Click here to switch to the map view.

The map label for this gene is alr [H]

Identifier: 108563349

GI number: 108563349

Start: 967351

End: 968484

Strand: Reverse

Name: alr [H]

Synonym: HPAG1_0924

Alternate gene names: 108563349

Gene position: 968484-967351 (Counterclockwise)

Preceding gene: 108563350

Following gene: 108563348

Centisome position: 60.67

GC content: 41.27

Gene sequence:

>1134_bases
ATGTTAAAAAGGGCGAGTTTTGTAGAAGTGAATAGCGCTTCTTTAAGGCATAATTTTAGCGCAGTCAAAAGCATTGTCCC
TAAAGACGCCCACATCATGGCGGTTGTTAAGGCAAACGCTTATGGGGCAGGCGCCATAAAAGCGAGCGAAATTTTCTTGC
AAGAAGGGGCTAATTATTTAGGGGTAGCGGCATTAGATGAAGCCTTAGAGTTGCGCTCTCACTTCCCTAAAACCCCCATT
TTGATTTTAGGCTATAGCCCTAATGCTAACGCTTCCATGCTGATTGATAACGATTTGAGCGCTATGGTTTTTAGCCTTGA
ACAAGCGGAAGTTTTTTCTCAAATGGCTTTAAAATCTCAAAAACGCTTAAAAGTGCATCTCAAAATTGATACCGGCATGC
ACCGCTTGGGCTTAGAACCTAATTTTAAAAGCATAGAAACCATTAAAAAAATCCGCGCTTTAAAGGGCTTGGAAATAGAG
GGGATATTCACGCATTTAAGCAACGCTGATGCTAAGATTAAAACCCATGCTAAAAACCAAATGAAAGCCTTTAACGCTTT
TTTAGAGCAGCTTTTAGATCAAAAAATAGAGTTTCAATACCGCCATGCCTATAATTCCGCCGGCATCCTTTCTTTGTGCA
ACGGGAATGAAAATCGTTTGTTAAACCTCTATCGCCCAGGCATCATGCTCTATGGTTTTTACCCCTCTAATGGAATGAAA
GAATCATGCCCAACCATCTTAAAAAATGTTATCAGTTTGAAAGCGCAAATCGTTCAAATCAGAAGCGTTAAAAAAGGCGA
ATTTATTGGCTATGGCGAGCATTTTTATACCAATGAAGAGACTTTAGTGGGTGTTTTAGCTCTAGGGTATGCAGACGGGT
TAATGCGCGCTTTAGGCAATCGCATTCAAGTAGCGATCAATAACCAATTAGCCCCCCTGATTGGCAAGGTGTGCATGGAT
CAGTGCTTTGTCAAACTCAATGATATTCAAGCCAAAGAGGGCGATGAGGTCATTTTGTTTGGGGATAAAAGCGCTAGAGC
TAATGACGCAAGCGAAATCGCTGCACTTTTAAACACCATTGCTTATGAAACTATCAGCACCCTATCCAAACGCTTGGAGC
GCGTCTATATTTAA

Upstream 100 bases:

>100_bases
TATGGCTATCCCTAATTTAATCGCTTTGATTTTATTGCATAAAGTGGTTTCTTCTGAAACTCGTTGGTATTTTAGCAAGC
ATTCTAACAAGTAAGATGGC

Downstream 100 bases:

>100_bases
AATCAAACCATGCAAAATTTTTATTTTGCGCTAGAATGCGCGAAAAATAATGATTAGGATTGATTAAAAAATGAAAAAAG
TTTTATTTTTATTAGTAATA

Product: alanine racemase, biosynthetic

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 377; Mature: 377

Protein sequence:

>377_residues
MLKRASFVEVNSASLRHNFSAVKSIVPKDAHIMAVVKANAYGAGAIKASEIFLQEGANYLGVAALDEALELRSHFPKTPI
LILGYSPNANASMLIDNDLSAMVFSLEQAEVFSQMALKSQKRLKVHLKIDTGMHRLGLEPNFKSIETIKKIRALKGLEIE
GIFTHLSNADAKIKTHAKNQMKAFNAFLEQLLDQKIEFQYRHAYNSAGILSLCNGNENRLLNLYRPGIMLYGFYPSNGMK
ESCPTILKNVISLKAQIVQIRSVKKGEFIGYGEHFYTNEETLVGVLALGYADGLMRALGNRIQVAINNQLAPLIGKVCMD
QCFVKLNDIQAKEGDEVILFGDKSARANDASEIAALLNTIAYETISTLSKRLERVYI

Sequences:

>Translated_377_residues
MLKRASFVEVNSASLRHNFSAVKSIVPKDAHIMAVVKANAYGAGAIKASEIFLQEGANYLGVAALDEALELRSHFPKTPI
LILGYSPNANASMLIDNDLSAMVFSLEQAEVFSQMALKSQKRLKVHLKIDTGMHRLGLEPNFKSIETIKKIRALKGLEIE
GIFTHLSNADAKIKTHAKNQMKAFNAFLEQLLDQKIEFQYRHAYNSAGILSLCNGNENRLLNLYRPGIMLYGFYPSNGMK
ESCPTILKNVISLKAQIVQIRSVKKGEFIGYGEHFYTNEETLVGVLALGYADGLMRALGNRIQVAINNQLAPLIGKVCMD
QCFVKLNDIQAKEGDEVILFGDKSARANDASEIAALLNTIAYETISTLSKRLERVYI
>Mature_377_residues
MLKRASFVEVNSASLRHNFSAVKSIVPKDAHIMAVVKANAYGAGAIKASEIFLQEGANYLGVAALDEALELRSHFPKTPI
LILGYSPNANASMLIDNDLSAMVFSLEQAEVFSQMALKSQKRLKVHLKIDTGMHRLGLEPNFKSIETIKKIRALKGLEIE
GIFTHLSNADAKIKTHAKNQMKAFNAFLEQLLDQKIEFQYRHAYNSAGILSLCNGNENRLLNLYRPGIMLYGFYPSNGMK
ESCPTILKNVISLKAQIVQIRSVKKGEFIGYGEHFYTNEETLVGVLALGYADGLMRALGNRIQVAINNQLAPLIGKVCMD
QCFVKLNDIQAKEGDEVILFGDKSARANDASEIAALLNTIAYETISTLSKRLERVYI

Specific function: Provides the D-alanine required for cell wall biosynthesis [H]

COG id: COG0787

COG function: function code M; Alanine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the alanine racemase family [H]

Homologues:

Organism=Escherichia coli, GI1790487, Length=385, Percent_Identity=31.4285714285714, Blast_Score=169, Evalue=3e-43,
Organism=Escherichia coli, GI1787439, Length=372, Percent_Identity=29.3010752688172, Blast_Score=132, Evalue=5e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000821
- InterPro:   IPR009006
- InterPro:   IPR011079
- InterPro:   IPR001608
- InterPro:   IPR020622 [H]

Pfam domain/function: PF00842 Ala_racemase_C; PF01168 Ala_racemase_N [H]

EC number: =5.1.1.1 [H]

Molecular weight: Translated: 41731; Mature: 41731

Theoretical pI: Translated: 9.31; Mature: 9.31

Prosite motif: PS00395 ALANINE_RACEMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKRASFVEVNSASLRHNFSAVKSIVPKDAHIMAVVKANAYGAGAIKASEIFLQEGANYL
CCCCCCEEEECCHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCHHHHHHHHCCCCEE
GVAALDEALELRSHFPKTPILILGYSPNANASMLIDNDLSAMVFSLEQAEVFSQMALKSQ
EHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCC
KRLKVHLKIDTGMHRLGLEPNFKSIETIKKIRALKGLEIEGIFTHLSNADAKIKTHAKNQ
CEEEEEEEEECCHHHCCCCCCHHHHHHHHHHHHHCCCCEEEHHHHHCCCCCEEEHHHHHH
MKAFNAFLEQLLDQKIEFQYRHAYNSAGILSLCNGNENRLLNLYRPGIMLYGFYPSNGMK
HHHHHHHHHHHHHHHHCCHHHHHCCCCCEEEEECCCCCCEEEEECCCEEEEEEECCCCCC
ESCPTILKNVISLKAQIVQIRSVKKGEFIGYGEHFYTNEETLVGVLALGYADGLMRALGN
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCEECCCHHHHHHHHHHHHHHHHHHCCC
RIQVAINNQLAPLIGKVCMDQCFVKLNDIQAKEGDEVILFGDKSARANDASEIAALLNTI
EEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHH
AYETISTLSKRLERVYI
HHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLKRASFVEVNSASLRHNFSAVKSIVPKDAHIMAVVKANAYGAGAIKASEIFLQEGANYL
CCCCCCEEEECCHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCCHHHHHHHHCCCCEE
GVAALDEALELRSHFPKTPILILGYSPNANASMLIDNDLSAMVFSLEQAEVFSQMALKSQ
EHHHHHHHHHHHHHCCCCCEEEEEECCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCC
KRLKVHLKIDTGMHRLGLEPNFKSIETIKKIRALKGLEIEGIFTHLSNADAKIKTHAKNQ
CEEEEEEEEECCHHHCCCCCCHHHHHHHHHHHHHCCCCEEEHHHHHCCCCCEEEHHHHHH
MKAFNAFLEQLLDQKIEFQYRHAYNSAGILSLCNGNENRLLNLYRPGIMLYGFYPSNGMK
HHHHHHHHHHHHHHHHCCHHHHHCCCCCEEEEECCCCCCEEEEECCCEEEEEEECCCCCC
ESCPTILKNVISLKAQIVQIRSVKKGEFIGYGEHFYTNEETLVGVLALGYADGLMRALGN
HHHHHHHHHHHHHHHHHHHHHCCCCCCEEECCCCEECCCHHHHHHHHHHHHHHHHHHCCC
RIQVAINNQLAPLIGKVCMDQCFVKLNDIQAKEGDEVILFGDKSARANDASEIAALLNTI
EEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCCCCHHHHHHHHHHH
AYETISTLSKRLERVYI
HHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA