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The map label for this gene is scoB [H]

Identifier: 108563102

GI number: 108563102

Start: 709603

End: 710226

Strand: Direct

Name: scoB [H]

Synonym: HPAG1_0677

Alternate gene names: 108563102

Gene position: 709603-710226 (Clockwise)

Preceding gene: 108563101

Following gene: 108563103

Centisome position: 44.45

GC content: 44.55

Gene sequence:

>624_bases
ATGAGAGAGGCTATCATTAAAAGAGCGGCAAAGGAATTAAAAGAGGGCATGTATGTGAATTTAGGGATAGGTTTGCCCAC
GCTGGTGGCTAATGAAGTGAGCGGGATGAATATCGTTTTCCAAAGCGAGAACGGGTTATTAGGGATTGGCGCTTACCCTT
TAGAAGGGGGCGTTGATGCGGATCTCATTAATGCAGGAAAGGAAACCATAACCGTGGTGCCGGGCGCTTCGTTTTTTAAT
AGCGCGGATTCGTTTGCGATGATTCGTGGGGGGCATATTGATTTAGCGATTTTAGGAGGGATGGAAGTCTCACAAAATGG
GGATTTGGCTAATTGGATGATCCCTAAAAAGCTCATAAAAGGCATGGGAGGGGCTATGGATTTGGTGCATGGCGCTAAAA
AAGTGATTGTCATCATGGAGCATTGCAACAAATACGGGGAGTCTAAAGTGAAAAAAGAATGCTCATTGCCCTTAACGGGA
AAAGGCGTGGTGCATCAATTGATAACGGATTTAGCGGTGTTTGAATTTTCCAATAACGCCATGAAATTAGTGGAATTGCA
AGAGGGGGTCAGCCTTGATCAAGTGAGAGAAAAAACAGAAGCCGAATTTGAAGTGCACCTATAG

Upstream 100 bases:

>100_bases
ACCCAGATGAAATACACTTGCCAGGAATCTATGTGCAACACATCTATAAGGGCGAGAAATTTGAAAAACGGATAGAAAGA
ATCACTACAAGGAGCGCGAA

Downstream 100 bases:

>100_bases
CTTATAAAAGGGGTGTTTATGTTTTTATTAAGGCATTTGACTTCAGCGTGCGTGTTTTTAGCGTCTAAATGTTTGCCGGA
CTCCTTTGTCTTGGTCACTC

Product: succinyl-CoA-transferase subunit B

Products: NA

Alternate protein names: OXCT B; Succinyl CoA:3-oxoacid CoA-transferase [H]

Number of amino acids: Translated: 207; Mature: 207

Protein sequence:

>207_residues
MREAIIKRAAKELKEGMYVNLGIGLPTLVANEVSGMNIVFQSENGLLGIGAYPLEGGVDADLINAGKETITVVPGASFFN
SADSFAMIRGGHIDLAILGGMEVSQNGDLANWMIPKKLIKGMGGAMDLVHGAKKVIVIMEHCNKYGESKVKKECSLPLTG
KGVVHQLITDLAVFEFSNNAMKLVELQEGVSLDQVREKTEAEFEVHL

Sequences:

>Translated_207_residues
MREAIIKRAAKELKEGMYVNLGIGLPTLVANEVSGMNIVFQSENGLLGIGAYPLEGGVDADLINAGKETITVVPGASFFN
SADSFAMIRGGHIDLAILGGMEVSQNGDLANWMIPKKLIKGMGGAMDLVHGAKKVIVIMEHCNKYGESKVKKECSLPLTG
KGVVHQLITDLAVFEFSNNAMKLVELQEGVSLDQVREKTEAEFEVHL
>Mature_207_residues
MREAIIKRAAKELKEGMYVNLGIGLPTLVANEVSGMNIVFQSENGLLGIGAYPLEGGVDADLINAGKETITVVPGASFFN
SADSFAMIRGGHIDLAILGGMEVSQNGDLANWMIPKKLIKGMGGAMDLVHGAKKVIVIMEHCNKYGESKVKKECSLPLTG
KGVVHQLITDLAVFEFSNNAMKLVELQEGVSLDQVREKTEAEFEVHL

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG2057

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit B family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=208, Percent_Identity=57.2115384615385, Blast_Score=240, Evalue=6e-64,
Organism=Homo sapiens, GI11545841, Length=207, Percent_Identity=54.5893719806763, Blast_Score=230, Evalue=6e-61,
Organism=Escherichia coli, GI1788552, Length=209, Percent_Identity=52.1531100478469, Blast_Score=224, Evalue=2e-60,
Organism=Caenorhabditis elegans, GI17531517, Length=207, Percent_Identity=54.1062801932367, Blast_Score=232, Evalue=1e-61,
Organism=Drosophila melanogaster, GI21358325, Length=208, Percent_Identity=56.7307692307692, Blast_Score=238, Evalue=2e-63,
Organism=Drosophila melanogaster, GI24655794, Length=208, Percent_Identity=56.7307692307692, Blast_Score=238, Evalue=2e-63,

Paralogues:

None

Copy number: 369 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012791
- InterPro:   IPR004165
- InterPro:   IPR004164 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.5 [H]

Molecular weight: Translated: 22242; Mature: 22242

Theoretical pI: Translated: 5.33; Mature: 5.33

Prosite motif: PS01274 COA_TRANSF_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
4.8 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
4.8 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREAIIKRAAKELKEGMYVNLGIGLPTLVANEVSGMNIVFQSENGLLGIGAYPLEGGVDA
CHHHHHHHHHHHHHCCEEEEECCCCHHHHHHCCCCCEEEEECCCCEEEECCCCCCCCCCH
DLINAGKETITVVPGASFFNSADSFAMIRGGHIDLAILGGMEVSQNGDLANWMIPKKLIK
HHHHCCCCEEEEECCCHHHCCCCCEEEEECCCEEEEEECCEEECCCCCCHHHHHHHHHHH
GMGGAMDLVHGAKKVIVIMEHCNKYGESKVKKECSLPLTGKGVVHQLITDLAVFEFSNNA
HCCCHHHHHHCCHHEEEEHHHHHHHCHHHHHHHCCCCCCCHHHHHHHHHHHHHEEECCCC
MKLVELQEGVSLDQVREKTEAEFEVHL
EEEEEECCCCCHHHHHHHCCCEEEEEC
>Mature Secondary Structure
MREAIIKRAAKELKEGMYVNLGIGLPTLVANEVSGMNIVFQSENGLLGIGAYPLEGGVDA
CHHHHHHHHHHHHHCCEEEEECCCCHHHHHHCCCCCEEEEECCCCEEEECCCCCCCCCCH
DLINAGKETITVVPGASFFNSADSFAMIRGGHIDLAILGGMEVSQNGDLANWMIPKKLIK
HHHHCCCCEEEEECCCHHHCCCCCEEEEECCCEEEEEECCEEECCCCCCHHHHHHHHHHH
GMGGAMDLVHGAKKVIVIMEHCNKYGESKVKKECSLPLTGKGVVHQLITDLAVFEFSNNA
HCCCHHHHHHCCHHEEEEHHHHHHHCHHHHHHHCCCCCCCHHHHHHHHHHHHHEEECCCC
MKLVELQEGVSLDQVREKTEAEFEVHL
EEEEEECCCCCHHHHHHHCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]