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The map label for this gene is scoA [H]

Identifier: 108563101

GI number: 108563101

Start: 708908

End: 709606

Strand: Direct

Name: scoA [H]

Synonym: HPAG1_0676

Alternate gene names: 108563101

Gene position: 708908-709606 (Clockwise)

Preceding gene: 108563100

Following gene: 108563102

Centisome position: 44.41

GC content: 43.63

Gene sequence:

>699_bases
ATGAACAAGGTTATAACCGATTTAGACAAAGCATTGAGCGGGTTAAAAGACGGGGACACTATTTTAGTGGGCGGTTTTGG
GCTGTGCGGGATACCCGAATACGCCATTAATTACATTTATAAGAAAGGCATTAAGGATTTGATTGTCGTGAGCAATAATT
GCGGCGTTGATGACTTTGGGTTGGGCATTCTTTTAGAAAAAAAACAGATTAAAAAGATTATCGCTTCCTATGTGGGAGAA
AATAAGATTTTTGAATCGCAAATGCTGAACGGAGAAATTGAAGTCGTTTTGACACCGCAAGGCACGCTAGCTGAAAACTT
GCGCGCTGGAGGGGCTGGGATACCCGCTTACTACACCCCAACCGGTGTTGGGACTTTGATCGCTCAAGGCAAGGAATCAA
GGGAGTTTAACGGCAAAGAGTATATTTTAGAAAGAGCGATCACAGGCGATTACGGGCTTATCAAAGCCTATAAAAGCGAT
ACTTTAGGGAATTTGGTGTTCAGAAAGACAGCCAGGAATTTCAATCCCTTGTGCGCGATGGCGGCAAAAATATGCGTCGC
TGAAGTGGAAGAAATTGTCCCGGCCGGGGAATTAGACCCAGATGAAATACACTTGCCAGGAATCTATGTGCAACACATCT
ATAAGGGCGAGAAATTTGAAAAACGGATAGAAAGAATCACTACAAGGAGCGCGAAATGA

Upstream 100 bases:

>100_bases
GAAATGAAAAGGAGCGGGCATGGCGTGGGTTGCGCGTCATTGTGTGTGGGCGGCGGGCAAGGTCTTTCTGTGGTAGTTGA
ACAAAAATAAGGAGAATGAG

Downstream 100 bases:

>100_bases
GAGAGGCTATCATTAAAAGAGCGGCAAAGGAATTAAAAGAGGGCATGTATGTGAATTTAGGGATAGGTTTGCCCACGCTG
GTGGCTAATGAAGTGAGCGG

Product: succinyl-CoA-transferase subunit A

Products: NA

Alternate protein names: Succinyl CoA:3-oxoacid CoA-transferase; OXCT A [H]

Number of amino acids: Translated: 232; Mature: 232

Protein sequence:

>232_residues
MNKVITDLDKALSGLKDGDTILVGGFGLCGIPEYAINYIYKKGIKDLIVVSNNCGVDDFGLGILLEKKQIKKIIASYVGE
NKIFESQMLNGEIEVVLTPQGTLAENLRAGGAGIPAYYTPTGVGTLIAQGKESREFNGKEYILERAITGDYGLIKAYKSD
TLGNLVFRKTARNFNPLCAMAAKICVAEVEEIVPAGELDPDEIHLPGIYVQHIYKGEKFEKRIERITTRSAK

Sequences:

>Translated_232_residues
MNKVITDLDKALSGLKDGDTILVGGFGLCGIPEYAINYIYKKGIKDLIVVSNNCGVDDFGLGILLEKKQIKKIIASYVGE
NKIFESQMLNGEIEVVLTPQGTLAENLRAGGAGIPAYYTPTGVGTLIAQGKESREFNGKEYILERAITGDYGLIKAYKSD
TLGNLVFRKTARNFNPLCAMAAKICVAEVEEIVPAGELDPDEIHLPGIYVQHIYKGEKFEKRIERITTRSAK
>Mature_232_residues
MNKVITDLDKALSGLKDGDTILVGGFGLCGIPEYAINYIYKKGIKDLIVVSNNCGVDDFGLGILLEKKQIKKIIASYVGE
NKIFESQMLNGEIEVVLTPQGTLAENLRAGGAGIPAYYTPTGVGTLIAQGKESREFNGKEYILERAITGDYGLIKAYKSD
TLGNLVFRKTARNFNPLCAMAAKICVAEVEEIVPAGELDPDEIHLPGIYVQHIYKGEKFEKRIERITTRSAK

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=247, Percent_Identity=56.6801619433198, Blast_Score=281, Evalue=3e-76,
Organism=Homo sapiens, GI11545841, Length=244, Percent_Identity=52.0491803278688, Blast_Score=249, Evalue=2e-66,
Organism=Escherichia coli, GI1788551, Length=218, Percent_Identity=42.2018348623853, Blast_Score=197, Evalue=5e-52,
Organism=Caenorhabditis elegans, GI17531517, Length=244, Percent_Identity=50.4098360655738, Blast_Score=241, Evalue=2e-64,
Organism=Drosophila melanogaster, GI24655794, Length=241, Percent_Identity=54.7717842323651, Blast_Score=261, Evalue=2e-70,
Organism=Drosophila melanogaster, GI21358325, Length=241, Percent_Identity=54.7717842323651, Blast_Score=261, Evalue=2e-70,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.5 [H]

Molecular weight: Translated: 25365; Mature: 25365

Theoretical pI: Translated: 6.54; Mature: 6.54

Prosite motif: PS01273 COA_TRANSF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKVITDLDKALSGLKDGDTILVGGFGLCGIPEYAINYIYKKGIKDLIVVSNNCGVDDFG
CCHHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCC
LGILLEKKQIKKIIASYVGENKIFESQMLNGEIEVVLTPQGTLAENLRAGGAGIPAYYTP
CEEEECHHHHHHHHHHHHCCCHHHHHHHCCCCEEEEECCCCHHHHHHHCCCCCCCCEECC
TGVGTLIAQGKESREFNGKEYILERAITGDYGLIKAYKSDTLGNLVFRKTARNFNPLCAM
CCHHHHHHCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHCCCCHHHHH
AAKICVAEVEEIVPAGELDPDEIHLPGIYVQHIYKGEKFEKRIERITTRSAK
HHHHHHHHHHHHCCCCCCCCCCEECCCHHHHHHHCCHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MNKVITDLDKALSGLKDGDTILVGGFGLCGIPEYAINYIYKKGIKDLIVVSNNCGVDDFG
CCHHHHHHHHHHHCCCCCCEEEECCCCCCCCHHHHHHHHHHHCCCEEEEECCCCCCCCCC
LGILLEKKQIKKIIASYVGENKIFESQMLNGEIEVVLTPQGTLAENLRAGGAGIPAYYTP
CEEEECHHHHHHHHHHHHCCCHHHHHHHCCCCEEEEECCCCHHHHHHHCCCCCCCCEECC
TGVGTLIAQGKESREFNGKEYILERAITGDYGLIKAYKSDTLGNLVFRKTARNFNPLCAM
CCHHHHHHCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHCCCHHHHHHHHHHCCCCHHHHH
AAKICVAEVEEIVPAGELDPDEIHLPGIYVQHIYKGEKFEKRIERITTRSAK
HHHHHHHHHHHHCCCCCCCCCCEECCCHHHHHHHCCHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]