homologues:

Organism=Escherichia coli, GI145693160, Length=352, Percent_Identity=33.5227272727273, Blast_Score=157, Evalue=1e-39,
Organism=Escherichia coli, GI1788831, Length=359, Percent_Identity=23.3983286908078, Blast_Score=85, Evalue=1e-17,
Organism=Escherichia coli, GI1788614, Length=400, Percent_Identity=27.25, Blast_Score=78, Evalue=1e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010096
- InterPro:   IPR001750 [H]

Pfam domain/function: PF00361 Oxidored_q1 [H]

EC number: =1.6.99.5 [H]

Molecular weight: Translated: 55128; Mature: 55128

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.5 %Met     (Translated Protein)
5.5 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.5 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIDSLHISFDSFNFESVLPMLVLVCGGIFTLLINAFTSRFSRNLNVFLCMLFLVLDFLV
CCEECEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
VLGLEEQENAFFGFLSLDTLSLISQSIVLISAFFLIFLALSKERFNEFQTAEFYSLYLFI
HHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAGFQFMVSSNHLLLILIGLETASLPLCVLMALSDKRYGLEAGIKYFTMGAMASAFFAMG
HHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
AMAFYLLTGSLNLEVITLYLHTEGITNPMLFAMGAIFLIGAIGFKVSLVPFHTWMPDVYE
HHHHHHHHCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHEEEEEEHHHCCCCCCC
GNNPVFASYISIVPKIAGFVVATRLFGAFIDTRIAWVEDIFYALILMTITIPNFIALWQE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DVKRMLAYSSISHSGFALACVFIHTEDSQQAMFVYWFMFAFTYIGAFGLLWLLKSREKTW
HHHHHHHHHCCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DERYDHPYSKFNGLIKTHPLVAILGAIFVFGLAGIPPFSVFWGKFLAVESALESNHILLA
HHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHH
VVMLANSAVAAFYYFRWLVAMFFNKPLQSYAQSDIYTQNATMPIYAVIIAMALACLFSVF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
MMRGLLEFVA
HHHHHHHHHC
>Mature Secondary Structure
MLIDSLHISFDSFNFESVLPMLVLVCGGIFTLLINAFTSRFSRNLNVFLCMLFLVLDFLV
CCEECEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
VLGLEEQENAFFGFLSLDTLSLISQSIVLISAFFLIFLALSKERFNEFQTAEFYSLYLFI
HHCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VAGFQFMVSSNHLLLILIGLETASLPLCVLMALSDKRYGLEAGIKYFTMGAMASAFFAMG
HHHHHHHCCCCCEEEEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHH
AMAFYLLTGSLNLEVITLYLHTEGITNPMLFAMGAIFLIGAIGFKVSLVPFHTWMPDVYE
HHHHHHHHCCCCEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHEEEEEEHHHCCCCCCC
GNNPVFASYISIVPKIAGFVVATRLFGAFIDTRIAWVEDIFYALILMTITIPNFIALWQE
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DVKRMLAYSSISHSGFALACVFIHTEDSQQAMFVYWFMFAFTYIGAFGLLWLLKSREKTW
HHHHHHHHHCCCCCCEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
DERYDHPYSKFNGLIKTHPLVAILGAIFVFGLAGIPPFSVFWGKFLAVESALESNHILLA
HHHCCCCHHHHCCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCCHHHH
VVMLANSAVAAFYYFRWLVAMFFNKPLQSYAQSDIYTQNATMPIYAVIIAMALACLFSVF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
MMRGLLEFVA
HHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA