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The map label for this gene is coaE [H]

Identifier: 108563242

GI number: 108563242

Start: 851680

End: 852270

Strand: Reverse

Name: coaE [H]

Synonym: HPAG1_0817

Alternate gene names: 108563242

Gene position: 852270-851680 (Counterclockwise)

Preceding gene: 108563243

Following gene: 108563241

Centisome position: 53.39

GC content: 38.41

Gene sequence:

>591_bases
ATGGTTTTAAAAAACGCTATCGCTCTGACAGGGGGGATAGGCACCGGTAAAAGCACCACCATTAAAATATTAGAATCGCA
AGGCTATGAGATTTTAGATGCGGATAAGATCGCTCACCAATTATTGCAAGAGTACCGGTTTAAAATCGCCCAACATTTTG
GATCAGAGATTTTAGAAAAAGATATTTTGAATCGCAAAAAGCTTGGCGCGATCGTGTTTCAAAAGGCTAATGAGTTAAAA
TGGCTAGAGGATTTTTTACACCCCTTAATCCGTGAACGCATGCTTAAAAAAGCCTATGAATTAGAAAAGAATCATCAAGC
GTATTTTTTAGACATCCCTTTGTTTTTTGAAGTGGGGGGTAAAAAACGCTATCCTGTGAGTAAAGTGGTTTTAATCTATG
CGCCCAGGGCCTTACAAATTGAGCGCCTTTTAGAGCGAGACAAACTCAAAGAAGCTGAAATCTTGCAACGCTTAGCTTGT
CAAATGGATATAGAGCAAAAACGCGCCATGAGCGATTATATTATAGACAACAGCTCCAGTTTAAAAGATTTGAATAAGCA
GGTTGAACGCTTTTTAAAAACGCTCTTATAA

Upstream 100 bases:

>100_bases
CTAACAAGCATGAGATACTATAACGAAGACATTCACAGGGCTGCATTCGCTTTGCCTAAAAATTTACAAGAAGTCTTTAA
AGACAATATCAAATCTTAAA

Downstream 100 bases:

>100_bases
GCTCGTTTTATCTCTAAGCATGTTAAACTACCATTAAATTTTTTAATAAGGCTAAAAACATGATCACTTTAAAACAAGCC
CTTTCTTTATCCCAAGATGA

Product: dephospho-CoA kinase

Products: NA

Alternate protein names: Dephosphocoenzyme A kinase [H]

Number of amino acids: Translated: 196; Mature: 196

Protein sequence:

>196_residues
MVLKNAIALTGGIGTGKSTTIKILESQGYEILDADKIAHQLLQEYRFKIAQHFGSEILEKDILNRKKLGAIVFQKANELK
WLEDFLHPLIRERMLKKAYELEKNHQAYFLDIPLFFEVGGKKRYPVSKVVLIYAPRALQIERLLERDKLKEAEILQRLAC
QMDIEQKRAMSDYIIDNSSSLKDLNKQVERFLKTLL

Sequences:

>Translated_196_residues
MVLKNAIALTGGIGTGKSTTIKILESQGYEILDADKIAHQLLQEYRFKIAQHFGSEILEKDILNRKKLGAIVFQKANELK
WLEDFLHPLIRERMLKKAYELEKNHQAYFLDIPLFFEVGGKKRYPVSKVVLIYAPRALQIERLLERDKLKEAEILQRLAC
QMDIEQKRAMSDYIIDNSSSLKDLNKQVERFLKTLL
>Mature_196_residues
MVLKNAIALTGGIGTGKSTTIKILESQGYEILDADKIAHQLLQEYRFKIAQHFGSEILEKDILNRKKLGAIVFQKANELK
WLEDFLHPLIRERMLKKAYELEKNHQAYFLDIPLFFEVGGKKRYPVSKVVLIYAPRALQIERLLERDKLKEAEILQRLAC
QMDIEQKRAMSDYIIDNSSSLKDLNKQVERFLKTLL

Specific function: Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A [H]

COG id: COG0237

COG function: function code H; Dephospho-CoA kinase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DPCK (dephospho-CoA kinase) domain [H]

Homologues:

Organism=Homo sapiens, GI191252797, Length=187, Percent_Identity=31.0160427807487, Blast_Score=103, Evalue=8e-23,
Organism=Homo sapiens, GI191252795, Length=187, Percent_Identity=31.0160427807487, Blast_Score=103, Evalue=8e-23,
Organism=Homo sapiens, GI110227607, Length=193, Percent_Identity=31.0880829015544, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI110227605, Length=193, Percent_Identity=31.0880829015544, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI110227603, Length=193, Percent_Identity=31.0880829015544, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI110227601, Length=193, Percent_Identity=31.0880829015544, Blast_Score=76, Evalue=2e-14,
Organism=Homo sapiens, GI205277394, Length=193, Percent_Identity=31.0880829015544, Blast_Score=76, Evalue=2e-14,
Organism=Escherichia coli, GI1786292, Length=189, Percent_Identity=30.1587301587302, Blast_Score=91, Evalue=7e-20,
Organism=Caenorhabditis elegans, GI17554944, Length=198, Percent_Identity=30.3030303030303, Blast_Score=105, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI25143409, Length=196, Percent_Identity=27.0408163265306, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6320402, Length=200, Percent_Identity=37.5, Blast_Score=105, Evalue=4e-24,
Organism=Drosophila melanogaster, GI24644728, Length=183, Percent_Identity=35.5191256830601, Blast_Score=105, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24658602, Length=196, Percent_Identity=31.1224489795918, Blast_Score=78, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001977 [H]

Pfam domain/function: PF01121 CoaE [H]

EC number: =2.7.1.24 [H]

Molecular weight: Translated: 22790; Mature: 22790

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVLKNAIALTGGIGTGKSTTIKILESQGYEILDADKIAHQLLQEYRFKIAQHFGSEILEK
CCCCCHHHEECCCCCCCCCEEEEEECCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHH
DILNRKKLGAIVFQKANELKWLEDFLHPLIRERMLKKAYELEKNHQAYFLDIPLFFEVGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCEEEEECC
KKRYPVSKVVLIYAPRALQIERLLERDKLKEAEILQRLACQMDIEQKRAMSDYIIDNSSS
CCCCCHHHEEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
LKDLNKQVERFLKTLL
HHHHHHHHHHHHHHHC
>Mature Secondary Structure
MVLKNAIALTGGIGTGKSTTIKILESQGYEILDADKIAHQLLQEYRFKIAQHFGSEILEK
CCCCCHHHEECCCCCCCCCEEEEEECCCCEEECHHHHHHHHHHHHHHHHHHHHHHHHHHH
DILNRKKLGAIVFQKANELKWLEDFLHPLIRERMLKKAYELEKNHQAYFLDIPLFFEVGG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCEEEEECC
KKRYPVSKVVLIYAPRALQIERLLERDKLKEAEILQRLACQMDIEQKRAMSDYIIDNSSS
CCCCCHHHEEEEECCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCHH
LKDLNKQVERFLKTLL
HHHHHHHHHHHHHHHC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]